INTRODUCTION Conceivably the presence of basement membrane(BM)in a neoplasm might be a result of interactionof tumor cells with the extracellular matrix.Collagen Ⅳ is one of the major intrinsic componentsof BM.Recent...INTRODUCTION Conceivably the presence of basement membrane(BM)in a neoplasm might be a result of interactionof tumor cells with the extracellular matrix.Collagen Ⅳ is one of the major intrinsic componentsof BM.Recent study has shown that collagen Ⅳhas cell adhesion function and is involved in theprocess of tumor invasion and metastasis,includingcolorectal cancer and breast cancer.But there arefew systematic studies on gastric cancer and theresults are equivocal.In this study we evaluated展开更多
基金National Clinical Major Program of Ministry of Public Health,No.97100250
文摘INTRODUCTION Conceivably the presence of basement membrane(BM)in a neoplasm might be a result of interactionof tumor cells with the extracellular matrix.Collagen Ⅳ is one of the major intrinsic componentsof BM.Recent study has shown that collagen Ⅳhas cell adhesion function and is involved in theprocess of tumor invasion and metastasis,includingcolorectal cancer and breast cancer.But there arefew systematic studies on gastric cancer and theresults are equivocal.In this study we evaluated