AIM： To investigate preoperative factors associated with poor shore-term outcome after resection for multi- nodular hepatocellular carcinoma （HCC） and to assess the contraindication of patients for surgery, METHODS...AIM： To investigate preoperative factors associated with poor shore-term outcome after resection for multi- nodular hepatocellular carcinoma （HCC） and to assess the contraindication of patients for surgery, METHODS： We retrospectively analyzed 162 multi- nodular HCC patients with Child-Pugh A liver function who underwent surgical resection. The prognostic significance of preoperative factors was investigated by univariate analysis using the log-rank test and by multivariate analysis using the Cox proportional hazards model. Each independent risk factor was then assigned points to construct a scoring model to evaluate the in- dication for surgical intervention. A receiver operating characteristics （ROC） curve was constructed to assess the predictive ability of this system.RESULTS： The median overall survival was 38.3 mo （range： 3-80 too）, while the median disease-free sur- vival was 18.6 mo （range： 1-79 too）. The 1-year mor- tality was 14%. Independent prognostic risk factors of 1-year death included prealburnin 〈 170 rng/L [hazard ratio （HR）： 5.531, P 〈 0.001], alkaline phosphatase 〉 129 U/L （HR： 3.252, P = 0.005）, α fetoprotein 〉 20 μg/L （HR： 7.477, P = 0.011）, total tumor size 〉 8 cm （HR： 10.543; P 〈 0.001）, platelet count 〈 100×109/L （HR： 9.937, P 〈 0.001）, and y-glutamyl transpeptidase 〉 64 U/L （HR： 3.791, P 〈 0.001）. The scoring model had a strong ability to predict 1-year survival （area under ROC： 0.925, P 〈 0.001）. Patients with a score ≥5 had significantly poorer short-term outcome than those with a score 〈 5 （1-year mortality： 62% vs 5%, P 〈 0.001; 1-year recurrence rate： 86% vs 33%, P 〈 0.001）. Patients with score ≥5 had greater possibility of microvascular invasion （P 〈 0.001）, poor tumor dif- ferentiation （P = 0.003）, liver cirrhosis with small nod- ules （P 〈 0.001）, and intraoperative blood transfusion （P = 0.010）. CONCLUSION： A composite preoperative scoring model can 展开更多
The welding heat source models and the plastic tension zone sizes of a typical weld joint involved in the double floor structure of high speed train under different welding parameters were calculated by a thermal-elas...The welding heat source models and the plastic tension zone sizes of a typical weld joint involved in the double floor structure of high speed train under different welding parameters were calculated by a thermal-elastic-plastic FEM analysis based on SYSWELD code.Then,the welding distortion of floor structure was predicted using a linear elastic FEM and shrinkage method based on Weld Planner software.The effects of welding sequence,clamping configuration and reverse deformation on welding distortion of floor structure were examined numerically.The results indicate that the established elastic FEM model for floor structure is reliable for predicting the distribution of welding distortion in view of the good agreement between the calculated results and the measured distortion for real double floor structure.Compared with the welding sequence,the clamping configuration and the reverse deformation have a significant influence on the welding distortion of floor structure.In the case of30 mm reverse deformation,the maximum deformation can be reduced about 70%in comparison to an actual welding process.展开更多
Inflammatory fibroid polyp （IFP） is a group of rare benign mesenchymal tumors throughout the gastrointestinal tract.The most involved sites are stomach and large intestines,followed by small intestines,esophagus,and...Inflammatory fibroid polyp （IFP） is a group of rare benign mesenchymal tumors throughout the gastrointestinal tract.The most involved sites are stomach and large intestines,followed by small intestines,esophagus,and anal canal.However,even in the stomach,its incidence is only 0.1% of all gastric polyps.[1] We here reported an IFP located in the cecum.展开更多
The residual stress evolution in a safe-end/nozzle dissimilar metal welded joint of CAP1400 nuclear power plants was investigated in the manufacturing process by finite element simulation. A finite element model, incl...The residual stress evolution in a safe-end/nozzle dissimilar metal welded joint of CAP1400 nuclear power plants was investigated in the manufacturing process by finite element simulation. A finite element model, including cladding,buttering, post-weld heat treatment (PWHT) and dissimilar metal multi-pass welding, is developed based on SYSWELD software to investigate the evolution of residual stress in the aforementioned manufacturing process. The results reveal a large tensile axial residual stress, which exists at the weld zone on the inner surface, leads to a high sensitivity to stress corrosion cracking (SCC). PWHT process before dissimilar metal multi-pass welding process has a great in?uence on the magnitude and distribution of final axial residual stress. The risk of SCC on the inner surface of the pipe will increase if PWHT process is not taken into account. Therefore, such crucial thermal manufacturing process such as cladding, buttering and post-weld heat treatment, besides the multi-pass welding process, should be considered in the numerical model in order to accurately predict the distribution and the magnitude of the residual stress.展开更多
