BACKGROUND: Secondary lymphedema is one of the common complications after malignant tumor surgery. It is a chronic and complex disease. Once lymphedema occurs, there will be discomfort such as limb swelling, pain, num...BACKGROUND: Secondary lymphedema is one of the common complications after malignant tumor surgery. It is a chronic and complex disease. Once lymphedema occurs, there will be discomfort such as limb swelling, pain, numbness and tension, which will eventually lead to changes in the appearance of the affected limb and will seriously affect the quality of life and require lifelong treatment and psychosocial support. This study investigated the current situation of stigma and alexithymia in patients with lymphedema, and discussed the impact of alexithymia on stigma in patients with lymphedema. AIMS: To understand the current situation of stigma and alexithymia in patients with lymphedema, and to analyze the influence of alexithymia on stigma. METHODS: 195 patients with lymphedema in a hospital were selected by convenient sampling. General information questionnaire, Toronto Alexithymia Scale and social impact scale were used to investigate respectively, to study the general situation, stigma and alexithymia of the respondents. RESULTS: The results showed that the total score of stigma in 195 patients with lymphedema was (60.36 ± 11.08), and the total score of alexithymia was (56.53 ± 8.43). Multiple linear regression analysis showed that alexithymia and family relationship were the influencing factors of stigma in patients with lymphedema. CONCLUSIONS: The patients with lymphedema have obvious stigma, and alexithymia and family relationship are the influencing factors.展开更多
Background: The segmental multi-frequency bioelectrical impedance analysis (SMF-BIA) is a useful method for evaluating physical health and nutritional status in various clinical settings. But less is known about its r...Background: The segmental multi-frequency bioelectrical impedance analysis (SMF-BIA) is a useful method for evaluating physical health and nutritional status in various clinical settings. But less is known about its role in the preoperative assessment of breast cancer patients. Herein, we try to monitor the changes in body composition of preoperative patients by SMF-BIA and figure out its association with clinical features. Methods: The changes in body composition were monitored by SMF-BIA in 563 female patients with breast cancer. Monitor body moisture and collect relevant data on the day before surgery as a prospective study. Retrospective analysis will be conducted based on preoperative data and pathological results after lymph node resection, Spearman’s correlation coefficients were calculated to investigate the correlation among parameters. Results: We found that the body water, extracellular water ratio, and bioelectrical impedance of the affected upper limbs of patients with different tumor stages or different numbers of lymph node metastases were significantly different from those of their healthy upper limbs (P P P P P Conclusion: SMF-BIA can help monitor the changes in body composition of breast cancer patients and provide detailed information for making a personalized treatment plan and individual nursing schedule. However, the value of SMF-BIA in preoperative assessment still needs to be validated in large prospective clinical trials.展开更多
Purpose: The effect of manual lymphatic drainage in patients with breast cancer is controversial. The purpose of this study is to evaluate the role of manual lymphatic drainage (MLD) in breast cancer-related lymphedem...Purpose: The effect of manual lymphatic drainage in patients with breast cancer is controversial. The purpose of this study is to evaluate the role of manual lymphatic drainage (MLD) in breast cancer-related lymphedema treatment. Methods: The electronic databases of EMBASE, PubMed, Web of Science, and The Cochrane Library were searched to find English articles on MLD which were published before January 2020. After two evaluators selected the studies and independently evaluated literature quality, meta-analysis was carried out with RevMan 5.3 software. The outcome index of lymphedema treatment changed in edema volume. Results: The study included six RCTs of 364 patients and the meta-analysis showed no significant difference in the effect of MLD for BCRL compared with other treatments (mean difference, 3.76;95% confidence interval, -35.09 to 42.62;Z, 0.19;p = 0.850). Conclusion: MLD can relieve the body tissue, rapidly improve local condition, and enhance complete decongestive therapy (CDT) efficacy. MLD can prevent BCRL and improve the symptoms of stage I lymphedema. It should be widely applied to prevent BCRL from entering an irreversible state.展开更多
