Mode splitters that directly separate modes without changing their orders are highly promising to improve the flexibility of the mode-division multiplexing systems.In this paper,we design a high-performance mode split...Mode splitters that directly separate modes without changing their orders are highly promising to improve the flexibility of the mode-division multiplexing systems.In this paper,we design a high-performance mode splitter on the silicon-oninsulator platform with a compact footprint of 14μm×2.5μm using an inverse design method based on shape optimization.The fabrication of this mode splitter requires only a single lithography step and exhibits good fabrication tolerances.The experimental results show that the proposed device exhibits state-of-the-art insertion loss(<0.9 dB)and cross talk(<-16 dB)over a broad bandwidth(1500-1600 nm).Furthermore,the shape optimization method used is implemented to design a dual-mode(de)multiplexer,and the experimental results fulfill the design objective,demonstrating the excellent generality of the design method in this paper.展开更多
Identifying influential nodes in complex networks and ranking their importance plays an important role in many fields such as public opinion analysis, marketing, epidemic prevention and control. To solve the issue of ...Identifying influential nodes in complex networks and ranking their importance plays an important role in many fields such as public opinion analysis, marketing, epidemic prevention and control. To solve the issue of the existing node centrality measure only considering the specific statistical feature of a single dimension, a SLGC model is proposed that combines a node’s self-influence, its local neighborhood influence, and global influence to identify influential nodes in the network. The exponential function of e is introduced to measure the node’s self-influence;in the local neighborhood,the node’s one-hop neighboring nodes and two-hop neighboring nodes are considered, while the information entropy is introduced to measure the node’s local influence;the topological position of the node in the network and the shortest path between nodes are considered to measure the node’s global influence. To demonstrate the effectiveness of the proposed model, extensive comparison experiments are conducted with eight existing node centrality measures on six real network data sets using node differentiation ability experiments, susceptible–infected–recovered(SIR) model and network efficiency as evaluation criteria. The experimental results show that the method can identify influential nodes in complex networks more accurately.展开更多
Objective:The aim of paper is to find ecological suitable regionalization of Melicope ptelefolia planting and provide a reference for the rational planning of Good Agricultural Practices(GAP).Methods:The natural ecolo...Objective:The aim of paper is to find ecological suitable regionalization of Melicope ptelefolia planting and provide a reference for the rational planning of Good Agricultural Practices(GAP).Methods:The natural ecological niches of Melicope ptelefolia was taken as basic point.The adaptable areas of Melicope ptelefolia was analysed throughout the whole nation by using Geographic Information System for Traditional Chinese Medicine(TCMGIS).Results:Besides the original distribbution region of Guangxi,Guangdong,Hainan,Yunnan,Fujian,Jiangxi,Hunan,Guizhou,we further found that Zhejiang,Taiwan,Hong Kong,Chongqing,Sichuan are adaptable for the growth of Melicope ptelefolia.The most suitable region is Guangxi,and the followed is Guangdong.Conclusion:The ecological suitable area of Melicope ptelefolia mainly distributes in Lingnan Region,and TCMGIS is comparatively scientific and accurate to analyze suitable areas for the growth of Melicope ptelefolia.These findings have important reference value for the introduction,cultivation and scientific planning of Melicope ptelefolia.展开更多
Objective To investigate the effects of sotetsuflavone on endostatin, transforming growth factor-β （TGF-β）, signal transducers and activators of transcription 3 （STAT3）, β-catenin and zonula occludens-1 prote...Objective To investigate the effects of sotetsuflavone on endostatin, transforming growth factor-β （TGF-β）, signal transducers and activators of transcription 3 （STAT3）, β-catenin and zonula occludens-1 protein （ZO-1） in non-small cell lung cancer A549 cells. Methods： STAT3, β-catenin, TGF-β and ZO-1 mRNA expression were detected by real-time PCR. Endostatin and TGF-β expression were detected by immunofluorescence assay. STAT3 and β-catenin protein expression were detected by western blot. Results： Compared with the control group, TGF-β, STAT3 and β-catenin expression were down-regulated, endostatin and ZO-1 expression were up-regulated by sotetsuflavone. Simultaneously, it showed a significant concentration-dependent. Conclusion： The mechanism of action of sotetsuflavone in the treatment of lung cancer may be via inhibiting the expression of TGF-β, STAT3, and β-catenin, increasing the expression of endostatin and ZO-1, thereby exerting an anti-tumor effect.展开更多
目的了解吉安市中学生的营养状况及其影响因素,寻找相关膳食危险因素。方法采用随机整群抽样的方法,对吉安市某中学在校800名中学生开展食物频率表膳食调查和一般情况调查,回收有效问卷信息进行分析。结果体重指数(BMI,Body Mass Index...目的了解吉安市中学生的营养状况及其影响因素,寻找相关膳食危险因素。方法采用随机整群抽样的方法,对吉安市某中学在校800名中学生开展食物频率表膳食调查和一般情况调查,回收有效问卷信息进行分析。结果体重指数(BMI,Body Mass Index)低于正常值的有130人(17.24%),高于正常值的有60人(7.96%),其中男生消瘦和超重检出率分别为12.47%、6.6%,女生检出率分别为4.77%、1.33%,多因素Logistics回归分析显示,超重、肥胖的发生与奶茶摄入频次有关(P<0.05)。结论吉安市中学生存在一定的营养状况问题,且与特定的饮食习惯有关。展开更多
基金supported by the National Natural Science Foundation of China(Nos.62105167,62075188,and 61974078)the Natural Science Foundation of Zhejiang Province(Nos.LQ22F050008 and LY21F050007)+1 种基金the Natural Science Foundation of Ningbo(Nos.2021J074 and 2021J059)the Key Research and Development Program of Jiangsu Province(No.BE2021082)。
文摘Mode splitters that directly separate modes without changing their orders are highly promising to improve the flexibility of the mode-division multiplexing systems.In this paper,we design a high-performance mode splitter on the silicon-oninsulator platform with a compact footprint of 14μm×2.5μm using an inverse design method based on shape optimization.The fabrication of this mode splitter requires only a single lithography step and exhibits good fabrication tolerances.The experimental results show that the proposed device exhibits state-of-the-art insertion loss(<0.9 dB)and cross talk(<-16 dB)over a broad bandwidth(1500-1600 nm).Furthermore,the shape optimization method used is implemented to design a dual-mode(de)multiplexer,and the experimental results fulfill the design objective,demonstrating the excellent generality of the design method in this paper.
