Experiments were conducted to study the role of micro-electrolysis in removing chromaticity and COD and improving the biodegradability of wastewater from pharmaceutical, dye-printing and papermaking plants. Results sh...Experiments were conducted to study the role of micro-electrolysis in removing chromaticity and COD and improving the biodegradability of wastewater from pharmaceutical, dye-printing and papermaking plants. Results showed that the use of micro-electrolysis technology could remove more than 90% of chromaticity and more than 50% of COD and greatly improved the biodegradability of pharmaceutical wastewater. Lower initial pH could be advantageous to the removal of chromaticity. A retention time of 30 minutes was recommended for the process design of micro-electrolysis. For the use of micro-electrolysis in treatment of dye-printing wastewater, the removal rates of both chromaticity and COD were increased from neutral condition to acid condition for disperse blue wastewater; more than 90% of chromaticity and more than 50% of COD could be removed in neutral condition for vital red wastewater.展开更多
知识追踪任务旨在根据学生历史学习行为实时追踪学生知识水平变化,并且预测学生在未来学习表现.在学生学习过程中,学习行为与遗忘行为相互交织,学生的遗忘行为对知识追踪影响很大.为了准确建模知识追踪中学习与遗忘行为,提出一种兼顾学...知识追踪任务旨在根据学生历史学习行为实时追踪学生知识水平变化,并且预测学生在未来学习表现.在学生学习过程中,学习行为与遗忘行为相互交织,学生的遗忘行为对知识追踪影响很大.为了准确建模知识追踪中学习与遗忘行为,提出一种兼顾学习与遗忘行为的深度知识追踪模型LFKT(learning and forgetting behavior modeling for knowledge tracing).LFKT模型综合考虑了4个影响知识遗忘因素,包括学生重复学习知识点的间隔时间、重复学习知识点的次数、顺序学习间隔时间以及学生对于知识点的掌握程度.结合遗忘因素,LFKT采用深度神经网络,利用学生答题结果作为知识追踪过程中知识掌握程度的间接反馈,建模融合学习与遗忘行为的知识追踪模型.通过在真实在线教育数据集上的实验,与当前知识追踪模型相比,LFKT可以更好地追踪学生知识掌握状态,并具有较好的预测性能.展开更多
AIM:To evaluate the efficacy of centralized culture and possible influencing factors.METHODS:From January 2010 to July 2012,66452 patients with suspected Helicobacter pylori(H.pylori) infection from 26 hospitals in Zh...AIM:To evaluate the efficacy of centralized culture and possible influencing factors.METHODS:From January 2010 to July 2012,66452 patients with suspected Helicobacter pylori(H.pylori) infection from 26 hospitals in Zhejiang and Jiangsu Provinces in China underwent gastrointestinal endoscopy.Gastric mucosal biopsies were taken from the antrum for culture.These biopsies were transported under natural environmental temperature to the central laboratory in Hangzhou city and divided into three groups based on their transport time:5,24 and 48 h.The culture results were reported after 72 h and the positive culture rates were analyzed by a χ2 test.An additional 5736 biopsies from H.pylori-positive patients(5646 rapid urease test-positive and 90 14C-urease breath test-positive) were also cultured for quality control in the central laboratory setting.RESULTS:The positive culture rate was 31.66%(21036/66452) for the patient samples and 71.72%(4114/5736) for the H.pylori-positive quality control specimens.In the 5 h transport group,the positiveculture rate was 30.99%(3865/12471),and 32.84%(14960/45553) in the 24 h transport group.In contrast,the positive culture rate declined significantly in the 48 h transport group(26.25%; P < 0.001).During transportation,the average natural temperature increased from 4.67 to 29.14℃,while the positive culture rate declined from 36.67%(1462/3987) to 24.12%(1799/7459).When the temperature exceeded 24℃,the positive culture rate decreased significantly,especially in the 48 h transport group(23.17%).CONCLUSION:Transportation of specimens within 24 h and below 24℃ is reasonable and acceptable for centralized culture of multicenter H.pylori samples.展开更多
