There has recently been a dramatic renewal of interest in hadron spectroscopy and charm physics. This renaissance has been driven in part by the discovery of a plethora of charmonium-like XYZ states at BESⅢ and B fac...There has recently been a dramatic renewal of interest in hadron spectroscopy and charm physics. This renaissance has been driven in part by the discovery of a plethora of charmonium-like XYZ states at BESⅢ and B factories, and the observation of an intriguing proton-antiproton threshold enhancement and the possibly related X(1835) meson state at BESⅢ, as well as the threshold measurements of charm mesons and charm baryons. We present a detailed survey of the important topics in tau-charm physics and hadron physics that can be further explored at BESⅢ during the remaining operation period of BEPCⅡ. This survey will help in the optimization of the data-taking plan over the coming years, and provides physics motivation for the possible upgrade of BEPCⅡ to higher luminosity.展开更多
Using a dedicated data sample taken in 2018 on the J/ψpeak,we perform a detailed study of the trigger efficiencies of the BESIII detector.The efficiencies are determined from three representative physics processes,na...Using a dedicated data sample taken in 2018 on the J/ψpeak,we perform a detailed study of the trigger efficiencies of the BESIII detector.The efficiencies are determined from three representative physics processes,namely Bhabha scattering,dimuon production and generic hadronic events with charged particles.The combined efficiency of all active triggers approaches 100%in most cases,with uncertainties small enough not to affect most physics analyses.展开更多
The concept of tethered satellite system （TSS） promises to revolutionize many aspects of space exploration and exploitation. It provides not only numerous possible and valuable applications, but also challenging and...The concept of tethered satellite system （TSS） promises to revolutionize many aspects of space exploration and exploitation. It provides not only numerous possible and valuable applications, but also challenging and interesting problems related to their dynamics, control, and physical implementation. Over the past decades, this exciting topic has attracted significant attention from many researchers and gained a vast number of analytical, numerical and experimental achievements with a focus on the two essential aspects of both dynamics and control. This review article presents the historic background and recent hot topics for the space tethers, and introduces the dynamics and control of TSSs in a progressive manner, from basic operating principles to the state-of-the-art achievements.展开更多
In 2018,the STAR collaboration collected data from^(96)_(44)Ru+^(96)_(44)Ru and^(96)_(40)Zr+^(96)_(40)Zr at√^(S)NN=200 Ge V to search for the presence of the chiral magnetic effect in collisions of nuclei.The isobar ...In 2018,the STAR collaboration collected data from^(96)_(44)Ru+^(96)_(44)Ru and^(96)_(40)Zr+^(96)_(40)Zr at√^(S)NN=200 Ge V to search for the presence of the chiral magnetic effect in collisions of nuclei.The isobar collision species alternated frequently between 9644 Ru+^(96)_(44)Ru and^(96)_(40)Zr+^(96)_(40)Zr.In order to conduct blind analyses of studies related to the chiral magnetic effect in these isobar data,STAR developed a three-step blind analysis procedure.Analysts are initially provided a"reference sample"of data,comprised of a mix of events from the two species,the order of which respects time-dependent changes in run conditions.After tuning analysis codes and performing time-dependent quality assurance on the reference sample,analysts are provided a species-blind sample suitable for calculating efficiencies and corrections for individual≈30-min data-taking runs.For this sample,species-specific information is disguised,but individual output files contain data from a single isobar species.Only run-by-run corrections and code alteration subsequent to these corrections are allowed at this stage.Following these modifications,the"frozen"code is passed over the fully un-blind data,completing the blind analysis.As a check of the feasibility of the blind analysis procedure,analysts completed a"mock data challenge,"analyzing data from Au+Au collisions at√^(S)NN=27 Ge V,collected in 2018.The Au+Au data were prepared in the same manner intended for the isobar blind data.The details of the blind analysis procedure and results from the mock data challenge are presented.展开更多
Using(448.1±2.9)×10^(6)ψ(3686)for the weak baryonic decayψ(3686)→Λc+∑-+c.c..The analysis procedure is optimized using a blinded method.No significant signal is observed,and the upper limit on the branch...Using(448.1±2.9)×10^(6)ψ(3686)for the weak baryonic decayψ(3686)→Λc+∑-+c.c..The analysis procedure is optimized using a blinded method.No significant signal is observed,and the upper limit on the branching fraction(B)ofψ(3686)→Λc+∑-+c.c.is set as 1.4×10^(-5)at the 90%confidence level.展开更多
Using data taken at 29 center-of-mass energies between 4.16 and 4.70 GeV with the BESⅢdetector at the Beijing Electron Positron Collider corresponding to a total integrated luminosity of approximately 18.8 fb^(-1),th...Using data taken at 29 center-of-mass energies between 4.16 and 4.70 GeV with the BESⅢdetector at the Beijing Electron Positron Collider corresponding to a total integrated luminosity of approximately 18.8 fb^(-1),the process e^(+)e^(-)→pppñπ+c.c.is observed for the first time with a statistical significance of 11.5σ.The average Born cross sections in the energy ranges of(4.160,4.380)GeV,(4.400,4.600)GeV and(4.610,4.700)GeV are measured to be(21.5±5.7±1.2)fb,(46.3±10.6±2.5)fb and(59.0±9.4±3.2)fb,respectively,where the first uncertainties are statistical and the second are systematic.The line shapes of the pñ and ppπ^(-)invariant mass spectra are consistent with phase space distributions,indicating that no hexaquark or di-baryon state is observed.展开更多
Using electron-positron annihilation data samples corresponding to an integrated luminosity of 4.5 fb-1,collected by the BESⅢdetector in the energy region between 4599.53 MeV and 4698.82 MeV,we report the first obser...Using electron-positron annihilation data samples corresponding to an integrated luminosity of 4.5 fb-1,collected by the BESⅢdetector in the energy region between 4599.53 MeV and 4698.82 MeV,we report the first observations of the Cabibbo-suppressed decaysΛ_(c)^(+)→nπ^(+)π^(0),Λ_(c)^(+)→nπ^(+)π^(-)π^(+),and the Cabibbo-favored decayΛ_(c)^(+)→nK^(-)π^(+)π^(+)with statistical significances of 7.9σ,7.8σ,and>10σ,respectively.The branching fractions of these decays are measured to be B(Λ_(c)^(+)→nπ^(+)π^(0))=(0.64±0.09±0.02)%,B(Λ_(c)^(+)→nπ^(+)π^(-)π^(+))=(0.45±0.07±0.03)%,and B(Λ_(c)^(+)→nK^(-)π^(+)π^(+))=(1.90±0.08±0.09)%,where the first uncertainties are statistical and the second are systematic.We find that the branching fraction of the decayΛ_(c)^(+)→nπ^(+)π^(0)is about one order of magnitude higher than that ofΛ_(c)^(+)→nπ^(+).展开更多
