Meteorological disasters are some of the most serious and costly natural disasters, which have larger effects on economic and social activity. Liuchun Lake is an ecotourism area in the southwest region of Zhejiang pro...Meteorological disasters are some of the most serious and costly natural disasters, which have larger effects on economic and social activity. Liuchun Lake is an ecotourism area in the southwest region of Zhejiang province, where also has experienced meteorological disasters including rainstorm and cold wave. Understanding the temporal-spatial characteristics of meteorological disasters is important for the local tourism and economic development. Based on the daily temperature and precipitation from 18 meteorological stations in the southwest of Zhejiang province during 1953-2022 and some statistical approaches, the temporal and spatial characteristics of meteorological disasters (Freezing, Rainstorm, Cold wave) are analyzed. The results indicate that 1) Rainstorm occurred frequently around the Liuchun lake, the frequency was about 8 times/a, it can also reach about 3 times/a in the other region. Freezing and cold wave (including strong cold wave and extremely cold wave) had the same spatial distribution as rainstorm, however, except for Liuchun lake, they occurred less than one time in the other regions;2) The trend of rainstorm had larger spatial difference, it increased in all the study area, but it increased more significantly around the study area than around Liuchun lake. Freezing was on the downtrend in the whole region, with 93.3% of the stations passed the 95% significant level. Cold wave also showed a declined trend, but it was insignificantly at most of the stations, only 33% of the stations passed the 90% significant level. Compared with cold wave, strong cold wave and extremely strong cold wave had weaker decline in all the regions. In general, from 1953 to 2022 rainstorm showed an increasing trend, it was the main meteorological disaster in the study area, cold wave displayed a decreasing trend, but it still occurred about 2 - 3 times/a in most regions.展开更多
Single-flux-quantum(SFQ)circuits have great potential in building cryogenic quantum-classical interfaces for scaling up superconducting quantum processors.SFQ-based quantum gates have been designed and realized.Howeve...Single-flux-quantum(SFQ)circuits have great potential in building cryogenic quantum-classical interfaces for scaling up superconducting quantum processors.SFQ-based quantum gates have been designed and realized.However,current control schemes are difficult to tune the driving strength to qubits,which restricts the gate length and usually induces leakage to unwanted levels.In this study,we design the scheme and corresponding pulse generator circuit to continuously adjust the driving strength by coupling SFQ pulses with variable intervals.This scheme not only provides a way to adjust the SFQ-based gate length,but also proposes the possibility to tune the driving strength envelope.Simulations show that our scheme can suppress leakage to unwanted levels and reduce the error of SFQ-based Clifford gates by more than an order of magnitude.展开更多