The excavation of foundation pit generates soil deformation around existing metro tunnel with shield driving method,which may lead to the deformation of tunnel lining.It is a challenge to evaluate the deformation of s...The excavation of foundation pit generates soil deformation around existing metro tunnel with shield driving method,which may lead to the deformation of tunnel lining.It is a challenge to evaluate the deformation of shield tunnel accurately and take measures to reduce the tunnel upward displacement as much as possible for geotechnical engineers.A new simplified analytical method is proposed to predict the longitudinal deformation of existing metro tunnel due to excavation unloading of adjacent foundation pit in this paper.Firstly,the additional stress of soils under vertical axisymmetric load in layered soil is obtained by using elastic multi-layer theory.Secondly,the metro tunnel is regarded as a Timoshenko beam supported by Winkler foundation so that the shear effect of tunnels can be taken into account.The additional stress acting on the tunnel due to excavation unloading in layered soil are compared with that in homogeneous soil.Additionally,the effectiveness of the analytical solution is verified via two actual cases.Moreover,parametric analysis is conducted to investigate the responses of the metro tunnel by considering such factors as the variation of subgrade coefficient,offset distance from the excavation center to tunnel longitudinal axis as well as equivalent shear stiffness.The proposed method can be used to provide theoretical basis for similar engineering project.展开更多
目的观察术前肠内免疫营养对食管癌新辅助化疗患者营养状态、免疫状况及临床结局的影响。方法选取行食管癌切除手术的患者65例,按随机表分为肠内免疫营养组(EIN组,34例)和常规饮食组(对照组,31例)。所有入组患者术前均行新辅助化疗2周期...目的观察术前肠内免疫营养对食管癌新辅助化疗患者营养状态、免疫状况及临床结局的影响。方法选取行食管癌切除手术的患者65例,按随机表分为肠内免疫营养组(EIN组,34例)和常规饮食组(对照组,31例)。所有入组患者术前均行新辅助化疗2周期,并于新辅助化疗结束后3~4周行食管癌根治术。EIN组于新辅助化疗第2疗程结束后1周开始在常规饮食基础上口服肠内免疫营养,直至术前1 d。对照组于新辅助化疗第2疗程结束后只给予常规饮食。观察2组患者新辅助化疗第2疗程结束后1周及术前1 d的体质量指数、肱三头肌皮皱厚度和上臂围。观察2组患者新辅助化疗第2疗程结束后1周、术前1 d、术后1 d、术后1周的营养及免疫指标。观察2组患者术后1 d下床活动时间完成例数、术后首次肛门排气时间、术后肠内营养相关不良反应发生例数、术后肺炎发生例数和住院时间。结果2组患者在性别、年龄、吸烟史、饮酒史、临床分期、肿瘤位置等方面比较差异无统计学意义(P>0.05)。术前1 d EIN组的体质量指数、肱三头肌皮皱厚度和上臂围与对照组相比差异有统计学意义(均P<0.05)。术前1 d EIN组营养指标和免疫指标显著上升(P<0.05);术后1 d 2组各营养指标和免疫指标均明显下降,与术前1 d相比差异有统计学意义(P<0.05);术后1周2组患者各指标较术后1 d显著上升(P<0.05)。术后1周2组指标和免疫指标相比差异有统计学意义(P<0.05)。术后下床活动完成例数EIN组较对照组明显增多,术后肠内营养相关不良反应(腹胀、腹泻)及肺炎并发症例数EIN组较对照组少,术后首次排气时间和住院时间EIN组比对照组均较短,差异有统计学意义(P<0.05)。结论对于食管癌新辅助化疗患者,术前口服肠内免疫营养,能改善患者的营养状态和免疫状况,增加患者对手术的耐受力,降低并发症的发生,促进患者的快速康复�展开更多
文摘Experiments were conducted to study the role of micro-electrolysis in removing chromaticity and COD and improving the biodegradability of wastewater from pharmaceutical, dye-printing and papermaking plants. Results showed that the use of micro-electrolysis technology could remove more than 90% of chromaticity and more than 50% of COD and greatly improved the biodegradability of pharmaceutical wastewater. Lower initial pH could be advantageous to the removal of chromaticity. A retention time of 30 minutes was recommended for the process design of micro-electrolysis. For the use of micro-electrolysis in treatment of dye-printing wastewater, the removal rates of both chromaticity and COD were increased from neutral condition to acid condition for disperse blue wastewater; more than 90% of chromaticity and more than 50% of COD could be removed in neutral condition for vital red wastewater.
文摘知识追踪任务旨在根据学生历史学习行为实时追踪学生知识水平变化,并且预测学生在未来学习表现.在学生学习过程中,学习行为与遗忘行为相互交织,学生的遗忘行为对知识追踪影响很大.为了准确建模知识追踪中学习与遗忘行为,提出一种兼顾学习与遗忘行为的深度知识追踪模型LFKT(learning and forgetting behavior modeling for knowledge tracing).LFKT模型综合考虑了4个影响知识遗忘因素,包括学生重复学习知识点的间隔时间、重复学习知识点的次数、顺序学习间隔时间以及学生对于知识点的掌握程度.结合遗忘因素,LFKT采用深度神经网络,利用学生答题结果作为知识追踪过程中知识掌握程度的间接反馈,建模融合学习与遗忘行为的知识追踪模型.通过在真实在线教育数据集上的实验,与当前知识追踪模型相比,LFKT可以更好地追踪学生知识掌握状态,并具有较好的预测性能.