We report a search for a heavier partner of the recently observed Z_(cs)(3985)^(-) state,denoted as Z_(cs)^('-),in the process e^(+)e^(−)→K^(+)D_(s)^(∗−) D^(∗0 )+ c.c.,based on e^(*)e^(-)collision data collected ...We report a search for a heavier partner of the recently observed Z_(cs)(3985)^(-) state,denoted as Z_(cs)^('-),in the process e^(+)e^(−)→K^(+)D_(s)^(∗−) D^(∗0 )+ c.c.,based on e^(*)e^(-)collision data collected at the center-of-mass energies of √s=4.661,4.682 and 4.699 GeV with the BESIII detector.The Z_(cs)^('-) is of interest as it is expected to be a candidate for a hidden-charm and open-strange tetraquark.A partial-reconstruction technique is used to isolate K^(+)recoil-mass spectra,which are probed for a potential contribution from Z_(cs)^('-)→D_(s)^(∗−) D^(∗0 )+ c.c.We find an excess of Z_(cs)^('-)→D_(s)^(*-)-D^(*0)(c.c.)candidates with a significance of 2.1o,after considering systematic uncertainties,at a mass of(4123.5±0.7_(sat)±4.7_(syst.))MeV/c^(2).As the data set is limited in size,the upper limits are evaluated at the 90%confidence level on the product of the Born cross sections(σ^(Borm))and the branching fraction(B)of Z_(cs)^('-)→D_(s)^(*-)-D^(*0),under different assumptions of the Z_(cs)^('-) mass from 4.120 to 4.140 MeV and of the width from 10 to 50 MeV at the three center-of-mass energies.The upper limits of σ^(Born).B are found to be at the level of O(1)pb at each energy.Larger data samples are needed to confirm the Z_(cs)^('-) state and clarify its nature in the coming years.展开更多
Extracellular vesicles(EVs)are secreted by both eukaryotes and prokaryotes,and are present in all biological fluids of vertebrates,where they transfer DNA,RNA,proteins,lipids,and metabolites from donor to recipient ce...Extracellular vesicles(EVs)are secreted by both eukaryotes and prokaryotes,and are present in all biological fluids of vertebrates,where they transfer DNA,RNA,proteins,lipids,and metabolites from donor to recipient cells in cell-to-cell communication.Some EV components can also indicate the type and biological status of their parent cells and serve as diagnostic targets for liquid biopsy.EVs can also natively carry or be modified to contain therapeutic agents(e.g.,nucleic acids,proteins,polysaccharides,and small molecules)by physical,chemical,or bioengineering strategies.Due to their excellent biocompatibility and stability,EVs are ideal nanocarriers for bioactive ingredients to induce signal transduction,immunoregulation,or other therapeutic effects,which can be targeted to specific cell types.Herein,we review EV classification,intercellular communication,isolation,and characterization strategies as they apply to EV therapeutics.This review focuses on recent advances in EV applications as therapeutic carriers from in vitro research towards in vivo animal models and early clinical applications,using representative examples in the fields of cancer chemotherapeutic drug,cancer vaccine,infectious disease vaccines,regenerative medicine and gene therapy.Finally,we discuss current challenges for EV therapeutics and their future development.展开更多
From April to July 2018,a data sample at the peak energy of the T(4 S) resonance was collected with the Belle Ⅱ detector at the SuperKEKB electron-positron collider.This is the first data sample of the Belle Ⅱ exper...From April to July 2018,a data sample at the peak energy of the T(4 S) resonance was collected with the Belle Ⅱ detector at the SuperKEKB electron-positron collider.This is the first data sample of the Belle Ⅱ experiment.Using Bhabha and digamma events,we measure the integrated luminosity of the data sample to be(496.3±0.3±3.0) pb-1,where the first uncertainty is statistical and the second is systematic.This work provides a basis for future luminosity measurements at Belle Ⅱ.展开更多
High transverse momentum(pT)particle production is suppressed owing to the parton(jet)energy loss in the hot dense medium created in relativistic heavy-ion collisions.Redistribution of energy at low-to-modest pT has b...High transverse momentum(pT)particle production is suppressed owing to the parton(jet)energy loss in the hot dense medium created in relativistic heavy-ion collisions.Redistribution of energy at low-to-modest pT has been difficult to measure,owing to large anisotropic backgrounds.We report a data-driven method for background evaluation and subtraction,exploiting the away-side pseudorapidity gaps,to measure the jetlike correlation shape in Au+Au collisions at √sNN=200 GeV in the STAR experiment.The correlation shapes,for trigger particles pT>3GeV/c and various associated particle pT ranges within 0.5<pT<10GeV/c,are consistent with Gaussians,and their widths increase with centrality.The results indicate jet broadening in the medium created in central heavy-ion collisions.展开更多
The corrosion behavior of type 1045（AISI） carbon steel（CS） in oil-water fluids was investigated by considering the surface wetting state as the breakthrough point.The surface water wetting percentage（SWWP）and co...The corrosion behavior of type 1045（AISI） carbon steel（CS） in oil-water fluids was investigated by considering the surface wetting state as the breakthrough point.The surface water wetting percentage（SWWP）and corrosion weight loss of CS in different oil-water fluids were measured.The morphology and composition of the corrosion films were detected via scanning electron microscopy,electron-probe facescanning technology and Fourier-transform infrared spectroscopy.The results indicated that the corrosion weight loss of CS in the oil-water fluids corresponded with SWWP and that the corrosion process was influenced by the participation of oil.展开更多
Using inclusive decays of J/ψ aprecise determination of the number of J/ψ events collected with the BESIII detector was performed.For the two data sets taken in 2009 and 2012,the numbers of J/ψ events were recalcul...Using inclusive decays of J/ψ aprecise determination of the number of J/ψ events collected with the BESIII detector was performed.For the two data sets taken in 2009 and 2012,the numbers of J/ψ events were recalculated to be(224.0±1.3)×10^(6) and(1088.5±4.4)×10^(6),respectively;these numbers are in good agreement with the previous measurements. For the J/ψ sample taken in 2017-2019,the number of events was determined to be(8774.0±39.4)×10^(6).The total number of J/ψ events collected with the BESIII detector was determined to be(10087±44)×10^(6),where the uncertainty is dominated by systematic effects,and the statistical uncertainty is negligible.展开更多
The cross sections of e^(+)e^(-)→K^(+)K^(-)J/Ψat center-of-mass energies from 4.127 to 4.600 GeV are measured based on 15.6 fb-1data collected with the BESⅢ detector operating at the BEPCⅡ storage ring.Two resonan...The cross sections of e^(+)e^(-)→K^(+)K^(-)J/Ψat center-of-mass energies from 4.127 to 4.600 GeV are measured based on 15.6 fb-1data collected with the BESⅢ detector operating at the BEPCⅡ storage ring.Two resonant structures are observed in the line shape of the cross sections.The mass and width of the first structure are measured to be(4225.3±2.3±21.5)MeV and(72.9±6.1±30.8)MeV,respectively.They are consistent with those of the established Y(4230).The second structure is observed for the first time with a statistical significance greater than 8σ,denoted as Y(4500).Its mass and width are determined to be(4484.7±13.3±24.1)MeV and(111.1±30.1±15.2)MeV,respectively.The first presented uncertainties are statistical and the second ones are systematic.The product of the electronic partial width with the decay branching fractionΓ(Y(4230)→e^(+)e^(−))B(Y(4230)→K^(+)K^(−)J/Ψ)is reported.展开更多
