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中国野生动物红外相机监测与研究:现状及未来 被引量:37
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作者 肖治术 肖文宏 +5 位作者 王天明 李晟 连新明 宋大昭 邓雪琴 周岐海 《生物多样性》 CAS CSCD 北大核心 2022年第10期230-255,共26页
智能传感器、人工智能、信息技术等现代科学技术的创新应用极大地提升了人类在全球生物多样性保护和恢复方面的潜力。结合国内外相关研究案例,本文的主要内容包括:(1)对过去30年间(1991–2021年)中国野生动物红外相机监测研究相关文献... 智能传感器、人工智能、信息技术等现代科学技术的创新应用极大地提升了人类在全球生物多样性保护和恢复方面的潜力。结合国内外相关研究案例,本文的主要内容包括:(1)对过去30年间(1991–2021年)中国野生动物红外相机监测研究相关文献资料进行总结分析;(2)结合国内2011年以来的典型案例,对技术方法、物种发现与编目、形态与行为研究、生态学研究和保护管理等主题领域的进展进行总结分析;(3)结合国外近期的典型案例,对红外相机监测与研究的重点领域进行评估分析;(4)对中国野生动物红外相机监测研究的未来发展提出相关建议。通过回顾,本文旨在明晰国内外红外相机技术在野生动物监测研究中的创新应用和发展趋势,为中国在该领域的未来发展提供参考依据,以便更好地服务于中国生物多样性监测与研究网络建设和以国家公园为主体的自然保护地体系建设,为推进国家生态文明建设、保障生态安全和生物安全提供决策支持和科学依据。 展开更多
关键词 红外相机技术 野生动物监测 物种编目 动物行为 生态学 保护管理 自然保护地
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基于光纤布喇格光栅的配电变压器分布式温度监测方法 被引量:10
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作者 王利 杨红磊 +3 位作者 秦炜淇 廖天明 宋祺鹏 马国明 《广东电力》 2019年第1期152-157,共6页
配电变压器在运行过程中由于动态增容需要、配电网三相不平衡的影响、变压器结构设计优化需要等因素,绕组会出现温升热点,加速绝缘老化,降低变压器使用寿命;而配电变压器绕组热点温度监测对于确保其安全稳定运行具有重要意义。为实现对... 配电变压器在运行过程中由于动态增容需要、配电网三相不平衡的影响、变压器结构设计优化需要等因素,绕组会出现温升热点,加速绝缘老化,降低变压器使用寿命;而配电变压器绕组热点温度监测对于确保其安全稳定运行具有重要意义。为实现对配电变压器绕组温度准确监测,提出一种基于光纤布喇格光栅的配电变压器分布式温度监测方法,首先介绍了光纤布喇格光栅测温原理;其次基于COMSOL有限元仿真软件对10 kV配电变压器温度场分布进行仿真计算,得到绕组温升热点位置,并据此设计出光纤光栅温度传感器布置方案;最后通过改进制造工艺,研制出基于光纤布喇格光栅的分布式温度监测配电变压器样机,并进行了额定负载条件下的温升试验。试验结果表明,绕组热点分布与仿真结果相符。 展开更多
关键词 光纤布喇格光栅 分布式温度监测 配电变压器 有限元仿真 热点温度
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基于后倾斜高抽巷为主体的坚硬顶板综放工作面初采期瓦斯综合治理 被引量:10
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作者 张利军 张东鹏 +4 位作者 张天明 罗仁俊 张超 宋一帆 杨胜强 《煤矿安全》 CAS 北大核心 2021年第12期73-77,共5页
通过分析漳村矿2601综放工作面初采期瓦斯骤然异常涌出现象及其变化规律,拟在2603综放工作面采用顶板预裂减少初次来压步距、切眼处打钻贯通后倾斜高抽巷提前抽采瓦斯,以及随瓦斯涌出量的增加而增加供风量等技术措施,消除初采期的骤然... 通过分析漳村矿2601综放工作面初采期瓦斯骤然异常涌出现象及其变化规律,拟在2603综放工作面采用顶板预裂减少初次来压步距、切眼处打钻贯通后倾斜高抽巷提前抽采瓦斯,以及随瓦斯涌出量的增加而增加供风量等技术措施,消除初采期的骤然瓦斯异常涌出现象,彻底解决综放工作面初采期瓦斯超限的问题。结果表明:基于后倾斜高抽巷为主体的、由顶板预裂、切眼处打钻贯通后倾斜高抽巷及增加风量等所组成的初采期瓦斯治理技术体系,消除了初采期的骤然瓦斯涌出现象,解决了初采期的瓦斯超限问题。 展开更多
关键词 坚硬顶板 初采期 初次来压 瓦斯异常涌出 后倾斜高抽巷
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Measurement of 2p-3d absorption in a hot molybdenum plasma
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作者 Gang Xiong Bo Qing +17 位作者 Zhiyu Zhang Longfei Jing Yang Zhao Minxi Wei Yimeng Yang Lifei Hou Chengwu Huang Tuo Zhu tianming song Min Lv Yan Zhao Yuxue Zhang Guohong Yang Zeqing Wu Jun Yan Yaming Zou Jiyan Zhang Jiamin Yang 《Matter and Radiation at Extremes》 SCIE EI CSCD 2024年第4期68-79,共12页
We present measurements of the 2p-3d transition opacity of a hot molybdenum-scandium sample with nearly half-vacant molybdenum M-shell configurations.A plastic-tamped molybdenum-scandium foil sample is radiatively hea... We present measurements of the 2p-3d transition opacity of a hot molybdenum-scandium sample with nearly half-vacant molybdenum M-shell configurations.A plastic-tamped molybdenum-scandium foil sample is radiatively heated to high temperature in a compact D-shaped gold Hohlraum driven by∼30 kJ laser energy at the SG-100 kJ laser facility.X rays transmitted through the molybdenum and scandium plasmas are diffracted by crystals and finally recorded by image plates.The electron temperatures in the sample in particular spatial and temporal