The influence of ENSO on the summer climate change in China and its mechanism from the observed data is discussed. It is discovered that in the developing stage of ENSO, the SST in the western tropical Pacific is col... The influence of ENSO on the summer climate change in China and its mechanism from the observed data is discussed. It is discovered that in the developing stage of ENSO, the SST in the western tropical Pacific is colder in summer, the convective activities may be weak around the South China Sea and the Philippines. As a consequence, the subtropical high shifted southward. Therefore, a drought may be caused in the Indo-China peninsula and in the South China. Moreover, in midsummer the subtropical high is weak over the Yangtze River valley and Huaihe River valley, and the flood may be caused in the area from the Yangtze River valley to Huaihe River valley. On the contrary, in the decaying stage of ENSO. the convective activities may be strong around the Philippines, and the subtropical high shifted northward, a drought may be caused in the Yangtze River valley and Huaihe River valley.展开更多
Chinese medicine(CM) is usually prescribed as CM formula to treat disease. The lack of effective research approach makes it difficult to elucidate the molecular mechanisms of CM formula owing to its complicated chemic...Chinese medicine(CM) is usually prescribed as CM formula to treat disease. The lack of effective research approach makes it difficult to elucidate the molecular mechanisms of CM formula owing to its complicated chemical compounds. Network pharmacology is increasingly applied in CM formula research in recent years, which is identified suitable for the study of CM formula. In this review, we summarized the methodology of network pharmacology, including network construction, network analysis and network verification. The aim of constructing a network is to achieve the interaction between the bioactive compounds and targets and the interaction between various targets, and then find out and validate the key nodes via network analysis and network verification. Besides, we reviewed the application in CM formula research, mainly including targets discovery, bioactive compounds screening, toxicity evaluation, mechanism research and quality control research. Finally, we proposed prospective in the future and limitations of network pharmacology, expecting to provide new strategy and thinking on study for CM formula.展开更多
本文以"resilient""resilience""city""urban"作为四个关键词进行组合,运用web of science搜索平台(包括SCI、SSCI等引文数据库),对2000—2015年在国际主要杂志,如《城市》《景观与城市规划》...本文以"resilient""resilience""city""urban"作为四个关键词进行组合,运用web of science搜索平台(包括SCI、SSCI等引文数据库),对2000—2015年在国际主要杂志,如《城市》《景观与城市规划》《环境与城市化》等上发表的论文进行检索,加上相关经典著作、会议报告等,共收集约120份文献资料,基于此详细分析了韧性城市理论演变以及研究的主要内容。韧性的概念最早出现自1970年代的生态学,经历了从"平衡性"到"适应性"的演变,目前主要应用于灾害和气候变化、城市和区域经济韧性、城市基础设施韧性、城市恐怖袭击韧性、空间和城市规划等领域。其研究的内容主要集中在韧性城市演化机理、韧性城市评价、韧性城市规划等方面。展开更多
文摘 The influence of ENSO on the summer climate change in China and its mechanism from the observed data is discussed. It is discovered that in the developing stage of ENSO, the SST in the western tropical Pacific is colder in summer, the convective activities may be weak around the South China Sea and the Philippines. As a consequence, the subtropical high shifted southward. Therefore, a drought may be caused in the Indo-China peninsula and in the South China. Moreover, in midsummer the subtropical high is weak over the Yangtze River valley and Huaihe River valley, and the flood may be caused in the area from the Yangtze River valley to Huaihe River valley. On the contrary, in the decaying stage of ENSO. the convective activities may be strong around the Philippines, and the subtropical high shifted northward, a drought may be caused in the Yangtze River valley and Huaihe River valley.
基金Supported by the National Natural Science Foundation of China(No.81530102)Guangdong Provincial Science and Technology Agency Special Funds(No.2017B050504005)Guangzhou City Science and Technology Agency Special Funds(No.201803010069)
文摘Chinese medicine(CM) is usually prescribed as CM formula to treat disease. The lack of effective research approach makes it difficult to elucidate the molecular mechanisms of CM formula owing to its complicated chemical compounds. Network pharmacology is increasingly applied in CM formula research in recent years, which is identified suitable for the study of CM formula. In this review, we summarized the methodology of network pharmacology, including network construction, network analysis and network verification. The aim of constructing a network is to achieve the interaction between the bioactive compounds and targets and the interaction between various targets, and then find out and validate the key nodes via network analysis and network verification. Besides, we reviewed the application in CM formula research, mainly including targets discovery, bioactive compounds screening, toxicity evaluation, mechanism research and quality control research. Finally, we proposed prospective in the future and limitations of network pharmacology, expecting to provide new strategy and thinking on study for CM formula.
文摘本文以"resilient""resilience""city""urban"作为四个关键词进行组合,运用web of science搜索平台(包括SCI、SSCI等引文数据库),对2000—2015年在国际主要杂志,如《城市》《景观与城市规划》《环境与城市化》等上发表的论文进行检索,加上相关经典著作、会议报告等,共收集约120份文献资料,基于此详细分析了韧性城市理论演变以及研究的主要内容。韧性的概念最早出现自1970年代的生态学,经历了从"平衡性"到"适应性"的演变,目前主要应用于灾害和气候变化、城市和区域经济韧性、城市基础设施韧性、城市恐怖袭击韧性、空间和城市规划等领域。其研究的内容主要集中在韧性城市演化机理、韧性城市评价、韧性城市规划等方面。