The integrated luminosities of data samples collected in the BESⅢ experiment in 2016-2017 at centerof-mass energies between 4.19 and 4.28 GeV are measured with a precision better than 1% by analyzing large-angle Bhab...The integrated luminosities of data samples collected in the BESⅢ experiment in 2016-2017 at centerof-mass energies between 4.19 and 4.28 GeV are measured with a precision better than 1% by analyzing large-angle Bhabha scattering events.The integrated luminosities of old datasets collected in 2010-2014 are updated by considering corrections related to detector performance,offsetting the effect of newly discovered readout errors in the electromagnetic calorimeter,which can haphazardly occur.展开更多
From December 2019 to June 2021,the BESⅢ experiment collected approximately 5.85 fb^(−1) of data at center-of-mass energies between 4.61 and 4.95 GeV.This is the highest collision energy BEPCⅡ has reached to date.Th...From December 2019 to June 2021,the BESⅢ experiment collected approximately 5.85 fb^(−1) of data at center-of-mass energies between 4.61 and 4.95 GeV.This is the highest collision energy BEPCⅡ has reached to date.The accumulated e^(+)e^(−) annihilation data samples are useful for studying charmonium(-like)states and charmed-hadron decays.By adopting a novel method of analyzing the production of A_(c)^(+)A_(c)^(-) pairs in e^(+)e^(−) annihilation,the center-of-mass energies are measured with a precision of 0.6 MeV.Integrated luminosities are measured with a precision of better than 1% by analyzing the events of large-angle Bhabha scattering.These measurements provide important inputs to analyses based on these data samples.展开更多
During the 2016-17 and 2018-19 running periods,the BESIII experiment collected 7.5 fb of e^(+)e^(-)collision data at center-of-mass energies ranging from 4.13 to 4.44 GeV.These data samples are primarily used for the ...During the 2016-17 and 2018-19 running periods,the BESIII experiment collected 7.5 fb of e^(+)e^(-)collision data at center-of-mass energies ranging from 4.13 to 4.44 GeV.These data samples are primarily used for the study of excited charmonium and charmoniumlike states.By analyzing the di-muon process e^(+)e^(-)→(γISR=FSR)μ^(+)μ^(-),we measure the center-of-mass energies of the data samples with a precision of 0.6 MeV.Through a run-by-run study,we find that the center-of-mass energies were stable throughout most of the data-collection period.展开更多
We study the hadronic decays of ∧c+ to the final states ∑+η and ∑+η’,using an e+e-annihilation data sample of 567 pb-1 taken at a center-of-mass energy of 4.6 GeV with the BESIII detector at the BEPCⅡ collider....We study the hadronic decays of ∧c+ to the final states ∑+η and ∑+η’,using an e+e-annihilation data sample of 567 pb-1 taken at a center-of-mass energy of 4.6 GeV with the BESIII detector at the BEPCⅡ collider.We find evidence for the decays ∧c+→∑+η and ∑+η’ with statistical significance of 2.5σ and 3.2σ,respectively.Normalizing to the reference decays ∧c+→∑+π0 and ∑+ω,we obtain the ratios of the branching fractions■and ■to be 0.35±0.16±0.02 and 0.86±0.34±0.04,respectively.The upper limits at the 90% confidence level are set to be■and■.Using BESIII measurements of the branching fractions of the reference decays,we determine B（∧c+→∑+η）=（0.41±0.19±0.05）%（<0.68%）and B（∧c+→∑+η’）=（1.34±0.53 ±0.19）%（<1.9%）.Here,the first uncertainties are statistical and the second systematic.The obtained branching fraction of ∧c+→∑+η is consistent with the previous measurement,and the branching fraction of ∧c+→∑+η’ is measured for the first time.展开更多
Studies of e^+e~→D_s^+■^((*)0)K^-and the P-wave charmed-strange mesons are performed based on an e^+e^-collision data sample corresponding to an integrated luminosity of 567 pb^(-1) collected with the BESIII detecto...Studies of e^+e~→D_s^+■^((*)0)K^-and the P-wave charmed-strange mesons are performed based on an e^+e^-collision data sample corresponding to an integrated luminosity of 567 pb^(-1) collected with the BESIII detector at s^(1/2)=4.600 GeV. The processes of e^+e^-→D_s^+■^(*0)K^- and D_s^+■~0K^- are observed for the first time and are found to be dominated by the modes D_s^+D_(s1)(2536)^-and D_s^+D_(s2)~*(2573)^-, respectively. The Born cross sections are measured to be σ~B(e^+e^-→D_s^+■^(*0)K^-) =(10.1±2.3±0.8) pb and σ~B(e^+e^-→D_s^+■~0K^-) =(19.4±2.3± 1.6) pb, and the products of Born cross section and the decay branching fraction are measured to be σ~B(e^+e^-→D_s^+D_(s1)(2536)^-+c.c.)·B(D_(s1)(2536)^-→■^(*0)K^-)=(7.5±1.8±0.7) pb and σ~B(e^+e^-→D_s^+D_(s2)~*(2573)^-+ c.c.)·B(D_(s2)~*(2573)^-→■~0 K^-)=(19.7 ± 2.9 ±2.0) pb. For the D_(s1)(2536)^-and D_(s2)~*(2573)^-mesons, the masses and widths are measured to be M(D_(s1)(2536)^-)=(2537.7±0.5 ±3.1) MeV/c2, Γ(D_(s1)(2536)^-) =(1.7 ±1.2 ±0.6)MeV, and M(D_(s2)~*(2573)^-)=(2570.7±2.0 ±1.7) MeV/c^2, Γ(D_(s2)~*(2573)^-)=(17.2 ±3.6 ±1.1) MeV. The spin-parity of the D_(s2)~*(2573)^-meson is determined to be J^p= 2^+. In addition, the processes e^+e^-→D_s^+■^((*)0)K^-are searched for using the data samples taken at four(two) center-of-mass energies between 4.416(4.527) and 4.575 GeV, and upper limits at the 90% confidence level on the cross sections are determined.展开更多
Inspired by the successful application of Cas9 gene editing for“genome surgery,”we are looking back at what has been accomplished in the ten years of CRISPR editing.Intense effort is now focused on how to utilize th...Inspired by the successful application of Cas9 gene editing for“genome surgery,”we are looking back at what has been accomplished in the ten years of CRISPR editing.Intense effort is now focused on how to utilize the unique functions of CRISPR-Cas systems for molecular diagnostics and the next generation of therapeutic tools.CRISPR-Cas systems have two major advantages for gene editing that render them attractive for these new applications,specifically the ability to easily control their target recognition specificity and to couple this specificity to a targeted or secondary cleavage activity.However,despite the great potential of CRISPR/Cas for both gene editing and diagnosis,its medical applications have yet to be fully realized due factors that limit their delivery or utility for point-of-care(POC)applications.In this editorial note,we discuss how nanotechnology can address challenges associated with new CRISPR applications and what nanotechnology-specific advances are needed to circumvent remaining barriers that limit the development or use of new CRISPR/CAS-based genome editing and diagnostic approaches.展开更多
基金Supported in part by National Key Basic Research Program of China (2015CB856700)National Natural Science Foundation of China (NSFC) (11335008,11425524, 11625523, 11635010, 11735014, 11822506, 11935018)+18 种基金the Chinese Academy of Sciences (CAS) Large-Scale Scientific Facility Programthe CAS Center for Excellence in Particle Physics (CCEPP)Joint Large-Scale Scientific Facility Funds of the NSFC and CAS (U1532257, U1532258, U1732263)CAS Key Research Program of Frontier Science (QYZDJ-SSW-SLH003, QYZDJ-SSW-SLH040)100 Talents Program of CASCAS PIFIthe Thousand Talents Program of ChinaIN-PAC and Shanghai Key Laboratory for Particle Physics and CosmologyGerman Research Foundation DFG under Contracts NosCollaborative Research Center CRC 1044, FOR 2359Istituto Nazionale di Fisica Nucleare, ItalyKoninklijke Nederlandse Akademie van Wetenschappen (KNAW) (530-4CDP03)Ministry of Development of Turkey (DPT2006K-120470)National Science and Technology fundThe Knut and Alice Wallenberg Foundation (Sweden) (2016.0157)The Swedish Research CouncilU. S. Department of Energy (DE-FG02-05ER41374, DESC-0010118, DE-SC-0012069)University of Groningen (Ru G) and the Helmholtzzentrum fuer Schwerionenforschung Gmb H (GSI), Darmstadtthe Russian Ministry of Science and Higher Education (14.W03.31.0026).