zones are determined by the K-shell absorption of the scandium plasma.A combination of the IRAD3D view factor code and the MULTI hydrodynamic code is used to simulate the spatial distribution and temporal behavior of the sample temperature and density.The inferred temperature in the molybdenum plasma reaches a average of 138±11 eV.A detailed configuration-accounting calculation of the n=2–3 transition absorption of the molybdenum plasma is compared with experimental measurements and quite good agreement is found.The present measurements provide an opportunity to test opacity models for complicated M-shell configurations. 展开更多
关键词 MOLYBDENUM ABSORPTION CONFIGURATION
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Self-consistent and precise measurement of time-dependent radiative albedo of gold based on specially symmetrical triple-cavity Hohlraum
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作者 Zhiyu Zhang Yang Zhao +19 位作者 Xiaoying Han Liling Li Bo Qing Lifei Hou Yulong Li YuXue Zhang Huan Zhang Xiangming Liu Bo Deng Gang Xiong Min Lv Tuo Zhu Chengwu Huang tianming song Yan Zhao Yingjie Li Lu Zhang Xufei Xie Jiyan Zhang Jiamin Yang 《Matter and Radiation at Extremes》 SCIE EI CSCD 2024年第3期57-64,共8页
A self-consistent and precise method to determine the time-dependent radiative albedo,i.e.,the ratio of the reemission flux to the incident flux,for an indirect-drive inertial confinement fusion Hohlraum wall material... A self-consistent and precise method to determine the time-dependent radiative albedo,i.e.,the ratio of the reemission flux to the incident flux,for an indirect-drive inertial confinement fusion Hohlraum wall material is proposed.A specially designed symmetrical triple-cavity gold Hohlraum is used to create approximately constant and near-equilibrium uniform radiation with a peak temperature of 160 eV.The incident flux at the secondary cavity waist is obtained from flux balance analysis and from the shock velocity of a standard sample.The results agree well owing to the symmetrical radiation in the secondary cavity.A self-consistent and precise time-dependent radiative albedo is deduced from the reliable reemission flux and the incident flux,and the result from the shock velocity is found to have a smaller uncertainty than that from the multi-angle flux balance analysis,and also to agree well with the result of a simulation using the HYADES opacity. 展开更多
关键词 PRECISE cavity RADIATIVE
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Synergistic functionalization of poly(p-terphenyl isatin) anion exchange membrane with quaternary ammonium and piperidine cations for fuel cells
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作者 Yiman Gu Yanchao Zhang +7 位作者 Zhe Wang Di Liu Yan Wang tianming Dong song Wang Zhanyu Li Jingyi Wu Yijia Lei 《Industrial Chemistry & Materials》 2024年第1期141-153,共13页
