采用傅里叶变换红外光谱法对驴初乳、驴常乳、牛初乳和牛常乳的乳清蛋白二级结构进行分析,再通过基因本体论功能注释和KEGG(Kyoto Encyclopedia of Genes and Genomes)代谢通路分析其功能及差异。结果表明:驴乳和牛乳乳清蛋白的二级结...采用傅里叶变换红外光谱法对驴初乳、驴常乳、牛初乳和牛常乳的乳清蛋白二级结构进行分析,再通过基因本体论功能注释和KEGG(Kyoto Encyclopedia of Genes and Genomes)代谢通路分析其功能及差异。结果表明:驴乳和牛乳乳清蛋白的二级结构存在差异;随着泌乳期的延长,二者的乳清蛋白二级结构含量也会发生一定的变化;驴乳较牛乳参与的生物学功能和代谢通路更为丰富,且驴常乳作用最为明显,更有益于婴幼儿配方乳粉的开发与利用。展开更多
Electronic skin made of thin,soft,stretchable devices that can mimic the human skin and reconstruct the tactile sensation and perception offers great opportunities for prosthesis sensing,robotics controlling,and human...Electronic skin made of thin,soft,stretchable devices that can mimic the human skin and reconstruct the tactile sensation and perception offers great opportunities for prosthesis sensing,robotics controlling,and human-machine interfaces.Advanced materials and mechanics engineering of thin film devices has proven to be an efficient route to enable and enhance flexibility and stretchability of various electronic skins;however,the density of devices is still low owing to the limitation in existing fabrication techniques.Here,we report a high-throughput one-step process to fabricate large tactile sensing arrays with a sensor density of 25 sensors/cm^(2) for electronic skin,where the sensors are based on intrinsically stretchable piezoelectric lead zirconate titanate(PZT)elastomer.The PZT elastomer sensor arrays with great uniformity and passive-driven manner enable highresolution tactile sensing,simplify the data acquisition process,and lower the manufacturing cost.The high-throughput fabrication process provides a general platform for integrating intrinsically stretchable materials into large area,high device density soft electronics for the next-generation electronic skin.展开更多
Rupture of atherosclerotic plaques causing thrombosis is the main cause of acute coronary syndrome and ischemic strokes.Inhibition of thrombosis is one of the important tasks developing biomedical materials such as in...Rupture of atherosclerotic plaques causing thrombosis is the main cause of acute coronary syndrome and ischemic strokes.Inhibition of thrombosis is one of the important tasks developing biomedical materials such as intravascular stents and vascular grafts.Shear stress(SS)influences the formation and development of atherosclerosis.The current review focuses on the vulnerable plaques observed in the high shear stress(HSS)regions,which localizes at the proximal region of the plaque intruding into the lumen.The vascular outward remodelling occurs in the HSS region for vascular compensation and that angiogenesis is a critical factor for HSS which induces atherosclerotic vulnerable plaque formation.These results greatly challenge the established belief that low shear stress is important for expansive remodelling,which provides a new perspective for preventing the transition of stable plaques to high-risk atherosclerotic lesions.展开更多
The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international partners.The complex comprises four accelerators:a 3...The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international partners.The complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs factory.In its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs bosons.Increasing the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of magnitude.This Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering aspects.Additionally,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection procedures.Construction is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 years.The commencement of experiments and data collection could potentially be initiated in the mid-2030s.展开更多
以枸杞为原料制备枸杞汁、枸杞醋,并添加白砂糖及菊花提取液制备枸杞果醋饮料,通过单因素试验及正交试验优化枸杞果醋饮料配方,并对其感官、理化及微生物指标进行分析。结果表明,枸杞果醋饮料的最佳配方为:枸杞醋8%,枸杞汁15%,白砂糖6%...以枸杞为原料制备枸杞汁、枸杞醋,并添加白砂糖及菊花提取液制备枸杞果醋饮料,通过单因素试验及正交试验优化枸杞果醋饮料配方,并对其感官、理化及微生物指标进行分析。结果表明,枸杞果醋饮料的最佳配方为:枸杞醋8%,枸杞汁15%,白砂糖6%,菊花提取液15%。在最优配方条件下,枸杞果醋饮料感官评分为95.47分,枸杞果醋饮料口感柔和、酸甜爽口。总酸、不挥发酸及氨基酸态氮含量分别为0.66 g/100 m L、0.36 g/100 m L、0.07 g/100 m L,总糖、蛋白质、脂肪含量分别为9.62 g/100 m L、0.48 g/100 m L、0.06 g/100 m L,其理化及微生物指标均符合国家农业部标准NY/T 2987—2016《绿色食品果醋饮料》要求。展开更多
文摘采用傅里叶变换红外光谱法对驴初乳、驴常乳、牛初乳和牛常乳的乳清蛋白二级结构进行分析,再通过基因本体论功能注释和KEGG(Kyoto Encyclopedia of Genes and Genomes)代谢通路分析其功能及差异。结果表明:驴乳和牛乳乳清蛋白的二级结构存在差异;随着泌乳期的延长,二者的乳清蛋白二级结构含量也会发生一定的变化;驴乳较牛乳参与的生物学功能和代谢通路更为丰富,且驴常乳作用最为明显,更有益于婴幼儿配方乳粉的开发与利用。
基金This work was supported by the City University of Hong Kong(Grant Nos.9610423,9667199)Research Grants Council of the Hong Kong Special Administrative Region(Grant No.21210820)+2 种基金Department of Science and Technology of Sichuan Province(Grant No.2020YFH0181)Z.X.acknowledges the support from the National Natural Science Foundation of China(Grant No.12072057)Fundamental Research Funds for the Central Universities(Grant No.DUT20RC(3)032).
