BACKGROUND Perception is frequently impaired in patients with Alzheimer’s disease(AD).Several patients exhibit visual or haptic hallucinations.CASE SUMMARY A 71-year-old Chinese man presented with visual and haptic h...BACKGROUND Perception is frequently impaired in patients with Alzheimer’s disease(AD).Several patients exhibit visual or haptic hallucinations.CASE SUMMARY A 71-year-old Chinese man presented with visual and haptic hallucinations he had been experiencing for 2 weeks.The clinical manifestations were the feeling of insects crawling and biting the limbs and geison.He looked for the insects while itching and scratching,which led to skin breakage on the limbs.He was treated with topical and anti-allergic drugs in several dermatology departments without any significant improvement.After admission,the patient was administered risperidone(0.5 mg)and duloxetine(2 mg/day).One week later,the dose of risperidone was increased to 2 mg/day,and that of duloxetine was increased to 60 mg/day.After 2 weeks of treatment,the patient’s sensation of insects crawling and biting disappeared,and his mood stabilized.CONCLUSION This patient manifested psychiatric behavioral symptoms caused by AD brain atrophy.It was important to re-evaluate the patient’s cognitive-psychological status when the patient repeatedly went to the hospital for treatment.Follow-up attention to cognitive function and the consideration of perceptual deficits as early manifestations of AD should be considered.展开更多
目的评估维持性血液透析(maintenance hemodialysis,MHD)动静脉内瘘右利手患者的双侧上肢功能,了解动静脉内瘘对上肢功能的影响及内瘘侧上肢功能的影响因素。方法横断面研究,纳入北京市6家血液透析中心的MHD动静脉内瘘且右利手患者,收...目的评估维持性血液透析(maintenance hemodialysis,MHD)动静脉内瘘右利手患者的双侧上肢功能,了解动静脉内瘘对上肢功能的影响及内瘘侧上肢功能的影响因素。方法横断面研究,纳入北京市6家血液透析中心的MHD动静脉内瘘且右利手患者,收集人口学资料、生化资料、握力、关节活动度及简易上肢功能检查(simple test for evaluating hand function,STEF)等上肢功能指标。内瘘侧及非内瘘侧上肢功能的比较采用t检验(或非参数检验),采用多元线性回归分析MHD患者动静脉内瘘侧握力的影响因素。结果共入组MHD患者90例,其中男性51例(56.7%),年龄(59.63±10.60)岁,中位透析龄62.50(24.00,113.00)月。患者非内瘘侧握力高于内瘘侧握力(t=-5.133,P<0.001);多元线性回归结果显示MHD患者内瘘侧握力与血肌酐(β=0.353,P<0.001)、认知功能评分(β=0.223,P=0.006)呈正相关,与尿素清除指数(Kt/V)呈负相关(β=-0.235,P=0.007),男性握力大于女性(β=-0.253,P=0.004)。非内瘘侧腕关节尺偏的角度大于内瘘侧(t=-2.814,P=0.006)。在STEF各项操作中,内瘘侧在大球(t=2.327,P=0.021)、大圆片(t=2.472,P=0.015)、布(t=2.688,P=0.008)项目中操作时间长于无内瘘侧。结论MHD患者内瘘侧握力、关节活动度及灵活性均存在下降,影响内瘘侧握力的因素包括性别、血肌酐、Kt/V和认知功能评分。展开更多
Airbrush spray deposition is applied to fabricate a bilayer heterojunction solar cell based on P3HT/PCBM.This solar cell device shows an open-circuit voltage of 0.36V,a short circuit current density of 6.76mA/cm2,a co...Airbrush spray deposition is applied to fabricate a bilayer heterojunction solar cell based on P3HT/PCBM.This solar cell device shows an open-circuit voltage of 0.36V,a short circuit current density of 6.76mA/cm2,a conversion efficiency of 0.74%,and a fill factor of 30.4%.The results demonstrate that airbrush spray deposition is an effective method to fabricate multilayer or other complex polymer-based organic solar cells.Although spin-coated bulk heterojunction devices have better performance than the airbrushed ones,the airbrush is indeed feasible as a low-cost yet simple process.It is noteworthy that such preliminary results of the airbrush spray solar cell is unoptimized and thus its performance can be further improved with the development of this technology.Furthermore,this method itself has huge potential as it can be used for other polymer-based organic thin film devices.展开更多
The energy-saving reconstruction market of existing buildings is a complex system.It includes three subsystems:service market,capital market and technology market.The service market takes the relationship between ener...The energy-saving reconstruction market of existing buildings is a complex system.It includes three subsystems:service market,capital market and technology market.The service market takes the relationship between energy service companies and owners as the core to establish service associated relationships.The capital market is based on the mechanism of"investment guarantees and risk sharing"to form structures of the capital market.The technology market relies on the"industry-university-research"mode to build technology supporting platforms.Being interdependent and mutually restricted,the three subsystems form the complete system of existing buildings in energy-saving reconstruction.展开更多
The lattice Boltzmann method is widely used in solving hydrodynamics for various systems.The accuracy of the extrapolation method for boundary conditions and Mei’s method for curved boundary is not high enough.We pro...The lattice Boltzmann method is widely used in solving hydrodynamics for various systems.The accuracy of the extrapolation method for boundary conditions and Mei’s method for curved boundary is not high enough.We propose a modified extrapolation method for boundary conditions.Numerical simulations conform the higher accuracy and stability compared with the other methods.展开更多
文摘BACKGROUND Perception is frequently impaired in patients with Alzheimer’s disease(AD).Several patients exhibit visual or haptic hallucinations.CASE SUMMARY A 71-year-old Chinese man presented with visual and haptic hallucinations he had been experiencing for 2 weeks.The clinical manifestations were the feeling of insects crawling and biting the limbs and geison.He looked for the insects while itching and scratching,which led to skin breakage on the limbs.He was treated with topical and anti-allergic drugs in several dermatology departments without any significant improvement.After admission,the patient was administered risperidone(0.5 mg)and duloxetine(2 mg/day).One week later,the dose of risperidone was increased to 2 mg/day,and that of duloxetine was increased to 60 mg/day.After 2 weeks of treatment,the patient’s sensation of insects crawling and biting disappeared,and his mood stabilized.CONCLUSION This patient manifested psychiatric behavioral symptoms caused by AD brain atrophy.It was important to re-evaluate the patient’s cognitive-psychological status when the patient repeatedly went to the hospital for treatment.Follow-up attention to cognitive function and the consideration of perceptual deficits as early manifestations of AD should be considered.
