Image bitmaps,i.e.,data containing pixels and visual perception,have been widely used in emerging applica-tions for pixel operations while consuming lots of memory space and energy.Compared with legacy DRAM(dynamic ra...Image bitmaps,i.e.,data containing pixels and visual perception,have been widely used in emerging applica-tions for pixel operations while consuming lots of memory space and energy.Compared with legacy DRAM(dynamic ran-dom access memory),non-volatile memories(NVMs)are suitable for bitmap storage due to the salient features of high density and intrinsic durability.However,writing NVMs suffers from higher energy consumption and latency compared with read accesses.Existing precise or approximate compression schemes in NVM controllers show limited performance for bitmaps due to the irregular data patterns and variance in bitmaps.We observe the pixel-level similarity when writing bitmaps due to the analogous contents in adjacent pixels.By exploiting the pixel-level similarity,we propose SimCom,an approximate similarity-aware compression scheme in the NVM module controller,to efficiently compress data for each write access on-the-fly.The idea behind SimCom is to compress continuous similar words into the pairs of base words with runs.The storage costs for small runs are further mitigated by reusing the least significant bits of base words.SimCom adaptively selects an appropriate compression mode for various bitmap formats,thus achieving an efficient trade-off be-tween quality and memory performance.We implement SimCom on GEM5/zsim with NVMain and evaluate the perfor-mance with real-world image/video workloads.Our results demonstrate the efficacy and efficiency of our SimCom with an efficient quality-performance trade-off.展开更多
目的:评估飞秒激光辅助超声乳化联合Ahmed青光眼引流阀植入术治疗合并难治性青光眼的白内障的有效性和安全性。方法:回顾性病例对照研究。2019-10/2021-10入院合并难治性青光眼的白内障患者53例53眼,依据自愿选择分为飞秒激光辅助白内...目的:评估飞秒激光辅助超声乳化联合Ahmed青光眼引流阀植入术治疗合并难治性青光眼的白内障的有效性和安全性。方法:回顾性病例对照研究。2019-10/2021-10入院合并难治性青光眼的白内障患者53例53眼,依据自愿选择分为飞秒激光辅助白内障超声乳化(FLACS)组26例26眼和常规白内障超声乳化(CPCS)组27例27眼。两组分别行FLACS和CPCS联合Ahmed青光眼引流阀植入术。比较两组患者术中超声乳化能量释放量(CDE)、有效超声时间(EPT)的差异和术前与术后抗青光眼药物数量的变化,以及术后观察不同时期(1d,1wk,1、3mo)在提高最佳矫正视力(BCVA),降低眼压、角膜内皮细胞损伤程度和手术并发症及成功率状况。结果:FLACS组术中CDE和EPT明显低于CPCS组(t=8.50、5.16;P<0.01、=0.001)。两组术后抗青光眼药物较术前均明显减少(t=9.12、7.76;P=0.011、0.016),但两组间无差异(t=1.79,P=0.082)。两组术后BCVA均较术前改善,眼压均较术前降低(P<0.05)。FLACS组在术后早期(1d,1wk)BCVA的改善较CPCS组更显著(t=9.74、8.49;P=0.008、0.012),但在术后1、3mo的BCVA改善程度并无不同(t=0.62、0.44;P=1.415、2.021)。CPCS组在术后随访不同时期的角膜内皮细胞损伤较FLACS组更明显(P<0.05)。术后随访的不同时期FLACS组和CPCS组在控制眼压方面无差异(F_(组间)=0.64,P_(组间)=0.421)。FLACS组的手术并发症发生率27%(7/26)较CPCS组89%(24/27)低(χ^(2)=20.95,P<0.01),其中角膜水肿(8%vs 41%)、前囊撕裂(0 vs 11%)在FLACS组中明显低于CPCS组,后囊破裂(0 vs 7%)、玻璃体脱出(0 vs 4%)及人工晶状体偏位(0 vs 7%)也均发生在CPCS组。但两组的治疗总成功率相近(P=28.718)。结论:飞秒激光辅助超声乳化联合Ahmed青光眼引流阀植入术可充分发挥联合手术的精准微创可控优势,帮助合并难治性青光眼的白内障患者有效降低眼压及更早获得视力恢复。展开更多
