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Synergistic Effect of a Selective Serotonin Reuptake Inhibitor and a Selective Cyclo-Oxygenase-2 Inhibitor on Post Spinal Anesthesia Headache
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作者 Rivain Fefe Iteke David Mwembo Mutombo +7 位作者 Franck Namegabe Zirhumana Olivier Kabiriko Mukuku Emmanuel Kiyana Muyumba Tinsley Mukakala Kibonge Jean Francois Brichant Adolphe Manzanza Kilembe yapo brouh Jean Baptiste Zambeze Sakatolo Kakoma 《Pharmacology & Pharmacy》 2020年第8期196-208,共13页
<span style="font-family:Verdana;"><span style="font-family:Verdana;"><b><span style="font-family:Verdana;">Objective:</span></b></span></span... <span style="font-family:Verdana;"><span style="font-family:Verdana;"><b><span style="font-family:Verdana;">Objective:</span></b></span></span><span><span><span><span style="font-family:""><span style="font-family:Verdana;"> To evaluate the synergistic effect of a Selective Serotonin Reuptake Inhibitor (SSRI) and a Selective Cyclooxygenase 2 Inhibitor (ISCOx-2) in the management of After Rachianesthesia Headache in Obstetric Care. </span><b><span style="font-family:Verdana;">Patients and Methods:</span></b><span style="font-family:Verdana;"> This was an experimental double-blind, randomized, multi-center clinical trial of non-inferiority clinical trials over a 12-month period (May 1, 2018 to April 30, 2019) in six hospitals in southeastern DR Congo</span></span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">,</span></span></span></span><span><span><span><span style="font-family:""><span style="font-family:Verdana;"> including all patients undergoing surgery or analgesia on spinal anesthesia for obstetrical indication and with headache characteristic of a dural breccia, with no known causes, contraindications to experimental products and informed consent to been obtained. The patients were divided into four different groups depending on the protocol used, namely: Group A = Rehydration + Paracetamol, Group B = Rehydration + Celecoxib, Group C = Rehydration + Nefopam and Group 4 = Rehydration + Celecoxib + Nefopam (Study Group). Using the Statview II software, the statistical analyzes of data obtained from the different tests were made using the ANOVA test for comparing the averages of different samples using the Fisher test. Verification of the normality of the samples was made by the Kurtosis and Skewness flattening and asymmetry test. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> The protocol associating Celecoxib and Nefopam significantly demonstr 展开更多
关键词 Nefopam CELECOXIB HEADACHE Rachianesthesia OBSTETRICS
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Giant Omphalocele Ruptured: An Operated Case and Review of the Literature
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作者 Koffi Maxime Koffi Akaffou Evelyne +2 位作者 Dieth Atafy Gaudens yapo brouh da Silva-Anoma Sylvia 《Open Journal of Pediatrics》 2020年第3期447-451,共5页
<strong>Background:</strong><span style="font-family:;" "=""><span style="font-family:Verdana;"> The omphalocele is a congenital defect of closure of the abdo... <strong>Background:</strong><span style="font-family:;" "=""><span style="font-family:Verdana;"> The omphalocele is a congenital defect of closure of the abdominal wall at the level of the umbilical ring with evisceration of the intra-abdominal organs in the form of a bag covered with a membrane. This membrane can rupture and become an extreme emergency that can put the infant’s life at stake. </span><b><span style="font-family:Verdana;">Aim:</span></b><span style="font-family:Verdana;"> The purpose of this case report is to present a case of ruptured omphalocele operated successfully and describe the factors of good prognosis. </span><b><span style="font-family:Verdana;">Case Presentation:</span></b><span style="font-family:Verdana;"> A female new-born with a giant omphalocele. This omphalocele ruptured during conservative treatment. An emergency surgery was organised and the defect was closed by using a prosthesis. The postoperative course was simple. During the 12 months follow-up, we have seen no complication. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> The management of ruptured omphaloceles is a surgical and anesthetic challenge. The mortality of this condition can be improved in our context by setting up well-equipped neonatal resuscitation units.</span></span> 展开更多
关键词 Ruptured Omphalocele SURGERY TANNING
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