In the spring of 1999 the Ocean Drilling Pro-gram (ODP) Leg 184 Shipboard Party cored 17 holes at 6 deep water sites in the northern and southern parts of the South China Sea (SCS). Chinese scientists actively partici...In the spring of 1999 the Ocean Drilling Pro-gram (ODP) Leg 184 Shipboard Party cored 17 holes at 6 deep water sites in the northern and southern parts of the South China Sea (SCS). Chinese scientists actively partici-pated in the entire process of this first deep-sea drilling leg off China, from proposal to post-cruise studies. More than 30 categories of analyses have been conducted post-cruise in various Chinese laboratories on a large number of core sam-ples, and the total number of analyses exceeded 60 thousand. The major scientific achievements of the Leg 184 studies are briefly reported in three successive papers, with the first one presented here dealing with deep-sea stratigraphy and evolu-tion of climate cycles. This ODP leg has established the best deep-sea stratigraphic sequences in the Western Pacific: the 23-Ma isotope sequence from the Dong-Sha area is unique worldwide because of its continuity; the last 5-Ma sequence from the Nansha area represents one of the best 4 ODP sites worldwide with the highest time-resolution for that time in-terval, and the sequences of physical properties enable a de-cadal-scale time resolution. All these together have provided for the first time high-quality marine records for paleoenvi-ronmental studies in the Asian-Pacific region. This new set of stratigraphic records has revealed changes in climate cyclic-ity over the last 20 Ma with the fluctuating power of the 100 ka, 400 ka, 2000 ka eccentricity cycles, indicating the evolv-ing response of the climate system to orbital forcing along with the growth of the Antarctic and Northern Hemisphere ice sheets.展开更多
As the third summary report of ODP Leg 184 to the South China Sea (SCS), this paper discusses the evolution of the East Asian monsoon and the SCS basin. A multi-proxy approach, involving geochemistry, micropaleontolog...As the third summary report of ODP Leg 184 to the South China Sea (SCS), this paper discusses the evolution of the East Asian monsoon and the SCS basin. A multi-proxy approach, involving geochemistry, micropaleontology, pollen and other analyses, was adopted for reconstructing the evolutionary history of the East Asian monsoon, which was characterized by a series of paleo-climate events especially at 8, 3.2, 2.2 and 0.4 Ma. The new record indicates similar stages in the development of the East and South Asian monsoons, with an enhanced winter monsoon over East Asia being the major difference. The rich spectrums of monsoon variability from the southern SCS also reveal other characteristic features of the low latitude ocean. Evidence for the evolution of the SCS includes the hemipelagic Oligocene sediments, implying the existence of deep water environments during the early seafloor spreading stage of the SCS basin. The four major unconformities and some remarkable diagenetic features in upper Oligocene deposits indicate the strongest tectonic events in the region. From a careful comparison of lithologies and sedimentation rates, we conclude that the prominent differences in sedimentary environments between the southern and northern SCS were established only by ～3 Ma.展开更多
The western Noah Pacific anomalous anticyclone （WNPAC） is an important atmospheric circulation system that conveys El Nifio impact on East Asian climate. In this review paper, various theories on the formation and m...The western Noah Pacific anomalous anticyclone （WNPAC） is an important atmospheric circulation system that conveys El Nifio impact on East Asian climate. In this review paper, various theories on the formation and maintenance of the WNPAC, including warm pool atmosphere-ocean interaction, Indian Ocean capacitor, a combination mode that emphasizes nonlinear interaction between ENSO and annual cycle, moist enthalpy advecfion/Rossby wave modulation, and central Pacific SST forcing, are discussed. It is concluded that local atmosphere-ocean interaction and moist enthalpy advection/Rossby wave modulation mechanisms are essential for the initial development and maintenance of the WNPAC during El Nifio mature winter and subsequent spring. The Indian Ocean capacitor mechanism does not contribute to the earlier development but helps maintain the WNPAC in El Nifio decaying summer. The cold SST anomaly in the western North Pacific, although damped in the summer, also plays a role. An inter- basin atmosphere-ocean interaction across the Indo-Pacific warm pool emerges as a new mechanism in summer. In addition, the central Pacific cold SST anomaly may induce the WNPAC during rapid El Nifio decaying/La Nina developing or La Nifia persisting summer. The near-annual periods predicted by the combination mode theory are hardly detected from observations and thus do not contribute to the formation of the WNPAC. The tropical Atlantic may have a capacitor effect similar to the tropical Indian Ocean.展开更多