文摘There has recently been a dramatic renewal of interest in hadron spectroscopy and charm physics. This renaissance has been driven in part by the discovery of a plethora of charmonium-like XYZ states at BESⅢ and B factories, and the observation of an intriguing proton-antiproton threshold enhancement and the possibly related X(1835) meson state at BESⅢ, as well as the threshold measurements of charm mesons and charm baryons. We present a detailed survey of the important topics in tau-charm physics and hadron physics that can be further explored at BESⅢ during the remaining operation period of BEPCⅡ. This survey will help in the optimization of the data-taking plan over the coming years, and provides physics motivation for the possible upgrade of BEPCⅡ to higher luminosity.
基金Supported in part by National Key Basic Research Program of China(2015CB856700)National Natural Science Foundation of China(NSFC)(11625523,11635010,11735014,11822506,11835012,11935015,11935016,11935018,11961141012)+15 种基金the Chinese Academy of Sciences(CAS)Large-Scale Scientific Facility ProgramJoint Large-Scale Scientific Facility Funds of the NSFC and CAS(U 1732263,U 1832207)CAS Key Research Program of Frontier Sciences(QYZDJ-SSWSLH003,QYZDJ-SSW-SLH040)100 Talents Program of CASINPAC and Shanghai Key Laboratory for Particle Physics and CosmologyERC(758462)German Research Foundation DFG under Contracts Nos.Collaborative Research Center CRC 1044,FOR 2359Istituto Nazionale di Fisica Nucleare,ItalyMinistry of Development o f Turkey(DPT2006K-120470)National Science and Technology fundOlle Engkvist Foundation(200-0605)STFC(United Kingdom)The Knut and Alice Wallenberg Foundation(Sweden)(2016.0157)The Royal Society,UK(DH140054,DH160214)The Swedish Research CouncilU.S.Department of Energy(DEFG02-05ER41374,DE-SC-0012069)。
文摘Using a dedicated data sample taken in 2018 on the J/ψpeak,we perform a detailed study of the trigger efficiencies of the BESIII detector.The efficiencies are determined from three representative physics processes,namely Bhabha scattering,dimuon production and generic hadronic events with charged particles.The combined efficiency of all active triggers approaches 100%in most cases,with uncertainties small enough not to affect most physics analyses.
基金the National Natural Science Foundation of China(10672073)the Innovation Fund for Graduate Students,Nanjing University of Aeronautics and Astronautics
文摘The concept of tethered satellite system （TSS） promises to revolutionize many aspects of space exploration and exploitation. It provides not only numerous possible and valuable applications, but also challenging and interesting problems related to their dynamics, control, and physical implementation. Over the past decades, this exciting topic has attracted significant attention from many researchers and gained a vast number of analytical, numerical and experimental achievements with a focus on the two essential aspects of both dynamics and control. This review article presents the historic background and recent hot topics for the space tethers, and introduces the dynamics and control of TSSs in a progressive manner, from basic operating principles to the state-of-the-art achievements.
文摘In 2018,the STAR collaboration collected data from^(96)_(44)Ru+^(96)_(44)Ru and^(96)_(40)Zr+^(96)_(40)Zr at√^(S)NN=200 Ge V to search for the presence of the chiral magnetic effect in collisions of nuclei.The isobar collision species alternated frequently between 9644 Ru+^(96)_(44)Ru and^(96)_(40)Zr+^(96)_(40)Zr.In order to conduct blind analyses of studies related to the chiral magnetic effect in these isobar data,STAR developed a three-step blind analysis procedure.Analysts are initially provided a"reference sample"of data,comprised of a mix of events from the two species,the order of which respects time-dependent changes in run conditions.After tuning analysis codes and performing time-dependent quality assurance on the reference sample,analysts are provided a species-blind sample suitable for calculating efficiencies and corrections for individual≈30-min data-taking runs.For this sample,species-specific information is disguised,but individual output files contain data from a single isobar species.Only run-by-run corrections and code alteration subsequent to these corrections are allowed at this stage.Following these modifications,the"frozen"code is passed over the fully un-blind data,completing the blind analysis.As a check of the feasibility of the blind analysis procedure,analysts completed a"mock data challenge,"analyzing data from Au+Au collisions at√^(S)NN=27 Ge V,collected in 2018.The Au+Au data were prepared in the same manner intended for the isobar blind data.The details of the blind analysis procedure and results from the mock data challenge are presented.
基金supported in part by National Key Research and Development Program of China(2020YFA0406400,2020YFA0406300)National Natural Science Foundation of China(NSFC,11975118,11635010,11735014,11835012,11935015,11935016,11935018,11961141012,12022510,12025502,12035009,12035013,12192260,12192261,12192262,12192263,12192264,12192265,12061131003)+18 种基金the Natural Science Foundation of Hunan Province of China(2019JJ30019)the Science and Technology Innovation Program of Hunan Province(2020RC3054)the Chinese Academy of Sciences(CAS)Large-Scale Scientific Facility ProgramJoint Large-Scale Scientific Facility Funds of the NSFC and CAS(U1832207)CAS Key Research Program of Frontier Sciences(QYZDJ-SSW-SLH040)100 Talents Program of CASThe Institute of Nuclear and Particle Physics(INPAC)and Shanghai Key Laboratory for Particle Physics and Cosmology,ERC(758462)European Union’s Horizon 2020 research and innovation programme under Marie Sklodowska-Curie grant agreement(894790)German Research Foundation DFG(443159800)Collaborative Research Center CRC 1044,GRK 2149Istituto Nazionale di Fisica Nucleare,ItalyMinistry of Development of Turkey(DPT2006K-120470)National Science and Technology fundNational Science Research and Innovation Fund(NSRF)via the Program Management Unit for Human Resources and Institutional Development,Research and Innovation(B16F640076)STFC(United Kingdom)Suranaree University of Technology(SUT),Thailand Science Research and Innovation(TSRI),and National Science Research and Innovation Fund(NSRF,160355)The Royal Society,UK(DH140054,DH160214)The Swedish Research CouncilU.S.Department of Energy(DE-FG02-05ER41374)。
文摘Using(448.1±2.9)×10^(6)ψ(3686)for the weak baryonic decayψ(3686)→Λc+∑-+c.c..The analysis procedure is optimized using a blinded method.No significant signal is observed,and the upper limit on the branching fraction(B)ofψ(3686)→Λc+∑-+c.c.is set as 1.4×10^(-5)at the 90%confidence level.
