Abstract The existence of n positive solutions for a class of third-order three-point boundary value problems is investigated, where n is an arbitrary natural number. The main tool is Krasnosel'skii fixed point th...Abstract The existence of n positive solutions for a class of third-order three-point boundary value problems is investigated, where n is an arbitrary natural number. The main tool is Krasnosel'skii fixed point theorem on the cone.展开更多
We study the symmetric positive semidefinite solution of the matrix equation AX_1A^T + BX_2B^T=C. where A is a given real m×n matrix. B is a given real m×p matrix, and C is a given real m×m matrix, with...We study the symmetric positive semidefinite solution of the matrix equation AX_1A^T + BX_2B^T=C. where A is a given real m×n matrix. B is a given real m×p matrix, and C is a given real m×m matrix, with m, n, p positive integers: and the bisymmetric positive semidefinite solution of the matrix equation D^T XD=C, where D is a given real n×m matrix. C is a given real m×m matrix, with m. n positive integers. By making use of the generalized singular value decomposition, we derive general analytic formulae, and present necessary and sufficient conditions for guaranteeing the existence of these solutions.展开更多
This paper proposes a new two-step non-oscillatory shape-preserving positive definite finite difference advection transport scheme, which merges the advantages of small dispersion error in the simple first-order upst... This paper proposes a new two-step non-oscillatory shape-preserving positive definite finite difference advection transport scheme, which merges the advantages of small dispersion error in the simple first-order upstream scheme and small dissipation error in the simple second-order Lax-Wendroff scheme and is completely different from most of present positive definite advection schemes which are based on revising the upstream scheme results. The proposed scheme is much less time consuming than present shape-preserving or non-oscillatory advection transport schemes and produces results which are comparable to the results obtained from the present more complicated schemes. Elementary tests are also presented to examine the behavior of the scheme.展开更多
By means of an abstract continuation theory for k-set contraction and continuation theorem of coincidence degree principle, some criteria are established for the existence of positive periodic solutions of following n...By means of an abstract continuation theory for k-set contraction and continuation theorem of coincidence degree principle, some criteria are established for the existence of positive periodic solutions of following neutral functional differential equation展开更多
The Loess positive and negative terrains (P-N terrains), which are widely distributed on the Loess Plateau, are discussed for the first time by introducing its characteristic, demarcation as well as extraction metho...The Loess positive and negative terrains (P-N terrains), which are widely distributed on the Loess Plateau, are discussed for the first time by introducing its characteristic, demarcation as well as extraction method from high-resolution Digital Elevation Models. Using 5 m-resolution DEMs as original test data, P-N terrains of 48 geomorphological units in different parts of Shaanxi Loess Plateau are extracted accurately. Then six indicators for depicting the geomorphologic landscape and spatial configuration characteristic of P-N terrains are proposed. The spatial distribution rules of these indicators and the relationship between the P-N terrains and Loess relief are discussed for further understanding of Loess landforms. Finally, with the integration of P-N terrains and traditional terrain indices, a series of un-supervised classification methods are applied to make a proper landform classification in northern Shaanxi. Results show that P-N terrains are an effect clue to reveal energy and substance distribution rules on the Loess Plateau. A continuous change of P-N terrains from south to north in Shaanxi Loess Plateau shows an obvious spatial difference of Loess land-forms and the positive terrain area only accounted for 60.5% in this region. The P-N terrains participant landform classification method increases validity of the result, especially in the Loess tableland, Loess tableland-ridge and the Loess low-hill area. This research is significant on the study of Loess landforms with the Digital Terrains Analysis methods.展开更多