表面辅助的金属有机纳米结构因其结构稳定性和潜在应用受到广泛关注。在金属有机纳米结构中,金属原子来源于外部沉积的金属或金属表面原子。外部沉积的金属原子种类多样,取决于目标纳米结构。然而,金属表面原子受限于表面科学常用的金...表面辅助的金属有机纳米结构因其结构稳定性和潜在应用受到广泛关注。在金属有机纳米结构中,金属原子来源于外部沉积的金属或金属表面原子。外部沉积的金属原子种类多样,取决于目标纳米结构。然而,金属表面原子受限于表面科学常用的金、银和铜单晶金属表面。金属有机纳米结构大多包括Au配位或是Cu配位结构,而只有少量的用表面Ag原子构成。分子金属相互作用的进一步研究有助于预期纳米结构的精确控制形成。至于构建基元,有机分子通过M―C、M―N和M―O键与表面金属原子配位。末端炔反应或者乌尔曼耦合能够实现C―M―C节点的形成。Cu和Au原子能够与含有末端氰基或吡啶基官能团的分子配位形成N―M―N键。另外,表面Ag增原子能够通过Ag―N配位键与酞菁分子配位。然而,M―O配位键的相关研究较少。因此,我们计划使用末端羟基分子与Ag增原子配位形成金属有机配位纳米结构去研究O―Ag节点。我们通过扫描隧道显微镜利用4,4’-二羟基-1,1’:3’,1’’-三联苯分子(4,4’-dihydroxy-1,1’:3’,1’’-terphenyl,H3PH)和Ag增原子成功构筑了一系列二维有序纳米结构。在室温下,蒸镀的H3PH分子自组装形成由环氢键连接的密堆积结构。当退火温度提升到330K,一种新的纳米结构出现了,该结构由O―Ag配位键和氢键共同作用形成。进一步地提升退火温度至420K,蜂巢结构和共存的二重配位链出现,这两种结构中仅由O―Ag―O键构成。为分析金属分子反应路径和O―Ag―O键的能量势垒,我们对该体系进行密度泛函理论计算。计算结果显示,O―Ag键形成的能量势垒是1.41 eV,小于O―Ag―O节点1.85 e V的能量势垒。这也解释了分等级金属-有机纳米结构形成的原因。我们的实验结果提供了一种利用有机小分子和金属增原子来设计和构筑分等级二维纳米结构的有效方法。展开更多
背景与目的外科手术是目前治疗肺癌的主要手段,肺癌患者围术期死亡的主要原因仍是术后肺炎。已有的研究结果显示致病性气道定植菌被认为是术后肺部并发症的一个独立危险因素,本研究旨在探讨术前致病性气道定植菌的存在与术后发生肺炎的...背景与目的外科手术是目前治疗肺癌的主要手段,肺癌患者围术期死亡的主要原因仍是术后肺炎。已有的研究结果显示致病性气道定植菌被认为是术后肺部并发症的一个独立危险因素,本研究旨在探讨术前致病性气道定植菌的存在与术后发生肺炎的关系及其危险因素。方法横断面调查2014年5月至2015年1月连续收治于成都市6家三级甲等医院胸外科行手术治疗的125例非小细胞肺癌患者,术前经纤维支气管镜取气管及支气管内液细菌学标本,并检测术前血清肺表面活性蛋白D(surfactant protein D,SP-D)水平,术后肺部相关并发症进行分析。结果肺癌患者术前合并致病性气道定植菌的发生率为15.2%(19/125),以革兰氏阴性菌为主(19/22,86.36%);肺癌患者术前合并致病性气道定植菌的高危因素为:高龄(≥75岁)和长期吸烟史(吸烟指数≥400支/年);术后肺部相关并发症和术后肺炎发生率在肺癌合并致病性气道定植菌组(42.11%,26.32%)均显著高于非合并组(16.04%,6.60%)(P=0.021,P=0.019)。术前血清SP-D浓度在肺癌合并致病性气道定植菌(31.25±6.09)显著高于非合并组(28.17±5.23)(P=0.023)。并发术后肺炎患者中气道致病性定值菌发生率为41.67%(5/12),其发生率是无手术后肺炎患者的3.4倍(OR=3.363,95%CI:1.467-7.711)。结论肺癌患者合并致病性气道定植菌与术后肺炎发生密切相关,且高危险因素是高龄和长期吸烟史。展开更多
为探讨谷子(Setaria italica L.)耐旱抗逆机制,解析类受体蛋白激酶(receptor like protein kinase,RLKs)基因功能,进而为培育谷子抗逆新品种提供依据,本文以干旱处理的谷子"豫谷1号"为材料,通过i TRAQ技术筛选到1个干旱响应...为探讨谷子(Setaria italica L.)耐旱抗逆机制,解析类受体蛋白激酶(receptor like protein kinase,RLKs)基因功能,进而为培育谷子抗逆新品种提供依据,本文以干旱处理的谷子"豫谷1号"为材料,通过i TRAQ技术筛选到1个干旱响应的类受体蛋白激酶基因,命名为SiRLK35。以谷子RNA反转录的单链cDNA为模板,经PCR扩增获取SiRLK35基因全长序列。应用qRT-PCR方法,对SiRLK35在NaCl、PEG、ABA、GA、Me JA等不同处理下的表达模式进行分析。进一步构建基因原核表达载体pET28a-SiRLK35,结合斑点法对SiRLK35的抗盐能力进行初步评价。同时构建过表达载体p CAMBIA1301P-SiRLK35转化水稻,并对转基因植株抗盐能力进行检测。结果显示:胁迫及激素处理均可不同程度诱导SiRLK35基因的表达;斑点法研究结果显示,在相同NaCl浓度的LB平板上,含有SiRLK35基因的原核表达载体的大肠杆菌菌株生长状态较阴性对照好,SiRLK35具有一定的抗盐能力;获得的转SiRLK35基因水稻植株对盐胁迫的耐受性高于对照。SiRLK35基因对不同胁迫均可以产生响应,但对盐胁迫的响应较为明显,推测该基因可能在谷子的抗盐及抗逆过程中发挥作用。展开更多