Research on anion exchange membrane fuel cells(AEMFCs)mainly focuses on the membrane module,and improving its performance has always been the focus of researchers.To create high-performance anion exchange membranes(AE... Research on anion exchange membrane fuel cells(AEMFCs)mainly focuses on the membrane module,and improving its performance has always been the focus of researchers.To create high-performance anion exchange membranes(AEMs),a series of side chain type AEMs were prepared by introducing different proportions of side chains containing anisotropic poly cations with relatively stable piperidinium ring cations and side quaternary ammonium cations as cation groups,using poly(p-terphenyl isatin)(PTI),a main chain polymer without aryl ether bonds.The dense surface of the PTI-N-n series membranes is shown by SEM images;TEM images show that the ion domains are clearly distributed in the membrane,so a continuous ion transport channel is constructed.PTI-N-100 has the highest hydroxide conductivity at 80℃,reaching 96.83 mS cm^(-1) due to multiple transport sites.The PTI-N-100 membrane has a peak power density of 180 mW cm^(2) based on the highest ionic conductivity.Therefore,we believe that the introduction of multi-cations contributes to the performance of anion exchange membranes. 展开更多
关键词 Multi-cation Ether-free polymer Alkaline resistance Microphase separation
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Laboratorial radiative shocks with multiple parameters and first quantifying verifications to core-collapse supernovae
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作者 Lu Zhang Jianhua Zheng +20 位作者 Zhenghua Yang tianming song Shuai Zhang Tong Liu Yunfeng Wei Longyu Kuang Longfei Jing Zhiwei Lin Liling Li Hang Li Jinhua Zheng Pin Yang Yuxue Zhang Zhiyu Zhang Yang Zhao Zhibing He Ping Li Dong Yang Jiamin Yang Zongqing Zhao Yongkun Ding 《Science Bulletin》 SCIE EI CAS CSCD 2024年第20期3188-3191,共4页
A radiative shock(RS)is one in which the density and temperature structures are affected by radiation from the shock-heated matter.RS plays a special role in astrophysics as it nontrivially combines both hydrodynamics... A radiative shock(RS)is one in which the density and temperature structures are affected by radiation from the shock-heated matter.RS plays a special role in astrophysics as it nontrivially combines both hydrodynamics and radiation physics.In most astrophysical shocks,the temperature and density conditions lead to strong emission,with radiation thus playing a major role therein. 展开更多
关键词 SHOCKS RADIATIVE shock
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Tamping the movement of the laser absorption cutoff position using gold foam hohlraum
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作者 张璐 李丽灵 +14 位作者 林稚伟 董云松 景龙飞 郑建华 况龙钰 黎航 郑金华 张继彦 宋天明 张志宇 赵阳 牛高 杨冬 杨家敏 丁永坤 《Plasma Science and Technology》 SCIE EI CAS CSCD 2024年第5期56-61,共6页
In indirect-driven laser fusion experiments,the movement of the laser absorption layer will distort the radiation uniformity on the capsule.The gold foam has advantages in symmetry control and lowering wall plasma blo... In indirect-driven laser fusion experiments,the movement of the laser absorption layer will distort the radiation uniformity on the capsule.The gold foam has advantages in symmetry control and lowering wall plasma blowoff when used in an inertial confinement fusion(ICF)hohlraum.This work investigates the motion of the laser absorption cutoff position using lowdensity foam gold walls.It is found that the motion of the laser absorption cutoff position can be significantly mitigated through optimal initial low density,tailored to a specific laser