It has been almost 50 years since the term“brain–computer interface”(BCI)was first proposed by Jacques J.Vidal in 1973[1].Unlike traditional electronic interfaces that transmit nonliving information between devices...It has been almost 50 years since the term“brain–computer interface”(BCI)was first proposed by Jacques J.Vidal in 1973[1].Unlike traditional electronic interfaces that transmit nonliving information between devices,BCIs set up a communication bridge between a living brain and nonliving devices.Technically speaking,a BCI is a system that measures brain activity and converts it into the artificial outputs that replace,restore,enhance,supplement,or improve the natural central nervous system outputs[2].At present,electroencephalography(EEG)is the most commonly used brain signal for BCIs.展开更多
Genome editing based on CRISPR/Cas9 system enables unprecedented breakthroughs in genomic research and the engineering of variants associated to clinical diseases[1,2].The CRISPR/Cas9 system induces double strand brea...Genome editing based on CRISPR/Cas9 system enables unprecedented breakthroughs in genomic research and the engineering of variants associated to clinical diseases[1,2].The CRISPR/Cas9 system induces double strand breaks(DSBs),which are primarily repaired by non-homologous end joining(NHEJ)and low-efficiency homologydirect repair(HDR)pathways.However.展开更多
基金We appreciate the financial support from the National Key Research and Development Program of China(2017YFB1300300)the National Natural Science Foundation of China(62122059,81925020,61976152,and 81630051)the Young Elite Scientist Sponsorship Program by CAST(2018QNRC001).
文摘It has been almost 50 years since the term“brain–computer interface”(BCI)was first proposed by Jacques J.Vidal in 1973[1].Unlike traditional electronic interfaces that transmit nonliving information between devices,BCIs set up a communication bridge between a living brain and nonliving devices.Technically speaking,a BCI is a system that measures brain activity and converts it into the artificial outputs that replace,restore,enhance,supplement,or improve the natural central nervous system outputs[2].At present,electroencephalography(EEG)is the most commonly used brain signal for BCIs.
文摘Genome editing based on CRISPR/Cas9 system enables unprecedented breakthroughs in genomic research and the engineering of variants associated to clinical diseases[1,2].The CRISPR/Cas9 system induces double strand breaks(DSBs),which are primarily repaired by non-homologous end joining(NHEJ)and low-efficiency homologydirect repair(HDR)pathways.However.