文摘Meteorological disasters are some of the most serious and costly natural disasters, which have larger effects on economic and social activity. Liuchun Lake is an ecotourism area in the southwest region of Zhejiang province, where also has experienced meteorological disasters including rainstorm and cold wave. Understanding the temporal-spatial characteristics of meteorological disasters is important for the local tourism and economic development. Based on the daily temperature and precipitation from 18 meteorological stations in the southwest of Zhejiang province during 1953-2022 and some statistical approaches, the temporal and spatial characteristics of meteorological disasters (Freezing, Rainstorm, Cold wave) are analyzed. The results indicate that 1) Rainstorm occurred frequently around the Liuchun lake, the frequency was about 8 times/a, it can also reach about 3 times/a in the other region. Freezing and cold wave (including strong cold wave and extremely cold wave) had the same spatial distribution as rainstorm, however, except for Liuchun lake, they occurred less than one time in the other regions;2) The trend of rainstorm had larger spatial difference, it increased in all the study area, but it increased more significantly around the study area than around Liuchun lake. Freezing was on the downtrend in the whole region, with 93.3% of the stations passed the 95% significant level. Cold wave also showed a declined trend, but it was insignificantly at most of the stations, only 33% of the stations passed the 90% significant level. Compared with cold wave, strong cold wave and extremely strong cold wave had weaker decline in all the regions. In general, from 1953 to 2022 rainstorm showed an increasing trend, it was the main meteorological disaster in the study area, cold wave displayed a decreasing trend, but it still occurred about 2 - 3 times/a in most regions.
基金Project supported in part by the National Natural Science Foundation of China (Grant No.92065116)the Key-Area Research and Development Program of Guangdong Province,China (Grant No.2020B0303030002)+1 种基金the Shanghai Technology Innovation Action Plan Integrated Circuit Technology Support Program (Grant No.22DZ1100200)the Strategic Priority Research Program of the Chinese Academy of Sciences (Grant No.XDA18000000)。
文摘Single-flux-quantum(SFQ)circuits have great potential in building cryogenic quantum-classical interfaces for scaling up superconducting quantum processors.SFQ-based quantum gates have been designed and realized.However,current control schemes are difficult to tune the driving strength to qubits,which restricts the gate length and usually induces leakage to unwanted levels.In this study,we design the scheme and corresponding pulse generator circuit to continuously adjust the driving strength by coupling SFQ pulses with variable intervals.This scheme not only provides a way to adjust the SFQ-based gate length,but also proposes the possibility to tune the driving strength envelope.Simulations show that our scheme can suppress leakage to unwanted levels and reduce the error of SFQ-based Clifford gates by more than an order of magnitude.
