AIM:To compare the fast-track rehabilitation program and conventional care for patients after resection of colorectal cancer.METHODS:One hundred and six consecutive patients who underwent fast-track rehabilitation pro...AIM:To compare the fast-track rehabilitation program and conventional care for patients after resection of colorectal cancer.METHODS:One hundred and six consecutive patients who underwent fast-track rehabilitation program were encouraged to have early oral feeding and movement for early discharge,while 104 consecutive patients underwent conventional care after resection of colorectal cancer.Their gastrointestinal functions,postoperative complications and hospital stay time were recorded.RESULTS:The restoration time of gastrointestinal functions in the patients was significantly faster after fasttrack rehabilitation program than after conventional care(2.1 d vs 3.2 d,P < 0.01).The percentage of patients who developed complications was significantly lower 30 d after fast-track rehabilitation program than after conventional care(13.2% vs 26.9%,P < 0.05).Also,the percentage of patients who had general complications was significantly lower 30 d after fast-track rehabilitation program than after conventional care(6.6% vs 15.4%,P < 0.05).The postoperative hospital stay time of the patients was shorter after fast-track rehabilitation program than after conventional care(5 d vs 7 d,P < 0.01).No significant difference was observed in the readmission rate 30 d after fast-track rehabilitation program and conventional care(3.8% vs 8.7%).CONCLUSION:The fast-track rehabilitation program can significantly decrease the complications and shorten the time of postoperative hospital stay of patients after resection colorectal cancer.展开更多
A fast version of the State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics （LASG）/Institute of Atmospheric Physics （IAP） climate system model is briefly documented. Th...A fast version of the State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics （LASG）/Institute of Atmospheric Physics （IAP） climate system model is briefly documented. The fast coupled model employs a low resolution version of the atmospheric component Grid Atmospheric Model of IAP/LASG （GAMIL）, with the other parts of the model, namely an oceanic component LASG/IAP Climate Ocean Model （LICOM）, land component Common Land Model （CLM）, and sea ice component from National Center for Atmospheric Research Community Climate System Model （NCAR CCSM2）, as the same as in the standard version of LASG/IAP Flexible Global Ocean Atmosphere Land System model （FGOALS_g）. The parameterizations of physical and dynamical processes of the atmospheric component in the fast version are identical to the standard version, although some parameter values are different. However, by virtue of reduced horizontal resolution and increased time-step of the most time-consuming atmospheric component, it runs faster by a factor of 3 and can serve as a useful tool for longterm and large-ensemble integrations. A 1000-year control simulation of the present-day climate has been completed without flux adjustments. The final 600 years of this simulation has virtually no trends in global mean sea surface temperatures and is recommended for internal variability studies. Several aspects of the control simulation＇s mean climate and variability are evaluated against the observational or reanalysis data. The strengths and weaknesses of the control simulation are evaluated. The mean atmospheric circulation is well simulated, except in high latitudes. The Asian-Australian monsoonal meridional cell shows realistic features, however, an artificial rainfall center is located to the eastern periphery of the Tibetan Plateau persists throughout the year. The mean bias of SST resembles that of the standard version, appearing as a ＂double ITCZ＂ （Inter-Tropical Convergence Zone） associated展开更多