shape.For a short square laser pulse,the laser absorption cutoff position remains almost stationary at an initial density of approximately 0.6 g cm^(-3).For a long-shaped laser pulse,the minimal motion of the laser absorption cutoff position is observed at an initial density of about 0.1 g cm^(-3).This approach allows for the adjustment of the symmetry of the hohlraum radiation source.The insights gained from this study serve as a crucial reference for optimizing the hohlraum wall density. 展开更多
关键词 hohlraum symmetry laser absorption plasma blowoff gold foam
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Theoretical investigations on x-ray transport in radiation transport experiments on the Shenguang-Ⅲ prototype laser facility 被引量:3
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作者 Guangwei Meng Jun She +2 位作者 tianming song Jiamin Yang Min Wang 《Matter and Radiation at Extremes》 SCIE EI CAS CSCD 2022年第2期25-32,共8页
Experiments exploring the propagation of heat waves within cylindrical CH foams were performed on the Shenguang-Ⅲ prototype laser facility in 2012.In this paper,the radiation fluxes out of CH foam cylinders at differ... Experiments exploring the propagation of heat waves within cylindrical CH foams were performed on the Shenguang-Ⅲ prototype laser facility in 2012.In this paper,the radiation fluxes out of CH foam cylinders at different angles are analyzed theoretically using the two-dimensional radiation hydrodynamics code LARED-R.Owing to the difficulty in validating opacity and equation of state(EOS)data for high-Z plasmas,and to uncertainties in the measured radiation temperature Tr and the original foam densityρ0,multipliers are introduced to adjust the Au material parameters,Tr,andρ0 in our simulations to better explain the measurements.The dependences of the peak radiation flux Fmax and the breakout time of the heat wave thalf(defined as the time corresponding to the radiation flux at half-maximum)on the radiation source,opacity,EOS,andρ0 scaling factors(η_(src),η_(op),η_(eos),and η_(ρ))are investigated via numerical simulations combined with fitting.Then,with the uncertainties in the measured Tr andρ0 fixed at 3.6%and 3.1%,respectively,experimental data are exploited as fiducial values to determine the ranges ofη_(op) andηeos.It is found that the ranges ofη_(op) andηeos fixed by this experiment overlap partially with those found in our previous work[Meng et al.,Phys.Plasmas 20,092704(2013)].Based on the scaled opacity and EOS parameters,the values of F_(max) and t_(half) obtained via simulations are in good agreement with the measurements,with maximum errors∼9.5%and within 100 ps,respectively. 展开更多
关键词 CYLINDRICAL OVERLAP ADJUST
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修正内梅罗污染指数法在广州市河涌水质评价中的应用 被引量:3
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作者 杨慧文 董天明 +3 位作者 王丽萍 杨宇 宋惠莹 陈漾 《广东化工》 CAS 2018年第11期64-66,83,共4页
河流水质评价是水环境治理的重要基础工作。对于污染严重的河流(如劣Ⅴ类水质),水质往往经过长期的整治仍未发生好转,现行的水质评价方法不能反映水质在不同时段的变化趋势。本论文提出了利用修正内梅罗污染指数法对广州市典型河涌水质... 河流水质评价是水环境治理的重要基础工作。对于污染严重的河流(如劣Ⅴ类水质),水质往往经过长期的整治仍未发生好转,现行的水质评价方法不能反映水质在不同时段的变化趋势。本论文提出了利用修正内梅罗污染指数法对广州市典型河涌水质进行综合评价,并将其与单因子评价法及传统内梅罗污染指数法进行对比研究。结果表明,修正内梅罗污染指数法能够有效评价广州市河涌水质的污染现状和变化趋势,突显河涌长期治理成效。该方法为广州市河涌综合整治效果评估提供理论指导和技术支撑。 展开更多
关键词 河涌水质 内梅罗污染指数 单因子评价法 修正内梅罗污染指数