基金supported by the Chinese Academy of Sciences (XDC07000000, GJJSTD20200001, QYZDB-SSWSLH005)Innovation Program for Quantum Science and Technology (2021ZD0302200)+4 种基金the National Key R&D Program of China (2018YFA0306600)Anhui Initiative in Quantum Information Technologies (AHY050000)Hefei Comprehensive National Science Centerand the Fundamental Research Funds for the Central Universitiesthe Youth Innovation Promotion Association of C hinese Academy of Sciences for the support
文摘表面辅助的金属有机纳米结构因其结构稳定性和潜在应用受到广泛关注。在金属有机纳米结构中,金属原子来源于外部沉积的金属或金属表面原子。外部沉积的金属原子种类多样,取决于目标纳米结构。然而,金属表面原子受限于表面科学常用的金、银和铜单晶金属表面。金属有机纳米结构大多包括Au配位或是Cu配位结构,而只有少量的用表面Ag原子构成。分子金属相互作用的进一步研究有助于预期纳米结构的精确控制形成。至于构建基元,有机分子通过M―C、M―N和M―O键与表面金属原子配位。末端炔反应或者乌尔曼耦合能够实现C―M―C节点的形成。Cu和Au原子能够与含有末端氰基或吡啶基官能团的分子配位形成N―M―N键。另外,表面Ag增原子能够通过Ag―N配位键与酞菁分子配位。然而,M―O配位键的相关研究较少。因此,我们计划使用末端羟基分子与Ag增原子配位形成金属有机配位纳米结构去研究O―Ag节点。我们通过扫描隧道显微镜利用4,4’-二羟基-1,1’:3’,1’’-三联苯分子(4,4’-dihydroxy-1,1’:3’,1’’-terphenyl,H3PH)和Ag增原子成功构筑了一系列二维有序纳米结构。在室温下,蒸镀的H3PH分子自组装形成由环氢键连接的密堆积结构。当退火温度提升到330K,一种新的纳米结构出现了,该结构由O―Ag配位键和氢键共同作用形成。进一步地提升退火温度至420K,蜂巢结构和共存的二重配位链出现,这两种结构中仅由O―Ag―O键构成。为分析金属分子反应路径和O―Ag―O键的能量势垒,我们对该体系进行密度泛函理论计算。计算结果显示,O―Ag键形成的能量势垒是1.41 eV,小于O―Ag―O节点1.85 e V的能量势垒。这也解释了分等级金属-有机纳米结构形成的原因。我们的实验结果提供了一种利用有机小分子和金属增原子来设计和构筑分等级二维纳米结构的有效方法。
文摘背景与目的外科手术是目前治疗肺癌的主要手段,肺癌患者围术期死亡的主要原因仍是术后肺炎。已有的研究结果显示致病性气道定植菌被认为是术后肺部并发症的一个独立危险因素,本研究旨在探讨术前致病性气道定植菌的存在与术后发生肺炎的关系及其危险因素。方法横断面调查2014年5月至2015年1月连续收治于成都市6家三级甲等医院胸外科行手术治疗的125例非小细胞肺癌患者,术前经纤维支气管镜取气管及支气管内液细菌学标本,并检测术前血清肺表面活性蛋白D(surfactant protein D,SP-D)水平,术后肺部相关并发症进行分析。结果肺癌患者术前合并致病性气道定植菌的发生率为15.2%(19/125),以革兰氏阴性菌为主(19/22,86.36%);肺癌患者术前合并致病性气道定植菌的高危因素为:高龄(≥75岁)和长期吸烟史(吸烟指数≥400支/年);术后肺部相关并发症和术后肺炎发生率在肺癌合并致病性气道定植菌组(42.11%,26.32%)均显著高于非合并组(16.04%,6.60%)(P=0.021,P=0.019)。术前血清SP-D浓度在肺癌合并致病性气道定植菌(31.25±6.09)显著高于非合并组(28.17±5.23)(P=0.023)。并发术后肺炎患者中气道致病性定值菌发生率为41.67%(5/12),其发生率是无手术后肺炎患者的3.4倍(OR=3.363,95%CI:1.467-7.711)。结论肺癌患者合并致病性气道定植菌与术后肺炎发生密切相关,且高危险因素是高龄和长期吸烟史。
文摘为探讨谷子(Setaria italica L.)耐旱抗逆机制,解析类受体蛋白激酶(receptor like protein kinase,RLKs)基因功能,进而为培育谷子抗逆新品种提供依据,本文以干旱处理的谷子"豫谷1号"为材料,通过i TRAQ技术筛选到1个干旱响应的类受体蛋白激酶基因,命名为SiRLK35。以谷子RNA反转录的单链cDNA为模板,经PCR扩增获取SiRLK35基因全长序列。应用qRT-PCR方法,对SiRLK35在NaCl、PEG、ABA、GA、Me JA等不同处理下的表达模式进行分析。进一步构建基因原核表达载体pET28a-SiRLK35,结合斑点法对SiRLK35的抗盐能力进行初步评价。同时构建过表达载体p CAMBIA1301P-SiRLK35转化水稻,并对转基因植株抗盐能力进行检测。结果显示:胁迫及激素处理均可不同程度诱导SiRLK35基因的表达;斑点法研究结果显示,在相同NaCl浓度的LB平板上,含有SiRLK35基因的原核表达载体的大肠杆菌菌株生长状态较阴性对照好,SiRLK35具有一定的抗盐能力;获得的转SiRLK35基因水稻植株对盐胁迫的耐受性高于对照。SiRLK35基因对不同胁迫均可以产生响应,但对盐胁迫的响应较为明显,推测该基因可能在谷子的抗盐及抗逆过程中发挥作用。
