Objective:The objective of this study is to systematically review and analyze the efficacy of acupuncture for pain caused by primary liver cancer(PLC).Materials and Methods:We searched databases,including PubMed,Medli...Objective:The objective of this study is to systematically review and analyze the efficacy of acupuncture for pain caused by primary liver cancer(PLC).Materials and Methods:We searched databases,including PubMed,Medline,Embase,Cochrane Library,Web of Science,China National Knowledge Infrastructure,Chinese Science and Technology Periodicals Database(VIP),Wanfang,and SinoMed/Chinese Biomedical Database(CBM),and retrieved randomized controlled trials(RCTs)that used acupuncture as the primary intervention to treat pain caused by PLC.Two investigators then screened the articles,extracted and pooled data,and evaluated the risk of bias of the included articles according to the Cochrane Handbook.RevMan5.3 was used for the meta-analysis of eligible RCTs.Results:A total of 145 articles were retrieved;after screening,8 RCTs involving 496 patients were eventually included in this meta-analysis.The results showed that acupuncture effectively improved cancer pain and was superior to Western medicine.Moreover,acupuncture was fast-acting for pain relief,prolonged the relief,and prevented relapse.Its adverse reaction rate was also significantly lower than that of Western medicine.No significant difference was observed in Visual Analog Scale score between acupuncture and Western medicine.Conclusion:Acupuncture relieves pain caused by liver cancer and can be used as an adjunct and alternative therapy for drug treatment.The existing research evidence is not yet objective or comprehensive,and more rigorous clinical trials are needed to validate the results.展开更多
Interactions between chalcopyrite and bornite during bioleaching by moderately thermophilic bacteria were investigated mainly by X-ray diffraction, scanning electron microscopy, and electrochemical measurements perfor...Interactions between chalcopyrite and bornite during bioleaching by moderately thermophilic bacteria were investigated mainly by X-ray diffraction, scanning electron microscopy, and electrochemical measurements performed in conjunction with bioleaching experiments. The results showed that a synergistic effect existed between chalcopyrite and bornite during bioleaching by both Acidithiobacillus caldus and Leptospirillum ferriphilum and that extremely high copper extraction could be achieved when chalcopyrite and bornite coexisted in a bioleaching system. Bornite dissolved preferentially because of its lower corrosion potential, and its dissolution was accelerated by the galvanic current during the initial stage of bioleaching. The galvanic current and optimum redox potential of 390-480 m V vs. Ag/Ag Cl promoted the reduction of chalcopyrite to chalcocite(Cu2S), thus accelerating its dissolution.展开更多
基金supported by Key Project of Chinese National Programs for Fundamental Research and Development(973 Program)(No.2009CB522900,No.2015CB554501)the Project of Three-Year Action Plan for development of traditional Chinese medicine in Shanghai(No.ZY(2018-2020)-CCCX-2004-01)Shanghai Clinical Research Center for Acupuncture and Moxibustion(No.20MC1920500)。
文摘Objective:The objective of this study is to systematically review and analyze the efficacy of acupuncture for pain caused by primary liver cancer(PLC).Materials and Methods:We searched databases,including PubMed,Medline,Embase,Cochrane Library,Web of Science,China National Knowledge Infrastructure,Chinese Science and Technology Periodicals Database(VIP),Wanfang,and SinoMed/Chinese Biomedical Database(CBM),and retrieved randomized controlled trials(RCTs)that used acupuncture as the primary intervention to treat pain caused by PLC.Two investigators then screened the articles,extracted and pooled data,and evaluated the risk of bias of the included articles according to the Cochrane Handbook.RevMan5.3 was used for the meta-analysis of eligible RCTs.Results:A total of 145 articles were retrieved;after screening,8 RCTs involving 496 patients were eventually included in this meta-analysis.The results showed that acupuncture effectively improved cancer pain and was superior to Western medicine.Moreover,acupuncture was fast-acting for pain relief,prolonged the relief,and prevented relapse.Its adverse reaction rate was also significantly lower than that of Western medicine.No significant difference was observed in Visual Analog Scale score between acupuncture and Western medicine.Conclusion:Acupuncture relieves pain caused by liver cancer and can be used as an adjunct and alternative therapy for drug treatment.The existing research evidence is not yet objective or comprehensive,and more rigorous clinical trials are needed to validate the results.
基金financially supported by the National Natural Science Foundation of China (Nos. 51374248 and 51320105006)the Program for New Century Excellent Talents in University (No. NCET-13-0595)the China Postdoctoral Science Foundation (No. 2014T70692)
文摘Interactions between chalcopyrite and bornite during bioleaching by moderately thermophilic bacteria were investigated mainly by X-ray diffraction, scanning electron microscopy, and electrochemical measurements performed in conjunction with bioleaching experiments. The results showed that a synergistic effect existed between chalcopyrite and bornite during bioleaching by both Acidithiobacillus caldus and Leptospirillum ferriphilum and that extremely high copper extraction could be achieved when chalcopyrite and bornite coexisted in a bioleaching system. Bornite dissolved preferentially because of its lower corrosion potential, and its dissolution was accelerated by the galvanic current during the initial stage of bioleaching. The galvanic current and optimum redox potential of 390-480 m V vs. Ag/Ag Cl promoted the reduction of chalcopyrite to chalcocite(Cu2S), thus accelerating its dissolution.