文摘AIM： To investigate preoperative factors associated with poor shore-term outcome after resection for multi- nodular hepatocellular carcinoma （HCC） and to assess the contraindication of patients for surgery, METHODS： We retrospectively analyzed 162 multi- nodular HCC patients with Child-Pugh A liver function who underwent surgical resection. The prognostic significance of preoperative factors was investigated by univariate analysis using the log-rank test and by multivariate analysis using the Cox proportional hazards model. Each independent risk factor was then assigned points to construct a scoring model to evaluate the in- dication for surgical intervention. A receiver operating characteristics （ROC） curve was constructed to assess the predictive ability of this system.RESULTS： The median overall survival was 38.3 mo （range： 3-80 too）, while the median disease-free sur- vival was 18.6 mo （range： 1-79 too）. The 1-year mor- tality was 14%. Independent prognostic risk factors of 1-year death included prealburnin 〈 170 rng/L [hazard ratio （HR）： 5.531, P 〈 0.001], alkaline phosphatase 〉 129 U/L （HR： 3.252, P = 0.005）, α fetoprotein 〉 20 μg/L （HR： 7.477, P = 0.011）, total tumor size 〉 8 cm （HR： 10.543; P 〈 0.001）, platelet count 〈 100×109/L （HR： 9.937, P 〈 0.001）, and y-glutamyl transpeptidase 〉 64 U/L （HR： 3.791, P 〈 0.001）. The scoring model had a strong ability to predict 1-year survival （area under ROC： 0.925, P 〈 0.001）. Patients with a score ≥5 had significantly poorer short-term outcome than those with a score 〈 5 （1-year mortality： 62% vs 5%, P 〈 0.001; 1-year recurrence rate： 86% vs 33%, P 〈 0.001）. Patients with score ≥5 had greater possibility of microvascular invasion （P 〈 0.001）, poor tumor dif- ferentiation （P = 0.003）, liver cirrhosis with small nod- ules （P 〈 0.001）, and intraoperative blood transfusion （P = 0.010）. CONCLUSION： A composite preoperative scoring model can
基金financial support to this project from the Chinese CSR Qingdao Sifang Co.,Ltd
文摘The welding heat source models and the plastic tension zone sizes of a typical weld joint involved in the double floor structure of high speed train under different welding parameters were calculated by a thermal-elastic-plastic FEM analysis based on SYSWELD code.Then,the welding distortion of floor structure was predicted using a linear elastic FEM and shrinkage method based on Weld Planner software.The effects of welding sequence,clamping configuration and reverse deformation on welding distortion of floor structure were examined numerically.The results indicate that the established elastic FEM model for floor structure is reliable for predicting the distribution of welding distortion in view of the good agreement between the calculated results and the measured distortion for real double floor structure.Compared with the welding sequence,the clamping configuration and the reverse deformation have a significant influence on the welding distortion of floor structure.In the case of30 mm reverse deformation,the maximum deformation can be reduced about 70%in comparison to an actual welding process.
文摘Inflammatory fibroid polyp （IFP） is a group of rare benign mesenchymal tumors throughout the gastrointestinal tract.The most involved sites are stomach and large intestines,followed by small intestines,esophagus,and anal canal.However,even in the stomach,its incidence is only 0.1% of all gastric polyps.[1] We here reported an IFP located in the cecum.
基金supported by the Open-ended Fund of the CAS Key Laboratory of Nuclear Materials and Safety Assessment (Grant No. 2015NMSAKF02)
文摘The residual stress evolution in a safe-end/nozzle dissimilar metal welded joint of CAP1400 nuclear power plants was investigated in the manufacturing process by finite element simulation. A finite element model, including cladding,buttering, post-weld heat treatment (PWHT) and dissimilar metal multi-pass welding, is developed based on SYSWELD software to investigate the evolution of residual stress in the aforementioned manufacturing process. The results reveal a large tensile axial residual stress, which exists at the weld zone on the inner surface, leads to a high sensitivity to stress corrosion cracking (SCC). PWHT process before dissimilar metal multi-pass welding process has a great in?uence on the magnitude and distribution of final axial residual stress. The risk of SCC on the inner surface of the pipe will increase if PWHT process is not taken into account. Therefore, such crucial thermal manufacturing process such as cladding, buttering and post-weld heat treatment, besides the multi-pass welding process, should be considered in the numerical model in order to accurately predict the distribution and the magnitude of the residual stress.
