The terahertz region is a special region of the electromagnetic spectrum that incorporates the advantages of both microwaves and infrared light waves.In the past decade,metamaterials with effective medium parameters o...The terahertz region is a special region of the electromagnetic spectrum that incorporates the advantages of both microwaves and infrared light waves.In the past decade,metamaterials with effective medium parameters or gradient phases have been studied to control terahertz waves and realize functional devices.Here,we present a new approach to manipulate terahertz waves by using coding metasurfaces that are composed of digital coding elements.We propose a general coding unit based on a Minkowski closed-loop particle that is capable of generating 1-bit coding(with two phase states of 0 and 180°),2-bit coding(with four phase states of 0,90°,180°,and 270°),and multi-bit coding elements in the terahertz frequencies by using different geometric scales.We show that multi-bit coding metasurfaces have strong abilities to control terahertz waves by designing-specific coding sequences.As an application,we demonstrate a new scattering strategy of terahertz waves—broadband and wide-angle diffusion—using a 2-bit coding metasurface with a special coding design and verify it by both numerical simulations and experiments.The presented method opens a new route to reducing the scattering of terahertz waves.展开更多
Background Mass burn casualties are always a great challenge to a medical team because a large number of seriously injured patients were sent in within a short time. Usually a high mortality is impending. Experiences ...Background Mass burn casualties are always a great challenge to a medical team because a large number of seriously injured patients were sent in within a short time. Usually a high mortality is impending. Experiences gained from successful treatment of the victims may be useful in guiding the care of mass casualties in an armed conflict. Methods Thirty-five burn victims in a single batch, being transferred nonstop by air and highway from a distant province were admitted 48 hours post-injury. All patients were male with a mean age of （22.4±8.7） years. The burn extent ranged from 4% to 75% （（13.6±12.9）%） total body surface area. Among them, thirty-two patients were complicated by moderate and severe inhalation injury, and tracheostomy had been performed in 15 patients. Decompression incisions of burn eschar on extremities were done in 17 cases before transportation. All the thirty-five patients arrived at the destination smoothly via 4-hour airlift and road transportation. Among them, twenty-five patients were in critical condition. Results These thirty-five patients were evacuated 6 hours from the scene of the injury, and they were transferred to a local hospital for primary emergency care. The patients were in very poor condition when admitted to our hospital because of the severe injury with delayed and inadequate treatment. Examination of these patients at admission showed that one patient was suffering from sepsis and multiple organ dysfunction syndrome. Dysfunction of the heart, lung, liver, kidney, and coagulation were all found in the patients. Forty-eight operations were performed in the 23 patients during one month together with comprehensive treatment, and the function of various organs was ameliorated after appropriate treatment. All the 35 patients survived. Conclusions A well-organized team consisting of several cooperative groups with specified duties is very important. As a whole, the treatment protocol should be individualized, basing on the extent of the injury and the care that the 展开更多
