目的:系统评价健脾益气化瘀解毒法(JPHYJD法)治疗慢性萎缩性胃炎(CAG)伴胃癌前病变(GPL)的疗效及安全性。方法:计算机检索国内外相关数据库,查找JPHYJD法治疗CAG-GLP的随机对照试验相关文献,采用Rev Man 5.3软件进行Meta分析。结果:共...目的:系统评价健脾益气化瘀解毒法(JPHYJD法)治疗慢性萎缩性胃炎(CAG)伴胃癌前病变(GPL)的疗效及安全性。方法:计算机检索国内外相关数据库,查找JPHYJD法治疗CAG-GLP的随机对照试验相关文献,采用Rev Man 5.3软件进行Meta分析。结果:共纳入合格文献32篇,共2 662例患者。Meta分析结果:JPHYJD法治疗CAG-GLP临床疗效方面、胃镜疗效、抗Hp有效率等方面优于单纯应用西药常规治疗,其差异均有统计学意义(P<0.00001);在改善胃痛、痞满、纳差、恶心、嗳气及安全性方面,JPHYJD法疗效亦优于西药常规治疗。结论:现有相关数据表明,JPHYJD法治疗CAG-GLP较单纯应用西药治疗临床疗效更好,胃镜疗效显著,能更有效抗Hp治疗,由于本Meta分析纳入研究较少,证据强度有限,上述结论仍需更多高质量研究加以验证。展开更多
Most quadruped reptiles, such as lizards, salamanders and crocodiles, swing their waists while climbing on horizontal or vertical surfaces. Accompanied by body movement, the centroid trajectory also becomes more of a ...Most quadruped reptiles, such as lizards, salamanders and crocodiles, swing their waists while climbing on horizontal or vertical surfaces. Accompanied by body movement, the centroid trajectory also becomes more of a zigzag path rather than a straight line. Inspired by gecko＇s gait and posture on a vertical surface, a gecko inspired model with one pendular waist and four active axil legs, which is called GPL model, is proposed. Relationship between the waist position, dynamic gait, and driving forces on supporting feet is analyzed. As for waist trajectory planning, a singular line between the supporting feet is found and its effects on driving forces are discussed. Based on the GPL model, it is found that a sinusoidal waist trajectory, rather than a straight line, makes the driving forces on the supporting legs smaller. Also, a waist close to the pygal can reduce the driving forces compared to the one near middle vertebration, which is in accord with gecko＇s body bending in the process of climbing. The principles of configuration design and gait planning are proposed based on theoretical analyses. Finally, a bio-inspired robot DracoBot is developed and both of the driving force measurements and climbing experiments reinforce theoretical analysis and the rationality of gecko＇s dynamic gait.展开更多
An analytical approach is proposed to study the postbuckling of circular cylindrical shells subject to axial compression and lateral pressure made of functionally graded graphene platelet-reinforced polymer composite ...An analytical approach is proposed to study the postbuckling of circular cylindrical shells subject to axial compression and lateral pressure made of functionally graded graphene platelet-reinforced polymer composite (FG-GPL-RPC). The governing equations are obtained in the context of the classical Donnell shell theory by the von K′arm′an nonlinear relations. Then, based on the Ritz energy method, an analytical solution approach is used to trace the nonlinear postbuckling path of the shell. The effects of several parameters such as the weight fraction of the graphene platelet (GPL), the geometrical properties, and distribution patterns of the GPL on the postbuckling characteristics of the FG-GPL-RPC shell are analyzed.展开更多
The aim of this paper is to set up an efficient nonlinear application algorithm predictive model for a multi aircraft landing dynamic system called “Aircraft Landing Dynamic System, Release 2019<em>A</em>...The aim of this paper is to set up an efficient nonlinear application algorithm predictive model for a multi aircraft landing dynamic system called “Aircraft Landing Dynamic System, Release 2019<em>A</em><sup>+</sup> version “<em>AIRLADYS R</em>2019<em>A</em><sup>+</sup>”. This programming software combines dynamic programming technic for mathematical computing and optimisation run under AMPL and KNITRO Solver. It uses also a descriptive programming technic for software design. The user interfaces designed in Glade are saved as XML, and by using the GtkBuilder GTK+ object these can be loaded by applications dynamically as needed. By using GtkBuilder, Glade XML files can be used in numerous programming languages including C, C++, C#, Java, Perl, Python, AMPL, etc. Glade is Free Software released under the GNU GPL License. By these tools, the solved problem is a mathematical modelization problem as a non-convex optimal control governed by ordinary non-linear differential equations. The dynamic programming technic is applied because it is a sufficiently high order and it does not require computation of the partial derivatives of the aircraft dynamic. This application will be coded with Linux system on 64 bit operating system, but it can also be run on the windows system. High running performances are obtained with results giving feasible trajectories with a robust optimizing of the objective function.展开更多
