Objective:As a popular complementary therapy,the safety of acupuncture must be considered.Acupuncture case reports of adverse events(ACR-AEs)significantly contribute to the assessment of acupuncture safety.However,the...Objective:As a popular complementary therapy,the safety of acupuncture must be considered.Acupuncture case reports of adverse events(ACR-AEs)significantly contribute to the assessment of acupuncture safety.However,the reporting quality of ACR-AEs remains unclear.We aimed to promote the application of the CARE(case report)guidelines and improve the reporting quality of ACR-AEs.Methods:We systematically searched for ACR-AE from six databases:Medline,Embase,Chinese Biomedical Literature Service System,China National Knowledge Infrastructure,Wanfang Data,and VIP,and collected published ACR-AEs from January 1,2016,to December 31,2020.We included only case reports of adverse events related to acupuncture therapy.The retrieved case reports were screened and filtered by two reviewers independently.Then,basic information extraction and CARE evaluation of the included ACR-AEs wereperformed.Results:A total of 56 ACR-AE were included,15 of which were from China.The top two major diseases were nervous system diseases(28.6%)and infections(21.4%).For all ACR-AEs,seven of 30 CARE subordinate items were reported in 30%or less,seven items were reported in 30-60%,and only five items got reporting proportion over 90%.In Chinese ACR-AE,only three items,"the main concerns and symptoms of the patient(5b)","types of intervention(9a)"and"adverse and unanticipated events(1od)"were sufficiently reported.In English ACR-AE,item"the main concerns and symptoms of the patient(5b)"and item"the primary takeaway lessons(11d)"were also generally reported.Conclusion:Overall,the reporting quality of ACR-AE was unsatisfactory,and we believe that a special reporting guideline for clinical cases targeted at acupuncture should be extended in future studies.展开更多
通过天然生物质壳聚糖与有机硅制备壳聚糖负载氧化硅叶面喷施材料(NCSI),并将其应用于灌浆期临稻16、南粳2728、郑旱10号和农垦58,以探究其对水稻吸收砷(As)的影响.结果表明,在100μmol·L^(-1)五价砷[As(Ⅴ)]水培环境下,叶面喷施30...通过天然生物质壳聚糖与有机硅制备壳聚糖负载氧化硅叶面喷施材料(NCSI),并将其应用于灌浆期临稻16、南粳2728、郑旱10号和农垦58,以探究其对水稻吸收砷(As)的影响.结果表明,在100μmol·L^(-1)五价砷[As(Ⅴ)]水培环境下,叶面喷施30 mL NCSI促进叶片As的累积,降低了根和籽粒As的累积.其中,叶面喷施NCSI后3 d,南粳2728、郑旱10号和农垦58籽粒As含量较空白组分别降低14.44%、21.66%和10.85%.同时,叶面喷施处理NCSI,提高了水稻叶片CAT和SOD酶的活性,并提高了GSH质量摩尔浓度,表明NCSI的喷施缓解As对水稻的胁迫,提高水稻对As耐受性,降低As对水稻的毒害作用.叶面喷施NCSI降低水稻籽粒As积累的主要作用机制可能是NCSI诱导叶片GSH生成,使更多的As(Ⅴ)还原为三价砷[As(Ⅲ)],从而促进As在叶片螯合,抑制As向籽粒迁移.因此,叶面喷施NCSI可作为一种叶面调控技术解决水稻As超标问题,为我国大米安全生产提供科学依据.展开更多
基金Supported by Special Project of "Lingnan Modernization of Traditional Chinese Medicine" in 2019,Guangdong Provincial R&D Program:2020B1111100008Young Science and Technology Talents Fund of The Affiliated TCM Hospital of Guangzhou Medical University:2022RC07
文摘Objective:As a popular complementary therapy,the safety of acupuncture must be considered.Acupuncture case reports of adverse events(ACR-AEs)significantly contribute to the assessment of acupuncture safety.However,the reporting quality of ACR-AEs remains unclear.We aimed to promote the application of the CARE(case report)guidelines and improve the reporting quality of ACR-AEs.Methods:We systematically searched for ACR-AE from six databases:Medline,Embase,Chinese Biomedical Literature Service System,China National Knowledge Infrastructure,Wanfang Data,and VIP,and collected published ACR-AEs from January 1,2016,to December 31,2020.We included only case reports of adverse events related to acupuncture therapy.The retrieved case reports were screened and filtered by two reviewers independently.Then,basic information extraction and CARE evaluation of the included ACR-AEs wereperformed.Results:A total of 56 ACR-AE were included,15 of which were from China.The top two major diseases were nervous system diseases(28.6%)and infections(21.4%).For all ACR-AEs,seven of 30 CARE subordinate items were reported in 30%or less,seven items were reported in 30-60%,and only five items got reporting proportion over 90%.In Chinese ACR-AE,only three items,"the main concerns and symptoms of the patient(5b)","types of intervention(9a)"and"adverse and unanticipated events(1od)"were sufficiently reported.In English ACR-AE,item"the main concerns and symptoms of the patient(5b)"and item"the primary takeaway lessons(11d)"were also generally reported.Conclusion:Overall,the reporting quality of ACR-AE was unsatisfactory,and we believe that a special reporting guideline for clinical cases targeted at acupuncture should be extended in future studies.
文摘通过天然生物质壳聚糖与有机硅制备壳聚糖负载氧化硅叶面喷施材料(NCSI),并将其应用于灌浆期临稻16、南粳2728、郑旱10号和农垦58,以探究其对水稻吸收砷(As)的影响.结果表明,在100μmol·L^(-1)五价砷[As(Ⅴ)]水培环境下,叶面喷施30 mL NCSI促进叶片As的累积,降低了根和籽粒As的累积.其中,叶面喷施NCSI后3 d,南粳2728、郑旱10号和农垦58籽粒As含量较空白组分别降低14.44%、21.66%和10.85%.同时,叶面喷施处理NCSI,提高了水稻叶片CAT和SOD酶的活性,并提高了GSH质量摩尔浓度,表明NCSI的喷施缓解As对水稻的胁迫,提高水稻对As耐受性,降低As对水稻的毒害作用.叶面喷施NCSI降低水稻籽粒As积累的主要作用机制可能是NCSI诱导叶片GSH生成,使更多的As(Ⅴ)还原为三价砷[As(Ⅲ)],从而促进As在叶片螯合,抑制As向籽粒迁移.因此,叶面喷施NCSI可作为一种叶面调控技术解决水稻As超标问题,为我国大米安全生产提供科学依据.