[目的]系统评价小切口后外侧入路与传统后外侧入路全髋关节置换术(total hip arthroplasty,THA)的临床效果.[方法]检索PubMed、Cochrane Library、EMbase、Web of Science、中国知网(CNKI)、万方数据库,查找所有比较小切口和传统THA的...[目的]系统评价小切口后外侧入路与传统后外侧入路全髋关节置换术(total hip arthroplasty,THA)的临床效果.[方法]检索PubMed、Cochrane Library、EMbase、Web of Science、中国知网(CNKI)、万方数据库,查找所有比较小切口和传统THA的随机或非随机对照试验,检索时限为2003年1月-2021年7月.按纳入排除标进行筛选、资料提取,采用RevMan 5.3软件进行荟萃分析.[结果]共纳入14篇文献,其中2篇随机对照试验,12篇队列研究.荟萃分析结果显示:小切口组切口长度(SMD=-3.78,95%CI:-4.97~-2.58,P<0.001)、术中失血量(SMD=-2.27,95%CI.-3.13~-1.40,P<0.001)、术后引流量(SMD=-6.90,95%CI:-7.57~-6.23,P<0.001)、并发症的发生(OR=0.34,95%CI:0.21~0.56,P<0.001)、外展角(SMD=-0.24,95%CI:-0.41~-0.06,P=0.007)及住院时间(SMD=-1.93,95%CI:-2.33~-1.52,P<0.001)和术后6个月髋关节Harris评分(SMD=0.87,95%CI:0.34~1.40,P=0.001)均显著优于传统入路组.而两组手术时间(SMD=0.50,95%CI:-0.20~1.19,P=0.16)和VAS评分(SMD=-0.51,95%CI:-1.31~0.29,P=0.21)的差异无统计学意义.[结论]本研究表明,小切口后外侧入路THA的临床结果优于传统后外侧入路.展开更多
BACKGROUND Functional constipation(FC)is a common and chronic gastrointestinal disease and its treatment remains challenging.AIM To evaluate the efficacy and safety of Chinese herbal medicine(CHM)on efficacy rate,glob...BACKGROUND Functional constipation(FC)is a common and chronic gastrointestinal disease and its treatment remains challenging.AIM To evaluate the efficacy and safety of Chinese herbal medicine(CHM)on efficacy rate,global symptoms,bowel movements and the Bristol Stool Scale score in patients with FC by summarizing current available randomized controlled trials(RCTs).METHODS RCTs with CHM to treat FC were identified by a systematic search of six databases from inception to October 20,2020.Two independent reviewers assessed the quality of the included articles and extracted data.Meta-analyses were performed to odds ratio(OR),mean differences(MD)and 95%confidence interval(CI)using random-effects models.Subgroup analyses and sensitivity analyses were used to explore and interpret the sources of heterogeneity.The funnel plot,Begg’s test and Egger’s test were used to detect publication bias.RESULTS Ninety-seven studies involving 8693 patients were included in this work.CHM was significantly associated with a higher efficacy rate(OR:3.62,95%CI:3.19-4.11,P<0.00001)less severe global symptoms(OR:4.03,95%CI:3.49-4.65,P<0.00001)compared with control treatment,with the low heterogeneity between studies(I2=0%,P=0.76).CHM was also associated with more frequent bowel movements(MD 0.83,95%CI:0.67-0.98,P<0.00001),a lower score on the Bristol Stool Scale(OR:1.63,95%CI:1.15-2.32,P<0.006),and a not significant recurrence rate(OR:0.47,95%CI:0.22-0.99,P=0.05).No serious adverse effects of CHM were reported.CONCLUSION In this meta-analysis,we found that CHM may have potential benefits in increasing the number of bowel movements,improving stool characteristics and alleviating global symptoms in FC patients.However,a firm conclusion could not be reached because of the poor quality of the included trials.Further trials with higher quality are required.展开更多
针对传统近邻传播聚类算法以数据点对之间的相似度作为输入度量,由于需要预设偏向参数p和阻尼系数λ,算法精度无法精确控制的问题,提出了一种跳跃跟踪麻雀搜索算法优化的交叉迭代近邻传播聚类方法.首先,针对麻雀搜索算法中发现者和加入...针对传统近邻传播聚类算法以数据点对之间的相似度作为输入度量,由于需要预设偏向参数p和阻尼系数λ,算法精度无法精确控制的问题,提出了一种跳跃跟踪麻雀搜索算法优化的交叉迭代近邻传播聚类方法.首先,针对麻雀搜索算法中发现者和加入者位置更新不足的问题,设计了一种跳跃跟踪优化策略,通过考虑偏好阻尼因子的跳跃策略设计大步长更新发现者,增加麻雀搜索算法的全局勘探能力和寻优速度,加入者设计动态小步长跟踪领头雀更新位置,同时,利用自适应种群划分机制更新发现者和加入者的比重,增加算法的后期局部开发能力和寻优速度;其次,设计基于扰动因子的Tent映射,在此基础上增加3个参数,使映射分布范围增大,并避免了陷入小周期点和不稳周期点;最后,引入轮廓系数作为评价函数,跳跃跟踪麻雀搜索算法自动寻找较优的p和λ,代替手动输入参数,并融合基于扰动因子的Tent映射优化近邻传播算法,交叉迭代确定最优簇数.使用多种算法聚类University of California Irvine数据集的10种公共数据集,仿真结果表明,本文提出的聚类算法与经典近邻传播算法、基于差分改进的仿射传播聚类算法、基于麻雀搜索算法优化的近邻传播聚类算法和进化近邻传播算法相比具有更优的搜索效率以及聚类精度.对国家信息数据进行了聚类分析,提出的方法更加准确有效合理,具有较好的应用价值.展开更多
基金This work was supported by the National High Tech Projects(2012AA030402 and 2011AA010202)the National Science Foundation of China(61138001,61171024,61171026,61371035 and 11227904)+2 种基金the 111 Project(111-2-05)the Natural Science Foundation of Jiangsu Province(BK2012019)and the 973 Program(2014CB339800).
