Grinding chatter is a self?induced vibration which is unfavorable to precision machining processes. This paper proposes a forecasting method for grinding state identification based on bivarition empirical mode decompo...Grinding chatter is a self?induced vibration which is unfavorable to precision machining processes. This paper proposes a forecasting method for grinding state identification based on bivarition empirical mode decomposition(BEMD) and least squares support vector machine(LSSVM), which allows the monitoring of grinding chatter over time. BEMD is a promising technique in signal processing research which involves the decomposition of two?dimen?sional signals into a series of bivarition intrinsic mode functions(BIMFs). BEMD and the extraction criterion of its true BIMFs are investigated by processing a complex?value simulation chatter signal. Then the feature vectors which are employed as an amplification for the chatter premonition are discussed. Furthermore, the methodology is tested and validated by experimental data collected from a CNC guideway grinder KD4020 X16 in Hangzhou Hangji Machine Tool Co., Ltd. The results illustrate that the BEMD is a superior method in terms of processing non?stationary and nonlinear signals. Meanwhile, the peak to peak, real?time standard deviation and instantaneous energy are proven to be e ec?tive feature vectors which reflect the di erent grinding states. Finally, a LSSVM model is established for grinding status classification based on feature vectors, giving a prediction accuracy rate of 96%.展开更多
Objective: The purpose of this meta-analysis is to determine whether plating or intramedullary nailing(IMN) for adult diaphyseal both-bone forearm fractures(BBFF) provides better clinical outcomes. Methods: MEDLINE, E...Objective: The purpose of this meta-analysis is to determine whether plating or intramedullary nailing(IMN) for adult diaphyseal both-bone forearm fractures(BBFF) provides better clinical outcomes. Methods: MEDLINE, EMBASE, Google Scholar and The Cochrane Library were comprehensively searched until July 31, 2016.Both retrospective study and prospective trails about comparison of dual IMN or hybrid fixation versus dual plating fixation in the treatment of adult diaphyseal BBFF were included. Using Rev Man5.3 software, data of functional recovery, the union time,operating time and complication was extracted for meta-analysis. Results: The pooled analysis showed similar results in the union time, functional recovery and the rates of complications, but showed a significant difference in operating time. Conclusion: This meta-analysis demonstrates similar radiographic outcomes, functional outcomes and complications with plates or IMN used in the treatment of adult diaphyseal BBFF. IMN fixation for these fractures seems to be an alternative and effective treatment with shorter operating times and minimally invasive.展开更多
Background:Acupuncture has been recommended as a nonpharmacological intervention for managing cancer-related symptoms.However,there are few bibliometric analysis-based studies concerning the overall trends and charact...Background:Acupuncture has been recommended as a nonpharmacological intervention for managing cancer-related symptoms.However,there are few bibliometric analysis-based studies concerning the overall trends and characteristics in acupuncture therapy for cancer management.This study aims to summarize the status and bibliometric characteristics of acupuncture as an intervention for cancer-related symptoms.Methods:All clinical research papers on acupuncture for the management of cancer-related symptoms published up to October 1,2020 were collected from the PubMed