Using meteorological observations, proxies of precipitation and temperature, and climate simulation outputs, we synthetically analyzed the regularities of decadal-centennial-scale changes in the summer thermal contras...Using meteorological observations, proxies of precipitation and temperature, and climate simulation outputs, we synthetically analyzed the regularities of decadal-centennial-scale changes in the summer thermal contrast between land and ocean and summer precipitation over the East Asian monsoon region during the past millennium; compared the basic characteristics of the East Asian summer monsoon (EASM) circulation and precipitation in the present day, the Little Ice Age (LIA) and the Medieval Warm Period (MWP); and explored their links with solar irradiance and global climate change. The results indicate that over the last 150 years, the EASM circulation and precipitation, indicated by the temperature contrast between the East Asian mainland and adjacent oceans, had a significant decadal perturbation and have been weaker during the period of rapid global warming over the past 50 years. On the centennial time scale, the EASM in the MWP was strongest over the past 1000 years. Over the past 1000 years, the EASM was weakest in 1450-1570. When the EASM circulation was weaker, the monsoon rain belt over eastern China was generally located more southward, with there being less precipitation in North China and more precipitation in the Yangtze River valley; therefore, there was an anomalous pattern of southern flood/northern drought. From the 1900s to 1920s, precipitation had a pat- tern opposite to that of the southern flood/northern drought, with there being less precipitation in the Yangtze River valley and more precipitation in North China. Compared with the case for the MWP, there was a longer-time-scale southern flood/northern drought phenomenon in 1400-1600. Moreover, the EASM circulation and precipitation did not synchronously vary with the trend of global temperature. During the last 150 years, although the annual mean surface temperature around the world and in China has increased, the EASM circulation and precipitation did not have strengthening or weakening trends. Over the past 1000 years, the weakest EASM oc展开更多
To compare differences among the Medieval Warm Period (MWP), Little Ice Age (LIA), and 20th century global warming (20CW), six sets of transient and equilibrium simulations were generated using the climate system mode...To compare differences among the Medieval Warm Period (MWP), Little Ice Age (LIA), and 20th century global warming (20CW), six sets of transient and equilibrium simulations were generated using the climate system model FGOALS_gl. This model was developed by the State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics, Institute of Atmospheric Physics, Chinese Academy of Sciences. The results indicate that MWP warming is evident on a global scale, except for at mid-latitudes of the North Pacific. However, the magnitude of the warming is weaker than that in the 20th century. The warming in the high latitudes of the Northern Hemisphere is stronger than that in the Southern Hemisphere. The LIA cooling is also evident on a global scale, with a strong cooling over the high Eurasian continent, while the cooling center is over the Arctic domain. Both the MWP and the 20CW experiments exhibit the strongest warming anomalies in the middle troposphere around 200-300 hPa, but the cooling center of the LIA experiment is seen in the polar surface of the Northern Hemisphere. A comparison of model simulation against the reconstruction indicates that model's performance in simulating the surface air temperature changes during the warm periods is better than that during the cold periods. The consistencies between model and reconstruction in lower latitudes are better than those in high latitudes. Comparison of the inter-annual variability mode of East Asian summer monsoon (EASM) rainfall during the MWP, LIA and 20CW reveals a similar rainfall anomalies pattern. However, the time spectra of the principal component during the three typical periods of the last millennium are different, and the quasi-biannual oscillation is more evident during the two warm periods. At a centennial time scale, the external mode of the EASM variability driven by the changes of effective solar radiation is determined by the changes of large scale land-sea thermal contrast. The rainfall anomalies over the east of 1展开更多
Previous studies have documented a weakening tendency of the East Asian summer monsoon (EASM) since the end of the 1970s. In this study, we report that the EASM has been recovering since the early 1990s, although its ...Previous studies have documented a weakening tendency of the East Asian summer monsoon (EASM) since the end of the 1970s. In this study, we report that the EASM has been recovering since the early 1990s, although its strength is still less than in previous decades (averaged over the period 1965-1980). Following the recovery of the EASM, there has been a tendency in the last decade toward northward-moving rainbands and excessive rainfall in the Huaihe River valley (110°-120°E, 30°-35°N). There is evidence suggesting that the strengthening EASM since the early 1990s is linked to interdecadal change of land-sea thermal contrast.展开更多