基金Supported in part by National Key R&D Program of China under Contracts Nos.Supported in part by National Key R&D Program of China(2020YFA0406300,2020YFA0406400)National Natural Science Foundation of China(NSFC)(11975118,11625523,11635010,11735014,11822506,11835012,11935015,11935016,11935018,11961141012,12022510,12025502,12035009,12035013,12061131003,12075252,12192260,12192261,12192262,12192263,12192264,12192265)+19 种基金the Natural Science Foundation of Hunan Province of China(2019JJ30019)the Science and Technology Innovation Program of Hunan Province(2020RC3054)the Chinese Academy of Sciences(CAS)Large-Scale Scientific Facility ProgramJoint Large-Scale Scientific Facility Funds of the NSFC and CAS(U1732263,U1832207)CAS Key Research Program of Frontier Sciences(QYZDJ-SSW-SLH040)100 Talents Program of CASINPAC and Shanghai Key Laboratory for Particle Physics and CosmologyERC(758462)European Union Horizon 2020 research and innovation programme under Contract No.Marie Sklodowska-Curie grant agreement(894790)German Research Foundation DFG(43159800)Collaborative Research Center CRC 1044,FOR 2359,GRK 2149Istituto Nazionale di Fisica Nucleare,ItalyMinistry of Development of Turkey(DPT2006K-120470)National Science and Technology fundOlle Engkvist Foundation(200-0605)STFC(United Kingdom)The Knut and Alice Wallenberg Foundation(Sweden)(2016.0157)The Royal Society,UK(DH140054,DH160214)The Swedish Research CouncilU.S.Department of Energy(DE-FG02-05ER41374,DE-SC-0012069)。
文摘Using data taken at 29 center-of-mass energies between 4.16 and 4.70 GeV with the BESⅢdetector at the Beijing Electron Positron Collider corresponding to a total integrated luminosity of approximately 18.8 fb^(-1),the process e^(+)e^(-)→pppñπ+c.c.is observed for the first time with a statistical significance of 11.5σ.The average Born cross sections in the energy ranges of(4.160,4.380)GeV,(4.400,4.600)GeV and(4.610,4.700)GeV are measured to be(21.5±5.7±1.2)fb,(46.3±10.6±2.5)fb and(59.0±9.4±3.2)fb,respectively,where the first uncertainties are statistical and the second are systematic.The line shapes of the pñ and ppπ^(-)invariant mass spectra are consistent with phase space distributions,indicating that no hexaquark or di-baryon state is observed.
基金Supported in part by National Key R&D Program of China(2020YFA0406400,2020YFA0406300)National Natural Science Foundation of China(NSFC)(11635010,11735014,11805086,11835012,11935015,11935016,11935018,11975011,11961141012,12022510,12025502,12035009,12035013,12192260,12192261,12192262,12192263,12192264,12192265)+20 种基金the Chinese Academy of Sciences(CAS)Large-Scale Scientific Facility ProgramJoint Large-Scale Scientific Facility Funds of the NSFC and CAS(U1832207)the CAS Center for Excellence in Particle Physics(CCEPP)100 Talents Program of CASFundamental Research Funds for the Central Universities,Lanzhou University,University of Chinese Academy of SciencesThe Institute of Nuclear and Particle Physics(INPAC)Shanghai Key Laboratory for Particle Physics and CosmologyERC(758462)German Research Foundation DFG(443159800)Collaborative Research Center CRC 1044,GRK 2149Istituto Nazionale di Fisica Nucleare,ItalyMinistry of Development of Turkey(DPT2006K-120470)National Science and Technology fundNational Science Research and Innovation Fund(NSRF)via the Program Management Unit for Human Resources&Institutional Development,Research and Innovation(B16F640076STFC)(United Kingdom)Suranaree University of Technology(SUT)Thailand Science Research and Innovation(TSRI)National Science Research and Innovation Fund(NSRF)(160355)The Royal Society,UK(DH140054,DH160214)The Swedish Research CouncilU.S.Department of Energy(DEFG02-05ER41374)。
文摘Using electron-positron annihilation data samples corresponding to an integrated luminosity of 4.5 fb-1,collected by the BESⅢdetector in the energy region between 4599.53 MeV and 4698.82 MeV,we report the first observations of the Cabibbo-suppressed decaysΛ_(c)^(+)→nπ^(+)π^(0),Λ_(c)^(+)→nπ^(+)π^(-)π^(+),and the Cabibbo-favored decayΛ_(c)^(+)→nK^(-)π^(+)π^(+)with statistical significances of 7.9σ,7.8σ,and>10σ,respectively.The branching fractions of these decays are measured to be B(Λ_(c)^(+)→nπ^(+)π^(0))=(0.64±0.09±0.02)%,B(Λ_(c)^(+)→nπ^(+)π^(-)π^(+))=(0.45±0.07±0.03)%,and B(Λ_(c)^(+)→nK^(-)π^(+)π^(+))=(1.90±0.08±0.09)%,where the first uncertainties are statistical and the second are systematic.We find that the branching fraction of the decayΛ_(c)^(+)→nπ^(+)π^(0)is about one order of magnitude higher than that ofΛ_(c)^(+)→nπ^(+).
基金Supported in part by National Key R&D Program of China(Grant Nos.2020YFA0406400,2020YFA0406300)National Natural Science Foundation of China(NSFC)(Grant Nos.11635010,11735014,11805086,11835012,11935015,11935016,11935018,11961141012,12022510,12025502,12035009,12035013,12192260,12192261,12192262,12192263,12192264,12192265)+18 种基金the Chinese Academy of Sciences(CAS)Large-Scale Scientific Facility ProgramJoint Large-Scale Scientific Facility Funds of the NSFC and CAS(Grant No.U1832207)the CAS Center for Excellence in Particle Physics(CCEPP)100 Talents Program of CASFundamental Research Funds for the Central Universities,Lanzhou University,University of Chinese Academy of SciencesThe Institute of Nuclear and Particle Physics(INPAC)and Shanghai Key Laboratory for Particle Physics and CosmologyERC(Grant No.758462)European Union's Horizon 2020 research and innovation programme under Marie Sklodowska-Curie grant agreement(Grant No.894790)German Research Foundation DFG(Grant No.443159800),Collaborative Research Center CRC 1044,GRK 2149Istituto Nazionale di Fisica Nucleare,ItalyMinistry of Development of Turkey(Grant No.DPT2006K-120470)National Science and Technology fundNational Science Research and Innovation Fund(NSRF)via the Program Management Unit for Human Resources&Institutional Development,Research and Innovation(Grant No.B16F640076)Olle Engkvist Foundation(Grant No.200-0605)STFC(United Kingdom)Suranaree University of Technology(SUT),Thailand Science Research and Innovation(TSRI),and National Science Research and Innovation Fund(NSRF)(Grant No.160355)The Royal Society,UK(Grant Nos.DH140054,DH160214)The Swedish Research CouncilU.S.Department of Energy(Grant No.DE-FG02-05ER41374)。
文摘We report a search for a heavier partner of the recently observed Z_(cs)(3985)^(-) state,denoted as Z_(cs)^('-),in the process e^(+)e^(−)→K^(+)D_(s)^(∗−) D^(∗0 )+ c.c.,based on e^(*)e^(-)collision data collected at the center-of-mass energies of √s=4.661,4.682 and 4.699 GeV with the BESIII detector.The Z_(cs)^('-) is of interest as it is expected to be a candidate for a hidden-charm and open-strange tetraquark.A partial-reconstruction technique is used to isolate K^(+)recoil-mass spectra,which are probed for a potential contribution from Z_(cs)^('-)→D_(s)^(∗−) D^(∗0 )+ c.c.We find an excess of Z_(cs)^('-)→D_(s)^(*-)-D^(*0)(c.c.)candidates with a significance of 2.1o,after considering systematic uncertainties,at a mass of(4123.5±0.7_(sat)±4.7_(syst.))MeV/c^(2).As the data set is limited in size,the upper limits are evaluated at the 90%confidence level on the product of the Born cross sections(σ^(Borm))and the branching fraction(B)of Z_(cs)^('-)→D_(s)^(*-)-D^(*0),under different assumptions of the Z_(cs)^('-) mass from 4.120 to 4.140 MeV and of the width from 10 to 50 MeV at the three center-of-mass energies.The upper limits of σ^(Born).B are found to be at the level of O(1)pb at each energy.Larger data samples are needed to confirm the Z_(cs)^('-) state and clarify its nature in the coming years.
