Atmospheric humic-like substances (HULIS) are not only an unresolved mixture of macro- organic compounds but also powerful chelating agents in atmospheric particulate matters (PMs); impacting on both the propertie...Atmospheric humic-like substances (HULIS) are not only an unresolved mixture of macro- organic compounds but also powerful chelating agents in atmospheric particulate matters (PMs); impacting on both the properties of aerosol particles and health effects by generating reactive oxygen spedes (ROS). Currently, the interests of HULIS are intensively shifting to the investigations of HULIS-metal synergic effects and kinetics modeling studies, as well as the development of HULIS quantification, findings of possible HULIS sources and generation of ROS from HULIS. In light of HULIS studies, we comprehensively review the current knowledge of isolation and physicochemical characterization of HULIS from atmospheric samples as well as HULIS properties (hygroscopic, surface activity, and colloidal) and possible sources of HULIS. This review mainly highlights the generation of reactive oxygen species (ROS) from PMs, HULIS and transition metals, especially iron. This review also summarized the mechanism of iron-organic complexation and recent findings of OH formation from HULIS-metal complexes. This review will be helpful to carry out the modeling studies that concern with HULIS-transition metals and for further studies in the generation of ROS from HULIS-metal complexes,展开更多
The long-term earthquake prediction from 2021 to 2030 is carried out by researching the active tectonic block boundary zones in the Chinese mainland.Based on the strong earthquake recurrence model,the cumulative proba...The long-term earthquake prediction from 2021 to 2030 is carried out by researching the active tectonic block boundary zones in the Chinese mainland.Based on the strong earthquake recurrence model,the cumulative probability of each target fault in the next 10 years is given by the recurrence period and elapsed time of each fault,which are adopted from relevant studies such as seismological geology,geodesy,and historical earthquake records.Based on the long-term predictions of large earthquakes throughout the world,this paper proposes a comprehensive judgment scheme based on the fault segments with the seismic gap,motion strongly locked,sparse small-moderate earthquakes,and apparent Coulomb stress increase.This paper presents a comprehensive analysis of the relative risk for strong earthquakes that may occur in the coming 10 years on the major faults in the active tectonic block boundary zones in the Chinese mainland.The present loading rate of each fault is first constrained by geodetic observations;the cumulative displacement of each fault is then estimated by the elapsed time since the most recent strong earthquake.展开更多
Background:The Middle cerebral artery (MCA) aneurysm is a common type of craniocerebral aneurysm that is prone to rupture and high mortality. The classic surgical approaches are the Pterional approach and the Lateral ...Background:The Middle cerebral artery (MCA) aneurysm is a common type of craniocerebral aneurysm that is prone to rupture and high mortality. The classic surgical approaches are the Pterional approach and the Lateral Supraorbital (LSO) approach, but there are shortcomings. Methods:This study retrospectively analyzed clinical and imaging data from 181 patients with MCA aneurysm clipping in the Department of Neurosurgery, First Affiliated Hospital of Soochow University between 2011 and 2017. Statistical analysis using parametric and nonparametric tests showed that P values below 0.05 were considered statistically significant. Results: The preoperative GCS score (P=0.003), Hunt-Hess scale (P < 0.001) and the operating habits of the surgeon (P < 0.001) affected the surgeon to choose a surgical approach. The choice of two surgical methods on the operation time (P < 0.001), skin incision (P < 0.001), complications (P=0.026), tracheotomy (P=0.014), prognosis (P=0.002) were significantly different. Different surgical approaches (P=0.002), Hunt-Hess scale (P <0.001), GCS scale (P < 0.001), GCS sorse (P < 0.001), skin incision (P=0.031) and complications (P < 0.001) are closely related to the prognosis of patients. Conclusions: Modified LSO approach provides another surgical approach for MCA aneurysm clipping, while avoiding the drawbacks of the LSO approach in the clipping of MCA distal aneurysm.展开更多