and Web of Science databases.Data on the included studies were extracted to reflect the following items:publication year,journal,country or region,institution,clinical indications,and acupuncture prescriptions.Characteristics were analyzed using bibliometric methods.Results:A total of 226 papers were included.The number of such publications has increased steadily since 2004.The 226 articles were published in 94 English journals,with Integrative Cancer Therapies(18 articles) and Acupuncture in Medicine(14 articles) being the most prolific.The included studies are distributed across 20 countries and regions,among which the top two are the United States of America(68 articles) and China(60 articles).The types of cancer the studies addressed include breast,gastric,head and neck,etc.Acupuncture is mainly employed in the treatment of complications and side effects,among which nausea and vomiting,pain,hot flashes,and fatigue are the most frequently treated cancer-related symptoms.Acupuncture is the most commonly used treatment therapy,and the four most frequently used acupoints used are Neiguan(内关 PC6),Sanyinjiao(三阴交 SP6),Zusanli(足三里 ST36),and Hegu(合 LI4).The specific acupuncture prescription depends on individual patients’ symptoms.Conclusion:Research on acupuncture as an adjunctive therapy for cancer-related symptoms is developing steadily,with results being reported in a growing number of mainstream medical journals.Hence,this field is expect展开更多
目的构建含粉尘螨变应原第2组分(Der f 2)基因真核表达载体,并观察其在小鼠骨髓间充质干细胞(BMSCs)中的表达。方法提取粉尘螨总RNA,采用反转录聚合酶链式反应(RT-PCR)法扩增Der f 2基因,测序鉴定后将Der f 2基因克隆入pcDNA3.0质粒中,...目的构建含粉尘螨变应原第2组分(Der f 2)基因真核表达载体,并观察其在小鼠骨髓间充质干细胞(BMSCs)中的表达。方法提取粉尘螨总RNA,采用反转录聚合酶链式反应(RT-PCR)法扩增Der f 2基因,测序鉴定后将Der f 2基因克隆入pcDNA3.0质粒中,构建真核表达载体pcDNA3.0-Der f 2。将小鼠BMSCs分3组进行实验,包括pcDNA3.0-Der f2转染组、pcDNA3.0空质粒转染组及未转染组,分别利用RT-PCR、蛋白免疫印迹法(Western blot)检测Der f 2基因及蛋白在3组BMSCs中的表达。结果扩增的Der f 2基因序列与Gen Bank的参考序列完全一致,Der f 2基因正确克隆至真核表达载体pcDNA3.0中。转染BMSCs 48 h后,RT-PCR、Western blot检测结果显示,未转染组和pcDNA3.0空质粒转染组未检测到Der f 2基因表达,pcDNA3.0-Der f 2转染组检测到特异性条带,且大小与预期相符。结论 pcDNA3.0-Der f 2真核表达载体构建成功,Der f 2的mRNA和蛋白能在小鼠BMSCs中正确表达。展开更多
基金National Natural Science Foundation of China(Grant No.51475432)Zhejiang Provincial National Natural Science Foundation of China(Grant No.LZ13E050003)State Key Program of National Natural Science of China(Grant Nos.U1234207,U1709210)
文摘Grinding chatter is a self?induced vibration which is unfavorable to precision machining processes. This paper proposes a forecasting method for grinding state identification based on bivarition empirical mode decomposition(BEMD) and least squares support vector machine(LSSVM), which allows the monitoring of grinding chatter over time. BEMD is a promising technique in signal processing research which involves the decomposition of two?dimen?sional signals into a series of bivarition intrinsic mode functions(BIMFs). BEMD and the extraction criterion of its true BIMFs are investigated by processing a complex?value simulation chatter signal. Then the feature vectors which are employed as an amplification for the chatter premonition are discussed. Furthermore, the methodology is tested and validated by experimental data collected from a CNC guideway grinder KD4020 X16 in Hangzhou Hangji Machine Tool Co., Ltd. The results illustrate that the BEMD is a superior method in terms of processing non?stationary and nonlinear signals. Meanwhile, the peak to peak, real?time standard deviation and instantaneous energy are proven to be e ec?tive feature vectors which reflect the di erent grinding states. Finally, a LSSVM model is established for grinding status classification based on feature vectors, giving a prediction accuracy rate of 96%.
