目的:评估原发性闭角型青光眼(primary angle-closure glaucoma,PACG)患者的心理和视觉健康相关生存质量状况,分析青光眼小梁切除手术对其影响。方法:采用前瞻性随机临床对照的方法,对42例PACG患者分别采用国家眼科研究视功能问卷(25-it...目的:评估原发性闭角型青光眼(primary angle-closure glaucoma,PACG)患者的心理和视觉健康相关生存质量状况,分析青光眼小梁切除手术对其影响。方法:采用前瞻性随机临床对照的方法,对42例PACG患者分别采用国家眼科研究视功能问卷(25-item national eye institute visual functioning questionnaire,NEI-VFQ-25)和综合医院焦虑抑郁量表(hospital anxiety and depression scale,HADS)中文版评定患者最近1mo的视觉生活质量和焦虑、抑郁评分,术后1mo再次患者评定焦虑、抑郁情况及视觉生活质量,42例健康自愿者作为对照,分析其心理和视觉健康相关生存质量变化情况。结果:PACG患者焦虑、抑郁及共患患者发生率分别为23.8%,23.8%和16.7%。NEI-VFQ-25评分显示患者在视觉健康相关生存质量部分亚功能(10/12)如一般健康、总体视觉、社会功能、心理问题、周边视野和依赖性等均有不同程度的损害(P<0.05)。通过小梁切除手术干预,患者焦虑、抑郁评分明显好转(P<0.05),视觉健康相关生存质量的样本中位数差值[41.6(一般健康)、34.5(眼痛)、32.6(社会功能)、21.2(心理问题)、24.8(社会活动)、21.8(依赖性)],均较手术前明显改善[10.4(一般健康)、6.4(眼痛)、10.6(社会功能)、8.3(心理问题)、7.3(社会活动)、6.9(依赖性);均为P<0.05]。结论:PACG患者焦虑、抑郁状况加重,视觉健康相关生存质量明显降低。小梁切除术有助于患者视觉生活质量和心理康复。展开更多
BACKGROUND Psychological assessment after intensive care unit(ICU)discharge is increasingly used to assess patients'cognitive and psychological well-being.However,few studies have examined those who recovered from...BACKGROUND Psychological assessment after intensive care unit(ICU)discharge is increasingly used to assess patients'cognitive and psychological well-being.However,few studies have examined those who recovered from coronavirus disease 2019(COVID-19).There is a paucity of data from the Middle East assessing the post-ICU discharge mental health status of patients who had COVID-19.AIM To evaluate anxiety and depression among patients who had severe COVID-19.METHODS This is a prospective single-center follow-up questionnaire-based study of adults who were admitted to the ICU or under ICU consultation for>24 h for COVID-19.Eligible patients were contacted via telephone.The patient’s anxiety and depression six months after ICU discharge were assessed using the Hospital Anxiety and Depression Scale(HADS).The primary outcome was the mean HADS score.The secondary outcomes were risk factors of anxiety and/or depression.RESULTS Patients who were admitted to the ICU because of COVID-19 were screened(n=518).Of these,48 completed the questionnaires.The mean age was 56.3±17.2 years.Thirty patients(62.5%)were male.The main comorbidities were endocrine(n=24,50%)and cardiovascular(n=21,43.8%)diseases.The mean overall HADS score for anxiety and depression at 6 months post-ICU discharge was 11.4(SD±8.5).A HADS score of>7 for anxiety and depression was detected in 15 patients(30%)and 18 patients(36%),respectively.Results from the multivariable ordered logistic regression demonstrated that vasopressor use was associated with the development of anxiety and depression[odds ratio(OR)39.06,95% confidence interval:1.309-1165.8;P<0.05].CONCLUSION Six months after ICU discharge,30% of patients who had COVID-19 demonstrated a HADS score that confirmed anxiety and depression.To compare the psychological status of patients following an ICU admission(with vs without COVID-19),further studies are warranted.展开更多