文摘目的:系统评价健脾益气化瘀解毒法(JPHYJD法)治疗慢性萎缩性胃炎(CAG)伴胃癌前病变(GPL)的疗效及安全性。方法:计算机检索国内外相关数据库,查找JPHYJD法治疗CAG-GLP的随机对照试验相关文献,采用Rev Man 5.3软件进行Meta分析。结果:共纳入合格文献32篇,共2 662例患者。Meta分析结果:JPHYJD法治疗CAG-GLP临床疗效方面、胃镜疗效、抗Hp有效率等方面优于单纯应用西药常规治疗,其差异均有统计学意义(P<0.00001);在改善胃痛、痞满、纳差、恶心、嗳气及安全性方面,JPHYJD法疗效亦优于西药常规治疗。结论:现有相关数据表明,JPHYJD法治疗CAG-GLP较单纯应用西药治疗临床疗效更好,胃镜疗效显著,能更有效抗Hp治疗,由于本Meta分析纳入研究较少,证据强度有限,上述结论仍需更多高质量研究加以验证。
基金This work was supported by the National Natural Science Foundation of China （No. 51475018） and Beijing Natural Science Foundation （No. 3162018）.
文摘Most quadruped reptiles, such as lizards, salamanders and crocodiles, swing their waists while climbing on horizontal or vertical surfaces. Accompanied by body movement, the centroid trajectory also becomes more of a zigzag path rather than a straight line. Inspired by gecko＇s gait and posture on a vertical surface, a gecko inspired model with one pendular waist and four active axil legs, which is called GPL model, is proposed. Relationship between the waist position, dynamic gait, and driving forces on supporting feet is analyzed. As for waist trajectory planning, a singular line between the supporting feet is found and its effects on driving forces are discussed. Based on the GPL model, it is found that a sinusoidal waist trajectory, rather than a straight line, makes the driving forces on the supporting legs smaller. Also, a waist close to the pygal can reduce the driving forces compared to the one near middle vertebration, which is in accord with gecko＇s body bending in the process of climbing. The principles of configuration design and gait planning are proposed based on theoretical analyses. Finally, a bio-inspired robot DracoBot is developed and both of the driving force measurements and climbing experiments reinforce theoretical analysis and the rationality of gecko＇s dynamic gait.
文摘An analytical approach is proposed to study the postbuckling of circular cylindrical shells subject to axial compression and lateral pressure made of functionally graded graphene platelet-reinforced polymer composite (FG-GPL-RPC). The governing equations are obtained in the context of the classical Donnell shell theory by the von K′arm′an nonlinear relations. Then, based on the Ritz energy method, an analytical solution approach is used to trace the nonlinear postbuckling path of the shell. The effects of several parameters such as the weight fraction of the graphene platelet (GPL), the geometrical properties, and distribution patterns of the GPL on the postbuckling characteristics of the FG-GPL-RPC shell are analyzed.
文摘The aim of this paper is to set up an efficient nonlinear application algorithm predictive model for a multi aircraft landing dynamic system called “Aircraft Landing Dynamic System, Release 2019<em>A</em><sup>+</sup> version “<em>AIRLADYS R</em>2019<em>A</em><sup>+</sup>”. This programming software combines dynamic programming technic for mathematical computing and optimisation run under AMPL and KNITRO Solver. It uses also a descriptive programming technic for software design. The user interfaces designed in Glade are saved as XML, and by using the GtkBuilder GTK+ object these can be loaded by applications dynamically as needed. By using GtkBuilder, Glade XML files can be used in numerous programming languages including C, C++, C#, Java, Perl, Python, AMPL, etc. Glade is Free Software released under the GNU GPL License. By these tools, the solved problem is a mathematical modelization problem as a non-convex optimal control governed by ordinary non-linear differential equations. The dynamic programming technic is applied because it is a sufficiently high order and it does not require computation of the partial derivatives of the aircraft dynamic. This application will be coded with Linux system on 64 bit operating system, but it can also be run on the windows system. High running performances are obtained with results giving feasible trajectories with a robust optimizing of the objective function.