The microphysical properties of a long-lasting heavy fog event are examined based on the results from a comprehensive field campaign conducted during the winter of 2006 at Pancheng (32.2°N, 118.7°E), Jiang...The microphysical properties of a long-lasting heavy fog event are examined based on the results from a comprehensive field campaign conducted during the winter of 2006 at Pancheng (32.2°N, 118.7°E), Jiangsu Province, China. It is demonstrated that the key microphysical properties (liquid water content, fog droplet concentration, mean radius and standard deviation) exhibited positive correlations with one another in general, and that the 5-min-average maximum value of fog liquid water content was sometimes greater than 0.5 g m-3. Further analysis shows that the unique combination of positive correlations likely arose from the simultaneous supply of moist air and fog condensation nuclei associated with the advection of warm air, which further led to high liquid water content. High values of liquid water content and droplet concentration conspired to cause low visibility (〈50 m) for a prolonged period of about 40 h. Examination of the microphysical relationships conditioned by the corresponding autoconversion threshold functions shows that the collision-coalescence process was sometimes likely to occur, weakening the positive correlations induced by droplet activation and condensational growth. Statistical analysis shows that the observed droplet size distribution can be described well by the Gamma distribution.展开更多
The existence of positive solutions to second-order Neumann BVPs -u' + Mu = f(t, u), u'(0) = u'(1) = 0 and u' + Mu = f(t, u), u'(0) =u'(1) is proved by a simple application of a Fixed Poin...The existence of positive solutions to second-order Neumann BVPs -u' + Mu = f(t, u), u'(0) = u'(1) = 0 and u' + Mu = f(t, u), u'(0) =u'(1) is proved by a simple application of a Fixed Point Theorem in cones due to Krasnoselskii[1,6].展开更多
Frequent shifts of output and operating mode require a pump turbine with excellent stability. Current researches show that large partial flow conditions in pump mode experience positive-slope phenomena with a large he...Frequent shifts of output and operating mode require a pump turbine with excellent stability. Current researches show that large partial flow conditions in pump mode experience positive-slope phenomena with a large head drop. The pressure fluctuation at the positive slope is crucial to the pump turbine unit safety. The operating instabilities at large partial flow conditions for a pump turbine are analyzed. The hydraulic performance of a model pump turbine is tested with the pressure fluctuations measured at unstable operating points near a positive slope in the performance curve. The hydraulic performance tests show that there are two separated positive-slope regions for the pump turbine, with the flow discharge for the first positive slope from 0.85 to 0.91 times that at the maximum efficiency point. The amplitudes of the pressure fluctuations at these unstable large partial flow conditions near the first positive slope are much larger than those at stable operating condtions. A dominant frequency is measured at 0.2 times the impeller rotational frequency in the flow passage near the impeller exit, which is believed to be induced by the rotating stall in the flow passage of the wicket gates. The test results also show hysteresis with pressure fluctuations when the pump turbine is operated near the first positive slope. The hysteresis creates different pressure fluctuations for those operation points even though their flow rates and heads are similar respectively. The pressure fluctuation characteristics at large partial flow conditions obtained by the present study will be helpful for the safe operation of pumped storage units.展开更多
Background Although severe encephalopathy has been proposed as a possible contraindication to the use of noninvasive positive-pressure ventilation (NPPV), increasing clinical reports showed it was effective in patie...Background Although severe encephalopathy has been proposed as a possible contraindication to the use of noninvasive positive-pressure ventilation (NPPV), increasing clinical reports showed it was effective in patients with impaired consciousness and even coma secondary to acute respiratory failure, especially hypercapnic acute respiratory failure (HARF). To further evaluate the effectiveness and safety of NPPV for severe hypercapnic encephalopathy, a prospective case-control study was conducted at a university respiratory intensive care unit (RICU) in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) during the past 3 years. Methods Forty-three of 68 consecutive AECOPD patients requiring ventilatory support for HARF were divided into 2 groups, which were carefully matched for age, sex, COPD course, tobacco use and previous hospitalization history, according to the severity of encephalopathy, 22 patients with Glasgow coma scale (GCS) 〈10 served as group A and 21 with GCS 〉10 as group B. Results Compared with group B, group A had a higher level of baseline arterial partial CO2 pressure ((102±27) mmHg vs (74±17) mmHg, P〈0.01), lower levels of GCS (7.5±1.9 vs 12.2±1.8, P〈0.01), arterial pH value (7.18±0.06 vs 7.28±0.07, P〈0.01) and partial 02 pressure/fraction of inspired 02 ratio (168±39 vs 189±33, P〈0.05). The NPPV success rate and hospital mortality were 73% (16/22) and 14% (3/22) respectively in group A, which were comparable to those in group B (68% (15/21) and 14% (3/21) respectively, all P〉0.05), but group A needed an average of 7 cmH20 higher of maximal pressure support during NPPV, and 4, 4 and 7 days longer of NPPV time, RICU stay and hospital stay respectively than group B (P〈0.05 or P〈0.01). NPPV therapy failed in 12 patients (6 in each group) because of excessive airway secretions (7 patients), hemodynamic instability (2), worsening of dyspnea and deterioration of ga展开更多
The existence of positive solutions to second-order periodic BVPs-u'+Mu =j(t, u),t(0) = u(2π),u'(0) = '(2π) and u'+ Mu = I(t, u), u(0) = u(2π), u'(0) = u'(2π)is proved by a simple appliCati...The existence of positive solutions to second-order periodic BVPs-u'+Mu =j(t, u),t(0) = u(2π),u'(0) = '(2π) and u'+ Mu = I(t, u), u(0) = u(2π), u'(0) = u'(2π)is proved by a simple appliCation of a Fixed point Theorem in cones due to Krasnoselskii.展开更多
Background: For patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) and type 2 diabetes mellitus (T2DM), the night sleep interruption and intermittent hypoxia due to apnea or hypopnea may induce glyce...Background: For patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) and type 2 diabetes mellitus (T2DM), the night sleep interruption and intermittent hypoxia due to apnea or hypopnea may induce glycemic excursions and reduce insulin sensitivity. This study aimed to investigate the effect of continuous positive airway pressure (CPAP) therapy in patients with OSAHS and T2DM. Methods: Continuous glucose monitoring system (CGMS) was used in 40 patients with T2DM and newly diagnosed OSAHS. The measurements were repeated after 30 days of CPAP treatment. Subsequently, insulin sensitivity and glycohemoglobin (HbAlc) were measured and compared to the pretreatment data. Results: After CPAP therapy, the CGMS indicators showed that the 24-h mean blood glucose (MBG) and the night time MBG were significantly reduced (P 〈 0.05 and P = 0.03, respectively). The mean ambulatory glucose excursions (MAGEs) and the mean of daily differences were also significantly reduced (P 〈 0.05 and P = 0.002, respectively) compared to pretreatment levels. During the night, MAGE also significantly decreased (P = 0.049). The differences between the highest and lowest levels of blood glucose over 24 h and during the night were significantly lower than prior to CPAP treatment (P 〈 0.05 and P = 0.024, respectively). The 24 h and night time durations of high blood glucose (〉7.8 mmol/L and 〉 11.1 mmol/L) decreased (P 〈 0.05 and P 〈 0.05, respectively) after the treatment. In addition, HbA 1 c levels were also lower than those before treatment (P 〈 0.05), and the homeostasis model assessment index of insulin resistance was also significantly lower than before CPAP treatment (P = 0.034). Conclusions: CPAP therapy may have a beneficial effect on improving not only blood glucose but also upon insulin sensitivity in T2DM patients with OSAHS. This suggests that CPAP may be an effective treatment for T2DM in addition to intensive diabetes management.展开更多
Size segragated samples were collected during high polluted winter haze days in 2006 in Beijing, China. Twenty nine elements and 9 water soluble ions were determined. Heavy metals of Zn, Pb, Mn, Cu, As, Cr, Ni, V and ...Size segragated samples were collected during high polluted winter haze days in 2006 in Beijing, China. Twenty nine elements and 9 water soluble ions were determined. Heavy metals of Zn, Pb, Mn, Cu, As, Cr, Ni, V and Cd were deeply studied considering their toxic effect on human being. Among these heavy metals, the levels of Mn, As and Cd exceeded the reference values of National Ambient Air Quality Standard (GB3095-2012) and guidelines of World Health Organization. By estimation, high percentage of atmospheric heavy metals in PM2.5 indicates it is an effective way to control atmospheric heavy metals by PM2.5 controlling. Pb, Cd, and Zn show mostly in accumulation mode, V, Mn and Cu exist mostly in both coarse and accumulation modes, and Ni and Cr exist in all of the three modes. Considering the health effect, the breakthrough rates of atmospheric heavy metals into pulmonary alveoli are: Pb (62.1%) 〉 As (58.1%) 〉 Cd (57.9%) 〉 Zn (57.7%) 〉 Cu (55.8%) 〉 Ni (53.5%) 〉 Cr (52.2%) 〉 Mn (49.2%) 〉 V (43.5%). Positive matrix factorization method was applied for source apportionment of studied heavy metals combined with some marker elements and ions such as K, As, SO42- etc., and four factors (dust, vehicle, aged and transportation, unknown) are identified and the size distribution contribution of them to atmospheric heavy metals are discussed.展开更多
Big Personal Data is growing explosively. Consequently, an increasing number of internet users are drowning in a sea of data. Big Personal Data has enormous commercial value; it is a new kind of data asset. An urgent ...Big Personal Data is growing explosively. Consequently, an increasing number of internet users are drowning in a sea of data. Big Personal Data has enormous commercial value; it is a new kind of data asset. An urgent problem has thus arisen in the data market: How to price Big Personal Data fairly and reasonably. This paper proposes a pricing model for Big Personal Data based on tuple granularity, with the help of comparative analysis of existing data pricing models and strategies. This model is put forward to implement positive rating and reverse pricing for Big Personal Data by investigating data attributes that affect data value, and analyzing how the value of data tuples varies with information entropy, weight value, data reference index, cost, and other factors. The model can be adjusted dynamically according to these parameters. With increases in data scale, reductions in its cost,and improvements in its quality, Big Personal Data users can thereby obtain greater benefits.展开更多
By means of an abstract continuation theorem, the existence criteria are established for the positive periodic solutions of a neutral functional differential equation d N d t=N(t)[a(t)-β(t)N(t)-b(t)N(t-σ(t))-c(...By means of an abstract continuation theorem, the existence criteria are established for the positive periodic solutions of a neutral functional differential equation d N d t=N(t)[a(t)-β(t)N(t)-b(t)N(t-σ(t))-c(t)N′(t-τ(t))].展开更多
Constructing a family of generalized Lyapunov functions, a new method is proposed to obtain new global attractive set and positive invariant set of the Lorenz chaotic system. The method we proposed greatly simplifies ...Constructing a family of generalized Lyapunov functions, a new method is proposed to obtain new global attractive set and positive invariant set of the Lorenz chaotic system. The method we proposed greatly simplifies the complex proofs of the two famous estimations presented by the Russian scholar Leonov. Our uniform formula can derive a series of the new estimations. Employing the idea of intersection in set theory, we extract a new Leonov formula-like estimation from the family of the estimations. With our method and the new estimation, one can confirm that there are no equilibrium, periodic solutions, almost periodic motions, wandering motions or other chaotic attractors outside the global attractive set. The Lorenz butterfly-like singular attractors are located in the global attractive set only. This result is applied to the chaos control and chaos synchronization. Some feedback control laws are obtained to guarantee that all the trajectories of the Lorenz systems track a periodic solution, or globally stabilize an unstable (or locally stable but not globally asymptotically stable) equilibrium. Further, some new global exponential chaos synchronization results are presented. Our new method and the new results are expected to be applied in real secure communication systems.展开更多
文本分类是信息检索的关键问题之一.提取更多的可信反例和构造准确高效的分类器是PU(positive and unlabeled)文本分类的两个重要问题.然而,在现有的可信反例提取方法中,很多方法提取的可信反例数量较少,构建的分类器质量有待提高.分别...文本分类是信息检索的关键问题之一.提取更多的可信反例和构造准确高效的分类器是PU(positive and unlabeled)文本分类的两个重要问题.然而,在现有的可信反例提取方法中,很多方法提取的可信反例数量较少,构建的分类器质量有待提高.分别针对这两个重要步骤提供了一种基于聚类的半监督主动分类方法.与传统的反例提取方法不同,利用聚类技术和正例文档应与反例文档共享尽可能少的特征项这一特点,从未标识数据集中尽可能多地移除正例,从而可以获得更多的可信反例.结合SVM主动学习和改进的Rocchio构建分类器,并采用改进的TFIDF(term frequency inverse document frequency)进行特征提取,可以显著提高分类的准确度.分别在3个不同的数据集中测试了分类结果(RCV1,Reuters-21578,20 Newsgoups).实验结果表明,基于聚类寻找可信反例可以在保持较低错误率的情况下获取更多的可信反例,而且主动学习方法的引入也显著提升了分类精度.展开更多
文摘Abstract The existence of n positive solutions for a class of third-order three-point boundary value problems is investigated, where n is an arbitrary natural number. The main tool is Krasnosel'skii fixed point theorem on the cone.
基金Subsidized by the Special Funds for Major State Basic Research Projects G1999032803
文摘We study the symmetric positive semidefinite solution of the matrix equation AX_1A^T + BX_2B^T=C. where A is a given real m×n matrix. B is a given real m×p matrix, and C is a given real m×m matrix, with m, n, p positive integers: and the bisymmetric positive semidefinite solution of the matrix equation D^T XD=C, where D is a given real n×m matrix. C is a given real m×m matrix, with m. n positive integers. By making use of the generalized singular value decomposition, we derive general analytic formulae, and present necessary and sufficient conditions for guaranteeing the existence of these solutions.
基金This work is supported by the Ntional Natural Science Foundation of China.
文摘 This paper proposes a new two-step non-oscillatory shape-preserving positive definite finite difference advection transport scheme, which merges the advantages of small dispersion error in the simple first-order upstream scheme and small dissipation error in the simple second-order Lax-Wendroff scheme and is completely different from most of present positive definite advection schemes which are based on revising the upstream scheme results. The proposed scheme is much less time consuming than present shape-preserving or non-oscillatory advection transport schemes and produces results which are comparable to the results obtained from the present more complicated schemes. Elementary tests are also presented to examine the behavior of the scheme.
基金Supported by the National Natural Science Foundation of China (No.19871005).
文摘By means of an abstract continuation theory for k-set contraction and continuation theorem of coincidence degree principle, some criteria are established for the existence of positive periodic solutions of following neutral functional differential equation
基金Key Project of National Natural Science Foundation of China, No.40930531 National Youth Science Foundation of China, No.40801148 Anhui Provincial Natural Science Foundation. No. 090412062
文摘The Loess positive and negative terrains (P-N terrains), which are widely distributed on the Loess Plateau, are discussed for the first time by introducing its characteristic, demarcation as well as extraction method from high-resolution Digital Elevation Models. Using 5 m-resolution DEMs as original test data, P-N terrains of 48 geomorphological units in different parts of Shaanxi Loess Plateau are extracted accurately. Then six indicators for depicting the geomorphologic landscape and spatial configuration characteristic of P-N terrains are proposed. The spatial distribution rules of these indicators and the relationship between the P-N terrains and Loess relief are discussed for further understanding of Loess landforms. Finally, with the integration of P-N terrains and traditional terrain indices, a series of un-supervised classification methods are applied to make a proper landform classification in northern Shaanxi. Results show that P-N terrains are an effect clue to reveal energy and substance distribution rules on the Loess Plateau. A continuous change of P-N terrains from south to north in Shaanxi Loess Plateau shows an obvious spatial difference of Loess land-forms and the positive terrain area only accounted for 60.5% in this region. The P-N terrains participant landform classification method increases validity of the result, especially in the Loess tableland, Loess tableland-ridge and the Loess low-hill area. This research is significant on the study of Loess landforms with the Digital Terrains Analysis methods.