基金supported by Tulane Weatherhead Endowment Fund (USA)
文摘Extracellular vesicles(EVs)are secreted by both eukaryotes and prokaryotes,and are present in all biological fluids of vertebrates,where they transfer DNA,RNA,proteins,lipids,and metabolites from donor to recipient cells in cell-to-cell communication.Some EV components can also indicate the type and biological status of their parent cells and serve as diagnostic targets for liquid biopsy.EVs can also natively carry or be modified to contain therapeutic agents(e.g.,nucleic acids,proteins,polysaccharides,and small molecules)by physical,chemical,or bioengineering strategies.Due to their excellent biocompatibility and stability,EVs are ideal nanocarriers for bioactive ingredients to induce signal transduction,immunoregulation,or other therapeutic effects,which can be targeted to specific cell types.Herein,we review EV classification,intercellular communication,isolation,and characterization strategies as they apply to EV therapeutics.This review focuses on recent advances in EV applications as therapeutic carriers from in vitro research towards in vivo animal models and early clinical applications,using representative examples in the fields of cancer chemotherapeutic drug,cancer vaccine,infectious disease vaccines,regenerative medicine and gene therapy.Finally,we discuss current challenges for EV therapeutics and their future development.
基金supported by the following funding sources:Science Committee of the Republic of Armenia Grant No.18T-1C180Australian Research Council and research grant Nos.DP180102629,DP170102389,DP170102204,DP150103061,FT130100303,and FT130100018+22 种基金Austrian Federal Ministry of Education,Science and Research,and Austrian Science Fund No.P 31361-N36Natural Sciences and Engineering Research Council of Canada,Compute Canada and CANARIEChinese Academy of Sciences and research grant No.QYZDJ-SSW-SLH011National Natural Science Foundation of China and research grant Nos.11521505,11575017,11675166,11761141009,11705209,and 11975076LiaoNing Revitalization Talents Program under contract No.XLYC1807135Shanghai Municipal Science and Technology Committee under contract No.19ZR1403000Shanghai Pujiang Program under Grant No.18PJ1401000the CAS Center for Excellence in Particle Physics(CCEPP)the Ministry of Education,Youth and Sports of the Czech Republic under Contract No.LTT17020Charles University grants SVV260448 and GAUK 404316European Research Council,7th Framework PIEF-GA-2013-622527Horizon 2020 Marie Sklodowska-Curie grant agreement No.700525’NIOBE,’Horizon 2020 Marie Sklodowska-Curie RISE project JENNIFER grant agreement No.644294Horizon 2020 ERC-Advanced Grant No.267104NewAve No.638528(European grants)L’Institut National de Physique Nucléaire et de Physique des Particules(IN2P3)du CNRS(France),BMBF,DFG,HGF,MPG and AvH Foundation(Germany)Department of Atomic Energy and Department of Science and Technology(India)Israel Science Foundation grant No.2476/17United States-Israel Binational Science Foundation grant No.2016113Istituto Nazionale di Fisica Nucleare and the research grants BELLE2Japan Society for the Promotion of Science,Grant-in-Aid for Scientific Research grant Nos.16H03968,16H03993,16H06492,16K05323,17H01133,17H05405,18K03621,18H03710,18H05226,19H00682,26220706,and 26400255the National Institute of Informatics,and Science Information NETwork 5(SINET5)the Ministry of Education,Culture,Sports,Science,an
文摘From April to July 2018,a data sample at the peak energy of the T(4 S) resonance was collected with the Belle Ⅱ detector at the SuperKEKB electron-positron collider.This is the first data sample of the Belle Ⅱ experiment.Using Bhabha and digamma events,we measure the integrated luminosity of the data sample to be(496.3±0.3±3.0) pb-1,where the first uncertainty is statistical and the second is systematic.This work provides a basis for future luminosity measurements at Belle Ⅱ.
文摘High transverse momentum(pT)particle production is suppressed owing to the parton(jet)energy loss in the hot dense medium created in relativistic heavy-ion collisions.Redistribution of energy at low-to-modest pT has been difficult to measure,owing to large anisotropic backgrounds.We report a data-driven method for background evaluation and subtraction,exploiting the away-side pseudorapidity gaps,to measure the jetlike correlation shape in Au+Au collisions at √sNN=200 GeV in the STAR experiment.The correlation shapes,for trigger particles pT>3GeV/c and various associated particle pT ranges within 0.5<pT<10GeV/c,are consistent with Gaussians,and their widths increase with centrality.The results indicate jet broadening in the medium created in central heavy-ion collisions.
基金supported by the National Natural Science Foundation of China (No.51041007)the Tribology Science Fund of State Key Laboratory of Tribology (No.SKLTKF10B07)
文摘The corrosion behavior of type 1045（AISI） carbon steel（CS） in oil-water fluids was investigated by considering the surface wetting state as the breakthrough point.The surface water wetting percentage（SWWP）and corrosion weight loss of CS in different oil-water fluids were measured.The morphology and composition of the corrosion films were detected via scanning electron microscopy,electron-probe facescanning technology and Fourier-transform infrared spectroscopy.The results indicated that the corrosion weight loss of CS in the oil-water fluids corresponded with SWWP and that the corrosion process was influenced by the participation of oil.
基金Supported in part by National Key R&D Program of China(2020YFA0406300, 2020YFA0406400)National Natural Science Foundation of China(NSFC)(11625523, 11635010, 11735014, 11822506, 11835012, 11935015, 11935016, 11935018, 11961141012, 12022510, 12025502, 12035009, 12035013,12061131003,12075252)+16 种基金the Chinese Academy of Sciences(CAS)Large-Scale Scientific Facility ProgramJoint Large-Scale Scientific Facility Funds of the NSFC and CAS(U1732263, U1832207)CAS Key Research Program of Frontier Sciences(QYZDJ-SSW-SLH040)100 Talents Program of CASINPAC and Shanghai Key Laboratory for Particle Physics and CosmologyERC(758462)European Union Horizon 2020 research and innovation programme Marie Sklodowska-Curie grant agreement(894790)German Research Foundation DFG(443159800), Collaborative Research Center CRC 1044, FOR 2359, GRK 214Istituto Nazionale di Fisica Nucleare, ItalyMinistry of Development of Turkey under Contract No. DPT2006K-120470National Science and Technology fundOlle Engkvist Foundation(200-0605)STFC(United Kingdom)The Knut and Alice Wallenberg Foundation(Sweden)(2016.0157)The Royal Society, UK(DH140054, DH160214)The Swedish Research CouncilU. S. Department of Energy(DE-FG02-05ER41374, DE-SC-0012069)
文摘Using inclusive decays of J/ψ aprecise determination of the number of J/ψ events collected with the BESIII detector was performed.For the two data sets taken in 2009 and 2012,the numbers of J/ψ events were recalculated to be(224.0±1.3)×10^(6) and(1088.5±4.4)×10^(6),respectively;these numbers are in good agreement with the previous measurements. For the J/ψ sample taken in 2017-2019,the number of events was determined to be(8774.0±39.4)×10^(6).The total number of J/ψ events collected with the BESIII detector was determined to be(10087±44)×10^(6),where the uncertainty is dominated by systematic effects,and the statistical uncertainty is negligible.