The differential evolution algorithm is an evolutionary algorithm for global optimization and the un-capacitated facility location problem (UFL) is one of the classic NP-Hard problems. In this paper, combined with the...The differential evolution algorithm is an evolutionary algorithm for global optimization and the un-capacitated facility location problem (UFL) is one of the classic NP-Hard problems. In this paper, combined with the specific characteristics of the UFL problem, we introduce the activation function to the algorithm for solving UFL problem and name it improved adaptive differential evolution algorithm (IADEA). Next, to improve the efficiency of the algorithm and to alleviate the problem of being stuck in a local optimum, an adaptive operator was added. To test the improvement of our algorithm, we compare the IADEA with the basic differential evolution algorithm by solving typical instances of UFL problem respectively. Moreover, to compare with other heuristic algorithm, we use the hybrid ant colony algorithm to solve the same instances. The computational results show that IADEA improves the performance of the basic DE and it outperforms the hybrid ant colony algorithm.展开更多
The semi-Lagrangian relaxation （SLR）, a new exactmethod for combinatorial optimization problems with equality constraints,is applied to the quadratic assignment problem （QAP）.A dual ascent algorithm with finite co...The semi-Lagrangian relaxation （SLR）, a new exactmethod for combinatorial optimization problems with equality constraints,is applied to the quadratic assignment problem （QAP）.A dual ascent algorithm with finite convergence is developed forsolving the semi-Lagrangian dual problem associated to the QAP.We perform computational experiments on 30 moderately difficultQAP instances by using the mixed integer programming solvers,Cplex, and SLR＋Cplex, respectively. The numerical results notonly further illustrate that the SLR and the developed dual ascentalgorithm can be used to solve the QAP reasonably, but also disclosean interesting fact： comparing with solving the unreducedproblem, the reduced oracle problem cannot be always effectivelysolved by using Cplex in terms of the CPU time.展开更多
目的了解唐山市接受艾滋病自愿咨询检测(voluntary counseling testing,VCT)服务人群的特征和艾滋病病毒(HIV)以及梅毒感染状况,为更有针对性地开展VCT工作提供科学依据。方法使用Excel 2003软件将2015年唐山市疾病预防控制中心VCT门诊...目的了解唐山市接受艾滋病自愿咨询检测(voluntary counseling testing,VCT)服务人群的特征和艾滋病病毒(HIV)以及梅毒感染状况,为更有针对性地开展VCT工作提供科学依据。方法使用Excel 2003软件将2015年唐山市疾病预防控制中心VCT门诊资料数据导出并建立数据库,使用SPSS 21.0软件进行统计分析,对一般人口学资料进行描述性分析,采用卡方检验比较不同年龄组、不同求询者的HIV、梅毒检测结果。结果共有891人接受咨询检测服务,男女性别比为6.36∶1,29~39岁组青壮年占83.95%;求询者类型以男男性性行为者(men who have sex with men,MSM)为多,占33.11%(295人)。接受HIV检测891人,检出阳性52人,阳性率为5.84%。其中50人为男性,HIV抗体阳性率为6.49%;2人为女性,HIV抗体阳性率为1.65%。不同年龄组求询者的HIV抗体检测结果经x2检验,差异有统计学意义(χ2=81.943,P<0.01)。接受梅毒检测891人,检出阳性11人,阳性率为1.23%。总之,男男同性性行为者HIV抗体和梅毒抗体阳性率最高,分别为15.3%和2.0%;HIV抗体阳性率差异有统计学意义(χ2=71.563,P<0.01)。结论 VCT是发现HIV感染者或艾滋病病例的有效途径,是开展高危行为干预的重要窗口,要加强HIV/梅毒等性传播疾病的检测咨询工作,有效阻断性传播疾病在同性和异性间的传播。展开更多
文摘BACKGROUND: Secondary lymphedema is one of the common complications after malignant tumor surgery. It is a chronic and complex disease. Once lymphedema occurs, there will be discomfort such as limb swelling, pain, numbness and tension, which will eventually lead to changes in the appearance of the affected limb and will seriously affect the quality of life and require lifelong treatment and psychosocial support. This study investigated the current situation of stigma and alexithymia in patients with lymphedema, and discussed the impact of alexithymia on stigma in patients with lymphedema. AIMS: To understand the current situation of stigma and alexithymia in patients with lymphedema, and to analyze the influence of alexithymia on stigma. METHODS: 195 patients with lymphedema in a hospital were selected by convenient sampling. General information questionnaire, Toronto Alexithymia Scale and social impact scale were used to investigate respectively, to study the general situation, stigma and alexithymia of the respondents. RESULTS: The results showed that the total score of stigma in 195 patients with lymphedema was (60.36 ± 11.08), and the total score of alexithymia was (56.53 ± 8.43). Multiple linear regression analysis showed that alexithymia and family relationship were the influencing factors of stigma in patients with lymphedema. CONCLUSIONS: The patients with lymphedema have obvious stigma, and alexithymia and family relationship are the influencing factors.
文摘Background: The segmental multi-frequency bioelectrical impedance analysis (SMF-BIA) is a useful method for evaluating physical health and nutritional status in various clinical settings. But less is known about its role in the preoperative assessment of breast cancer patients. Herein, we try to monitor the changes in body composition of preoperative patients by SMF-BIA and figure out its association with clinical features. Methods: The changes in body composition were monitored by SMF-BIA in 563 female patients with breast cancer. Monitor body moisture and collect relevant data on the day before surgery as a prospective study. Retrospective analysis will be conducted based on preoperative data and pathological results after lymph node resection, Spearman’s correlation coefficients were calculated to investigate the correlation among parameters. Results: We found that the body water, extracellular water ratio, and bioelectrical impedance of the affected upper limbs of patients with different tumor stages or different numbers of lymph node metastases were significantly different from those of their healthy upper limbs (P P P P P Conclusion: SMF-BIA can help monitor the changes in body composition of breast cancer patients and provide detailed information for making a personalized treatment plan and individual nursing schedule. However, the value of SMF-BIA in preoperative assessment still needs to be validated in large prospective clinical trials.
