Brown rots of Red Fuji apples were observed in Hangzhou city (Zhengjiang Province, China). The causal agent was isolated and identified in both morphological and molecular genetic levels. The phenotype and phylogeneti...Brown rots of Red Fuji apples were observed in Hangzhou city (Zhengjiang Province, China). The causal agent was isolated and identified in both morphological and molecular genetic levels. The phenotype and phylogenetic analysis revealed that the isolate was </span><i><span style="font-family:Verdana;">Diaporthe phaseolorum</span></i><span style="font-family:Verdana;"> var. </span><i><span style="font-family:Verdana;">caulivora</span></i><span style="font-family:Verdana;">, and its pathogenicity on apple fruit was confirmed by re-inoculation experiment. To our knowledge, this is the first report of </span><i><span style="font-family:Verdana;">D. phaseolorum</span></i><span style="font-family:Verdana;"> var. </span><i><span style="font-family:Verdana;">caulivora</span></i><span style="font-family:Verdana;"> causing postharvest fruit rot on apple in China.展开更多
Antibody immunotherapy is a well-established therapeutic modality for cancer, acute viral infections （Marasco and Sui, 2007） and persistent viral infection such as HIV （Barouch et al., 2013） and HCMV （Freed et al...Antibody immunotherapy is a well-established therapeutic modality for cancer, acute viral infections （Marasco and Sui, 2007） and persistent viral infection such as HIV （Barouch et al., 2013） and HCMV （Freed et al., 2013）. To reduce immunogenicity of rodent antibodies （Abs）, approved anti-body drugs entering clinical trials are of human origin or are humanized versions of rodent antibodies （Reichert, 2008）.展开更多
文摘Brown rots of Red Fuji apples were observed in Hangzhou city (Zhengjiang Province, China). The causal agent was isolated and identified in both morphological and molecular genetic levels. The phenotype and phylogenetic analysis revealed that the isolate was </span><i><span style="font-family:Verdana;">Diaporthe phaseolorum</span></i><span style="font-family:Verdana;"> var. </span><i><span style="font-family:Verdana;">caulivora</span></i><span style="font-family:Verdana;">, and its pathogenicity on apple fruit was confirmed by re-inoculation experiment. To our knowledge, this is the first report of </span><i><span style="font-family:Verdana;">D. phaseolorum</span></i><span style="font-family:Verdana;"> var. </span><i><span style="font-family:Verdana;">caulivora</span></i><span style="font-family:Verdana;"> causing postharvest fruit rot on apple in China.
文摘Antibody immunotherapy is a well-established therapeutic modality for cancer, acute viral infections （Marasco and Sui, 2007） and persistent viral infection such as HIV （Barouch et al., 2013） and HCMV （Freed et al., 2013）. To reduce immunogenicity of rodent antibodies （Abs）, approved anti-body drugs entering clinical trials are of human origin or are humanized versions of rodent antibodies （Reichert, 2008）.
