Traditional Chinese medicine （TCM） is gaining popularity in the treatment of psychiatric disorders that can be described and treated from either an Eastern or a Western perspective. In Eastern medicine, the disorder...Traditional Chinese medicine （TCM） is gaining popularity in the treatment of psychiatric disorders that can be described and treated from either an Eastern or a Western perspective. In Eastern medicine, the disorders are described according to five diagnostic methods that are used in TCM： inspection, auscultation, olfaction, inquiry, and palpation, including tongue and pulse diagnosis.展开更多
OBJCTIVE: To compare the clinical efficacy of Traditional Chinese Medicine(TCM) to Western Medicine in the treatment of primary Sj?gren's syndrome(p SS).METHODS: We collected randomized controlled trials of TCM vs...OBJCTIVE: To compare the clinical efficacy of Traditional Chinese Medicine(TCM) to Western Medicine in the treatment of primary Sj?gren's syndrome(p SS).METHODS: We collected randomized controlled trials of TCM vs Western Medicine for the treatment of p SS in Chinese and foreign databases. The study quality was evaluated as suggested in the Cochrane Handbook. The Meta-analysis was performed using Review Manager 5.0 statistical software.RESULTS: A total of 31 randomized controlled trials with 2137 cases were retrieved. The efficiencies of TCM and control treatments were 87.18% and65.63%, respectively. The results of heterogeneity tests showed that the data were homogeneous(P = 0.83), thus a fixed effects model was used for analysis. The results revealed an odds ratio of 3.74 with a 95% confidence interval of 2.99-4.69. The overall effectiveness value was 11.48(P < 0.000 01).These results suggest the efficacy of TCM therapy for p SS better than Western Medicine.CONCLUSION: Although our findings reveal that the TCM treatment of p SS had significant advantages over its counterpart, there were some flaws in the studies included. The findings warrant further investigation.展开更多
OBJECTIVE: To conduct a review of the systematic reviews and meta-analyses on the Traditional Chinese Medicine(TCM) treatment of type 2 diabetes mellitus(T2DM).METHODS: We searched Pub Med, Cochrane, Web of Science, C...OBJECTIVE: To conduct a review of the systematic reviews and meta-analyses on the Traditional Chinese Medicine(TCM) treatment of type 2 diabetes mellitus(T2DM).METHODS: We searched Pub Med, Cochrane, Web of Science, Chinese Biomedical Literature Database(CBM), China National Knowledge Infrastructure(CNKI), China Science and Technology Journal Database(VIP), Wanfang, and other databases from database inception to May 2014 for systematic reviews and meta-analyses on TCM treatment of T2 DM. Manuscripts were read by two investigators if they met the inclusion criteria, and data were extracted. A Measurement Tool to Assess Systematic Reviews(AMSTAR) was used to classify research quality, and the evidence quality was graded by the Grade of Recommendation, Assessment, Development, and Evaluation(GRADE) system.RESULTS: Eighteen systematic reviews and meta-analyses were considered. Fifteen analyzed the efficacy of Chinese herbal medicines, and three investigated the efficacy of acupuncture. AMSTAR evaluation ranged from 3-10, and re-evaluation of the main results implied that treatment of T2 DM with TCM has certain advantages when compared with conventional Western medicine. However, the evidence quality was generally low.CONCLUSION: This work shows favorable evidence for the clinical treatment of TCM on T2 DM. However, it is recommended that evidence-based decisions are made based on clinical trials because of the GRADE scores of the studies. To achieve higher quality of clinical research, clinical research on TCM requires specific and suitable research methods. Further trials may increase the quality of evidence to evaluate the clinical efficacy of TCM for T2 DM.展开更多
文摘Traditional Chinese medicine （TCM） is gaining popularity in the treatment of psychiatric disorders that can be described and treated from either an Eastern or a Western perspective. In Eastern medicine, the disorders are described according to five diagnostic methods that are used in TCM： inspection, auscultation, olfaction, inquiry, and palpation, including tongue and pulse diagnosis.