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原位限域Ru-SiO2的制备及其氨分解性能研究 被引量:2
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作者 聂天明 宋文静 +2 位作者 赵佳文 邓黎丹 姜兴茂 《化工新型材料》 CAS CSCD 北大核心 2020年第8期203-207,共5页
以葡萄糖、尿素、氯化钌和硅溶胶为前驱体,葡萄糖碳化后作为碳模板,利用微波辅助将Ru纳米颗粒限域负载于介孔SiO2之上,焙烧后得到高度均匀分散的Ru-SiO2材料。通过XRD、TEM和BET等表征手段对材料的结构形貌进行了分析,以热催化氨分解反... 以葡萄糖、尿素、氯化钌和硅溶胶为前驱体,葡萄糖碳化后作为碳模板,利用微波辅助将Ru纳米颗粒限域负载于介孔SiO2之上,焙烧后得到高度均匀分散的Ru-SiO2材料。通过XRD、TEM和BET等表征手段对材料的结构形貌进行了分析,以热催化氨分解反应作为评价体系,对样品进行了催化活性评价。实验表明,此法制备的材料较浸渍法具有更好的催化活性,在相同温度下有更高的转化率。这主要是归因于SiO2载体对活性组分Ru的限域作用,使得Ru颗粒具有较小、均匀的粒径,以及良好的热稳定性。 展开更多
关键词 Ru-二氧化硅 原位合成 碳模板 氨分解
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高光谱协同稀疏与非局部低秩张量变化检测 被引量:2
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作者 詹天明 宋博 +2 位作者 孙乐 万鸣华 杨国为 《计算机科学与探索》 CSCD 北大核心 2022年第2期448-457,共10页
高光谱图像变化检测可提供地球表面的时间维变化信息,对城乡规划和管理至关重要。因具有较高的光谱分辨率,高光谱图像常被用于检测更精细的变化。针对高光谱变化检测的问题,提出一种基于协同稀疏与非局部低秩张量的高光谱图像变化检测... 高光谱图像变化检测可提供地球表面的时间维变化信息,对城乡规划和管理至关重要。因具有较高的光谱分辨率,高光谱图像常被用于检测更精细的变化。针对高光谱变化检测的问题,提出一种基于协同稀疏与非局部低秩张量的高光谱图像变化检测方法。该方法首先求得前后时间点的高光谱差分图像,再根据差分图像中图像块的非局部分布特点,提取不同的非局部张量簇。然后基于协同稀疏正则化和低秩正则化建立协同稀疏与非局部低秩张量变化检测模型,并采用交替方向乘子法对模型求解得到表示系数。最后根据表示系数求得张量在不同类别中的投影残差,进而根据投影残差最小准则判断该张量块是否发生变化。在Farmland数据集和Urban area in San Francisco City数据集上进行实验,实验结果表明该方法取得较好的高光谱变化检测精度。 展开更多
关键词 高光谱 变化检测 协同稀疏 非局部低秩 张量分解
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基于科教融合理念探讨高等医药院校生物化学教学 被引量:1
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作者 汪天明 马克龙 +2 位作者 李璐 宋航 蔡标 《宿州学院学报》 2023年第9期77-80,共4页
以“传承精华,守正创新”的创新型人才培养要求为导向,践行“科教融合、协同育人”的理念为主题,努力实现科教融合促进创新人才培养。文本分析了医药院校生物化学教学中采用科教融合的必要性,生物化学课程教学的现状和教学中面临的问题... 以“传承精华,守正创新”的创新型人才培养要求为导向,践行“科教融合、协同育人”的理念为主题,努力实现科教融合促进创新人才培养。文本分析了医药院校生物化学教学中采用科教融合的必要性,生物化学课程教学的现状和教学中面临的问题和挑战,以及实施科教融合的主要策略及建议。为不断提高医药类本科人才质量提供新的思路和策略。 展开更多
关键词 科教融合 医药院校 生物化学
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Optimization of process parameters for preparation of powdered activated coke to achieve maximum SO_(2)adsorption using response surface methodology 被引量:1
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作者 Binxuan ZHOU Tao WANG +6 位作者 tianming XU Cheng LI Yuan ZHAO Jiapeng FU Zhen ZHANG Zhanlong song Chunyuan MA 《Frontiers in Energy》 SCIE CSCD 2021年第1期159-169,共11页
Powdered activated coke(PAC)is a good adsorbent of SO_(2),but its adsorption capacity is affected by many factors in the preparation process.To prepare the PAC with a high SO_(2)adsorption capacity using JJ-coal under... Powdered activated coke(PAC)is a good adsorbent of SO_(2),but its adsorption capacity is affected by many factors in the preparation process.To prepare the PAC with a high SO_(2)adsorption capacity using JJ-coal under flue gas atmosphere,six parameters(oxygen-coal equivalent ratio,reaction temperature,reaction time,O_(2)concentration,CO_(2)concentration,and H_(2)O concentration)were screened and optimized using the response surface methodology(RSM).The results of factor screening experiment show that reaction temperature,O_(2)concentration,and H_(2)O(g)concentration are the significant factors.Then,a quadratic polynomial regression model between the significant factors and SO_(2)adsorption capacity was established using the central composite design(CCD).The model optimization results indicate that when reaction temperature is 