文摘The terahertz region is a special region of the electromagnetic spectrum that incorporates the advantages of both microwaves and infrared light waves.In the past decade,metamaterials with effective medium parameters or gradient phases have been studied to control terahertz waves and realize functional devices.Here,we present a new approach to manipulate terahertz waves by using coding metasurfaces that are composed of digital coding elements.We propose a general coding unit based on a Minkowski closed-loop particle that is capable of generating 1-bit coding(with two phase states of 0 and 180°),2-bit coding(with four phase states of 0,90°,180°,and 270°),and multi-bit coding elements in the terahertz frequencies by using different geometric scales.We show that multi-bit coding metasurfaces have strong abilities to control terahertz waves by designing-specific coding sequences.As an application,we demonstrate a new scattering strategy of terahertz waves—broadband and wide-angle diffusion—using a 2-bit coding metasurface with a special coding design and verify it by both numerical simulations and experiments.The presented method opens a new route to reducing the scattering of terahertz waves.
文摘Background Mass burn casualties are always a great challenge to a medical team because a large number of seriously injured patients were sent in within a short time. Usually a high mortality is impending. Experiences gained from successful treatment of the victims may be useful in guiding the care of mass casualties in an armed conflict. Methods Thirty-five burn victims in a single batch, being transferred nonstop by air and highway from a distant province were admitted 48 hours post-injury. All patients were male with a mean age of （22.4±8.7） years. The burn extent ranged from 4% to 75% （（13.6±12.9）%） total body surface area. Among them, thirty-two patients were complicated by moderate and severe inhalation injury, and tracheostomy had been performed in 15 patients. Decompression incisions of burn eschar on extremities were done in 17 cases before transportation. All the thirty-five patients arrived at the destination smoothly via 4-hour airlift and road transportation. Among them, twenty-five patients were in critical condition. Results These thirty-five patients were evacuated 6 hours from the scene of the injury, and they were transferred to a local hospital for primary emergency care. The patients were in very poor condition when admitted to our hospital because of the severe injury with delayed and inadequate treatment. Examination of these patients at admission showed that one patient was suffering from sepsis and multiple organ dysfunction syndrome. Dysfunction of the heart, lung, liver, kidney, and coagulation were all found in the patients. Forty-eight operations were performed in the 23 patients during one month together with comprehensive treatment, and the function of various organs was ameliorated after appropriate treatment. All the 35 patients survived. Conclusions A well-organized team consisting of several cooperative groups with specified duties is very important. As a whole, the treatment protocol should be individualized, basing on the extent of the injury and the care that the
文摘[目的]系统评价小切口后外侧入路与传统后外侧入路全髋关节置换术(total hip arthroplasty,THA)的临床效果.[方法]检索PubMed、Cochrane Library、EMbase、Web of Science、中国知网(CNKI)、万方数据库,查找所有比较小切口和传统THA的随机或非随机对照试验,检索时限为2003年1月-2021年7月.按纳入排除标进行筛选、资料提取,采用RevMan 5.3软件进行荟萃分析.[结果]共纳入14篇文献,其中2篇随机对照试验,12篇队列研究.荟萃分析结果显示:小切口组切口长度(SMD=-3.78,95%CI:-4.97~-2.58,P<0.001)、术中失血量(SMD=-2.27,95%CI.-3.13~-1.40,P<0.001)、术后引流量(SMD=-6.90,95%CI:-7.57~-6.23,P<0.001)、并发症的发生(OR=0.34,95%CI:0.21~0.56,P<0.001)、外展角(SMD=-0.24,95%CI:-0.41~-0.06,P=0.007)及住院时间(SMD=-1.93,95%CI:-2.33~-1.52,P<0.001)和术后6个月髋关节Harris评分(SMD=0.87,95%CI:0.34~1.40,P=0.001)均显著优于传统入路组.而两组手术时间(SMD=0.50,95%CI:-0.20~1.19,P=0.16)和VAS评分(SMD=-0.51,95%CI:-1.31~0.29,P=0.21)的差异无统计学意义.[结论]本研究表明,小切口后外侧入路THA的临床结果优于传统后外侧入路.