We analyzed 360 permanent and campaign GPS data from 1999 to 2017 in the southern Sichuan-Yunan block, and obtained crustal horizontal deformation in this region.Then, we derived the strain rate using a multi-scale sp...We analyzed 360 permanent and campaign GPS data from 1999 to 2017 in the southern Sichuan-Yunan block, and obtained crustal horizontal deformation in this region.Then, we derived the strain rate using a multi-scale spherical wavelet method.Results reveal a complex pattern of tectonic movement in the southern Sichuan-Yunnan block.Compared to the stable Eurasian plate, the maximum rate of the horizontal deformation in the southern Sichuan-Yunnan block is approximately 22 mm/a.The Xiaojiang fault shows a significantly lower deformation—a left-lateral strike-slip movement of 9.5 mm/a.The Honghe fault clearly shows a complex segmental deformation from the north to south.The northern Honghe fault shows 4.3 mm/a right strike-slip with 6.7 mm/a extension; the southern Honghe fault shows 1.9 mm/a right strike-slip with 1.9 mm/a extension; the junction zone in the Honghe and Lijiang–Xiaojinhe faults shows an obvious clockwise-rotation deformation.The strain calculation results reveal that the maximum shear-strain rate in this region reaches 70 nstrain/a, concentrated around the Xiaojiang fault and at the junction of the Honghe and Lijiang–Xiaojinhe faults.We note that most of the earthquakes with magnitudes of 4 and above that occurred in this region were within the high shear strain-rate zones and the strain rate gradient boundary zone, which indicates that the magnitude of strain accumulation is closely related to the seismic activities.Comparison of the fast shear-wave polarization direction of the upper-crust with the upper-mantle anisotropy and the direction of the surface principal compressive strain rate obtained from the inversion of the GPS data reveals that the direction of the surface principal compressive strain is basically consistent with the fast shear-wave polarization direction of the upper crust anisotropy, but different from the polarization direction of the upper mantle.Our results support the hypothesis that the principal elements of the deformation mechanism in the southern Sichuan-Yunnan block 展开更多
通过采用硫酸铵盐析法、DEAE-Sepharose Fast Flow离子交换层析法提取分离制备苦荞水溶性蛋白,并通过磷酸盐缓冲液pH值、动态层析流速的最佳选择改善分离提纯效果。同时通过体外吸附胆酸盐能力的测定证实所提取分离得到的苦荞水溶性蛋...通过采用硫酸铵盐析法、DEAE-Sepharose Fast Flow离子交换层析法提取分离制备苦荞水溶性蛋白,并通过磷酸盐缓冲液pH值、动态层析流速的最佳选择改善分离提纯效果。同时通过体外吸附胆酸盐能力的测定证实所提取分离得到的苦荞水溶性蛋白具有一定的降血脂功能。结果发现:当磷酸盐缓冲溶液pH值为6.5、流速1.0mL/min于室温下洗脱的效果最好,得到的3个主要分离组分中峰3的体外吸附胆酸盐能力最佳。展开更多
基金Supported by Social Development Fund of Jiangsu Province,No. BS2007054
文摘AIM:To compare the fast-track rehabilitation program and conventional care for patients after resection of colorectal cancer.METHODS:One hundred and six consecutive patients who underwent fast-track rehabilitation program were encouraged to have early oral feeding and movement for early discharge,while 104 consecutive patients underwent conventional care after resection of colorectal cancer.Their gastrointestinal functions,postoperative complications and hospital stay time were recorded.RESULTS:The restoration time of gastrointestinal functions in the patients was significantly faster after fasttrack rehabilitation program than after conventional care(2.1 d vs 3.2 d,P < 0.01).The percentage of patients who developed complications was significantly lower 30 d after fast-track rehabilitation program than after conventional care(13.2% vs 26.9%,P < 0.05).Also,the percentage of patients who had general complications was significantly lower 30 d after fast-track rehabilitation program than after conventional care(6.6% vs 15.4%,P < 0.05).The postoperative hospital stay time of the patients was shorter after fast-track rehabilitation program than after conventional care(5 d vs 7 d,P < 0.01).No significant difference was observed in the readmission rate 30 d after fast-track rehabilitation program and conventional care(3.8% vs 8.7%).CONCLUSION:The fast-track rehabilitation program can significantly decrease the complications and shorten the time of postoperative hospital stay of patients after resection colorectal cancer.
基金Acknowledgements. This work was jointly supported by the Chinese Academy of Sciences through the International Partnership Creative Group entitled ＂The Climate System Model Development and Application Studies＂, the Major State Basic Research Development Program of China （973 Program） under Grant No. 2005CB321703, and the National Natural Science Foundation of China （Grant Nos. 40675050, 40221503, 40625014）. The long-term integration of the coupled model was finished on the Lenovo DeepComp 6800 supercomputer at the Supercomputing Center of the Chinese Academy of Sciences, and the IBM SP690 at the Institute of Atmospheric Physics, Chinese Academy of Sciences. The authors appreciate the contribution of Drs. R. C. Yu, Y. Q. Yu, H. L. Liu, W. P. Zheng, J. Li, X. G Xin, and Mrs. H. Wan, H. M. Li in the model development and validations.