904.74℃,O_(2)concentration is 4.67%,H_(2)O concentration is 27.98%,the PAC(PAC-OP)prepared had a higher SO_(2)adsorption capacity of 68.15 mg/g while its SO_(2)adsorption capacity from a validation experiment is 68.82 mg/g,and the error with the optimal value is 0.98%.Compared to two typical commercial activated cokes(ACs),PAC-OP has relatively more developed pore structures,and its SBET and Vtot are 349 m^(2)/g and 0.1475 cm3/g,significantly higher than the 186 m^(2)/g and 0.1041 cm3/g of AC1,and the 132 m^(2)/g and 0.0768 cm3/g of AC2.Besides,it also has abundant oxygen-containing functional groups,its surface O content being 12.09%,higher than the 10.42%of AC1 and 10.49%of AC2.Inevitably,the SO_(2)adsorption capacity of PAC-OP is also significantly higher than that of both AC1 and AC2,which is 68.82 mg/g versus 32.53 mg/g and 24.79 mg/g,respectively. 展开更多
关键词 powdered activated coke(PAC) S0_(2)adsorption capacity parameters optimization response surface methodology
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Effect of casting technology on microstructure and phases of high carbon high speed steel 被引量:1
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作者 Zhang tianming Wang Qinjuan +1 位作者 song Xuding Fu Hanguang 《China Foundry》 SCIE CAS 2011年第2期197-201,共5页
The as-cast microstructures of high carbon high speed steels (HC-HSS) made by sand casting, centrifugal casting and electromagnetic centrifugal casting, respectively, were studied by using of optical microscopy (OM... The as-cast microstructures of high carbon high speed steels (HC-HSS) made by sand casting, centrifugal casting and electromagnetic centrifugal casting, respectively, were studied by using of optical microscopy (OM) and D/max2200pc X-ray diffraction. The results show that the microstructure of as-cast HC- HSS is dominated by alloy carbides (W2C, VC, Cr7C3), martensite and austenite. The centrifugal casting and electromagnetic centrifugal casting apparently improve the solidification structure of HCoHSS. With the increase of magnetic intensity (B), the volume fraction of austenite in the HC-HSS solidification structure increases significantly while the eutectic ledeburite decreases. Moreover, the secondary carbides precipitated from the austenite are finer with more homogeneous distribution in the electromagnetic centrifugal castings. It has also been found that the lath of eutectic carbide in ledeburite becomes finer and carbide phase spacing in eutectic ledeburite increases along with the higher magnetic field strength. 展开更多
关键词 high carbon high speed steel electromagnetic centrifugal casting solidification structure PHASE
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航空发动机整机变形仿真的自动化技术应用
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作者 白天明 宋学舟 +1 位作者 李勇 孙宝龙 《今日自动化》 2023年第2期115-117,共3页
航空发动机的仿真对象模型规模大,简化处理繁琐,每次模型计算重复工作量很大,甚至仿真效率极低,有时对项目进度会产生延期影响,总的来说,现有仿真业务及其管理的需求越来越复杂,对综合仿真工作提出了更高的要求。为提高仿真效率及日常... 航空发动机的仿真对象模型规模大,简化处理繁琐,每次模型计算重复工作量很大,甚至仿真效率极低,有时对项目进度会产生延期影响,总的来说,现有仿真业务及其管理的需求越来越复杂,对综合仿真工作提出了更高的要求。为提高仿真效率及日常设计和管理工作的需要,开发了一套综合仿真自动化技术,以适应新的软件硬件环境并满足跨部门协同办公,将大部分工作转成自动化,减少人工投入,从而提高工作效率,缩短仿真项目计算周期。 展开更多
关键词 航空发动机 仿真 自动化
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New norlignan enantiomers from the fruit of Crataegus pinnatifida with neuroprotective activities 被引量:1