In situ bioprinting is promising for developing scaffolds directly on defect models in operating rooms,which provides a new strategy for in situ tissue regeneration.However,due to the limitation of existing in situ bi...In situ bioprinting is promising for developing scaffolds directly on defect models in operating rooms,which provides a new strategy for in situ tissue regeneration.However,due to the limitation of existing in situ biofabrication technologies including printing depth and suitable bioinks,bioprinting scaffolds in deep dermal or extremity injuries remains a grand challenge.Here,we present an in vivo scaffold fabrication approach by minimally invasive bioprinting electroactive hydrogel scaffolds to promote in situ tissue regeneration.The minimally invasive bioprinting system consists of a ferromagnetic soft catheter robot for extrusion,a digital laparoscope for in situ monitoring,and a Veress needle for establishing a pneumoperitoneum.After 3D reconstruction of the defects with computed tomography,electroactive hydrogel scaffolds are printed within partial liver resection of live rats,and in situ tissue regeneration is achieved by promoting the proliferation,migration,and differentiation of cells and maintaining liver function in vivo.展开更多
JUNO is a multi-purpose neutrino observatory under construction in the south of China.This publication presents new sensitivity estimates for the measurement of the △m_(31)^(2),△m_(21)^(2),sin^(2)θ_(12),and sin^(2)...JUNO is a multi-purpose neutrino observatory under construction in the south of China.This publication presents new sensitivity estimates for the measurement of the △m_(31)^(2),△m_(21)^(2),sin^(2)θ_(12),and sin^(2)θ_(13) oscillation parameters using reactor antineutrinos,which is one of the primary physics goals of the experiment.The sensitivities are obtained using the best knowledge available to date on the location and overburden of the experimental site,the nuclear reactors in the surrounding area and beyond,the detector response uncertainties,and the reactor antineutrino spectral shape constraints expected from the TAO satellite detector.It is found that the △m_(21)^(2) and sin^(2)θ_(12) oscillation parameters will be determined to 0.5%precision or better in six years of data collection.In the same period,the △m_(31)^(2) parameter will be determined to about 0.2%precision for each mass ordering hypothesis.The new precision represents approximately an order of magnitude improvement over existing constraints for these three parameters.展开更多
为了厘清安徽的皖南山区和大别山区常见药用植物资源的分布情况,通过对皖南山区和大别山区的多次野外实地调查、标本采集和鉴定,发现了分布于安徽皖南山区和大别山区的6个新记录种,分别是天南星科湘南星Arisaema hunanense Hand.-Mazt....为了厘清安徽的皖南山区和大别山区常见药用植物资源的分布情况,通过对皖南山区和大别山区的多次野外实地调查、标本采集和鉴定,发现了分布于安徽皖南山区和大别山区的6个新记录种,分别是天南星科湘南星Arisaema hunanense Hand.-Mazt.,姜科绿苞蘘荷Zingiber viridescens Z.H.Chen, G.Y.Li et W.J.Chen,,木兰科罗田玉兰Yulania pilocarpa(Z. Z. Zhao&Z. W. Xie) D. L. Fu,五味子科日本南五味子Kadsura japonica(L.) Dunal,旋花科毛牵牛Ipomoea biflora(Linnaeus) Persoon和茜草科卵叶茜草Rubia ovatifolia Z. Y. Zhang,凭证标本存放于安徽中医药大学腊叶标本馆(ACM)。这些新记录种的发现丰富了安徽省药用植物资源,为该地区的植物研究提供了参考,也表明安徽的山区植物资源的调查工作有待细致深入地开展。展开更多
We measured the contact angles of Al and Sn drops on polycrystalline Al2O3 substrates in various high magnetic fields at different temperatures.The contact angles of both Al and Sn drops on the Al2O3 substrates decrea...We measured the contact angles of Al and Sn drops on polycrystalline Al2O3 substrates in various high magnetic fields at different temperatures.The contact angles of both Al and Sn drops on the Al2O3 substrates decreased under high magnetic fields.These decreases strongly depend on the temperature,magnetic flux density,magnetic properties of the metal drops,and the reactivity of the metal drops with Al2O3.Our results reveal that the wetting behavior of molten metal drops on ceramics can be modified by a high magnetic field.展开更多
基金the Natural Science Foundation of China under NSFC Grant No. 21477073, 41273127 for support to conduct this research
文摘Atmospheric humic-like substances (HULIS) are not only an unresolved mixture of macro- organic compounds but also powerful chelating agents in atmospheric particulate matters (PMs); impacting on both the properties of aerosol particles and health effects by generating reactive oxygen spedes (ROS). Currently, the interests of HULIS are intensively shifting to the investigations of HULIS-metal synergic effects and kinetics modeling studies, as well as the development of HULIS quantification, findings of possible HULIS sources and generation of ROS from HULIS. In light of HULIS studies, we comprehensively review the current knowledge of isolation and physicochemical characterization of HULIS from atmospheric samples as well as HULIS properties (hygroscopic, surface activity, and colloidal) and possible sources of HULIS. This review mainly highlights the generation of reactive oxygen species (ROS) from PMs, HULIS and transition metals, especially iron. This review also summarized the mechanism of iron-organic complexation and recent findings of OH formation from HULIS-metal complexes. This review will be helpful to carry out the modeling studies that concern with HULIS-transition metals and for further studies in the generation of ROS from HULIS-metal complexes,
基金the National Key R&D Program of China(grants 2017YFC1500501).