文摘Electronic skin made of thin,soft,stretchable devices that can mimic the human skin and reconstruct the tactile sensation and perception offers great opportunities for prosthesis sensing,robotics controlling,and human-machine interfaces.Advanced materials and mechanics engineering of thin film devices has proven to be an efficient route to enable and enhance flexibility and stretchability of various electronic skins;however,the density of devices is still low owing to the limitation in existing fabrication techniques.Here,we report a high-throughput one-step process to fabricate large tactile sensing arrays with a sensor density of 25 sensors/cm^(2) for electronic skin,where the sensors are based on intrinsically stretchable piezoelectric lead zirconate titanate(PZT)elastomer.The PZT elastomer sensor arrays with great uniformity and passive-driven manner enable highresolution tactile sensing,simplify the data acquisition process,and lower the manufacturing cost.The high-throughput fabrication process provides a general platform for integrating intrinsically stretchable materials into large area,high device density soft electronics for the next-generation electronic skin.
基金This research program was supported by grants from the National Natural Science Foundation of China(31370949,11332003,81400329 and 11372364)Chongqing Science and Technology Commission(cstc2013kjrc-ljrccj10003)as well as the Public Experiment Center of State Bioindustrial Base(Chongqing),China.
文摘Rupture of atherosclerotic plaques causing thrombosis is the main cause of acute coronary syndrome and ischemic strokes.Inhibition of thrombosis is one of the important tasks developing biomedical materials such as intravascular stents and vascular grafts.Shear stress(SS)influences the formation and development of atherosclerosis.The current review focuses on the vulnerable plaques observed in the high shear stress(HSS)regions,which localizes at the proximal region of the plaque intruding into the lumen.The vascular outward remodelling occurs in the HSS region for vascular compensation and that angiogenesis is a critical factor for HSS which induces atherosclerotic vulnerable plaque formation.These results greatly challenge the established belief that low shear stress is important for expansive remodelling,which provides a new perspective for preventing the transition of stable plaques to high-risk atherosclerotic lesions.
基金support from diverse funding sources,including the National Key Program for S&T Research and Development of the Ministry of Science and Technology(MOST),Yifang Wang's Science Studio of the Ten Thousand Talents Project,the CAS Key Foreign Cooperation Grant,the National Natural Science Foundation of China(NSFC)Beijing Municipal Science&Technology Commission,the CAS Focused Science Grant,the IHEP Innovation Grant,the CAS Lead Special Training Programthe CAS Center for Excellence in Particle Physics,the CAS International Partnership Program,and the CAS/SAFEA International Partnership Program for Creative Research Teams.
文摘The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international partners.The complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs factory.In its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs bosons.Increasing the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of magnitude.This Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering aspects.Additionally,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection procedures.Construction is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 years.The commencement of experiments and data collection could potentially be initiated in the mid-2030s.
文摘以枸杞为原料制备枸杞汁、枸杞醋,并添加白砂糖及菊花提取液制备枸杞果醋饮料,通过单因素试验及正交试验优化枸杞果醋饮料配方,并对其感官、理化及微生物指标进行分析。结果表明,枸杞果醋饮料的最佳配方为:枸杞醋8%,枸杞汁15%,白砂糖6%,菊花提取液15%。在最优配方条件下,枸杞果醋饮料感官评分为95.47分,枸杞果醋饮料口感柔和、酸甜爽口。总酸、不挥发酸及氨基酸态氮含量分别为0.66 g/100 m L、0.36 g/100 m L、0.07 g/100 m L,总糖、蛋白质、脂肪含量分别为9.62 g/100 m L、0.48 g/100 m L、0.06 g/100 m L,其理化及微生物指标均符合国家农业部标准NY/T 2987—2016《绿色食品果醋饮料》要求。