目的探讨血清心脏肌球蛋白结合蛋白C(c My BP-C)在急性心肌梗死(AMI)患者诊断中的价值。方法选择2014年3月至2015年11月心血管内科收治的AMI患者62例作为病例组,选取正常体检者60例作为对照组。采用双抗体夹心酶联免疫吸附试验(ELISA)...目的探讨血清心脏肌球蛋白结合蛋白C(c My BP-C)在急性心肌梗死(AMI)患者诊断中的价值。方法选择2014年3月至2015年11月心血管内科收治的AMI患者62例作为病例组,选取正常体检者60例作为对照组。采用双抗体夹心酶联免疫吸附试验(ELISA)法检测血清c My BP-C浓度。比较AMI组与对照组间c My BP-C、肌钙蛋白Ⅰ(c TnⅠ)、肌酸激酶同工酶(CK-MB)和肌红蛋白(Myo)浓度的差异,分析AMI组c My BP-C与c TnⅠ、CKMB和Myo的相关性,同时分析发病时间小于4 h的AMI患者入院时血清c My BP-C和c TnⅠ浓度与对照组的差异,比较急诊经皮冠状动脉介入(PCI)术后12 h与入院时血清c My BP-C和c TnⅠ的差异。结果 AMI组患者血清c My BP-C、c TnⅠ、CK-MB和Myo浓度较对照组均明显升高(P<0.05)。相关性分析显示,AMI组患者c My BP-C浓度与c TnⅠ、CK-MB和Myo浓度均存在正相关(分别为r=0.876、P<0.05;r=0.632、P<0.05和r=0.903、P<0.05)。发病时间小于4 h的AMI患者入院时血清c My BP-C浓度较对照组明显升高(P<0.05),而血清c TnⅠ浓度与对照组比较差异无统计学意义(P>0.05)。行急诊PCI术后12 h血清c My BP-C浓度较入院时明显下降,而c TnⅠ浓度较入院时明显升高(P<0.05)。结论 AMI患者入院时血清c My BP-C、c TnⅠ、CK-MB和Myo浓度较对照组均显著升高且c My BP-C浓度与c TnⅠ、CK-MB和Myo浓度均存在正相关;c My BP-C在发病4 h内即开始升高,提示c My BP-C可以作为诊断AMI的早期生化标志物。AMI患者行急诊PCI术后12 h血清c My BP-C浓度较入院时明显下降,表明c My BP-C可以作为评估PCI术效果的早期指标。展开更多
基金This work was supported in part by the National Natural Science Foundation of China under Grant Nos.62125202 and U22B2022.
文摘Image bitmaps,i.e.,data containing pixels and visual perception,have been widely used in emerging applica-tions for pixel operations while consuming lots of memory space and energy.Compared with legacy DRAM(dynamic ran-dom access memory),non-volatile memories(NVMs)are suitable for bitmap storage due to the salient features of high density and intrinsic durability.However,writing NVMs suffers from higher energy consumption and latency compared with read accesses.Existing precise or approximate compression schemes in NVM controllers show limited performance for bitmaps due to the irregular data patterns and variance in bitmaps.We observe the pixel-level similarity when writing bitmaps due to the analogous contents in adjacent pixels.By exploiting the pixel-level similarity,we propose SimCom,an approximate similarity-aware compression scheme in the NVM module controller,to efficiently compress data for each write access on-the-fly.The idea behind SimCom is to compress continuous similar words into the pairs of base words with runs.The storage costs for small runs are further mitigated by reusing the least significant bits of base words.SimCom adaptively selects an appropriate compression mode for various bitmap formats,thus achieving an efficient trade-off be-tween quality and memory performance.We implement SimCom on GEM5/zsim with NVMain and evaluate the perfor-mance with real-world image/video workloads.Our results demonstrate the efficacy and efficiency of our SimCom with an efficient quality-performance trade-off.