文摘The long-term earthquake prediction from 2021 to 2030 is carried out by researching the active tectonic block boundary zones in the Chinese mainland.Based on the strong earthquake recurrence model,the cumulative probability of each target fault in the next 10 years is given by the recurrence period and elapsed time of each fault,which are adopted from relevant studies such as seismological geology,geodesy,and historical earthquake records.Based on the long-term predictions of large earthquakes throughout the world,this paper proposes a comprehensive judgment scheme based on the fault segments with the seismic gap,motion strongly locked,sparse small-moderate earthquakes,and apparent Coulomb stress increase.This paper presents a comprehensive analysis of the relative risk for strong earthquakes that may occur in the coming 10 years on the major faults in the active tectonic block boundary zones in the Chinese mainland.The present loading rate of each fault is first constrained by geodetic observations;the cumulative displacement of each fault is then estimated by the elapsed time since the most recent strong earthquake.
文摘Background:The Middle cerebral artery (MCA) aneurysm is a common type of craniocerebral aneurysm that is prone to rupture and high mortality. The classic surgical approaches are the Pterional approach and the Lateral Supraorbital (LSO) approach, but there are shortcomings. Methods:This study retrospectively analyzed clinical and imaging data from 181 patients with MCA aneurysm clipping in the Department of Neurosurgery, First Affiliated Hospital of Soochow University between 2011 and 2017. Statistical analysis using parametric and nonparametric tests showed that P values below 0.05 were considered statistically significant. Results: The preoperative GCS score (P=0.003), Hunt-Hess scale (P < 0.001) and the operating habits of the surgeon (P < 0.001) affected the surgeon to choose a surgical approach. The choice of two surgical methods on the operation time (P < 0.001), skin incision (P < 0.001), complications (P=0.026), tracheotomy (P=0.014), prognosis (P=0.002) were significantly different. Different surgical approaches (P=0.002), Hunt-Hess scale (P <0.001), GCS scale (P < 0.001), GCS sorse (P < 0.001), skin incision (P=0.031) and complications (P < 0.001) are closely related to the prognosis of patients. Conclusions: Modified LSO approach provides another surgical approach for MCA aneurysm clipping, while avoiding the drawbacks of the LSO approach in the clipping of MCA distal aneurysm.
基金supported by the National Natural Science Foundation of China(52173280,51820105008,82173315,82072068,81773104,81873931,and 81974382)the Technical Innovation Major Foundation Program of Hubei Province(2018ACA136)+1 种基金the Integrated Innovative Team for Major Human Diseases Program of Tongji Medical College,HUSTthe Academic Doctor-Supporting Program of Tongji Medical College,HUST.
文摘In situ bioprinting is promising for developing scaffolds directly on defect models in operating rooms,which provides a new strategy for in situ tissue regeneration.However,due to the limitation of existing in situ biofabrication technologies including printing depth and suitable bioinks,bioprinting scaffolds in deep dermal or extremity injuries remains a grand challenge.Here,we present an in vivo scaffold fabrication approach by minimally invasive bioprinting electroactive hydrogel scaffolds to promote in situ tissue regeneration.The minimally invasive bioprinting system consists of a ferromagnetic soft catheter robot for extrusion,a digital laparoscope for in situ monitoring,and a Veress needle for establishing a pneumoperitoneum.After 3D reconstruction of the defects with computed tomography,electroactive hydrogel scaffolds are printed within partial liver resection of live rats,and in situ tissue regeneration is achieved by promoting the proliferation,migration,and differentiation of cells and maintaining liver function in vivo.
