The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international partners.The complex comprises four accelerators:a 3...The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international partners.The complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs factory.In its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs bosons.Increasing the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of magnitude.This Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering aspects.Additionally,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection procedures.Construction is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 years.The commencement of experiments and data collection could potentially be initiated in the mid-2030s.展开更多
目的:分析益气活血通络汤联合低剂量低分子量肝素预防深静脉血栓(DVT)形成的疗效。方法:收集90例老年股骨转子间骨折患者,预防DVT分为常规剂量低分子量肝素组(常规组)和益气活血通络汤联合低剂量低分子量肝素组(联合组),每组45例。比较...目的:分析益气活血通络汤联合低剂量低分子量肝素预防深静脉血栓(DVT)形成的疗效。方法:收集90例老年股骨转子间骨折患者,预防DVT分为常规剂量低分子量肝素组(常规组)和益气活血通络汤联合低剂量低分子量肝素组(联合组),每组45例。比较DVT形成情况、血栓弹力图R值、血红蛋白(HGB)、红细胞压积(HCT)、伤口渗血情况、中医证候积分及不良反应发生情况等。结果:两组术后3 d、术后2周血栓形成情况比较,差异无统计学意义。术后1周与术后2周联合组R值显著短于常规组(P<0.01),提示随着时间延长常规组抗凝强度大于联合组。联合组术后3 d HGB、HCT均显著高于常规组(P<0.05),术后3 d伤口渗血联合组5例显著少于常规组13例(P<0.05)。术后中医证候积分比较,差异有统计学意义(P<0.05),提示联合组抗凝同时可改善气虚症状。两组不良反应发生情况比较差异无统计学意义(P=0.833)。结论:益气活血通络汤联合低剂量低分子肝素预防DVT形成疗效确切,相比常规剂量低分子肝素出血风险更小,可降低术后伤口感染风险并改善全身情况。展开更多
基金support from diverse funding sources,including the National Key Program for S&T Research and Development of the Ministry of Science and Technology(MOST),Yifang Wang's Science Studio of the Ten Thousand Talents Project,the CAS Key Foreign Cooperation Grant,the National Natural Science Foundation of China(NSFC)Beijing Municipal Science&Technology Commission,the CAS Focused Science Grant,the IHEP Innovation Grant,the CAS Lead Special Training Programthe CAS Center for Excellence in Particle Physics,the CAS International Partnership Program,and the CAS/SAFEA International Partnership Program for Creative Research Teams.
文摘The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international partners.The complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs factory.In its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs bosons.Increasing the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of magnitude.This Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering aspects.Additionally,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection procedures.Construction is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 years.The commencement of experiments and data collection could potentially be initiated in the mid-2030s.
文摘目的:分析益气活血通络汤联合低剂量低分子量肝素预防深静脉血栓(DVT)形成的疗效。方法:收集90例老年股骨转子间骨折患者,预防DVT分为常规剂量低分子量肝素组(常规组)和益气活血通络汤联合低剂量低分子量肝素组(联合组),每组45例。比较DVT形成情况、血栓弹力图R值、血红蛋白(HGB)、红细胞压积(HCT)、伤口渗血情况、中医证候积分及不良反应发生情况等。结果:两组术后3 d、术后2周血栓形成情况比较,差异无统计学意义。术后1周与术后2周联合组R值显著短于常规组(P<0.01),提示随着时间延长常规组抗凝强度大于联合组。联合组术后3 d HGB、HCT均显著高于常规组(P<0.05),术后3 d伤口渗血联合组5例显著少于常规组13例(P<0.05)。术后中医证候积分比较,差异有统计学意义(P<0.05),提示联合组抗凝同时可改善气虚症状。两组不良反应发生情况比较差异无统计学意义(P=0.833)。结论:益气活血通络汤联合低剂量低分子肝素预防DVT形成疗效确切,相比常规剂量低分子肝素出血风险更小,可降低术后伤口感染风险并改善全身情况。