文摘目的:评估飞秒激光辅助超声乳化联合Ahmed青光眼引流阀植入术治疗合并难治性青光眼的白内障的有效性和安全性。方法:回顾性病例对照研究。2019-10/2021-10入院合并难治性青光眼的白内障患者53例53眼,依据自愿选择分为飞秒激光辅助白内障超声乳化(FLACS)组26例26眼和常规白内障超声乳化(CPCS)组27例27眼。两组分别行FLACS和CPCS联合Ahmed青光眼引流阀植入术。比较两组患者术中超声乳化能量释放量(CDE)、有效超声时间(EPT)的差异和术前与术后抗青光眼药物数量的变化,以及术后观察不同时期(1d,1wk,1、3mo)在提高最佳矫正视力(BCVA),降低眼压、角膜内皮细胞损伤程度和手术并发症及成功率状况。结果:FLACS组术中CDE和EPT明显低于CPCS组(t=8.50、5.16;P<0.01、=0.001)。两组术后抗青光眼药物较术前均明显减少(t=9.12、7.76;P=0.011、0.016),但两组间无差异(t=1.79,P=0.082)。两组术后BCVA均较术前改善,眼压均较术前降低(P<0.05)。FLACS组在术后早期(1d,1wk)BCVA的改善较CPCS组更显著(t=9.74、8.49;P=0.008、0.012),但在术后1、3mo的BCVA改善程度并无不同(t=0.62、0.44;P=1.415、2.021)。CPCS组在术后随访不同时期的角膜内皮细胞损伤较FLACS组更明显(P<0.05)。术后随访的不同时期FLACS组和CPCS组在控制眼压方面无差异(F_(组间)=0.64,P_(组间)=0.421)。FLACS组的手术并发症发生率27%(7/26)较CPCS组89%(24/27)低(χ^(2)=20.95,P<0.01),其中角膜水肿(8%vs 41%)、前囊撕裂(0 vs 11%)在FLACS组中明显低于CPCS组,后囊破裂(0 vs 7%)、玻璃体脱出(0 vs 4%)及人工晶状体偏位(0 vs 7%)也均发生在CPCS组。但两组的治疗总成功率相近(P=28.718)。结论:飞秒激光辅助超声乳化联合Ahmed青光眼引流阀植入术可充分发挥联合手术的精准微创可控优势,帮助合并难治性青光眼的白内障患者有效降低眼压及更早获得视力恢复。
文摘目的探讨血清心脏肌球蛋白结合蛋白C(c My BP-C)在急性心肌梗死(AMI)患者诊断中的价值。方法选择2014年3月至2015年11月心血管内科收治的AMI患者62例作为病例组,选取正常体检者60例作为对照组。采用双抗体夹心酶联免疫吸附试验(ELISA)法检测血清c My BP-C浓度。比较AMI组与对照组间c My BP-C、肌钙蛋白Ⅰ(c TnⅠ)、肌酸激酶同工酶(CK-MB)和肌红蛋白(Myo)浓度的差异,分析AMI组c My BP-C与c TnⅠ、CKMB和Myo的相关性,同时分析发病时间小于4 h的AMI患者入院时血清c My BP-C和c TnⅠ浓度与对照组的差异,比较急诊经皮冠状动脉介入(PCI)术后12 h与入院时血清c My BP-C和c TnⅠ的差异。结果 AMI组患者血清c My BP-C、c TnⅠ、CK-MB和Myo浓度较对照组均明显升高(P<0.05)。相关性分析显示,AMI组患者c My BP-C浓度与c TnⅠ、CK-MB和Myo浓度均存在正相关(分别为r=0.876、P<0.05;r=0.632、P<0.05和r=0.903、P<0.05)。发病时间小于4 h的AMI患者入院时血清c My BP-C浓度较对照组明显升高(P<0.05),而血清c TnⅠ浓度与对照组比较差异无统计学意义(P>0.05)。行急诊PCI术后12 h血清c My BP-C浓度较入院时明显下降,而c TnⅠ浓度较入院时明显升高(P<0.05)。结论 AMI患者入院时血清c My BP-C、c TnⅠ、CK-MB和Myo浓度较对照组均显著升高且c My BP-C浓度与c TnⅠ、CK-MB和Myo浓度均存在正相关;c My BP-C在发病4 h内即开始升高,提示c My BP-C可以作为诊断AMI的早期生化标志物。AMI患者行急诊PCI术后12 h血清c My BP-C浓度较入院时明显下降,表明c My BP-C可以作为评估PCI术效果的早期指标。