基金mainly provided by the National Natural Science Foundation of China (Grant Nos. 40537034 and 40775012)the Natural Science Fund for Universities in Jiangsu Province(Grant Nos. 06KJA17021 and 08KJA170002)+1 种基金the Meteorology Fund of the Ministry of Science and Technology [Grant No. GYHY (QX) 2007-6-26]the Qing-Lan Project for cloud-fog-precipitation-aerosol study in Jiangsu Province and the Graduate Student Innovation Plan in the Universities of Jiangsu Province (CX09B 226Z)
文摘The microphysical properties of a long-lasting heavy fog event are examined based on the results from a comprehensive field campaign conducted during the winter of 2006 at Pancheng (32.2°N, 118.7°E), Jiangsu Province, China. It is demonstrated that the key microphysical properties (liquid water content, fog droplet concentration, mean radius and standard deviation) exhibited positive correlations with one another in general, and that the 5-min-average maximum value of fog liquid water content was sometimes greater than 0.5 g m-3. Further analysis shows that the unique combination of positive correlations likely arose from the simultaneous supply of moist air and fog condensation nuclei associated with the advection of warm air, which further led to high liquid water content. High values of liquid water content and droplet concentration conspired to cause low visibility (〈50 m) for a prolonged period of about 40 h. Examination of the microphysical relationships conditioned by the corresponding autoconversion threshold functions shows that the collision-coalescence process was sometimes likely to occur, weakening the positive correlations induced by droplet activation and condensational growth. Statistical analysis shows that the observed droplet size distribution can be described well by the Gamma distribution.
文摘The existence of positive solutions to second-order Neumann BVPs -u' + Mu = f(t, u), u'(0) = u'(1) = 0 and u' + Mu = f(t, u), u'(0) =u'(1) is proved by a simple application of a Fixed Point Theorem in cones due to Krasnoselskii[1,6].
基金supported by National Natural Science Foundation of China(Grant No. 50976061)State Key Laboratory of Hydroscience and Engineering of China(Grant No. 2010-ZY-4)Beijing Municipal Natural Science Foundation of China(Grant No. 3072008)
文摘Frequent shifts of output and operating mode require a pump turbine with excellent stability. Current researches show that large partial flow conditions in pump mode experience positive-slope phenomena with a large head drop. The pressure fluctuation at the positive slope is crucial to the pump turbine unit safety. The operating instabilities at large partial flow conditions for a pump turbine are analyzed. The hydraulic performance of a model pump turbine is tested with the pressure fluctuations measured at unstable operating points near a positive slope in the performance curve. The hydraulic performance tests show that there are two separated positive-slope regions for the pump turbine, with the flow discharge for the first positive slope from 0.85 to 0.91 times that at the maximum efficiency point. The amplitudes of the pressure fluctuations at these unstable large partial flow conditions near the first positive slope are much larger than those at stable operating condtions. A dominant frequency is measured at 0.2 times the impeller rotational frequency in the flow passage near the impeller exit, which is believed to be induced by the rotating stall in the flow passage of the wicket gates. The test results also show hysteresis with pressure fluctuations when the pump turbine is operated near the first positive slope. The hysteresis creates different pressure fluctuations for those operation points even though their flow rates and heads are similar respectively. The pressure fluctuation characteristics at large partial flow conditions obtained by the present study will be helpful for the safe operation of pumped storage units.