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作者 Rui Guo tianming Lv +6 位作者 Fengying Han Zilin Hou Guodong Yao Bin Lin Xiaobo Wang Xiaoxiao Huang Shaojiang song 《Chinese Chemical Letters》 SCIE CAS CSCD 2020年第5期1254-1258,共5页
(±)-Crataegusnorin A(la/1b) and B(2a/2b),two pairs of rare 8,9’-epoxy-type norlignan enantiomers featuring a y-butyrolactone ring,were isolated from the fruit of Crataegus pinnatifida.Their structures were deter... (±)-Crataegusnorin A(la/1b) and B(2a/2b),two pairs of rare 8,9’-epoxy-type norlignan enantiomers featuring a y-butyrolactone ring,were isolated from the fruit of Crataegus pinnatifida.Their structures were determined via extensive spectroscopic analyses.Gauge-independent atomic orbital(GIAO) NMR chemical shift calculations,combined with the advanced statistical method DP4+were employed to establish the relative configurations of four compounds.Next,chiral separation was accomplished by chiral chromatographic column and the absolute configurations of the four compounds were unambiguously assigned by comparison between their experimental electronic circular dichroism curves with the quantum-mechanically calculated curves based on time-dependent density functional theory(TDDFT).All the isolates were evaluated fo r their neuroprotective activities against H2O2-induced cell injury in human neuroblastoma SH-SY5Y cells.The results showed that two pairs of enantiomers 1a/1b and 2a/2b displayed diff;erent effect on neuroprotective activity.Among them,compound 2a displayed the most potent neuroprotective effect Further flow cytometry analysis indicated that 2a could protect SH-SY5Y cells from oxidative damage through inhibiting cell apoptosis. 展开更多
关键词 Crataegus pinnatifida Norlignan enantiomer Neuroprotective activity SH-SY5Y cells Apoptosis
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Study on direct point spread function measurement of capillary plate collimators with divergent X-ray beams
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作者 tianming Li Tao Luo +2 位作者 Yupeng Xu Huilin He Liming song 《Radiation Detection Technology and Methods》 CSCD 2023年第3期321-336,共16页
Purpose The Filed of View(FOV)of eXTP/LAD is limited by lead-glass capillary plate collimators placed in front of the Silicon Drift Detectors(SDDs)for reducing the background contamination caused by the photons of Cos... Purpose The Filed of View(FOV)of eXTP/LAD is limited by lead-glass capillary plate collimators placed in front of the Silicon Drift Detectors(SDDs)for reducing the background contamination caused by the photons of Cosmic X-ray Background(CXB)leaking from outside the FOV.The core quality parameters of lead-glass capillary plate collimators are Open Area Ratio(OAR)and FOV.The performance of lead-glass capillary plate collimators is determined by its design specification such as pore-to-pore misalignment,pore perpendicularity with collimator surface and pore diameter.Since the design specification is the result of a large number of micropores,we use the full width at half maximum(FWHM)and peak value of point spread function(PSF)to characterize the capillary plate collimator performance.In order to quickly evaluate the performances of collimators,we developed a