目的:研究苏州市吴江区40岁以上人群骨密度(bone mineral density,BMD)与血清钙(Ca)磷(P)代谢、维生素D及骨代谢间相关性。方法:采用多阶段分层随机抽样方法,选取2018年3—7月吴江区社区40岁以上人群骨质疏松症调查数据。采取双能X线吸...目的:研究苏州市吴江区40岁以上人群骨密度(bone mineral density,BMD)与血清钙(Ca)磷(P)代谢、维生素D及骨代谢间相关性。方法:采用多阶段分层随机抽样方法,选取2018年3—7月吴江区社区40岁以上人群骨质疏松症调查数据。采取双能X线吸收法(DXA)骨密度仪进行腰椎正位(L_(1-4)和L_(2-4))和股骨近端(股骨颈、大转子和全髋骨)BMD的测定。结果:本调查对象217例中男82例,女135例;平均年龄(57.03±10.43)岁。各部位BMD水平男女间差异均具有统计学意义(P<0.01)。单因素分析显示,性别、年龄、体质量指数(BMI)、P、碱性磷酸酶(ALP)、β-胶原降解产物(β-CTX)、总Ⅰ型胶原氨基端前肽(PINP)在各部位BMD差异均有统计学意义(P<0.01),25羟基维生素D[25(OH)D 3]仅在大转子BMD、全髋BMD差异有统计学意义(P<0.05)。在控制性别、年龄、BMI后,Ca、25(OH)D 3在各部位BMD差异均无统计学意义,而血清P与L_(1-4)、L_(2-4)BMD仅在0.05水平上相关,差异具有统计学意义。多元逐步回归分析结果显示,高龄、女性是BMD的危险因素,BMI与各部位BMD呈正相关(均β>0,P<0.05),P与股骨颈(β=-0.158)、大转子(β=-0.158)、全髋(β=-0.158)BMD呈负相关(P<0.05)。结论:吴江区40岁以上人群BMD与相关血生化、骨代谢指标具有显著相关性,血清P与股骨颈、大转子、全髋BMD呈负相关,PINP与各部位BMD值均呈负相关。展开更多
Remote-sensing images of Mars contain rich information about its surface morphology,topography,and geological structure.These data are fundamental for scientific research and exploration.Prior to China’s first Mars e...Remote-sensing images of Mars contain rich information about its surface morphology,topography,and geological structure.These data are fundamental for scientific research and exploration.Prior to China’s first Mars exploration mission,data from six advanced optical imaging systems of different missions in the Martian orbit had been used to generate Mars global/near-global image datasets with spatial resolutions of better than 1 km:the visual imaging system of Mariner 9,visual imaging subsystem cameras of Viking 1 and 2,Mars Orbiter Camera-Wide Angle(MOC-WA)of the Mars Global Surveyor(MGS),Context Camera(CTX)of the Mars Reconnaissance Orbiter(MRO),High Resolution Stereo Camera(HRSC)of Mars Express(MEX),and Thermal Emission Imaging System(THEMIS)of the Mars Odyssey Orbiter[1,2].展开更多
文摘目的:研究苏州市吴江区40岁以上人群骨密度(bone mineral density,BMD)与血清钙(Ca)磷(P)代谢、维生素D及骨代谢间相关性。方法:采用多阶段分层随机抽样方法,选取2018年3—7月吴江区社区40岁以上人群骨质疏松症调查数据。采取双能X线吸收法(DXA)骨密度仪进行腰椎正位(L_(1-4)和L_(2-4))和股骨近端(股骨颈、大转子和全髋骨)BMD的测定。结果:本调查对象217例中男82例,女135例;平均年龄(57.03±10.43)岁。各部位BMD水平男女间差异均具有统计学意义(P<0.01)。单因素分析显示,性别、年龄、体质量指数(BMI)、P、碱性磷酸酶(ALP)、β-胶原降解产物(β-CTX)、总Ⅰ型胶原氨基端前肽(PINP)在各部位BMD差异均有统计学意义(P<0.01),25羟基维生素D[25(OH)D 3]仅在大转子BMD、全髋BMD差异有统计学意义(P<0.05)。在控制性别、年龄、BMI后,Ca、25(OH)D 3在各部位BMD差异均无统计学意义,而血清P与L_(1-4)、L_(2-4)BMD仅在0.05水平上相关,差异具有统计学意义。多元逐步回归分析结果显示,高龄、女性是BMD的危险因素,BMI与各部位BMD呈正相关(均β>0,P<0.05),P与股骨颈(β=-0.158)、大转子(β=-0.158)、全髋(β=-0.158)BMD呈负相关(P<0.05)。结论:吴江区40岁以上人群BMD与相关血生化、骨代谢指标具有显著相关性,血清P与股骨颈、大转子、全髋BMD呈负相关,PINP与各部位BMD值均呈负相关。
基金supported by the China National Space Administration(CNSA)the National Key R&D Program of China(2022YFF0503204)+1 种基金the Key Research Program of the Chinese Academy of Sciences(ZDBS-SSW-TLC001)the National Natural Science Foundation of China(12203073,42371384)。
文摘Remote-sensing images of Mars contain rich information about its surface morphology,topography,and geological structure.These data are fundamental for scientific research and exploration.Prior to China’s first Mars exploration mission,data from six advanced optical imaging systems of different missions in the Martian orbit had been used to generate Mars global/near-global image datasets with spatial resolutions of better than 1 km:the visual imaging system of Mariner 9,visual imaging subsystem cameras of Viking 1 and 2,Mars Orbiter Camera-Wide Angle(MOC-WA)of the Mars Global Surveyor(MGS),Context Camera(CTX)of the Mars Reconnaissance Orbiter(MRO),High Resolution Stereo Camera(HRSC)of Mars Express(MEX),and Thermal Emission Imaging System(THEMIS)of the Mars Odyssey Orbiter[1,2].