文摘Purpose: The effect of manual lymphatic drainage in patients with breast cancer is controversial. The purpose of this study is to evaluate the role of manual lymphatic drainage (MLD) in breast cancer-related lymphedema treatment. Methods: The electronic databases of EMBASE, PubMed, Web of Science, and The Cochrane Library were searched to find English articles on MLD which were published before January 2020. After two evaluators selected the studies and independently evaluated literature quality, meta-analysis was carried out with RevMan 5.3 software. The outcome index of lymphedema treatment changed in edema volume. Results: The study included six RCTs of 364 patients and the meta-analysis showed no significant difference in the effect of MLD for BCRL compared with other treatments (mean difference, 3.76;95% confidence interval, -35.09 to 42.62;Z, 0.19;p = 0.850). Conclusion: MLD can relieve the body tissue, rapidly improve local condition, and enhance complete decongestive therapy (CDT) efficacy. MLD can prevent BCRL and improve the symptoms of stage I lymphedema. It should be widely applied to prevent BCRL from entering an irreversible state.
文摘The differential evolution algorithm is an evolutionary algorithm for global optimization and the un-capacitated facility location problem (UFL) is one of the classic NP-Hard problems. In this paper, combined with the specific characteristics of the UFL problem, we introduce the activation function to the algorithm for solving UFL problem and name it improved adaptive differential evolution algorithm (IADEA). Next, to improve the efficiency of the algorithm and to alleviate the problem of being stuck in a local optimum, an adaptive operator was added. To test the improvement of our algorithm, we compare the IADEA with the basic differential evolution algorithm by solving typical instances of UFL problem respectively. Moreover, to compare with other heuristic algorithm, we use the hybrid ant colony algorithm to solve the same instances. The computational results show that IADEA improves the performance of the basic DE and it outperforms the hybrid ant colony algorithm.
基金supported by the National Natural Science Foundation of China(71401106)the Innovation Program of Shanghai Municipal Education Commission(14YZ090)+4 种基金the Shanghai Natural Science Foundation(14ZR1418700)the Shanghai First-class Academic Discipline Project(S1201YLXK)the Hujiang Foundation of China(A14006)the grant S2009/esp-1594 from the Comunidad de Madrid(Spain)the grant MTM2012-36163-C06-06 from the Spanish government
文摘The semi-Lagrangian relaxation （SLR）, a new exactmethod for combinatorial optimization problems with equality constraints,is applied to the quadratic assignment problem （QAP）.A dual ascent algorithm with finite convergence is developed forsolving the semi-Lagrangian dual problem associated to the QAP.We perform computational experiments on 30 moderately difficultQAP instances by using the mixed integer programming solvers,Cplex, and SLR＋Cplex, respectively. The numerical results notonly further illustrate that the SLR and the developed dual ascentalgorithm can be used to solve the QAP reasonably, but also disclosean interesting fact： comparing with solving the unreducedproblem, the reduced oracle problem cannot be always effectivelysolved by using Cplex in terms of the CPU time.
文摘目的了解唐山市接受艾滋病自愿咨询检测(voluntary counseling testing,VCT)服务人群的特征和艾滋病病毒(HIV)以及梅毒感染状况,为更有针对性地开展VCT工作提供科学依据。方法使用Excel 2003软件将2015年唐山市疾病预防控制中心VCT门诊资料数据导出并建立数据库,使用SPSS 21.0软件进行统计分析,对一般人口学资料进行描述性分析,采用卡方检验比较不同年龄组、不同求询者的HIV、梅毒检测结果。结果共有891人接受咨询检测服务,男女性别比为6.36∶1,29~39岁组青壮年占83.95%;求询者类型以男男性性行为者(men who have sex with men,MSM)为多,占33.11%(295人)。接受HIV检测891人,检出阳性52人,阳性率为5.84%。其中50人为男性,HIV抗体阳性率为6.49%;2人为女性,HIV抗体阳性率为1.65%。不同年龄组求询者的HIV抗体检测结果经x2检验,差异有统计学意义(χ2=81.943,P<0.01)。接受梅毒检测891人,检出阳性11人,阳性率为1.23%。总之,男男同性性行为者HIV抗体和梅毒抗体阳性率最高,分别为15.3%和2.0%;HIV抗体阳性率差异有统计学意义(χ2=71.563,P<0.01)。结论 VCT是发现HIV感染者或艾滋病病例的有效途径,是开展高危行为干预的重要窗口,要加强HIV/梅毒等性传播疾病的检测咨询工作,有效阻断性传播疾病在同性和异性间的传播。