文摘Background Although severe encephalopathy has been proposed as a possible contraindication to the use of noninvasive positive-pressure ventilation (NPPV), increasing clinical reports showed it was effective in patients with impaired consciousness and even coma secondary to acute respiratory failure, especially hypercapnic acute respiratory failure (HARF). To further evaluate the effectiveness and safety of NPPV for severe hypercapnic encephalopathy, a prospective case-control study was conducted at a university respiratory intensive care unit (RICU) in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) during the past 3 years. Methods Forty-three of 68 consecutive AECOPD patients requiring ventilatory support for HARF were divided into 2 groups, which were carefully matched for age, sex, COPD course, tobacco use and previous hospitalization history, according to the severity of encephalopathy, 22 patients with Glasgow coma scale (GCS) 〈10 served as group A and 21 with GCS 〉10 as group B. Results Compared with group B, group A had a higher level of baseline arterial partial CO2 pressure ((102±27) mmHg vs (74±17) mmHg, P〈0.01), lower levels of GCS (7.5±1.9 vs 12.2±1.8, P〈0.01), arterial pH value (7.18±0.06 vs 7.28±0.07, P〈0.01) and partial 02 pressure/fraction of inspired 02 ratio (168±39 vs 189±33, P〈0.05). The NPPV success rate and hospital mortality were 73% (16/22) and 14% (3/22) respectively in group A, which were comparable to those in group B (68% (15/21) and 14% (3/21) respectively, all P〉0.05), but group A needed an average of 7 cmH20 higher of maximal pressure support during NPPV, and 4, 4 and 7 days longer of NPPV time, RICU stay and hospital stay respectively than group B (P〈0.05 or P〈0.01). NPPV therapy failed in 12 patients (6 in each group) because of excessive airway secretions (7 patients), hemodynamic instability (2), worsening of dyspnea and deterioration of ga
文摘The existence of positive solutions to second-order periodic BVPs-u'+Mu =j(t, u),t(0) = u(2π),u'(0) = '(2π) and u'+ Mu = I(t, u), u(0) = u(2π), u'(0) = u'(2π)is proved by a simple appliCation of a Fixed point Theorem in cones due to Krasnoselskii.
文摘Background: For patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) and type 2 diabetes mellitus (T2DM), the night sleep interruption and intermittent hypoxia due to apnea or hypopnea may induce glycemic excursions and reduce insulin sensitivity. This study aimed to investigate the effect of continuous positive airway pressure (CPAP) therapy in patients with OSAHS and T2DM. Methods: Continuous glucose monitoring system (CGMS) was used in 40 patients with T2DM and newly diagnosed OSAHS. The measurements were repeated after 30 days of CPAP treatment. Subsequently, insulin sensitivity and glycohemoglobin (HbAlc) were measured and compared to the pretreatment data. Results: After CPAP therapy, the CGMS indicators showed that the 24-h mean blood glucose (MBG) and the night time MBG were significantly reduced (P 〈 0.05 and P = 0.03, respectively). The mean ambulatory glucose excursions (MAGEs) and the mean of daily differences were also significantly reduced (P 〈 0.05 and P = 0.002, respectively) compared to pretreatment levels. During the night, MAGE also significantly decreased (P = 0.049). The differences between the highest and lowest levels of blood glucose over 24 h and during the night were significantly lower than prior to CPAP treatment (P 〈 0.05 and P = 0.024, respectively). The 24 h and night time durations of high blood glucose (〉7.8 mmol/L and 〉 11.1 mmol/L) decreased (P 〈 0.05 and P 〈 0.05, respectively) after the treatment. In addition, HbA 1 c levels were also lower than those before treatment (P 〈 0.05), and the homeostasis model assessment index of insulin resistance was also significantly lower than before CPAP treatment (P = 0.034). Conclusions: CPAP therapy may have a beneficial effect on improving not only blood glucose but also upon insulin sensitivity in T2DM patients with OSAHS. This suggests that CPAP may be an effective treatment for T2DM in addition to intensive diabetes management.
基金supported by the National Natural Science Foundation of China(No.41105111,41275134)the National Department Public Benefit Research Foundation(MEP)(No.201109005)the Research Found of CRAES(No.2012ysky09)
文摘Size segragated samples were collected during high polluted winter haze days in 2006 in Beijing, China. Twenty nine elements and 9 water soluble ions were determined. Heavy metals of Zn, Pb, Mn, Cu, As, Cr, Ni, V and Cd were deeply studied considering their toxic effect on human being. Among these heavy metals, the levels of Mn, As and Cd exceeded the reference values of National Ambient Air Quality Standard (GB3095-2012) and guidelines of World Health Organization. By estimation, high percentage of atmospheric heavy metals in PM2.5 indicates it is an effective way to control atmospheric heavy metals by PM2.5 controlling. Pb, Cd, and Zn show mostly in accumulation mode, V, Mn and Cu exist mostly in both coarse and accumulation modes, and Ni and Cr exist in all of the three modes. Considering the health effect, the breakthrough rates of atmospheric heavy metals into pulmonary alveoli are: Pb (62.1%) 〉 As (58.1%) 〉 Cd (57.9%) 〉 Zn (57.7%) 〉 Cu (55.8%) 〉 Ni (53.5%) 〉 Cr (52.2%) 〉 Mn (49.2%) 〉 V (43.5%). Positive matrix factorization method was applied for source apportionment of studied heavy metals combined with some marker elements and ions such as K, As, SO42- etc., and four factors (dust, vehicle, aged and transportation, unknown) are identified and the size distribution contribution of them to atmospheric heavy metals are discussed.
