应用电子计算机 X 线体层摄影(CT)分析了48例肝癌术后复发病例,复发灶出现时间从6月到6年不等,其中6～18个月内复发的占60.4%,2年内占75%。复发以单病灶为主(43.8%),2个病灶次之(20.8%),3～5个占18.8%,5个以上者仅占16.7%。复发以小病...应用电子计算机 X 线体层摄影(CT)分析了48例肝癌术后复发病例,复发灶出现时间从6月到6年不等,其中6～18个月内复发的占60.4%,2年内占75%。复发以单病灶为主(43.8%),2个病灶次之(20.8%),3～5个占18.8%,5个以上者仅占16.7%。复发以小病灶为特点,≤3cm 者占77.4%,而>5cm 仅有2.7%.CT 主要表现为平扫低密度病灶,增强形式有整个病灶增强和边缘部分增强(80%和20%)。病灶边缘清晰者42.2%。复发灶的 CT 表现与原发性肝癌结节型表现间差异无显著性(P>0.05)。本文还对其中18例再次手术的复发病例与 CT、B 超作了对照分析。CT 的敏感性(90.7%)较 B 超为高(74.4%)。CT 的假阴性率(9.3%)较 B 超为低(25.6%)。病灶大小的估计准确性,两者相近。另外还对肝癌术后随访提出了参考指标。展开更多
Currently,18F-FDG coincidence SPECT(Co-SPECT)/CT scan still serves as an important tool for diagnosis,staging,and evaluation of cancer treatment in developing countries.We implemented full physical corrections(FPC) to...Currently,18F-FDG coincidence SPECT(Co-SPECT)/CT scan still serves as an important tool for diagnosis,staging,and evaluation of cancer treatment in developing countries.We implemented full physical corrections(FPC) to Co-SPECT(quantitative Co-SPECT) to improve the image resolution and contrast along with the capability for image quantitation.FPC included attenuation,scatter,resolution recovery,and noise reduction.A standard NEMA phantom filled with 10:1 F-18 activity concentration ratio in spheres and background was utilized to evaluate image performance.Subsequently,15 patients with histologically confirmed thoracic carcinomas were included to undergo a 18 F-FDG Co-SPECT/CT scan followed by a 18 F-FDG PET/CT scan.Functional parameters as SUVmax,SUVmean,SULpeak,and MTV from both quantitative Co-SPECT and PET were analyzed.Image resolution of Co-SPECT for NEMA phantom was improved to reveal the smallest sphere from a diameter of 28 mm to 22 mm(17 mm for PET).The image contrast was enhanced from 1.7 to 6.32(6.69 for PET) with slightly degraded uniformity in background(3.1% vs.6.7%)(5.6% for PET).Patients’ SUVmax,SUVmean,SULpeak,and MTV measured from quantitative Co-SPECT were overall highly correlated with those from PET(r=0.82-0.88).Adjustment of the threshold of SUVmax and SUV to determine SUVmean and MTV did not further change the correlations with PET(r=0.81-0.88).Adding full physical corrections to Co-SPECT images can significantly improve image resolution and contrast to reveal smaller tumor lesions along with the capability to quantify functional parameters like PET/CT.展开更多
基金supported by the internal research grant from China-Japan Friendship Hospital,Beijing,China(Grant No.2016-1QN-9)。
文摘Currently,18F-FDG coincidence SPECT(Co-SPECT)/CT scan still serves as an important tool for diagnosis,staging,and evaluation of cancer treatment in developing countries.We implemented full physical corrections(FPC) to Co-SPECT(quantitative Co-SPECT) to improve the image resolution and contrast along with the capability for image quantitation.FPC included attenuation,scatter,resolution recovery,and noise reduction.A standard NEMA phantom filled with 10:1 F-18 activity concentration ratio in spheres and background was utilized to evaluate image performance.Subsequently,15 patients with histologically confirmed thoracic carcinomas were included to undergo a 18 F-FDG Co-SPECT/CT scan followed by a 18 F-FDG PET/CT scan.Functional parameters as SUVmax,SUVmean,SULpeak,and MTV from both quantitative Co-SPECT and PET were analyzed.Image resolution of Co-SPECT for NEMA phantom was improved to reveal the smallest sphere from a diameter of 28 mm to 22 mm(17 mm for PET).The image contrast was enhanced from 1.7 to 6.32(6.69 for PET) with slightly degraded uniformity in background(3.1% vs.6.7%)(5.6% for PET).Patients’ SUVmax,SUVmean,SULpeak,and MTV measured from quantitative Co-SPECT were overall highly correlated with those from PET(r=0.82-0.88).Adjustment of the threshold of SUVmax and SUV to determine SUVmean and MTV did not further change the correlations with PET(r=0.81-0.88).Adding full physical corrections to Co-SPECT images can significantly improve image resolution and contrast to reveal smaller tumor lesions along with the capability to quantify functional parameters like PET/CT.