基金Supported by the Chinese Academy of Sciencesthe National Key R&D Program of China+18 种基金the CAS Center for Excellence in Particle Physics,Wuyi Universitythe Tsung-Dao Lee Institute of Shanghai Jiao Tong University in Chinathe Institut National de Physique Nucléaire et de Physique de Particules(IN2P3)in Francethe Istituto Nazionale di Fisica Nucleare(INFN)in Italythe Italian-Chinese collaborative research program MAECI-NSFCthe Fond de la Recherche Scientifique(F.R.S-FNRS)FWO under the“Excellence of Science-EOS in Belgium”the Conselho Nacional de Desenvolvimento Científico e Tecnològico in Brazilthe Agencia Nacional de Investigacion y Desarrollo and ANID-Millennium Science Initiative Program-ICN2019_044 in Chilethe Charles University Research Centre and the Ministry of Education,Youth,and Sports in Czech Republicthe Deutsche Forschungsgemeinschaft(DFG)the Helmholtz Associationthe Cluster of Excellence PRISMA+in Germanythe Joint Institute of Nuclear Research(JINR)and Lomonosov Moscow State University in Russiathe joint Russian Science Foundation(RSF)National Natural Science Foundation of China(NSFC)research programthe MOST and MOE in Taiwanthe Chulalongkorn University and Suranaree University of Technology in Thailand,University of California at Irvinethe National Science Foundation in USA。
文摘JUNO is a multi-purpose neutrino observatory under construction in the south of China.This publication presents new sensitivity estimates for the measurement of the △m_(31)^(2),△m_(21)^(2),sin^(2)θ_(12),and sin^(2)θ_(13) oscillation parameters using reactor antineutrinos,which is one of the primary physics goals of the experiment.The sensitivities are obtained using the best knowledge available to date on the location and overburden of the experimental site,the nuclear reactors in the surrounding area and beyond,the detector response uncertainties,and the reactor antineutrino spectral shape constraints expected from the TAO satellite detector.It is found that the △m_(21)^(2) and sin^(2)θ_(12) oscillation parameters will be determined to 0.5%precision or better in six years of data collection.In the same period,the △m_(31)^(2) parameter will be determined to about 0.2%precision for each mass ordering hypothesis.The new precision represents approximately an order of magnitude improvement over existing constraints for these three parameters.
文摘为了厘清安徽的皖南山区和大别山区常见药用植物资源的分布情况,通过对皖南山区和大别山区的多次野外实地调查、标本采集和鉴定,发现了分布于安徽皖南山区和大别山区的6个新记录种,分别是天南星科湘南星Arisaema hunanense Hand.-Mazt.,姜科绿苞蘘荷Zingiber viridescens Z.H.Chen, G.Y.Li et W.J.Chen,,木兰科罗田玉兰Yulania pilocarpa(Z. Z. Zhao&Z. W. Xie) D. L. Fu,五味子科日本南五味子Kadsura japonica(L.) Dunal,旋花科毛牵牛Ipomoea biflora(Linnaeus) Persoon和茜草科卵叶茜草Rubia ovatifolia Z. Y. Zhang,凭证标本存放于安徽中医药大学腊叶标本馆(ACM)。这些新记录种的发现丰富了安徽省药用植物资源,为该地区的植物研究提供了参考,也表明安徽的山区植物资源的调查工作有待细致深入地开展。
基金financially supported by the National Natural Science Foundation of China(Grant Nos.51774086,51574073,51425401,and 51690161)Fundamental Research Funds for the Central Universities(Grant Nos.N180915002,N170902002 and N170908001)Liaoning Innovative Research Team in University,China(Grant No.LT2017011).
文摘We measured the contact angles of Al and Sn drops on polycrystalline Al2O3 substrates in various high magnetic fields at different temperatures.The contact angles of both Al and Sn drops on the Al2O3 substrates decreased under high magnetic fields.These decreases strongly depend on the temperature,magnetic flux density,magnetic properties of the metal drops,and the reactivity of the metal drops with Al2O3.Our results reveal that the wetting behavior of molten metal drops on ceramics can be modified by a high magnetic field.