The breeding activities aimed to create a natural green cocoon variety for spring rearing with the characteristics of stable natural cocoon color,easy rearing and good silk quality.Four different lines from the excell...The breeding activities aimed to create a natural green cocoon variety for spring rearing with the characteristics of stable natural cocoon color,easy rearing and good silk quality.Four different lines from the excellent silkworm variety Jingsong×Haoyue were taken as recurrent parents,using the natural green cocoon variety G 9202 as donor parent.After other excellent parents were introduced to cross with these different lines,four new breeding materials were selected by recurrent backcross breeding.The characters of these breeding materials showed not only natural green cocoon but also excellent comprehensive traits.A naturally colored cocoon quaternary hybrid with excellent practical characters was selected based on multiple hybrids.It is suitable for spring rearing in Yangtze valley which includes Hunan Province.It was approved by Hunan Provincial Crop Variety Approval Committee and designated Xiangcailu No.1 in 2016.展开更多
Manas has been the most affluent county in Xinjiang Uygur Autonomous Region, northwest China. The per capita income reached 5,318 yuan (8.27 yuan against US dollar) in 2002. Yet some households in the county are still...Manas has been the most affluent county in Xinjiang Uygur Autonomous Region, northwest China. The per capita income reached 5,318 yuan (8.27 yuan against US dollar) in 2002. Yet some households in the county are still living in poverty. To get them rid of poverty, the county government has launched a poverty alleviation project, which has involved some 160 government institntions, enterprises, schools and other units. An official review on the project last year found that good results had been achieved in poverty alleviation. In 2002 alone, 199 households had been helped to shake off the poverty and move towards a relatively comfortable life.展开更多
Carotenoids play important and diverse roles in insects and their uptake and transport rely on carotenoid binding protein (CBP). The study excavated a cluster of CBP-like transcripts, including full CBP from all of th...Carotenoids play important and diverse roles in insects and their uptake and transport rely on carotenoid binding protein (CBP). The study excavated a cluster of CBP-like transcripts, including full CBP from all of the six yellow cocoon Bombyx strains investigated. Sequencing of 54 cDNA clones revealed 17 different types of transcripts which derived from alternative splicing of CBP gene locus. Five of the novel transcripts were similar with spatial and temporal distribution patterns to CBP, but their expression levels were relatively lower. The author disclosed two more novel alternative spliced transcripts with different transcription start sites from CBP in the 5’ UTRs as well as 11 SNP sites neighboring intron 1 after amplification and sequencing. qRT-PCR analysis gave evidence that relatively more mRNA was transcribed from A-type CBP gene than that from B-type in tissues like silk gland and midgut. Sequences of A- and B-type CBP genes were different in length of domains neighboring the 5’ UTR, thus their mRNA varied both in quantity and transcript types. The SNPs surrounding intron 1 can serve as stable markers to distinguish transcripts from the two isoforms, and they can be used for molecular marker assisted selection.展开更多
Mutual information has currently been one of the most intensivelyresearched measures. It has been proven to be accurate and effective registrationmeasure. Despite the general promising results, mutual information some...Mutual information has currently been one of the most intensivelyresearched measures. It has been proven to be accurate and effective registrationmeasure. Despite the general promising results, mutual information sometimes mightlead to misregistration because of neglecting spatial information and treating intensityvariations with undue sensitivity. In this paper, an extension of mutual informationframework was proposed in which higher-order spatial information regarding imagestructures was incorporated into the registration processing of PET and MR. Thesecond-order estimate of mutual information algorithm was applied to the registrationof seven patients. Evaluation from Vanderbilt University and our visual inspectionshowed that sub-voxel accuracy and robust results were achieved in all cases withsecond-order mutual information as the similarity measure and with Powell's multi-dimensional direction set method as optimization strategy.展开更多
AIM: To study the efficacy and safety of Fuzhenghuayu capsule (FZHY capsule, a capsule for strengthening body resistance to remove blood stasis) against liver fibrosis due to chronic hepatitis B. METHODS: Multicenter,...AIM: To study the efficacy and safety of Fuzhenghuayu capsule (FZHY capsule, a capsule for strengthening body resistance to remove blood stasis) against liver fibrosis due to chronic hepatitis B. METHODS: Multicenter, randomized, double blinded and parallel control experiment was conducted in patients (aged from 18 to 65 years) with liver fibrosis due to chronic hepatitis B. Hepatic histologic changes and HBV markers were examined at wk 0 and 24 during treatment. Serologic parameters (HA, LM, P-Ⅲ-P, Ⅳ-C) were determined and B ultrasound examination of the spleen and liver was performed at wk 0, 12 and 24. Liver function (liver function and serologic parameters for liver fibrosis) was observedat wk 0, 6, 12, 18 and 24. Blood and urine routine test, renal function and ECG were examined before and after treatment. RESULTS: There was no significant difference between experimental group (110 cases) and control group (106 cases) in demographic features, vital signs, course of illness, history for drug anaphylaxis and previous therapy, liver function, serologic parameters for liver fibrosis, liver histologic examination (99 cases in experimental group, 96 cases in control group), HBV markers, and renal function. According to the criteria for liver fibrosis staging, meanscore of fibrotic stage(s) in experimental group after treatment (1.80) decreased significantly compared to the previous treatment (2.33, P＜0.05), but there was no significant difference in mean score of fibrotic stage(s) (2.11 and 2.14 respectively). There was a significant difference in reverse rate between experimental group (52%) and control group (23.3%) in liver biopsy. With marked effect on decreasing the mean value of inflammatory activity and score of inflammation (P＜0.05), Fuzhenghuayu capsule had rather good effects on inhibiting inflammatory activity and was superior to that of Heluoshugan capsule. Compared to that of pretreatment, there was a significant decrease in HA, LM, P-Ⅲ-P and Ⅳ-C content in experimental group after 12 and 展开更多
基金Supported by Earmarked Fund for China Agriculture Research System(CARS-18)Hunan Provincial Science and Technology Support Program(2013NK3071)+1 种基金Natural Science Foundation of Hunan Province(2017JJ2137)Silkworm Germplasm Resources Multi-element Application Research and Development Innovation Team(2017XC01)
文摘The breeding activities aimed to create a natural green cocoon variety for spring rearing with the characteristics of stable natural cocoon color,easy rearing and good silk quality.Four different lines from the excellent silkworm variety Jingsong×Haoyue were taken as recurrent parents,using the natural green cocoon variety G 9202 as donor parent.After other excellent parents were introduced to cross with these different lines,four new breeding materials were selected by recurrent backcross breeding.The characters of these breeding materials showed not only natural green cocoon but also excellent comprehensive traits.A naturally colored cocoon quaternary hybrid with excellent practical characters was selected based on multiple hybrids.It is suitable for spring rearing in Yangtze valley which includes Hunan Province.It was approved by Hunan Provincial Crop Variety Approval Committee and designated Xiangcailu No.1 in 2016.
文摘Manas has been the most affluent county in Xinjiang Uygur Autonomous Region, northwest China. The per capita income reached 5,318 yuan (8.27 yuan against US dollar) in 2002. Yet some households in the county are still living in poverty. To get them rid of poverty, the county government has launched a poverty alleviation project, which has involved some 160 government institntions, enterprises, schools and other units. An official review on the project last year found that good results had been achieved in poverty alleviation. In 2002 alone, 199 households had been helped to shake off the poverty and move towards a relatively comfortable life.
文摘Carotenoids play important and diverse roles in insects and their uptake and transport rely on carotenoid binding protein (CBP). The study excavated a cluster of CBP-like transcripts, including full CBP from all of the six yellow cocoon Bombyx strains investigated. Sequencing of 54 cDNA clones revealed 17 different types of transcripts which derived from alternative splicing of CBP gene locus. Five of the novel transcripts were similar with spatial and temporal distribution patterns to CBP, but their expression levels were relatively lower. The author disclosed two more novel alternative spliced transcripts with different transcription start sites from CBP in the 5’ UTRs as well as 11 SNP sites neighboring intron 1 after amplification and sequencing. qRT-PCR analysis gave evidence that relatively more mRNA was transcribed from A-type CBP gene than that from B-type in tissues like silk gland and midgut. Sequences of A- and B-type CBP genes were different in length of domains neighboring the 5’ UTR, thus their mRNA varied both in quantity and transcript types. The SNPs surrounding intron 1 can serve as stable markers to distinguish transcripts from the two isoforms, and they can be used for molecular marker assisted selection.
基金The images and the standard transformation were provided as part of the project,"Retrospective Im-age Registration Evaluation"(National Institutes of Health,1 R01 CA89323),the principal investigator,J.Michael Fitzpatrick,Vanderbilt Universi
文摘Mutual information has currently been one of the most intensivelyresearched measures. It has been proven to be accurate and effective registrationmeasure. Despite the general promising results, mutual information sometimes mightlead to misregistration because of neglecting spatial information and treating intensityvariations with undue sensitivity. In this paper, an extension of mutual informationframework was proposed in which higher-order spatial information regarding imagestructures was incorporated into the registration processing of PET and MR. Thesecond-order estimate of mutual information algorithm was applied to the registrationof seven patients. Evaluation from Vanderbilt University and our visual inspectionshowed that sub-voxel accuracy and robust results were achieved in all cases withsecond-order mutual information as the similarity measure and with Powell's multi-dimensional direction set method as optimization strategy.
基金Supported by the Main Research Project of Shanghai Municipal Fund for Medical Development
文摘AIM: To study the efficacy and safety of Fuzhenghuayu capsule (FZHY capsule, a capsule for strengthening body resistance to remove blood stasis) against liver fibrosis due to chronic hepatitis B. METHODS: Multicenter, randomized, double blinded and parallel control experiment was conducted in patients (aged from 18 to 65 years) with liver fibrosis due to chronic hepatitis B. Hepatic histologic changes and HBV markers were examined at wk 0 and 24 during treatment. Serologic parameters (HA, LM, P-Ⅲ-P, Ⅳ-C) were determined and B ultrasound examination of the spleen and liver was performed at wk 0, 12 and 24. Liver function (liver function and serologic parameters for liver fibrosis) was observedat wk 0, 6, 12, 18 and 24. Blood and urine routine test, renal function and ECG were examined before and after treatment. RESULTS: There was no significant difference between experimental group (110 cases) and control group (106 cases) in demographic features, vital signs, course of illness, history for drug anaphylaxis and previous therapy, liver function, serologic parameters for liver fibrosis, liver histologic examination (99 cases in experimental group, 96 cases in control group), HBV markers, and renal function. According to the criteria for liver fibrosis staging, meanscore of fibrotic stage(s) in experimental group after treatment (1.80) decreased significantly compared to the previous treatment (2.33, P＜0.05), but there was no significant difference in mean score of fibrotic stage(s) (2.11 and 2.14 respectively). There was a significant difference in reverse rate between experimental group (52%) and control group (23.3%) in liver biopsy. With marked effect on decreasing the mean value of inflammatory activity and score of inflammation (P＜0.05), Fuzhenghuayu capsule had rather good effects on inhibiting inflammatory activity and was superior to that of Heluoshugan capsule. Compared to that of pretreatment, there was a significant decrease in HA, LM, P-Ⅲ-P and Ⅳ-C content in experimental group after 12 and