direct PSF measurement method using divergent beams.Methods In this paper,the simulation package of the divergent beamsmeasurement setup is developed based on Geant4.The simulation parameters of scintillator absorption length are corrected by experimental data.We simulate the PSF of collimators with different distribution of pore diameter and misalignment by parallel beams and divergent beams.By comparing the peak value and FWHM of collimators PSF,the feasibility in replacing parallel beams measurement with divergent beams measurement is studied.Results It is verified that the influence of the geometric size of 33μm radius of the micro-focus of X-ray tube can be ignored.The results show that the FWHM of collimators is increased with error root mean square error(RMS)of the distribution of collimators pore diameter and pore inclination angle.The peak value of PSF is mainly influenced by pore non-parallelism of the pores,and it decreases with an increase in pore inclination angle.Comparison of parallel beams PSF and divergent beams PSF shows well consistency of peak value and FWHM of collimator.But,the peak value of the divergent beams PSF is mainly affected by 展开更多
关键词 GEANT4 EXTP/LAD Capillary plate collimators Divergent X-ray beams measurment
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金顶超大型铅锌矿床角砾岩分形研究及地质意义
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作者 庄天明 宋玉财 +1 位作者 侯增谦 张翀 《地学前缘》 EI CAS CSCD 北大核心 2020年第2期320-331,共12页
前人研究提出金顶超大型铅锌矿床发育出了多种角砾岩,其成因与盐底辟作用有关。文章对这些角砾岩进行了分形分析,确定了不同角砾岩的角砾形态分维值D_r和粒径大小分维值D_s,来进一步探讨角砾岩的形成过程。其中,D_r表征形态复杂性,可指... 前人研究提出金顶超大型铅锌矿床发育出了多种角砾岩,其成因与盐底辟作用有关。文章对这些角砾岩进行了分形分析,确定了不同角砾岩的角砾形态分维值D_r和粒径大小分维值D_s,来进一步探讨角砾岩的形成过程。其中,D_r表征形态复杂性,可指示角砾迁移距离长短或后化学作用改造情况,D_s表征角砾破碎情况,指示形成角砾的能量大小。研究表明,金顶矿床中一部分角砾岩为蒸发盐或膏砂近原位底辟、破碎灰岩围岩形成,它们具有较小的D_r和D_s值。与这些角砾岩空间过渡的层状砂质胶结灰岩砾角砾岩(或称层状含灰岩角砾砂岩),为蒸发盐而非水流体携带灰岩角砾流出地表,并进入含水沉积系统后形成,角砾未经历水流体搬运、磨圆,具有较小的D_r和较大的D_s值。另外一部分角砾岩为蒸发盐和砂泥质底辟破碎围岩,并共同迁移了一定距离而形成,但总体未发生长距离的迁移,随后进入地表沉积系统中。上述部分角砾岩还经历了形成后的流体交代溶蚀作用,导致D_r值变大。本研究显示,在盐底辟有关铅锌矿床内,赋矿围岩包含多种由不同底辟过程形成的角砾岩。 展开更多
关键词 角砾岩 分形分析 形成过程 金顶
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猪链球菌重组靶向表位蛋白DCpep-GSE的构建及细胞毒性检测
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作者 潘晨浩 张欣 +8 位作者 赵瑞利 姜轩 金天明 于恩远 李留安 曾君 于晓雪 宋淇淇 胡烨 《中国畜牧兽医》 CAS 北大核心 2021年第8期2990-3001,共12页
试验旨在构建pET28a-DCpep-GSE原核表达载体,并制备猪链球菌(Streptococcus suis)重组表位蛋白。应用生物信息学方法预测猪链球菌保护性抗原三磷酸甘油醛脱氢酶(GAPDH)、烯醇化酶(Enolase)、DNA核酸酶(SsnA)的跨膜区结构、信号肽、B细... 试验旨在构建pET28a-DCpep-GSE原核表达载体,并制备猪链球菌(Streptococcus suis)重组表位蛋白。应用生物信息学方法预测猪链球菌保护性抗原三磷酸甘油醛脱氢酶(GAPDH)、烯醇化酶(Enolase)、DNA核酸酶(SsnA)的跨膜区结构、信号肽、B细胞表位、辅助T细胞(Th细胞)表位及蛋白的二级结构;设计重组蛋白(DCpep-GSE蛋白)的氨基酸序列并分析其理论等电点、亲疏水性等理化性质;构建重组原核表达载体pET28a-DCpep-GSE,转化大肠杆菌BL21(DE3)感受态细胞,优化诱导表达条件,His镍柱纯化并检测目的蛋白的细胞毒性和溶血性。结果显示,SsnA蛋白第1-50及1036-1059位氨基酸为胞内或跨膜片段,第1-56位氨基酸为信号肽片段,GAPDH和Enolase无跨膜区及信号肽;B细胞和Th细胞表位处于二级结构中的无规则卷曲与β-转角区域,表位抗原性良好;DCpep-GSE蛋白共373个氨基酸,分子质量为45.3 ku,理论等电点(pI)为4.57,平均亲水性(GRAVY)为-0.677,属于酸性亲水性蛋白;质粒双酶切得到5369 bp的载体条带和1131 bp的目的条带,PCR扩增产物测序结果与设计序列一致,载体构建正确;以1 mmol/L IPTG于37℃诱导6 h蛋白表达量最高,超声破碎后得到可溶性蛋白;试验组蛋白浓度为500μg/mL时,RAW264.7、PK15和MARC145细胞的相对增殖率分别达到92.3%、99.5%和99.7%,细胞形态与对照组一致,生长旺盛;各样品组的溶血率均<5%。本研究设计了重组蛋白DCpep-GSE,成功地表达和纯化了DCpep-GSE蛋白,并验证了其安全性,为后续猪链球菌病亚单位疫苗的研制奠定了基础。 展开更多
关键词 猪链球菌 树突状细胞靶向肽 抗原表位 亚单位疫苗 细胞毒性
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