A new series of bone affinity compounds were synthesized by linking emodin with 5-fluorouracil derivatives. Their bone affinities were established by hydroxyapative (HA) affinity experiment in vitro, and their cytosta...A new series of bone affinity compounds were synthesized by linking emodin with 5-fluorouracil derivatives. Their bone affinities were established by hydroxyapative (HA) affinity experiment in vitro, and their cytostatic effects were shown by the MTT assay.展开更多
MnWO_(4)/WO_(3) p-n heterojunction films were fabricated using a one-step method consisting of the plasma electrolytic oxidation(PEO)of titanium in homogeneous electrolytes containing paratungstate ions and stable wat...MnWO_(4)/WO_(3) p-n heterojunction films were fabricated using a one-step method consisting of the plasma electrolytic oxidation(PEO)of titanium in homogeneous electrolytes containing paratungstate ions and stable watersoluble EDTA-chelated manganese.The influences of the formation current density and W:Mn molar ratio of the electrolyte,which was varied from 1:2 to 2:1,on the composition,morphology,and optical and photocatalytic properties of the resulting coatings were studied.X-ray diffraction analysis,scanning electron microscopy,energy dispersive X-ray analysis,Raman spectroscopy,and ultraviolet diffuse reflectance spectroscopy were used to characterize the formed composites.Regardless of the W:Mn ratio of the electrolyte,the coatings contained crystalline t-WO_(3) and m-MnWO_(4).Depending on the formation conditions,the optical band gap energies of the composites varied from 2.63 to 3.01 eV.The largest absorption red shift and lowest band gap energy were observed in the film composite formed in an electrolyte with W:Mn=2:1,at a current density of 0.2 A cm^(−2).Composites obtained in electrolytes with W:Mn ratios of 2:1 and 1:1 exhibited photocatalytic activity in the degradation of rhodamine C and methyl orange dyes in the presence of 10 mmol L^(–1) H_(2)O_(2) under ultraviolet and visible light irradiation.The role of hydrogen peroxide in this dye degradation on PEO-coated composites under light irradiation is discussed.展开更多
Earth's the surface is often strongly inductive,consisting of a dielectric layer thickness endpoint lying on an unlimited conductor basis.Electro-magnetic wave,spreading along the surface,it appears captured diele...Earth's the surface is often strongly inductive,consisting of a dielectric layer thickness endpoint lying on an unlimited conductor basis.Electro-magnetic wave,spreading along the surface,it appears captured dielectric layer,spreading it as in the waveguide channel.Waveguide theory it is known that the spread in the waveguide can only electromagnetic waves with a discrete set of frequencies.And experience shows that the captured waveguide channel electromagnetic waves can be any frequency.The article found that this behavior is due to the fact that electromagnetic waves in free space border-dielectric layer damped height in several wavelengths.Thus the thickness of the dielectric layer becomes more effectively,and this leads to a reduction of the minimum frequency of the waveguide.A discrete set of frequencies is blurred so that cover each other.Thus,a discrete set of frequencies becomes solid,and captured waveguide channel electromagnetic waves are independent of frequency.展开更多
目的明确2例先天性心脏病（congenital heart disease，CHD）胎儿的基因组拷贝数变异（copy number variations，CNVs）的性质，探讨3q微缺失与cHD的关系。方法提取CHD胎儿脐带组织的DNA，用全基因组低覆盖度测序检测其CNVs。结果2例CH...目的明确2例先天性心脏病（congenital heart disease，CHD）胎儿的基因组拷贝数变异（copy number variations，CNVs）的性质，探讨3q微缺失与cHD的关系。方法提取CHD胎儿脐带组织的DNA，用全基因组低覆盖度测序检测其CNVs。结果2例CHD胎儿均携带3q微缺失。病例1表现为室间隔缺损、唇腭裂，携带3q29区1．66Mb的缺失，涉及3q29微缺失综合征的所有关键基因。病例2表现为主动脉骑跨、室间隔缺损，携带3q28区240kb的缺失，未发现明确与该片段相关的致病信息。结论3q29微缺失可能导致CHD、唇腭裂等多发畸形。全基因组低覆盖度测序可用于检测CNVs。展开更多
文摘A new series of bone affinity compounds were synthesized by linking emodin with 5-fluorouracil derivatives. Their bone affinities were established by hydroxyapative (HA) affinity experiment in vitro, and their cytostatic effects were shown by the MTT assay.
基金supported by the Institute of Chemistry FEB RAS State Order(Project No.FWFN(205)-2022-0001).
文摘MnWO_(4)/WO_(3) p-n heterojunction films were fabricated using a one-step method consisting of the plasma electrolytic oxidation(PEO)of titanium in homogeneous electrolytes containing paratungstate ions and stable watersoluble EDTA-chelated manganese.The influences of the formation current density and W:Mn molar ratio of the electrolyte,which was varied from 1:2 to 2:1,on the composition,morphology,and optical and photocatalytic properties of the resulting coatings were studied.X-ray diffraction analysis,scanning electron microscopy,energy dispersive X-ray analysis,Raman spectroscopy,and ultraviolet diffuse reflectance spectroscopy were used to characterize the formed composites.Regardless of the W:Mn ratio of the electrolyte,the coatings contained crystalline t-WO_(3) and m-MnWO_(4).Depending on the formation conditions,the optical band gap energies of the composites varied from 2.63 to 3.01 eV.The largest absorption red shift and lowest band gap energy were observed in the film composite formed in an electrolyte with W:Mn=2:1,at a current density of 0.2 A cm^(−2).Composites obtained in electrolytes with W:Mn ratios of 2:1 and 1:1 exhibited photocatalytic activity in the degradation of rhodamine C and methyl orange dyes in the presence of 10 mmol L^(–1) H_(2)O_(2) under ultraviolet and visible light irradiation.The role of hydrogen peroxide in this dye degradation on PEO-coated composites under light irradiation is discussed.
文摘Earth's the surface is often strongly inductive,consisting of a dielectric layer thickness endpoint lying on an unlimited conductor basis.Electro-magnetic wave,spreading along the surface,it appears captured dielectric layer,spreading it as in the waveguide channel.Waveguide theory it is known that the spread in the waveguide can only electromagnetic waves with a discrete set of frequencies.And experience shows that the captured waveguide channel electromagnetic waves can be any frequency.The article found that this behavior is due to the fact that electromagnetic waves in free space border-dielectric layer damped height in several wavelengths.Thus the thickness of the dielectric layer becomes more effectively,and this leads to a reduction of the minimum frequency of the waveguide.A discrete set of frequencies is blurred so that cover each other.Thus,a discrete set of frequencies becomes solid,and captured waveguide channel electromagnetic waves are independent of frequency.
文摘目的明确2例先天性心脏病（congenital heart disease，CHD）胎儿的基因组拷贝数变异（copy number variations，CNVs）的性质，探讨3q微缺失与cHD的关系。方法提取CHD胎儿脐带组织的DNA，用全基因组低覆盖度测序检测其CNVs。结果2例CHD胎儿均携带3q微缺失。病例1表现为室间隔缺损、唇腭裂，携带3q29区1．66Mb的缺失，涉及3q29微缺失综合征的所有关键基因。病例2表现为主动脉骑跨、室间隔缺损，携带3q28区240kb的缺失，未发现明确与该片段相关的致病信息。结论3q29微缺失可能导致CHD、唇腭裂等多发畸形。全基因组低覆盖度测序可用于检测CNVs。