基金Supported by Grants from the Science and Technology Program of Zhejiang Province China,No.2001C23140National Technology RD Program in the 12th Five-Year Plan of China,No.2012BAI06B02+3 种基金the Major Technology Project as part of"Prevention and Control of Major Infectious Diseases including AIDS and Viral Hepatitis",No.2013ZX10004216-002the National Key Scientific Instrument and Equipment Development Project,No.2012YQ180117the Medical and Health Science and Technology Plan Project of Zhejiang Province,No.2012KYB248the Science and Technology Project of Zhejiang province,No.2011C23140
文摘AIM:To evaluate the efficacy of centralized culture and possible influencing factors.METHODS:From January 2010 to July 2012,66452 patients with suspected Helicobacter pylori(H.pylori) infection from 26 hospitals in Zhejiang and Jiangsu Provinces in China underwent gastrointestinal endoscopy.Gastric mucosal biopsies were taken from the antrum for culture.These biopsies were transported under natural environmental temperature to the central laboratory in Hangzhou city and divided into three groups based on their transport time:5,24 and 48 h.The culture results were reported after 72 h and the positive culture rates were analyzed by a χ2 test.An additional 5736 biopsies from H.pylori-positive patients(5646 rapid urease test-positive and 90 14C-urease breath test-positive) were also cultured for quality control in the central laboratory setting.RESULTS:The positive culture rate was 31.66%(21036/66452) for the patient samples and 71.72%(4114/5736) for the H.pylori-positive quality control specimens.In the 5 h transport group,the positiveculture rate was 30.99%(3865/12471),and 32.84%(14960/45553) in the 24 h transport group.In contrast,the positive culture rate declined significantly in the 48 h transport group(26.25%; P < 0.001).During transportation,the average natural temperature increased from 4.67 to 29.14℃,while the positive culture rate declined from 36.67%(1462/3987) to 24.12%(1799/7459).When the temperature exceeded 24℃,the positive culture rate decreased significantly,especially in the 48 h transport group(23.17%).CONCLUSION:Transportation of specimens within 24 h and below 24℃ is reasonable and acceptable for centralized culture of multicenter H.pylori samples.
基金Project(51568006)supported by the National Natural Science Foundation of ChinaProject(2018JJA160134)supported by the Natural Science Foundation of Guangxi Province,China。
文摘The excavation of foundation pit generates soil deformation around existing metro tunnel with shield driving method,which may lead to the deformation of tunnel lining.It is a challenge to evaluate the deformation of shield tunnel accurately and take measures to reduce the tunnel upward displacement as much as possible for geotechnical engineers.A new simplified analytical method is proposed to predict the longitudinal deformation of existing metro tunnel due to excavation unloading of adjacent foundation pit in this paper.Firstly,the additional stress of soils under vertical axisymmetric load in layered soil is obtained by using elastic multi-layer theory.Secondly,the metro tunnel is regarded as a Timoshenko beam supported by Winkler foundation so that the shear effect of tunnels can be taken into account.The additional stress acting on the tunnel due to excavation unloading in layered soil are compared with that in homogeneous soil.Additionally,the effectiveness of the analytical solution is verified via two actual cases.Moreover,parametric analysis is conducted to investigate the responses of the metro tunnel by considering such factors as the variation of subgrade coefficient,offset distance from the excavation center to tunnel longitudinal axis as well as equivalent shear stiffness.The proposed method can be used to provide theoretical basis for similar engineering project.
文摘目的观察术前肠内免疫营养对食管癌新辅助化疗患者营养状态、免疫状况及临床结局的影响。方法选取行食管癌切除手术的患者65例,按随机表分为肠内免疫营养组(EIN组,34例)和常规饮食组(对照组,31例)。所有入组患者术前均行新辅助化疗2周期,并于新辅助化疗结束后3~4周行食管癌根治术。EIN组于新辅助化疗第2疗程结束后1周开始在常规饮食基础上口服肠内免疫营养,直至术前1 d。对照组于新辅助化疗第2疗程结束后只给予常规饮食。观察2组患者新辅助化疗第2疗程结束后1周及术前1 d的体质量指数、肱三头肌皮皱厚度和上臂围。观察2组患者新辅助化疗第2疗程结束后1周、术前1 d、术后1 d、术后1周的营养及免疫指标。观察2组患者术后1 d下床活动时间完成例数、术后首次肛门排气时间、术后肠内营养相关不良反应发生例数、术后肺炎发生例数和住院时间。结果2组患者在性别、年龄、吸烟史、饮酒史、临床分期、肿瘤位置等方面比较差异无统计学意义(P>0.05)。术前1 d EIN组的体质量指数、肱三头肌皮皱厚度和上臂围与对照组相比差异有统计学意义(均P<0.05)。术前1 d EIN组营养指标和免疫指标显著上升(P<0.05);术后1 d 2组各营养指标和免疫指标均明显下降,与术前1 d相比差异有统计学意义(P<0.05);术后1周2组患者各指标较术后1 d显著上升(P<0.05)。术后1周2组指标和免疫指标相比差异有统计学意义(P<0.05)。术后下床活动完成例数EIN组较对照组明显增多,术后肠内营养相关不良反应(腹胀、腹泻)及肺炎并发症例数EIN组较对照组少,术后首次排气时间和住院时间EIN组比对照组均较短,差异有统计学意义(P<0.05)。结论对于食管癌新辅助化疗患者,术前口服肠内免疫营养,能改善患者的营养状态和免疫状况,增加患者对手术的耐受力,降低并发症的发生,促进患者的快速康复�
