Objective: We studied the application of CT image fusion in the evaluation of radiation treatment planning for non-small cell lung cancer (NSCLC). Methods: Eleven patients with NSCLC, who were treated with three-dimen...Objective: We studied the application of CT image fusion in the evaluation of radiation treatment planning for non-small cell lung cancer (NSCLC). Methods: Eleven patients with NSCLC, who were treated with three-dimensional con-formal radiation therapy, were studied. Each patient underwent twice sequential planning CT scan, i.e., at pre-treatment, and at mid-treatment for field reduction planning. Three treatment plans were established in each patient: treatment plan A was based on the pre-treatment planning CT scans for the first course of treatment, plan B on the mid-treatment planning CT scans for the second course of treatment, and treatment plan F on the fused images for the whole treatment. The irradiation doses received by organs at risk in the whole treatment with treatment A and B plans were estimated by the plus of the parameters in treatment plan A and B, assuming that the parameters involve the different tissues (i.e. V20=AV20+BV20), or the same tissues within an organ (i.e. Dmax=ADmax+BDmax). The assessment parameters in the treatment plan F were calculated on the basis of the DVH of the whole treatment. Then the above assessment results were compared. Results: There were marked differ-ences between the assessment results derived from the plus of assessment parameters in treatment plan A and B, and the ones derived from treatment plan F. Conclusion: When a treatment plan is altered during the course of radiation treatment, image fusion technique should be performed in the establishment of a new one. The estimation of the assessment parameters for the whole treatment with treatment plan A and B by simple plus, is inaccurate.展开更多
Traditional hourly rain gauges and automatic weather stations rarely measure solid precipitation, except for those stations with weighing-type precipitation sensors. Microwave remote sensing has only a low ability to ...Traditional hourly rain gauges and automatic weather stations rarely measure solid precipitation, except for those stations with weighing-type precipitation sensors. Microwave remote sensing has only a low ability to retrieve solid precipitation. In addition, there are no long-term, high-quality precipitation data in China that can be used to drive land surface models. To address these issues, in the China Meteorological Administration(CMA) Land Data Assimilation System(CLDAS), we blended the Climate Prediction Center(CPC) morphing technique(CMORPH) and Modern-Era Retrospective analysis for Research and Applications version 2(MERRA2) precipitation datasets with observed temperature and precipitation data on various temporal scales using multigrid variational analysis and temporal downscaling to produce a multi-source precipitation fusion dataset for China(CLDAS-Prcp). This dataset covers all of China at a resolution of 6.25 km at hourly intervals from 1998 to 2018. We performed dependent and independent evaluations of the CLDAS-Prcp dataset from the perspectives of seasonal total precipitation and land surface model simulation. Our results show that the CLDAS-Prcp dataset represents reasonably the spatial distribution of precipitation in China. The dependent evaluation indicates that the CLDAS-Prcp performs better than the MERRA2 precipitation, CMORPH precipitation, Global Land Data Assimilation System version 2(GLDAS-V2.1) precipitation,and CLDAS-V2.0 winter precipitation, as compared to the meteorological observational precipitation. The independent evaluation indicates that the CLDAS-Prcp dataset performs better than the Global Precipitation Measurement(GPM) precipitation dataset and is similar to the CLDAS-V2.0 summer precipitation dataset based on the hydrological observational precipitation. The simulated soil moisture content driven by CLDAS-Prcp is slightly better than that driven by the CLDAS-V2.0 precipitation, whereas the snow depth simulation driven by CLDAS-Prcp is much better than that driven by the展开更多
