Acetol is a major light oxygenate and readily produced from staged or fast pyrolysis of lignocellulose biomass. Herein we report that acetol can be selectively converted to methyl pyruvate, an important fine chemical,...Acetol is a major light oxygenate and readily produced from staged or fast pyrolysis of lignocellulose biomass. Herein we report that acetol can be selectively converted to methyl pyruvate, an important fine chemical, through oxidative esterification over Au-based catalysts. Detailed experimental studies showed that Au on amphoteric supports with appropriate strength and balanced ratio of acid and base sites can facilitate the desired oxidative-esterification pathway without accelerating undesired aldol-condensation or Cannizzaro reactions. In particular, hydroxyapatite (with a Ca/P ratio of 1.62) supported Au achieved 87% selectivity to methyl pyruvate at an acetol conversion of 62%.展开更多
目的:观察肺段切除术与肺叶切除术对直径≤2 cm早期非小细胞肺癌(NSCLC)患者的影响。方法:收集2016年2月~2017年2月在青岛市中心医院接受肺叶切除术或肺段切除术的直径≤2 cm早期NSCLC患者的病例资料,共计110例,按照手术方式的不同分为A...目的:观察肺段切除术与肺叶切除术对直径≤2 cm早期非小细胞肺癌(NSCLC)患者的影响。方法:收集2016年2月~2017年2月在青岛市中心医院接受肺叶切除术或肺段切除术的直径≤2 cm早期NSCLC患者的病例资料,共计110例,按照手术方式的不同分为A组(肺叶切除术,51例)和B组(肺段切除术,59例)。对比两组围术期指标及并发症发生率、肺通气功能指标、免疫功能指标及中远期预后。结果:两组术中清扫淋巴结数目、并发症发生率组间对比无统计学差异(P>0.05)。B组的手术时间长于A组,住院费用高于A组,术中出血量、术后引流量少于A组,术后住院时间短于A组(P<0.05)。两组术后6个月用力肺活量(FVC)、一秒用力呼气容积(FEV1)、最大呼气流速峰值(PEF)、每分钟最大通气量(MVV)、每分钟最大通气量(TLCO)均下降,但B组高于A组(P<0.05)。两组术后7 d CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+)均下降,但B组高于A组(P<0.05),两组术后7 d CD8^(+)升高,但B组低于A组(P<0.05)。两组3年生存率、5年生存率及复发率组间对比无显著差异(P>0.05)。结论:肺段切除术可更好的保护直径≤2 cm早期NSCLC患者免疫功能和肺通气功能,但其与肺叶切除术中远期预后效果相当。展开更多
基金supported by the National Natural Science Foundation of China(91545114,91545203,and 21576227)the 985 Program of the Chemistry and Chemical Engineering disciplines of Xiamen University~~
文摘Acetol is a major light oxygenate and readily produced from staged or fast pyrolysis of lignocellulose biomass. Herein we report that acetol can be selectively converted to methyl pyruvate, an important fine chemical, through oxidative esterification over Au-based catalysts. Detailed experimental studies showed that Au on amphoteric supports with appropriate strength and balanced ratio of acid and base sites can facilitate the desired oxidative-esterification pathway without accelerating undesired aldol-condensation or Cannizzaro reactions. In particular, hydroxyapatite (with a Ca/P ratio of 1.62) supported Au achieved 87% selectivity to methyl pyruvate at an acetol conversion of 62%.
文摘目的:观察肺段切除术与肺叶切除术对直径≤2 cm早期非小细胞肺癌(NSCLC)患者的影响。方法:收集2016年2月~2017年2月在青岛市中心医院接受肺叶切除术或肺段切除术的直径≤2 cm早期NSCLC患者的病例资料,共计110例,按照手术方式的不同分为A组(肺叶切除术,51例)和B组(肺段切除术,59例)。对比两组围术期指标及并发症发生率、肺通气功能指标、免疫功能指标及中远期预后。结果:两组术中清扫淋巴结数目、并发症发生率组间对比无统计学差异(P>0.05)。B组的手术时间长于A组,住院费用高于A组,术中出血量、术后引流量少于A组,术后住院时间短于A组(P<0.05)。两组术后6个月用力肺活量(FVC)、一秒用力呼气容积(FEV1)、最大呼气流速峰值(PEF)、每分钟最大通气量(MVV)、每分钟最大通气量(TLCO)均下降,但B组高于A组(P<0.05)。两组术后7 d CD3^(+)、CD4^(+)、CD4^(+)/CD8^(+)均下降,但B组高于A组(P<0.05),两组术后7 d CD8^(+)升高,但B组低于A组(P<0.05)。两组3年生存率、5年生存率及复发率组间对比无显著差异(P>0.05)。结论:肺段切除术可更好的保护直径≤2 cm早期NSCLC患者免疫功能和肺通气功能,但其与肺叶切除术中远期预后效果相当。
