Uterine mullerian adenosareoma is a very rate tumor clinically. Shi et al 1 has reported 9 uterine adenosarcomas among 116 uterine sarcomas during 11 years in West China Second Hospital.It consists of benign or atypic...Uterine mullerian adenosareoma is a very rate tumor clinically. Shi et al 1 has reported 9 uterine adenosarcomas among 116 uterine sarcomas during 11 years in West China Second Hospital.It consists of benign or atypical neoplastic glands within a sarcomatous stroma and represents only 8% of uterine sarcomas.展开更多
Uterine sarcomas (US) are rare mesenchymal tumours accounting approximately for 3%–7% of all uterine cancers. Histologically, US are classified into mesenchymal tumours or mixed epithelial and mesenchymal tumours. Th...Uterine sarcomas (US) are rare mesenchymal tumours accounting approximately for 3%–7% of all uterine cancers. Histologically, US are classified into mesenchymal tumours or mixed epithelial and mesenchymal tumours. The group of mesenchymal tumours includes uterine leiomyosarcoma (uLMS, 65% of cases), endometrial stromal sarcoma (ESS, 21%)– traditionally divided into low grade (LG-ESS) and high grade–undifferentiated uterine sarcoma (5%) and other rare subtypes such as alveolar or embryonal rhabdomyosarcoma. Despite the fact that several drugs demonstrated clinical activity in advanced or metastatic settings, the role of postoperative therapy in US remains controversial. In this review, we have summarised the current state of the art, including the chief trials on adjuvant treatment modalities in US, especially focusing on uLMS, LG-ESS and other rare histotypes.展开更多
Müllerian adenosarcomas are rare mixed tumors with low malignant potential, and occur mainly in the uterus. Primary adenosarcomas arising in vaginal endometriosis are even more rarely reported. We report a very r...Müllerian adenosarcomas are rare mixed tumors with low malignant potential, and occur mainly in the uterus. Primary adenosarcomas arising in vaginal endometriosis are even more rarely reported. We report a very rare case with Müllerian adenosarcoma arising from vaginal endometriosis. A 43-year-old nulliparous woman has a history of endometriosis. Due to two parallel fistulas in cervix, severe endometriosis and adenosarcoma, she has undergone radical and multiple surgeries. After the surgery, persistent vaginal vault masses were noticed, and eight resections of the polyps at vaginal stump were performed. For the first six resections, all the pathological examinations showed endometriosis. And the last two resections demonstrated vaginal adenosarcoma. Transition between Müllerian adenosarcoma and endometriosis was gradual. Finally, adenosarcoma associated with endometriosis was diagnosed from recurrent vaginal masses. To our knowledge, this report is the sixth case that primary adenosarcomas arising in vaginal endometriosis. But chemo-therapy and radiation therapy were not taken and the patient remained in a good condition throughout the 9-year follow-up period. In addition, we present a review of the literature. The diagnosis and treatment of the tumor are also discussed.展开更多
Cervical adenosarcoma was an extremely rare kind of Mullerian mixed tumor,and there was no optimal method of treatment.The aim of this article was to approach the better treatment method for this kind of disease.In th...Cervical adenosarcoma was an extremely rare kind of Mullerian mixed tumor,and there was no optimal method of treatment.The aim of this article was to approach the better treatment method for this kind of disease.In this paper,the vaginal touch,the MRI image,and biopsy were used for diagnosis.And a conservative surgery was performed,followed by 4 cycles of VAC（VCR＋KSM＋CTX） chemotherapy.No evidence of recurrence was seen during follow-up till now.The conservative surgery and VAC chemotherapy in this patient was effective.展开更多
文摘Uterine mullerian adenosareoma is a very rate tumor clinically. Shi et al 1 has reported 9 uterine adenosarcomas among 116 uterine sarcomas during 11 years in West China Second Hospital.It consists of benign or atypical neoplastic glands within a sarcomatous stroma and represents only 8% of uterine sarcomas.
文摘Uterine sarcomas (US) are rare mesenchymal tumours accounting approximately for 3%–7% of all uterine cancers. Histologically, US are classified into mesenchymal tumours or mixed epithelial and mesenchymal tumours. The group of mesenchymal tumours includes uterine leiomyosarcoma (uLMS, 65% of cases), endometrial stromal sarcoma (ESS, 21%)– traditionally divided into low grade (LG-ESS) and high grade–undifferentiated uterine sarcoma (5%) and other rare subtypes such as alveolar or embryonal rhabdomyosarcoma. Despite the fact that several drugs demonstrated clinical activity in advanced or metastatic settings, the role of postoperative therapy in US remains controversial. In this review, we have summarised the current state of the art, including the chief trials on adjuvant treatment modalities in US, especially focusing on uLMS, LG-ESS and other rare histotypes.
文摘Müllerian adenosarcomas are rare mixed tumors with low malignant potential, and occur mainly in the uterus. Primary adenosarcomas arising in vaginal endometriosis are even more rarely reported. We report a very rare case with Müllerian adenosarcoma arising from vaginal endometriosis. A 43-year-old nulliparous woman has a history of endometriosis. Due to two parallel fistulas in cervix, severe endometriosis and adenosarcoma, she has undergone radical and multiple surgeries. After the surgery, persistent vaginal vault masses were noticed, and eight resections of the polyps at vaginal stump were performed. For the first six resections, all the pathological examinations showed endometriosis. And the last two resections demonstrated vaginal adenosarcoma. Transition between Müllerian adenosarcoma and endometriosis was gradual. Finally, adenosarcoma associated with endometriosis was diagnosed from recurrent vaginal masses. To our knowledge, this report is the sixth case that primary adenosarcomas arising in vaginal endometriosis. But chemo-therapy and radiation therapy were not taken and the patient remained in a good condition throughout the 9-year follow-up period. In addition, we present a review of the literature. The diagnosis and treatment of the tumor are also discussed.
文摘Cervical adenosarcoma was an extremely rare kind of Mullerian mixed tumor,and there was no optimal method of treatment.The aim of this article was to approach the better treatment method for this kind of disease.In this paper,the vaginal touch,the MRI image,and biopsy were used for diagnosis.And a conservative surgery was performed,followed by 4 cycles of VAC（VCR＋KSM＋CTX） chemotherapy.No evidence of recurrence was seen during follow-up till now.The conservative surgery and VAC chemotherapy in this patient was effective.