文摘目的评估维持性血液透析(maintenance hemodialysis,MHD)动静脉内瘘右利手患者的双侧上肢功能,了解动静脉内瘘对上肢功能的影响及内瘘侧上肢功能的影响因素。方法横断面研究,纳入北京市6家血液透析中心的MHD动静脉内瘘且右利手患者,收集人口学资料、生化资料、握力、关节活动度及简易上肢功能检查(simple test for evaluating hand function,STEF)等上肢功能指标。内瘘侧及非内瘘侧上肢功能的比较采用t检验(或非参数检验),采用多元线性回归分析MHD患者动静脉内瘘侧握力的影响因素。结果共入组MHD患者90例,其中男性51例(56.7%),年龄(59.63±10.60)岁,中位透析龄62.50(24.00,113.00)月。患者非内瘘侧握力高于内瘘侧握力(t=-5.133,P<0.001);多元线性回归结果显示MHD患者内瘘侧握力与血肌酐(β=0.353,P<0.001)、认知功能评分(β=0.223,P=0.006)呈正相关,与尿素清除指数(Kt/V)呈负相关(β=-0.235,P=0.007),男性握力大于女性(β=-0.253,P=0.004)。非内瘘侧腕关节尺偏的角度大于内瘘侧(t=-2.814,P=0.006)。在STEF各项操作中,内瘘侧在大球(t=2.327,P=0.021)、大圆片(t=2.472,P=0.015)、布(t=2.688,P=0.008)项目中操作时间长于无内瘘侧。结论MHD患者内瘘侧握力、关节活动度及灵活性均存在下降,影响内瘘侧握力的因素包括性别、血肌酐、Kt/V和认知功能评分。
基金Supported by Beijing Municipal Science&Technology Commission(No Z090803044009001)the National Natural Science Foundation of China under Grant Nos 60977027 and 60825407.
文摘Airbrush spray deposition is applied to fabricate a bilayer heterojunction solar cell based on P3HT/PCBM.This solar cell device shows an open-circuit voltage of 0.36V,a short circuit current density of 6.76mA/cm2,a conversion efficiency of 0.74%,and a fill factor of 30.4%.The results demonstrate that airbrush spray deposition is an effective method to fabricate multilayer or other complex polymer-based organic solar cells.Although spin-coated bulk heterojunction devices have better performance than the airbrushed ones,the airbrush is indeed feasible as a low-cost yet simple process.It is noteworthy that such preliminary results of the airbrush spray solar cell is unoptimized and thus its performance can be further improved with the development of this technology.Furthermore,this method itself has huge potential as it can be used for other polymer-based organic thin film devices.
基金supported by National Natural Science Fundation of China(Grant No.71573188)Later-stage Humanities and Social Sciences Subsidized Project of Ministry of Education(Grant No.16JHQ031)Tianjin Social Sciences Planning Post-funded Projects(Grant No.TJGLHQ1403).
文摘The energy-saving reconstruction market of existing buildings is a complex system.It includes three subsystems:service market,capital market and technology market.The service market takes the relationship between energy service companies and owners as the core to establish service associated relationships.The capital market is based on the mechanism of"investment guarantees and risk sharing"to form structures of the capital market.The technology market relies on the"industry-university-research"mode to build technology supporting platforms.Being interdependent and mutually restricted,the three subsystems form the complete system of existing buildings in energy-saving reconstruction.
基金Supported by Shanghai Science and Technology Commission Projects of Leading Scientists and Excellent Academic Leaders under Grand No 11XD1402300Research on Lattice Boltzmann Method for Complex and Moving Boundary Problems under Grant No K.13-0401-13-001 from Shanghai University.
文摘The lattice Boltzmann method is widely used in solving hydrodynamics for various systems.The accuracy of the extrapolation method for boundary conditions and Mei’s method for curved boundary is not high enough.We propose a modified extrapolation method for boundary conditions.Numerical simulations conform the higher accuracy and stability compared with the other methods.