基金Supported in part by National Key R&D Program of China(2020YFA0406300,2020YFA0406400)National Natural Science Foundation of China(NSFC)under Contracts Nos.(11625523,11635010,11735014,11822506,11835012,11935015,11935016,11935018,11961141012,12022510,12025502,12035009,12035013,12061131003)+16 种基金the Chinese Academy of Sciences(CAS)Large-Scale Scientific Facility ProgramJoint Large-Scale Scientific Facility Funds of the NSFC and CAS under Contracts Nos.(U1732263,U1832207)CAS Key Research Program of Frontier Sciences under Contract No.(QYZDJ-SSW-SLH040)100 Talents Program of CASINPAC and Shanghai Key Laboratory for Particle Physics and CosmologyERC under Contract No.(758462)European Union Horizon 2020 research and innovation programme under Contract No.Marie Sklodowska-Curie grant agreement No(894790)German Research Foundation DFG under Contracts Nos.(443159800),Collaborative Research Center CRC 1044,FOR 2359,GRK 214Istituto Nazionale di Fisica Nucleare,ItalyMinistry of Development of Turkey under Contract No.(DPT2006K-120470)National Science and Technology fundOlle Engkvist Foundation under Contract No.(200-0605)STFC(United Kingdom)The Knut and Alice Wallenberg Foundation(Sweden)under Contract No.(2016.0157)The Royal Society,UK under Contracts Nos.(DH140054,DH160214)The Swedish Research CouncilU.S.Department of Energy under Contracts Nos.(DE-FG02-05ER41374,DE-SC-001206)。
文摘The cross sections of e^(+)e^(-)→K^(+)K^(-)J/Ψat center-of-mass energies from 4.127 to 4.600 GeV are measured based on 15.6 fb-1data collected with the BESⅢ detector operating at the BEPCⅡ storage ring.Two resonant structures are observed in the line shape of the cross sections.The mass and width of the first structure are measured to be(4225.3±2.3±21.5)MeV and(72.9±6.1±30.8)MeV,respectively.They are consistent with those of the established Y(4230).The second structure is observed for the first time with a statistical significance greater than 8σ,denoted as Y(4500).Its mass and width are determined to be(4484.7±13.3±24.1)MeV and(111.1±30.1±15.2)MeV,respectively.The first presented uncertainties are statistical and the second ones are systematic.The product of the electronic partial width with the decay branching fractionΓ(Y(4230)→e^(+)e^(−))B(Y(4230)→K^(+)K^(−)J/Ψ)is reported.
基金Supported in part by National Key R&D Program of China(2020YFA0406300,2020YFA0406400)National Natural Science Foundation of China(NSFC)(11625523,11635010,11735014,11822506,11835012,11935015,11935016,11935018,11961141012,12022510,12025502,12035009,12035013,12061131003)+16 种基金the Chinese Academy of Sciences(CAS)Large-Scale Scientific Facility ProgramJoint Large-Scale Scientific Facility Funds of the NSFC and CAS(U1732263,U1832207)CAS Key Research Program of Frontier Sciences(QYZDJ-SSW-SLH040)100 Talents Program of CASINPAC and Shanghai Key Laboratory for Particle Physics and CosmologyERC(758462)European Union Horizon 2020 research and innovation programme(Marie Sklodowska-Curie grant agreement No 894790)German Research Foundation DFG(443159800),Collaborative Research Center CRC 1044,GRK 2149Istituto Nazionale di Fisica Nucleare,ItalyMinistry of Development of Turkey(DPT2006K-120470)National Science and Technology fundOlle Engkvist Foundation(200-0605)STFC(United Kingdom)The Knut and Alice Wallenberg Foundation(Sweden)(2016.0157)The Royal Society,UK(DH140054,DH160214)The Swedish Research CouncilU.S.Department of Energy(DE-FG02-05ER41374,DE-SC-0012069)。
文摘The integrated luminosities of data samples collected in the BESⅢ experiment in 2016-2017 at centerof-mass energies between 4.19 and 4.28 GeV are measured with a precision better than 1% by analyzing large-angle Bhabha scattering events.The integrated luminosities of old datasets collected in 2010-2014 are updated by considering corrections related to detector performance,offsetting the effect of newly discovered readout errors in the electromagnetic calorimeter,which can haphazardly occur.
基金Supported in part by National Key R&D Program of China(2020YFA0406400,2020YFA0406300)National Natural Science Foundation of China(NSFC)(11635010,11735014,11805086,11835012,11935015,11935016,11935018,11961141012,12022510,12025502,12035009,12035013,12192260,12192261,12192262,12192263,12192264,12192265)+17 种基金the Chinese Academy of Sciences(CAS)Large-Scale Scientific Facility ProgramJoint Large-Scale Scientific Facility Funds of the NSFC and CAS(U1832207)CAS Key Research Program of Frontier Sciences(QYZDJ-SSW-SLH040)100 Talents Program of CASFundamental Research Funds for the Central Universities,Lanzhou University,University of Chinese Academy of SciencesThe Institute of Nuclear and Particle Physics(INPAC)and Shanghai Key Laboratory for Particle Physics and CosmologyERC(758462)European Union's Horizon 2020 research and innovation programme under Marie Sklodowska-Curie grant agreement(894790)German Research Foundation DFG(443159800),Collaborative Research Center CRC 1044,GRK 2149Istituto Nazionale di Fisica Nucleare,ItalyMinistry of Development of Turkey(DPT2006K-120470)National Science and Technology fundNational Science Research and Innovation Fund(NSRF)via the Program Management Unit for Human Resources&Institutional Development,Research and Innovation(B16F640076)STFC(United Kingdom)Suranaree University of Technology(SUT),Thailand Science Research and Innovation(TSRI),and National Science Research and Innovation Fund(NSRF)(160355)The Royal Society,UK(DH140054,DH160214)The Swedish Research CouncilU.S.Department of Energy(DE-FG02-05ER41374)。
文摘From December 2019 to June 2021,the BESⅢ experiment collected approximately 5.85 fb^(−1) of data at center-of-mass energies between 4.61 and 4.95 GeV.This is the highest collision energy BEPCⅡ has reached to date.The accumulated e^(+)e^(−) annihilation data samples are useful for studying charmonium(-like)states and charmed-hadron decays.By adopting a novel method of analyzing the production of A_(c)^(+)A_(c)^(-) pairs in e^(+)e^(−) annihilation,the center-of-mass energies are measured with a precision of 0.6 MeV.Integrated luminosities are measured with a precision of better than 1% by analyzing the events of large-angle Bhabha scattering.These measurements provide important inputs to analyses based on these data samples.
基金Supported in part by National Key Research and Development Program of China(2020YFA0406300,2020YFA0406400)National Natural Science Foundation of China(NSFC)(11625523,11635010,11735014,11822506,11835012,11935015,11935016,11935018,11961141012)+12 种基金the Chinese Academy of Sciences(CAS)Large-Scale Scientific Facility ProgramJoint Large-Scale Scientific Facility Funds of the NSFC and CAS(U1732263,U1832207)CAS Key Research Program of Frontier Sciences(QYZDJ-SSW-SLH003,QYZDJ-SSW-SLH040)100 Talents Program of CAS,INPAC and Shanghai Key Laboratory for Particle Physics and Cosmology,ERC(758462)European Union Horizon 2020 research and innovation programme(Marie Sklodowska-Curie grant agreement No 894790)German Research Foundation DFG(443159800)Collaborative Research Center CRC 1044,FOR 2359,FOR 2359,GRK 214Istituto Nazionale di Fisica Nucleare,Italy,Ministry of Development of Turkey(DPT2006K-120470)National Science and Technology fund,Olle Engkvist Foundation(200-0605)STFC(United Kingdom)The Knut and Alice Wallenberg Foundation(Sweden)(2016.0157)The Royal Society,UK(DH140054,DH160214)The Swedish Research Council,U.S.Department of Energy(DE-FG02-05ER41374,DE-SC-0012069)。
文摘During the 2016-17 and 2018-19 running periods,the BESIII experiment collected 7.5 fb of e^(+)e^(-)collision data at center-of-mass energies ranging from 4.13 to 4.44 GeV.These data samples are primarily used for the study of excited charmonium and charmoniumlike states.By analyzing the di-muon process e^(+)e^(-)→(γISR=FSR)μ^(+)μ^(-),we measure the center-of-mass energies of the data samples with a precision of 0.6 MeV.Through a run-by-run study,we find that the center-of-mass energies were stable throughout most of the data-collection period.