基金Supported by the Hong Kong Chinese Medicine Development Fund(19B2/057A).
文摘BACKGROUND Functional constipation(FC)is a common and chronic gastrointestinal disease and its treatment remains challenging.AIM To evaluate the efficacy and safety of Chinese herbal medicine(CHM)on efficacy rate,global symptoms,bowel movements and the Bristol Stool Scale score in patients with FC by summarizing current available randomized controlled trials(RCTs).METHODS RCTs with CHM to treat FC were identified by a systematic search of six databases from inception to October 20,2020.Two independent reviewers assessed the quality of the included articles and extracted data.Meta-analyses were performed to odds ratio(OR),mean differences(MD)and 95%confidence interval(CI)using random-effects models.Subgroup analyses and sensitivity analyses were used to explore and interpret the sources of heterogeneity.The funnel plot,Begg’s test and Egger’s test were used to detect publication bias.RESULTS Ninety-seven studies involving 8693 patients were included in this work.CHM was significantly associated with a higher efficacy rate(OR:3.62,95%CI:3.19-4.11,P<0.00001)less severe global symptoms(OR:4.03,95%CI:3.49-4.65,P<0.00001)compared with control treatment,with the low heterogeneity between studies(I2=0%,P=0.76).CHM was also associated with more frequent bowel movements(MD 0.83,95%CI:0.67-0.98,P<0.00001),a lower score on the Bristol Stool Scale(OR:1.63,95%CI:1.15-2.32,P<0.006),and a not significant recurrence rate(OR:0.47,95%CI:0.22-0.99,P=0.05).No serious adverse effects of CHM were reported.CONCLUSION In this meta-analysis,we found that CHM may have potential benefits in increasing the number of bowel movements,improving stool characteristics and alleviating global symptoms in FC patients.However,a firm conclusion could not be reached because of the poor quality of the included trials.Further trials with higher quality are required.
基金National Natural Science Foundation of China(51872185)The Science and Technology Commission of Shanghai Municipality(17060502400)+3 种基金The State Key Laboratory for Modification of Chemical Fibers and Polymer Materials,Donghua University(LK1616)Academic Leaders Training Program of Pudong Health Bureau of Shanghai(PWRd2017-03)Science and Technology Development Fund of Shanghai Pudong New Area(PKJ2015-Y37)"Pu Jing" Training Program of Shanghai Pudong hospital(PJ201503)
文摘针对传统近邻传播聚类算法以数据点对之间的相似度作为输入度量,由于需要预设偏向参数p和阻尼系数λ,算法精度无法精确控制的问题,提出了一种跳跃跟踪麻雀搜索算法优化的交叉迭代近邻传播聚类方法.首先,针对麻雀搜索算法中发现者和加入者位置更新不足的问题,设计了一种跳跃跟踪优化策略,通过考虑偏好阻尼因子的跳跃策略设计大步长更新发现者,增加麻雀搜索算法的全局勘探能力和寻优速度,加入者设计动态小步长跟踪领头雀更新位置,同时,利用自适应种群划分机制更新发现者和加入者的比重,增加算法的后期局部开发能力和寻优速度;其次,设计基于扰动因子的Tent映射,在此基础上增加3个参数,使映射分布范围增大,并避免了陷入小周期点和不稳周期点;最后,引入轮廓系数作为评价函数,跳跃跟踪麻雀搜索算法自动寻找较优的p和λ,代替手动输入参数,并融合基于扰动因子的Tent映射优化近邻传播算法,交叉迭代确定最优簇数.使用多种算法聚类University of California Irvine数据集的10种公共数据集,仿真结果表明,本文提出的聚类算法与经典近邻传播算法、基于差分改进的仿射传播聚类算法、基于麻雀搜索算法优化的近邻传播聚类算法和进化近邻传播算法相比具有更优的搜索效率以及聚类精度.对国家信息数据进行了聚类分析,提出的方法更加准确有效合理,具有较好的应用价值.
