This study was undertaken to quantify the frequency, clinical course, charges, and outcomes of hyperemesis gravidarum. Study design: California birth certificate data linked with maternal and neonatal hospital dischar...This study was undertaken to quantify the frequency, clinical course, charges, and outcomes of hyperemesis gravidarum. Study design: California birth certificate data linked with maternal and neonatal hospital discharge data in 1999 were used (N = 520,739). Hyperemesis was defined by ICD- 9 codes. The frequency, estimated charges, and demographic characteristics associated with hyperemesis patients were assessed. Maternal and neonatal perinatal outcomes were compared by maternal hyperemesis status. Results: Hyperemesis complicated 2,466 of 520,739 births. The average length of stay was 2.6 days and the average charge was ＄ 5,932. Singleton hyperemesis infants were smaller (3,255 vs 3,380 g; P < .0001 and more likely to be small for gestational age (29.21% vs 20.8% ; P < .0001). Conclusion: Hyperemesis occurs in 473 of 100,000 live births and is associated with significant charges. Infants of mothers with hyperemesis have lower birth weights and the mothers are more likely to have infants that are small for gestational age.展开更多
To editor:Wernicke encephalopathy(WE)is an acute neurological disorder caused by a deficiency of vitamin B1(thiamine),with a prevalence of 1.3%in autopsy studies.1 Eighty-four percent of patients with WE will develop ...To editor:Wernicke encephalopathy(WE)is an acute neurological disorder caused by a deficiency of vitamin B1(thiamine),with a prevalence of 1.3%in autopsy studies.1 Eighty-four percent of patients with WE will develop Korsakoff syndrome,which is characterized by amnesia and confusion.2 Although WE is more common in alcoholics,it can also be caused by vomiting,malnourishment,and other situations.展开更多
文摘This study was undertaken to quantify the frequency, clinical course, charges, and outcomes of hyperemesis gravidarum. Study design: California birth certificate data linked with maternal and neonatal hospital discharge data in 1999 were used (N = 520,739). Hyperemesis was defined by ICD- 9 codes. The frequency, estimated charges, and demographic characteristics associated with hyperemesis patients were assessed. Maternal and neonatal perinatal outcomes were compared by maternal hyperemesis status. Results: Hyperemesis complicated 2,466 of 520,739 births. The average length of stay was 2.6 days and the average charge was ＄ 5,932. Singleton hyperemesis infants were smaller (3,255 vs 3,380 g; P < .0001 and more likely to be small for gestational age (29.21% vs 20.8% ; P < .0001). Conclusion: Hyperemesis occurs in 473 of 100,000 live births and is associated with significant charges. Infants of mothers with hyperemesis have lower birth weights and the mothers are more likely to have infants that are small for gestational age.
文摘To editor:Wernicke encephalopathy(WE)is an acute neurological disorder caused by a deficiency of vitamin B1(thiamine),with a prevalence of 1.3%in autopsy studies.1 Eighty-four percent of patients with WE will develop Korsakoff syndrome,which is characterized by amnesia and confusion.2 Although WE is more common in alcoholics,it can also be caused by vomiting,malnourishment,and other situations.