多源信息融合技术是20世纪发展的高新技术,关于多源信息融合,目前还没有形成一个统一的概念,其基本概念和融合模型仍以美国国防部数据融合联合指挥实验室(Joint Directors of Laboratories)提出的内容为标准。信息融合的算法还没有形成...多源信息融合技术是20世纪发展的高新技术,关于多源信息融合,目前还没有形成一个统一的概念,其基本概念和融合模型仍以美国国防部数据融合联合指挥实验室(Joint Directors of Laboratories)提出的内容为标准。信息融合的算法还没有形成固定的模式,大多数领域专家提出的算法具有局限性。信息融合的应用主要表现在军事方面,近年逐步延伸到民用领域。展开更多
Background: Minimally invasive transforaminal lumbar interbody fusion (MI TLIF) is a widely known and performed technique, however its versatility among different physicians continues to hinder its replication and res...Background: Minimally invasive transforaminal lumbar interbody fusion (MI TLIF) is a widely known and performed technique, however its versatility among different physicians continues to hinder its replication and results. Therefore, this study aimed to provide a step-by-step surgical guide to perform a safe MI-TLIF, based on the results obtained in patients operated on by a single surgeon over a period of 12 years. Patients and methods: A retrospective, single center, longitudinal, and observational cohort study was conducted with 931 patients who underwent MI TLIF by a single surgeon between 2010 and 2022 using the technique described on this paper, each with a minimum follow-up of 12 months. Criteria included Schizas classification, listhesis according to Meyerding classification, number of levels treated, cage size, and complications (screw repositioning or cerebrospinal fluid leak). Patient clinical outcomes were assessed using the Oswestry Disability Index (ODI), Visual Analog Scale (VAS) for pre- and postoperative radicular pain. Thin slice CT scans were used to assess the progression of the fusion using the Bridwell classification. In the statistical analysis, percentages, median, and interquartile range (IQR) were calculated. Results: Nine hundred and thirty one patients underwent MI TLIF using the technique described, eight hundred and eighty (94.5%) had a single level treated and fifty one (5.5%) had a 2 level procedure (982 levels), an 8mm cage was placed on five hundred and seventeenlevels (52.7%), six hundred and sixty three levels(67.6%) achieved grade I fusion, two hundred and sixty six levels (27.1%) achieved grade II fusion, 52 levels (5.3) achieved grade III fusion and one level (0.1) achieved a grade IV fusion or non-union. Revision surgery was performed on 3 patients (0.3%) for screw repositioning, cerebrospinal fluid leak was present on 2 patients during surgery and treated before closure. VAS scores and ODI were improved at 12 months postop (VAS from 8.70 to 2.30 and ODI from 34.2 to 14.1, 展开更多
基金a grant from the Key Program of Science and Technology Foundation of Hubei Province (No. 2007A301B33).
文摘Objective: We studied the application of CT image fusion in the evaluation of radiation treatment planning for non-small cell lung cancer (NSCLC). Methods: Eleven patients with NSCLC, who were treated with three-dimensional con-formal radiation therapy, were studied. Each patient underwent twice sequential planning CT scan, i.e., at pre-treatment, and at mid-treatment for field reduction planning. Three treatment plans were established in each patient: treatment plan A was based on the pre-treatment planning CT scans for the first course of treatment, plan B on the mid-treatment planning CT scans for the second course of treatment, and treatment plan F on the fused images for the whole treatment. The irradiation doses received by organs at risk in the whole treatment with treatment A and B plans were estimated by the plus of the parameters in treatment plan A and B, assuming that the parameters involve the different tissues (i.e. V20=AV20+BV20), or the same tissues within an organ (i.e. Dmax=ADmax+BDmax). The assessment parameters in the treatment plan F were calculated on the basis of the DVH of the whole treatment. Then the above assessment results were compared. Results: There were marked differ-ences between the assessment results derived from the plus of assessment parameters in treatment plan A and B, and the ones derived from treatment plan F. Conclusion: When a treatment plan is altered during the course of radiation treatment, image fusion technique should be performed in the establishment of a new one. The estimation of the assessment parameters for the whole treatment with treatment plan A and B by simple plus, is inaccurate.