文摘Objective: The purpose of this meta-analysis is to determine whether plating or intramedullary nailing(IMN) for adult diaphyseal both-bone forearm fractures(BBFF) provides better clinical outcomes. Methods: MEDLINE, EMBASE, Google Scholar and The Cochrane Library were comprehensively searched until July 31, 2016.Both retrospective study and prospective trails about comparison of dual IMN or hybrid fixation versus dual plating fixation in the treatment of adult diaphyseal BBFF were included. Using Rev Man5.3 software, data of functional recovery, the union time,operating time and complication was extracted for meta-analysis. Results: The pooled analysis showed similar results in the union time, functional recovery and the rates of complications, but showed a significant difference in operating time. Conclusion: This meta-analysis demonstrates similar radiographic outcomes, functional outcomes and complications with plates or IMN used in the treatment of adult diaphyseal BBFF. IMN fixation for these fractures seems to be an alternative and effective treatment with shorter operating times and minimally invasive.
基金Supported by the National Natural Science Foundation of China:No.81774210"Sixth Major Talent Summit" of Jiangsu Province:YY-033+2 种基金"Qing Lan Project" of Jiangsu Province 2020Jiangsu Province "333 High-level Talents Cultivating Project" 2016Innovation and Entrepreneurship Training Program for College Students of Jiangsu Province 2020。
文摘Background:Acupuncture has been recommended as a nonpharmacological intervention for managing cancer-related symptoms.However,there are few bibliometric analysis-based studies concerning the overall trends and characteristics in acupuncture therapy for cancer management.This study aims to summarize the status and bibliometric characteristics of acupuncture as an intervention for cancer-related symptoms.Methods:All clinical research papers on acupuncture for the management of cancer-related symptoms published up to October 1,2020 were collected from the PubMed and Web of Science databases.Data on the included studies were extracted to reflect the following items:publication year,journal,country or region,institution,clinical indications,and acupuncture prescriptions.Characteristics were analyzed using bibliometric methods.Results:A total of 226 papers were included.The number of such publications has increased steadily since 2004.The 226 articles were published in 94 English journals,with Integrative Cancer Therapies(18 articles) and Acupuncture in Medicine(14 articles) being the most prolific.The included studies are distributed across 20 countries and regions,among which the top two are the United States of America(68 articles) and China(60 articles).The types of cancer the studies addressed include breast,gastric,head and neck,etc.Acupuncture is mainly employed in the treatment of complications and side effects,among which nausea and vomiting,pain,hot flashes,and fatigue are the most frequently treated cancer-related symptoms.Acupuncture is the most commonly used treatment therapy,and the four most frequently used acupoints used are Neiguan(内关 PC6),Sanyinjiao(三阴交 SP6),Zusanli(足三里 ST36),and Hegu(合 LI4).The specific acupuncture prescription depends on individual patients’ symptoms.Conclusion:Research on acupuncture as an adjunctive therapy for cancer-related symptoms is developing steadily,with results being reported in a growing number of mainstream medical journals.Hence,this field is expect
文摘目的构建含粉尘螨变应原第2组分(Der f 2)基因真核表达载体,并观察其在小鼠骨髓间充质干细胞(BMSCs)中的表达。方法提取粉尘螨总RNA,采用反转录聚合酶链式反应(RT-PCR)法扩增Der f 2基因,测序鉴定后将Der f 2基因克隆入pcDNA3.0质粒中,构建真核表达载体pcDNA3.0-Der f 2。将小鼠BMSCs分3组进行实验,包括pcDNA3.0-Der f2转染组、pcDNA3.0空质粒转染组及未转染组,分别利用RT-PCR、蛋白免疫印迹法(Western blot)检测Der f 2基因及蛋白在3组BMSCs中的表达。结果扩增的Der f 2基因序列与Gen Bank的参考序列完全一致,Der f 2基因正确克隆至真核表达载体pcDNA3.0中。转染BMSCs 48 h后,RT-PCR、Western blot检测结果显示,未转染组和pcDNA3.0空质粒转染组未检测到Der f 2基因表达,pcDNA3.0-Der f 2转染组检测到特异性条带,且大小与预期相符。结论 pcDNA3.0-Der f 2真核表达载体构建成功,Der f 2的mRNA和蛋白能在小鼠BMSCs中正确表达。
