To the Editor:Glaucoma is the primary cause of irreversible blindness. Surgery is the main treatment option if intraocular pressure (IOP) cannot be controlled with medications. Local fibroblast proliferation and colla...To the Editor:Glaucoma is the primary cause of irreversible blindness. Surgery is the main treatment option if intraocular pressure (IOP) cannot be controlled with medications. Local fibroblast proliferation and collagen deposition cause stenosis of drainage channels and scar formation in the filtration area, which are the main causes of unsuccessful antiglaucoma surgery. Application of mitomycin C during surgery is one of the most widely performed clinical interventions aimed at modifying the wound healing process. However, recent reports suggest that there is scope to further improve the outcomes of mitomycin C application in surgery.展开更多
While the common practice of decomposing general quantum algorithms into a collection of single-and two-qubit gates is conceptually simple,in many cases it is possible to have more efficient solutions where quantum ga...While the common practice of decomposing general quantum algorithms into a collection of single-and two-qubit gates is conceptually simple,in many cases it is possible to have more efficient solutions where quantum gates engaging multiple qubits are used.In the noisy intermediate-scale quantum(NISQ)era where a universal error correction is still unavailable,this strategy is particularly appealing since it can significantly reduce the computational resources required for executing quantum algorithms.In this work,we experimentally investigate a three-qubit ControlledCPHASE-SWAP(CCZS)gate on superconducting quantum circuits.By exploiting the higher energy levels of superconducting qubits,we are able to realize a Fredkin-like CCZS gate with a duration of 40 ns,which is comparable to typical single-and two-qubit gates realized on the same platform.By performing quantum process tomography for the two target qubits,we obtain a process fidelity of86.0%and 81.1%for the control qubit being prepared in|0>and|1>,respectively.We also show that our scheme can be readily extended to realize a general CCZS gate with an arbitrary swap angle.The results reported here provide valuable additions to the toolbox for achieving large-scale hardware-efficient quantum circuits.展开更多
BACKGROUND Here we present a rare case of localized amyloidosis involving the nasolacrimal duct and lacrimal sac which was managed by endoscopic surgery.CASE SUMMARY A 50-year-old man whose medical history included bi...BACKGROUND Here we present a rare case of localized amyloidosis involving the nasolacrimal duct and lacrimal sac which was managed by endoscopic surgery.CASE SUMMARY A 50-year-old man whose medical history included bilateral ventricular fold and vocal cord amyloidosis complained of bilateral epiphora.Magnetic resonance imaging revealed a neoplasm within the nasolacrimal sac.Characteristic positivity for Congo red staining and birefringence under a polarized microscope proved the diagnosis of amyloidosis.Dacryocystorhinostomy via an endoscope obtained a favorable result.A one-year follow-up found no recurrence.CONCLUSION There are few reports on amyloidosis involving the lacrimal outflow system,and management and outcome are not clear.Endoscopic dacryocystorhinostomy can be a choice to relieve symptoms.Regular follow-up and monitoring of systemic diseases are highly recommended.展开更多
文摘To the Editor:Glaucoma is the primary cause of irreversible blindness. Surgery is the main treatment option if intraocular pressure (IOP) cannot be controlled with medications. Local fibroblast proliferation and collagen deposition cause stenosis of drainage channels and scar formation in the filtration area, which are the main causes of unsuccessful antiglaucoma surgery. Application of mitomycin C during surgery is one of the most widely performed clinical interventions aimed at modifying the wound healing process. However, recent reports suggest that there is scope to further improve the outcomes of mitomycin C application in surgery.
基金supported by the Key-Area Research and Development Program of Guangdong Province(No.2018B030326001)the National Natural Science Foundation of China(Nos.12074166 and 12004162)the Guangdong Provincial Key Laboratory(No.2019B121203002).
文摘While the common practice of decomposing general quantum algorithms into a collection of single-and two-qubit gates is conceptually simple,in many cases it is possible to have more efficient solutions where quantum gates engaging multiple qubits are used.In the noisy intermediate-scale quantum(NISQ)era where a universal error correction is still unavailable,this strategy is particularly appealing since it can significantly reduce the computational resources required for executing quantum algorithms.In this work,we experimentally investigate a three-qubit ControlledCPHASE-SWAP(CCZS)gate on superconducting quantum circuits.By exploiting the higher energy levels of superconducting qubits,we are able to realize a Fredkin-like CCZS gate with a duration of 40 ns,which is comparable to typical single-and two-qubit gates realized on the same platform.By performing quantum process tomography for the two target qubits,we obtain a process fidelity of86.0%and 81.1%for the control qubit being prepared in|0>and|1>,respectively.We also show that our scheme can be readily extended to realize a general CCZS gate with an arbitrary swap angle.The results reported here provide valuable additions to the toolbox for achieving large-scale hardware-efficient quantum circuits.
基金Supported by the General Program of Shanghai Municipal Health Commission,No.201940143and Youth Program of National Nature Science Foundation of China,No.81800897.
文摘BACKGROUND Here we present a rare case of localized amyloidosis involving the nasolacrimal duct and lacrimal sac which was managed by endoscopic surgery.CASE SUMMARY A 50-year-old man whose medical history included bilateral ventricular fold and vocal cord amyloidosis complained of bilateral epiphora.Magnetic resonance imaging revealed a neoplasm within the nasolacrimal sac.Characteristic positivity for Congo red staining and birefringence under a polarized microscope proved the diagnosis of amyloidosis.Dacryocystorhinostomy via an endoscope obtained a favorable result.A one-year follow-up found no recurrence.CONCLUSION There are few reports on amyloidosis involving the lacrimal outflow system,and management and outcome are not clear.Endoscopic dacryocystorhinostomy can be a choice to relieve symptoms.Regular follow-up and monitoring of systemic diseases are highly recommended.