文摘目的研究原发性干燥综合征(primary Sjgren's syndrome,p SS)患者生活质量及焦虑抑郁情况并分析其影响因素。方法筛选309例p SS患者(男性5例,女性304例)作为研究对象,应用健康状况调查问卷(SF-36)评估患者生活质量,医院焦虑抑郁量表(HADS)评估患者焦虑抑郁情况。结果 p SS患者的SF-36各维度积分明显低于普通人群,HADS量表焦虑评分(HAS)、抑郁评分(HDS)均高于内科就诊人群(女性患者)(P<0.05)。进一步对女性p SS患者分析显示,疼痛评分、疲劳乏力评分与SF-36生理健康领域得分下降有关;疲劳乏力评分与心理健康领域得分下降有关。疼痛评分、疲劳乏力评分与HAS和HDS评分升高均有关。年龄的增长与HAS评分下降有关,皮肤干燥评分与HDS评分升高有关。结论 p SS患者的生活质量较普通人群明显下降,且具有明显的焦虑抑郁情绪。疼痛、疲劳乏力是影响生活质量和焦虑抑郁情绪的主要因素。
文摘目的:评估原发性闭角型青光眼(primary angle-closure glaucoma,PACG)患者的心理和视觉健康相关生存质量状况,分析青光眼小梁切除手术对其影响。方法:采用前瞻性随机临床对照的方法,对42例PACG患者分别采用国家眼科研究视功能问卷(25-item national eye institute visual functioning questionnaire,NEI-VFQ-25)和综合医院焦虑抑郁量表(hospital anxiety and depression scale,HADS)中文版评定患者最近1mo的视觉生活质量和焦虑、抑郁评分,术后1mo再次患者评定焦虑、抑郁情况及视觉生活质量,42例健康自愿者作为对照,分析其心理和视觉健康相关生存质量变化情况。结果:PACG患者焦虑、抑郁及共患患者发生率分别为23.8%,23.8%和16.7%。NEI-VFQ-25评分显示患者在视觉健康相关生存质量部分亚功能(10/12)如一般健康、总体视觉、社会功能、心理问题、周边视野和依赖性等均有不同程度的损害(P<0.05)。通过小梁切除手术干预,患者焦虑、抑郁评分明显好转(P<0.05),视觉健康相关生存质量的样本中位数差值[41.6(一般健康)、34.5(眼痛)、32.6(社会功能)、21.2(心理问题)、24.8(社会活动)、21.8(依赖性)],均较手术前明显改善[10.4(一般健康)、6.4(眼痛)、10.6(社会功能)、8.3(心理问题)、7.3(社会活动)、6.9(依赖性);均为P<0.05]。结论:PACG患者焦虑、抑郁状况加重,视觉健康相关生存质量明显降低。小梁切除术有助于患者视觉生活质量和心理康复。
基金the Researchers Supporting Project number,King Saud University,Riyadh,Saudi Arabia,No.RSPD2024R919.
文摘BACKGROUND Psychological assessment after intensive care unit(ICU)discharge is increasingly used to assess patients'cognitive and psychological well-being.However,few studies have examined those who recovered from coronavirus disease 2019(COVID-19).There is a paucity of data from the Middle East assessing the post-ICU discharge mental health status of patients who had COVID-19.AIM To evaluate anxiety and depression among patients who had severe COVID-19.METHODS This is a prospective single-center follow-up questionnaire-based study of adults who were admitted to the ICU or under ICU consultation for>24 h for COVID-19.Eligible patients were contacted via telephone.The patient’s anxiety and depression six months after ICU discharge were assessed using the Hospital Anxiety and Depression Scale(HADS).The primary outcome was the mean HADS score.The secondary outcomes were risk factors of anxiety and/or depression.RESULTS Patients who were admitted to the ICU because of COVID-19 were screened(n=518).Of these,48 completed the questionnaires.The mean age was 56.3±17.2 years.Thirty patients(62.5%)were male.The main comorbidities were endocrine(n=24,50%)and cardiovascular(n=21,43.8%)diseases.The mean overall HADS score for anxiety and depression at 6 months post-ICU discharge was 11.4(SD±8.5).A HADS score of>7 for anxiety and depression was detected in 15 patients(30%)and 18 patients(36%),respectively.Results from the multivariable ordered logistic regression demonstrated that vasopressor use was associated with the development of anxiety and depression[odds ratio(OR)39.06,95% confidence interval:1.309-1165.8;P<0.05].CONCLUSION Six months after ICU discharge,30% of patients who had COVID-19 demonstrated a HADS score that confirmed anxiety and depression.To compare the psychological status of patients following an ICU admission(with vs without COVID-19),further studies are warranted.