基金Supported by the National Key Research and Development Program of China(2018YFC1506601)National Natural Science Foundation of China(91437220)+1 种基金China Meteorological Administration Special Public Welfare Research Fund(GYHY201506002 and GYHY201206008)China Meteorological Administration“Meteorological Data Quality Control and Multi-source Data Fusion and Reanalysis”project。
文摘Traditional hourly rain gauges and automatic weather stations rarely measure solid precipitation, except for those stations with weighing-type precipitation sensors. Microwave remote sensing has only a low ability to retrieve solid precipitation. In addition, there are no long-term, high-quality precipitation data in China that can be used to drive land surface models. To address these issues, in the China Meteorological Administration(CMA) Land Data Assimilation System(CLDAS), we blended the Climate Prediction Center(CPC) morphing technique(CMORPH) and Modern-Era Retrospective analysis for Research and Applications version 2(MERRA2) precipitation datasets with observed temperature and precipitation data on various temporal scales using multigrid variational analysis and temporal downscaling to produce a multi-source precipitation fusion dataset for China(CLDAS-Prcp). This dataset covers all of China at a resolution of 6.25 km at hourly intervals from 1998 to 2018. We performed dependent and independent evaluations of the CLDAS-Prcp dataset from the perspectives of seasonal total precipitation and land surface model simulation. Our results show that the CLDAS-Prcp dataset represents reasonably the spatial distribution of precipitation in China. The dependent evaluation indicates that the CLDAS-Prcp performs better than the MERRA2 precipitation, CMORPH precipitation, Global Land Data Assimilation System version 2(GLDAS-V2.1) precipitation,and CLDAS-V2.0 winter precipitation, as compared to the meteorological observational precipitation. The independent evaluation indicates that the CLDAS-Prcp dataset performs better than the Global Precipitation Measurement(GPM) precipitation dataset and is similar to the CLDAS-V2.0 summer precipitation dataset based on the hydrological observational precipitation. The simulated soil moisture content driven by CLDAS-Prcp is slightly better than that driven by the CLDAS-V2.0 precipitation, whereas the snow depth simulation driven by CLDAS-Prcp is much better than that driven by the
文摘多源信息融合技术是20世纪发展的高新技术,关于多源信息融合,目前还没有形成一个统一的概念,其基本概念和融合模型仍以美国国防部数据融合联合指挥实验室(Joint Directors of Laboratories)提出的内容为标准。信息融合的算法还没有形成固定的模式,大多数领域专家提出的算法具有局限性。信息融合的应用主要表现在军事方面,近年逐步延伸到民用领域。
文摘Background: Minimally invasive transforaminal lumbar interbody fusion (MI TLIF) is a widely known and performed technique, however its versatility among different physicians continues to hinder its replication and results. Therefore, this study aimed to provide a step-by-step surgical guide to perform a safe MI-TLIF, based on the results obtained in patients operated on by a single surgeon over a period of 12 years. Patients and methods: A retrospective, single center, longitudinal, and observational cohort study was conducted with 931 patients who underwent MI TLIF by a single surgeon between 2010 and 2022 using the technique described on this paper, each with a minimum follow-up of 12 months. Criteria included Schizas classification, listhesis according to Meyerding classification, number of levels treated, cage size, and complications (screw repositioning or cerebrospinal fluid leak). Patient clinical outcomes were assessed using the Oswestry Disability Index (ODI), Visual Analog Scale (VAS) for pre- and postoperative radicular pain. Thin slice CT scans were used to assess the progression of the fusion using the Bridwell classification. In the statistical analysis, percentages, median, and interquartile range (IQR) were calculated. Results: Nine hundred and thirty one patients underwent MI TLIF using the technique described, eight hundred and eighty (94.5%) had a single level treated and fifty one (5.5%) had a 2 level procedure (982 levels), an 8mm cage was placed on five hundred and seventeenlevels (52.7%), six hundred and sixty three levels(67.6%) achieved grade I fusion, two hundred and sixty six levels (27.1%) achieved grade II fusion, 52 levels (5.3) achieved grade III fusion and one level (0.1) achieved a grade IV fusion or non-union. Revision surgery was performed on 3 patients (0.3%) for screw repositioning, cerebrospinal fluid leak was present on 2 patients during surgery and treated before closure. VAS scores and ODI were improved at 12 months postop (VAS from 8.70 to 2.30 and ODI from 34.2 to 14.1,