基金Supported by Grants from the National Natural Science Foundation of China(Study Icariin Improving Aging Lipid Metabolism Mechanisms Based On Nuclear Receptor PPARβand Network Pharmacology,No.81673724)TCM Department of Chongqing Municipal Health and Family Planning Commission(Based on the Theory of"Kidney is Congenital Essence"to Study the Epigenetic Mechanisms on Preventing and Treating Lupus,No.2012-1-6.Comparative Clinical Efficacy of Clearing Heat Removing Dampness Chinese Herbal Formulations Particles and Pieces to Treat Gout,No.2012-1-16)+1 种基金the Program for Introducing Talents of Chongqing Hospital of TCM(2011-001)Chongqing Science and Technology Commission(Integration and Demonstration of Chinese Medicine Technical Characteristics on Prevention And Treatment of Rheumatism Disease,No.cstc2013jcsf10012.Study Reinforcing Kidney Sequential Therapy to Prevent and Treat Hormone Side Effects and Dependence,No.cstc2015jbky330025011)
文摘OBJCTIVE: To compare the clinical efficacy of Traditional Chinese Medicine(TCM) to Western Medicine in the treatment of primary Sj?gren's syndrome(p SS).METHODS: We collected randomized controlled trials of TCM vs Western Medicine for the treatment of p SS in Chinese and foreign databases. The study quality was evaluated as suggested in the Cochrane Handbook. The Meta-analysis was performed using Review Manager 5.0 statistical software.RESULTS: A total of 31 randomized controlled trials with 2137 cases were retrieved. The efficiencies of TCM and control treatments were 87.18% and65.63%, respectively. The results of heterogeneity tests showed that the data were homogeneous(P = 0.83), thus a fixed effects model was used for analysis. The results revealed an odds ratio of 3.74 with a 95% confidence interval of 2.99-4.69. The overall effectiveness value was 11.48(P < 0.000 01).These results suggest the efficacy of TCM therapy for p SS better than Western Medicine.CONCLUSION: Although our findings reveal that the TCM treatment of p SS had significant advantages over its counterpart, there were some flaws in the studies included. The findings warrant further investigation.
基金Supported by the National Natural Science Foundation of China(No.30873307,81373749,81574071)the People Programme(Marie Curie Actions)of the European Union's Seventh Framework Programme under REA grant agreement(No.PIRSES-GA-2013-612589)
文摘OBJECTIVE: To conduct a review of the systematic reviews and meta-analyses on the Traditional Chinese Medicine(TCM) treatment of type 2 diabetes mellitus(T2DM).METHODS: We searched Pub Med, Cochrane, Web of Science, Chinese Biomedical Literature Database(CBM), China National Knowledge Infrastructure(CNKI), China Science and Technology Journal Database(VIP), Wanfang, and other databases from database inception to May 2014 for systematic reviews and meta-analyses on TCM treatment of T2 DM. Manuscripts were read by two investigators if they met the inclusion criteria, and data were extracted. A Measurement Tool to Assess Systematic Reviews(AMSTAR) was used to classify research quality, and the evidence quality was graded by the Grade of Recommendation, Assessment, Development, and Evaluation(GRADE) system.RESULTS: Eighteen systematic reviews and meta-analyses were considered. Fifteen analyzed the efficacy of Chinese herbal medicines, and three investigated the efficacy of acupuncture. AMSTAR evaluation ranged from 3-10, and re-evaluation of the main results implied that treatment of T2 DM with TCM has certain advantages when compared with conventional Western medicine. However, the evidence quality was generally low.CONCLUSION: This work shows favorable evidence for the clinical treatment of TCM on T2 DM. However, it is recommended that evidence-based decisions are made based on clinical trials because of the GRADE scores of the studies. To achieve higher quality of clinical research, clinical research on TCM requires specific and suitable research methods. Further trials may increase the quality of evidence to evaluate the clinical efficacy of TCM for T2 DM.