基金Supported in part by National Key Basic Research Program of China(2015CB856700)National Natural Science Foundation of China(NSFC)(11235011,11275266,11335008,11425524,11625523,11635010)+16 种基金the Chinese Academy of Sciences(CAS) Large-Scale Scientific Facility Programthe CAS Center for Excellence in Particle Physics(CCEPP)Joint Large-Scale Scientific Facility Funds of the NSFC and CAS(U1332201,U1532257,U1532258)CAS(KJCX2-YW-N29,KJCX2-YW-N45,QYZDJ-SSW-SLH003)100 Talents Program of CASNational 1000 Talents Program of ChinaINPAC and Shanghai Key Laboratory for Particle Physics and CosmologyGerman Research Foundation DFG(Collaborative Research Center CRC 1044,FOR 2359)Istituto Nazionale di Fisica Nucleare,ItalyKoninklijke Nederlandse Akademie van Wetenschappen(KNAW)(530-4CDP03)Ministry of Development of Turkey(DPT2006K-120470)National Science and Technology fundThe Swedish Research CouncilU.S. Department of Energy under(DE-FG02-05ER41374,DE-SC-0010118,DE-SC-0010504,DE-SC-0012069)University of Groningen(RuG)the Helmholtzzentrum fuer Schwerionenforschung GmbH(GSI),DarmstadtWCU Program of National Research Foundation of Korea(R32-2008-000-10155-0)
文摘We study the hadronic decays of ∧c+ to the final states ∑+η and ∑+η’,using an e+e-annihilation data sample of 567 pb-1 taken at a center-of-mass energy of 4.6 GeV with the BESIII detector at the BEPCⅡ collider.We find evidence for the decays ∧c+→∑+η and ∑+η’ with statistical significance of 2.5σ and 3.2σ,respectively.Normalizing to the reference decays ∧c+→∑+π0 and ∑+ω,we obtain the ratios of the branching fractions■and ■to be 0.35±0.16±0.02 and 0.86±0.34±0.04,respectively.The upper limits at the 90% confidence level are set to be■and■.Using BESIII measurements of the branching fractions of the reference decays,we determine B（∧c+→∑+η）=（0.41±0.19±0.05）%（<0.68%）and B（∧c+→∑+η’）=（1.34±0.53 ±0.19）%（<1.9%）.Here,the first uncertainties are statistical and the second systematic.The obtained branching fraction of ∧c+→∑+η is consistent with the previous measurement,and the branching fraction of ∧c+→∑+η’ is measured for the first time.
基金Supported in part by National Key Basic Research Program of China(2015CB856700)National Natural Science Foundation of China(NSFC)(11335008,11425524,11625523,11635010,11735014)+9 种基金the Chinese Academy of Sciences(CAS)Large-Scale Scientific Facility Program,the CAS Center for Excellence in Particle Physics(CCEPP)Joint Large-Scale Scientific Facility Funds of the NSFC and CAS(U1532257,U1532258,U1732263)CAS Key Research Program of Frontier Sciences(QYZDJ-SSW-SLH003,QYZDJ-SSW-SLH040)100 Talents Program of CASINPAC,Shanghai Key Laboratory for Particle Physics and Cosmology,German Research Foundation DFG under Contracts Nos.Collaborative Research Center CRC 1044,FOR 2359Istituto Nazionale di Fisica Nucleare,Italy,Koninklijke Nederlandse Akademie van Wetenschappen(KNAW)(530-4CDP03)Ministry of Development of Turkey(DPT2006K-120470)National Science and Technology fund,The Swedish Research CouncilU.S.Department of Energy(DE-FG02-05ER41374,DE-SC-0010118,DE-SC-0010504,DE-SC-0012069),University of Groningen(RuG)the Helmholtzzentrum fuer Schwerionenforschung GmbH(GSI),Darmstadt
文摘Studies of e^+e~→D_s^+■^((*)0)K^-and the P-wave charmed-strange mesons are performed based on an e^+e^-collision data sample corresponding to an integrated luminosity of 567 pb^(-1) collected with the BESIII detector at s^(1/2)=4.600 GeV. The processes of e^+e^-→D_s^+■^(*0)K^- and D_s^+■~0K^- are observed for the first time and are found to be dominated by the modes D_s^+D_(s1)(2536)^-and D_s^+D_(s2)~*(2573)^-, respectively. The Born cross sections are measured to be σ~B(e^+e^-→D_s^+■^(*0)K^-) =(10.1±2.3±0.8) pb and σ~B(e^+e^-→D_s^+■~0K^-) =(19.4±2.3± 1.6) pb, and the products of Born cross section and the decay branching fraction are measured to be σ~B(e^+e^-→D_s^+D_(s1)(2536)^-+c.c.)·B(D_(s1)(2536)^-→■^(*0)K^-)=(7.5±1.8±0.7) pb and σ~B(e^+e^-→D_s^+D_(s2)~*(2573)^-+ c.c.)·B(D_(s2)~*(2573)^-→■~0 K^-)=(19.7 ± 2.9 ±2.0) pb. For the D_(s1)(2536)^-and D_(s2)~*(2573)^-mesons, the masses and widths are measured to be M(D_(s1)(2536)^-)=(2537.7±0.5 ±3.1) MeV/c2, Γ(D_(s1)(2536)^-) =(1.7 ±1.2 ±0.6)MeV, and M(D_(s2)~*(2573)^-)=(2570.7±2.0 ±1.7) MeV/c^2, Γ(D_(s2)~*(2573)^-)=(17.2 ±3.6 ±1.1) MeV. The spin-parity of the D_(s2)~*(2573)^-meson is determined to be J^p= 2^+. In addition, the processes e^+e^-→D_s^+■^((*)0)K^-are searched for using the data samples taken at four(two) center-of-mass energies between 4.416(4.527) and 4.575 GeV, and upper limits at the 90% confidence level on the cross sections are determined.
文摘Inspired by the successful application of Cas9 gene editing for“genome surgery,”we are looking back at what has been accomplished in the ten years of CRISPR editing.Intense effort is now focused on how to utilize the unique functions of CRISPR-Cas systems for molecular diagnostics and the next generation of therapeutic tools.CRISPR-Cas systems have two major advantages for gene editing that render them attractive for these new applications,specifically the ability to easily control their target recognition specificity and to couple this specificity to a targeted or secondary cleavage activity.However,despite the great potential of CRISPR/Cas for both gene editing and diagnosis,its medical applications have yet to be fully realized due factors that limit their delivery or utility for point-of-care(POC)applications.In this editorial note,we discuss how nanotechnology can address challenges associated with new CRISPR applications and what nanotechnology-specific advances are needed to circumvent remaining barriers that limit the development or use of new CRISPR/CAS-based genome editing and diagnostic approaches.
