Hyphenrones R–X(1–7), seven new polyprenylated acylphloroglucinols derivatives, were isolated from the fruits of Hypericum henryi, together with eight know analogues. Compounds 1 and 2 were elucidated to possess com...Hyphenrones R–X(1–7), seven new polyprenylated acylphloroglucinols derivatives, were isolated from the fruits of Hypericum henryi, together with eight know analogues. Compounds 1 and 2 were elucidated to possess complex caged skeleton, while compounds 3–6 shared a common 3,9-epoxy moiety deriving from the normal polyprenylated acylphloroglucinols with a bicyclo[3.3.1]nonane-2,4,9-trione core. The new structures were elucidated on the basis of the interpretation of nuclear magnetic resonance(NMR) data, circular dichroism(CD) comparison, and single-crystal X-ray diffraction. In the bioassay, several compounds exhibited inhibitory activities against human tumor cell lines in vitro.展开更多
以四川雅安百年细叶楠(Phoebe hui Cheng ex Yang)活立木为研究对象,通过对木材的构造特征、细胞特征参数及其物理性能的研究和分析,为细叶楠木材的识别、鉴定和合理利用提供一定的理论参考依据。利用显微镜观察木材心边材的宏、微观构...以四川雅安百年细叶楠(Phoebe hui Cheng ex Yang)活立木为研究对象,通过对木材的构造特征、细胞特征参数及其物理性能的研究和分析,为细叶楠木材的识别、鉴定和合理利用提供一定的理论参考依据。利用显微镜观察木材心边材的宏、微观构造,用扫描电子显微镜观察超微构造,用图像分析软件测定各类细胞的解剖参数,X射线衍射仪分析木材的结晶度,参照国家标准测试木材的物理性质。结果表明:细叶楠为散孔材,材色呈黄色,心边材区分不明显,有芳香气味;生长轮明显,轮间呈深色带;管孔肉眼下可见,大小略一致;轴向薄壁组织放大镜下可见,稀疏傍管状;木射线放大镜下明显。管孔为单管孔和径列复管孔(2~3个)为主,偶见管孔团,导管内侵填体可见,为单穿孔,管间纹孔式互列。轴向薄壁组织量少,环管状,稀环管束状及轮界状,分隔木纤维常见,射线组织异形Ⅲ型或Ⅱ型。轴向薄壁组织和木射线尾部常含油细胞,细胞内及细胞间隙含有大量球状有机质内含物颗粒,木射线细胞内存在含钙结晶体。管孔数量适中,略小;导管分子长度中等,壁薄;木纤维长度中等,纤维细,壁薄;木射线密度中,短而窄。随着细叶楠树龄的增加,其木材纤维的宽度和厚度逐渐增大,纤维的定向越来越好,因此木材的力学性能增强。细叶楠木材在40 a后处于成熟期,此时木材的材性逐渐稳定,可以作为成材更好地加以开发利用。综合分析,细叶楠木材的尺寸稳定性好,不易开裂和翘曲,作为家具及室内装饰用材具有易加工、变形小等优点,但不适合用做承重构件。展开更多
基金supported by the Natural Sciences Foundation of Yunnan Province (2015FA032)Foundation of State Key Laboratory of Phytochemistry and Plant Resources in West China (P2015-ZZ07)+1 种基金the foundation from Youth Innovation Promotion Association CAS to X.W. Yang and G. Xuthe West Light Foundation of the Chinese Academy of Sciences to X.W. Yang
文摘Hyphenrones R–X(1–7), seven new polyprenylated acylphloroglucinols derivatives, were isolated from the fruits of Hypericum henryi, together with eight know analogues. Compounds 1 and 2 were elucidated to possess complex caged skeleton, while compounds 3–6 shared a common 3,9-epoxy moiety deriving from the normal polyprenylated acylphloroglucinols with a bicyclo[3.3.1]nonane-2,4,9-trione core. The new structures were elucidated on the basis of the interpretation of nuclear magnetic resonance(NMR) data, circular dichroism(CD) comparison, and single-crystal X-ray diffraction. In the bioassay, several compounds exhibited inhibitory activities against human tumor cell lines in vitro.