基金supported in part by the National Natural Science Foundation of China (Nos. 61332001, 61272104, and 61472050)the Science and Technology Planning Project of Sichuan Province (Nos. 2014JY0257, 2015GZ0103, and 2014-HM01-00326SF)
文摘Big Personal Data is growing explosively. Consequently, an increasing number of internet users are drowning in a sea of data. Big Personal Data has enormous commercial value; it is a new kind of data asset. An urgent problem has thus arisen in the data market: How to price Big Personal Data fairly and reasonably. This paper proposes a pricing model for Big Personal Data based on tuple granularity, with the help of comparative analysis of existing data pricing models and strategies. This model is put forward to implement positive rating and reverse pricing for Big Personal Data by investigating data attributes that affect data value, and analyzing how the value of data tuples varies with information entropy, weight value, data reference index, cost, and other factors. The model can be adjusted dynamically according to these parameters. With increases in data scale, reductions in its cost,and improvements in its quality, Big Personal Data users can thereby obtain greater benefits.
基金National Natural Science Foundation of China( 198710 0 5 )
文摘By means of an abstract continuation theorem, the existence criteria are established for the positive periodic solutions of a neutral functional differential equation d N d t=N(t)[a(t)-β(t)N(t)-b(t)N(t-σ(t))-c(t)N′(t-τ(t))].
基金This work was supported by the National Natural Science Foundation of China(Grant Nos.60274007,60474011)the Guangdong Povince Science Foundation for Program of Research Team(Grant No.04205783).
文摘Constructing a family of generalized Lyapunov functions, a new method is proposed to obtain new global attractive set and positive invariant set of the Lorenz chaotic system. The method we proposed greatly simplifies the complex proofs of the two famous estimations presented by the Russian scholar Leonov. Our uniform formula can derive a series of the new estimations. Employing the idea of intersection in set theory, we extract a new Leonov formula-like estimation from the family of the estimations. With our method and the new estimation, one can confirm that there are no equilibrium, periodic solutions, almost periodic motions, wandering motions or other chaotic attractors outside the global attractive set. The Lorenz butterfly-like singular attractors are located in the global attractive set only. This result is applied to the chaos control and chaos synchronization. Some feedback control laws are obtained to guarantee that all the trajectories of the Lorenz systems track a periodic solution, or globally stabilize an unstable (or locally stable but not globally asymptotically stable) equilibrium. Further, some new global exponential chaos synchronization results are presented. Our new method and the new results are expected to be applied in real secure communication systems.
文摘文本分类是信息检索的关键问题之一.提取更多的可信反例和构造准确高效的分类器是PU(positive and unlabeled)文本分类的两个重要问题.然而,在现有的可信反例提取方法中,很多方法提取的可信反例数量较少,构建的分类器质量有待提高.分别针对这两个重要步骤提供了一种基于聚类的半监督主动分类方法.与传统的反例提取方法不同,利用聚类技术和正例文档应与反例文档共享尽可能少的特征项这一特点,从未标识数据集中尽可能多地移除正例,从而可以获得更多的可信反例.结合SVM主动学习和改进的Rocchio构建分类器,并采用改进的TFIDF(term frequency inverse document frequency)进行特征提取,可以显著提高分类的准确度.分别在3个不同的数据集中测试了分类结果(RCV1,Reuters-21578,20 Newsgoups).实验结果表明,基于聚类寻找可信反例可以在保持较低错误率的情况下获取更多的可信反例,而且主动学习方法的引入也显著提升了分类精度.