文摘A fast version of the State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics （LASG）/Institute of Atmospheric Physics （IAP） climate system model is briefly documented. The fast coupled model employs a low resolution version of the atmospheric component Grid Atmospheric Model of IAP/LASG （GAMIL）, with the other parts of the model, namely an oceanic component LASG/IAP Climate Ocean Model （LICOM）, land component Common Land Model （CLM）, and sea ice component from National Center for Atmospheric Research Community Climate System Model （NCAR CCSM2）, as the same as in the standard version of LASG/IAP Flexible Global Ocean Atmosphere Land System model （FGOALS_g）. The parameterizations of physical and dynamical processes of the atmospheric component in the fast version are identical to the standard version, although some parameter values are different. However, by virtue of reduced horizontal resolution and increased time-step of the most time-consuming atmospheric component, it runs faster by a factor of 3 and can serve as a useful tool for longterm and large-ensemble integrations. A 1000-year control simulation of the present-day climate has been completed without flux adjustments. The final 600 years of this simulation has virtually no trends in global mean sea surface temperatures and is recommended for internal variability studies. Several aspects of the control simulation＇s mean climate and variability are evaluated against the observational or reanalysis data. The strengths and weaknesses of the control simulation are evaluated. The mean atmospheric circulation is well simulated, except in high latitudes. The Asian-Australian monsoonal meridional cell shows realistic features, however, an artificial rainfall center is located to the eastern periphery of the Tibetan Plateau persists throughout the year. The mean bias of SST resembles that of the standard version, appearing as a ＂double ITCZ＂ （Inter-Tropical Convergence Zone） associated
基金supported by the National Natural Science Foundation of China (Project 41730212)the Basic Research Project of the Institute of Earthquake Forecasting, China Earthquake Administration (Grant No.2017IES0102, 2016IES0201)
文摘We analyzed 360 permanent and campaign GPS data from 1999 to 2017 in the southern Sichuan-Yunan block, and obtained crustal horizontal deformation in this region.Then, we derived the strain rate using a multi-scale spherical wavelet method.Results reveal a complex pattern of tectonic movement in the southern Sichuan-Yunnan block.Compared to the stable Eurasian plate, the maximum rate of the horizontal deformation in the southern Sichuan-Yunnan block is approximately 22 mm/a.The Xiaojiang fault shows a significantly lower deformation—a left-lateral strike-slip movement of 9.5 mm/a.The Honghe fault clearly shows a complex segmental deformation from the north to south.The northern Honghe fault shows 4.3 mm/a right strike-slip with 6.7 mm/a extension; the southern Honghe fault shows 1.9 mm/a right strike-slip with 1.9 mm/a extension; the junction zone in the Honghe and Lijiang–Xiaojinhe faults shows an obvious clockwise-rotation deformation.The strain calculation results reveal that the maximum shear-strain rate in this region reaches 70 nstrain/a, concentrated around the Xiaojiang fault and at the junction of the Honghe and Lijiang–Xiaojinhe faults.We note that most of the earthquakes with magnitudes of 4 and above that occurred in this region were within the high shear strain-rate zones and the strain rate gradient boundary zone, which indicates that the magnitude of strain accumulation is closely related to the seismic activities.Comparison of the fast shear-wave polarization direction of the upper-crust with the upper-mantle anisotropy and the direction of the surface principal compressive strain rate obtained from the inversion of the GPS data reveals that the direction of the surface principal compressive strain is basically consistent with the fast shear-wave polarization direction of the upper crust anisotropy, but different from the polarization direction of the upper mantle.Our results support the hypothesis that the principal elements of the deformation mechanism in the southern Sichuan-Yunnan block
文摘通过采用硫酸铵盐析法、DEAE-Sepharose Fast Flow离子交换层析法提取分离制备苦荞水溶性蛋白,并通过磷酸盐缓冲液pH值、动态层析流速的最佳选择改善分离提纯效果。同时通过体外吸附胆酸盐能力的测定证实所提取分离得到的苦荞水溶性蛋白具有一定的降血脂功能。结果发现:当磷酸盐缓冲溶液pH值为6.5、流速1.0mL/min于室温下洗脱的效果最好,得到的3个主要分离组分中峰3的体外吸附胆酸盐能力最佳。