基金Project supported by the Natural Science Basic Research Program of Shaanxi Province of China (Grant No. 2022JQ675)the Youth Innovation Team of Shaanxi Universities。
文摘Identifying influential nodes in complex networks and ranking their importance plays an important role in many fields such as public opinion analysis, marketing, epidemic prevention and control. To solve the issue of the existing node centrality measure only considering the specific statistical feature of a single dimension, a SLGC model is proposed that combines a node’s self-influence, its local neighborhood influence, and global influence to identify influential nodes in the network. The exponential function of e is introduced to measure the node’s self-influence;in the local neighborhood,the node’s one-hop neighboring nodes and two-hop neighboring nodes are considered, while the information entropy is introduced to measure the node’s local influence;the topological position of the node in the network and the shortest path between nodes are considered to measure the node’s global influence. To demonstrate the effectiveness of the proposed model, extensive comparison experiments are conducted with eight existing node centrality measures on six real network data sets using node differentiation ability experiments, susceptible–infected–recovered(SIR) model and network efficiency as evaluation criteria. The experimental results show that the method can identify influential nodes in complex networks more accurately.
文摘Objective:The aim of paper is to find ecological suitable regionalization of Melicope ptelefolia planting and provide a reference for the rational planning of Good Agricultural Practices(GAP).Methods:The natural ecological niches of Melicope ptelefolia was taken as basic point.The adaptable areas of Melicope ptelefolia was analysed throughout the whole nation by using Geographic Information System for Traditional Chinese Medicine(TCMGIS).Results:Besides the original distribbution region of Guangxi,Guangdong,Hainan,Yunnan,Fujian,Jiangxi,Hunan,Guizhou,we further found that Zhejiang,Taiwan,Hong Kong,Chongqing,Sichuan are adaptable for the growth of Melicope ptelefolia.The most suitable region is Guangxi,and the followed is Guangdong.Conclusion:The ecological suitable area of Melicope ptelefolia mainly distributes in Lingnan Region,and TCMGIS is comparatively scientific and accurate to analyze suitable areas for the growth of Melicope ptelefolia.These findings have important reference value for the introduction,cultivation and scientific planning of Melicope ptelefolia.
文摘Objective To investigate the effects of sotetsuflavone on endostatin, transforming growth factor-β （TGF-β）, signal transducers and activators of transcription 3 （STAT3）, β-catenin and zonula occludens-1 protein （ZO-1） in non-small cell lung cancer A549 cells. Methods： STAT3, β-catenin, TGF-β and ZO-1 mRNA expression were detected by real-time PCR. Endostatin and TGF-β expression were detected by immunofluorescence assay. STAT3 and β-catenin protein expression were detected by western blot. Results： Compared with the control group, TGF-β, STAT3 and β-catenin expression were down-regulated, endostatin and ZO-1 expression were up-regulated by sotetsuflavone. Simultaneously, it showed a significant concentration-dependent. Conclusion： The mechanism of action of sotetsuflavone in the treatment of lung cancer may be via inhibiting the expression of TGF-β, STAT3, and β-catenin, increasing the expression of endostatin and ZO-1, thereby exerting an anti-tumor effect.
文摘目的了解吉安市中学生的营养状况及其影响因素,寻找相关膳食危险因素。方法采用随机整群抽样的方法,对吉安市某中学在校800名中学生开展食物频率表膳食调查和一般情况调查,回收有效问卷信息进行分析。结果体重指数(BMI,Body Mass Index)低于正常值的有130人(17.24%),高于正常值的有60人(7.96%),其中男生消瘦和超重检出率分别为12.47%、6.6%,女生检出率分别为4.77%、1.33%,多因素Logistics回归分析显示,超重、肥胖的发生与奶茶摄入频次有关(P<0.05)。结论吉安市中学生存在一定的营养状况问题,且与特定的饮食习惯有关。