No effective drug treatments are available for coronavirus disease 2019(COVID-19).Host-directed therapies targeting the underlying aberrant immune responses leading to pulmonary tissue damage,death,or long-term functi...No effective drug treatments are available for coronavirus disease 2019(COVID-19).Host-directed therapies targeting the underlying aberrant immune responses leading to pulmonary tissue damage,death,or long-term functional disability in survivors require clinical evaluation.We performed a parallel assigned controlled,non-randomized,phase 1 clinical trial to evaluate the safety of human umbilical cord-derived mesenchymal stem cells(UC-MSCs)infusions in the treatment of patients with moderate and severe COVID-19 pulmonary disease.The study enrolled 18 hospitalized patients with COVID-19(n=9 for each group).The treatment group received three cycles of intravenous infusion of UC-MSCs(3×107 cells per infusion)on days 0,3,and 6.Both groups received standard COVID-treatment regimens.Adverse events,duration of clinical symptoms,laboratory parameters,length of hospitalization,serial chest computed tomography(CT)images,the PaO2/FiO2 ratio,dynamics of cytokines,and IgG and IgM anti-SARS-CoV-2 antibodies were analyzed.No serious UC-MSCs infusion-associated adverse events were observed.Two patients receiving UC-MSCs developed transient facial flushing and fever,and one patient developed transient hypoxia at 12 h post UC-MSCs transfusion.Mechanical ventilation was required in one patient in the treatment group compared with four in the control group.All patients recovered and were discharged.Our data show that intravenous UC-MSCs infusion in patients with moderate and severe COVID-19 is safe and well tolerated.Phase 2/3 randomized,controlled,double-blinded trials with long-term follow-up are needed to evaluate the therapeutic use of UC-MSCs to reduce deaths and improve long-term treatment outcomes in patients with serious COVID-19.展开更多
Precipitation-related extremes are among the most impact-relevant consequences of a warmer climate,particularly for China,a region vulnerable to global warming and with a large population.Understanding the impacts and...Precipitation-related extremes are among the most impact-relevant consequences of a warmer climate,particularly for China,a region vulnerable to global warming and with a large population.Understanding the impacts and risks induced by future extreme precipitation changes is critical for mitigation and adaptation planning.Here,extreme precipitation changes under different levels of global warming and their associated impacts on populations in China are investigated using multimodel climate projections from the Coupled Model Intercomparison Project Phase 5 and population projections under Shared Socioeconomic Pathways.Heavy precipitation would intensify with warming across China at a rate of 6.52%(5.22%-8.57%)per degree of global warming.The longest dry spell length would increase(decrease)south(north)of-34°N.The low warming target of the Paris Agreement could substantially reduce the extreme precipitation related impacts compared to higher warming levels.For the area weighted average changes,the intensification in wet extremes could be reduced by 3.22%,9.42%and 16.70%over China,and the lengthening of dry spells could be reduced by 0.72%,4.75%and 5.31%in southeastern China,respectively,if global warming is limited to 1.5℃as compared to 2,3 and 4℃The Southeastern China is the hotspot of enhanced impacts due to the dense population.The impacts on populations induced by extreme precipitation changes are dominated by climate change,while future population redistribution plays a minor role.展开更多
Flexible tactile sensors have broad applications in human physiological monitoring,robotic operation and human-machine interaction.However,the research of wearable and flexible tactile sensors with high sensitivity,wi...Flexible tactile sensors have broad applications in human physiological monitoring,robotic operation and human-machine interaction.However,the research of wearable and flexible tactile sensors with high sensitivity,wide sensing range and ability to detect three-dimensional(3D)force is still very challenging.Herein,a flexible tactile electronic skin sensor based on carbon nanotubes(CNTs)/polydimethylsiloxane(PDMS)nanocomposites is presented for 3D contact force detection.The 3D forces were acquired from combination of four specially designed cells in a sensing element.Contributed from the double-sided rough porous structure and specific surface morphology of nanocomposites,the piezoresistive sensor possesses high sensitivity of 12.1 kPa?1 within the range of 600 Pa and 0.68 kPa?1 in the regime exceeding 1 kPa for normal pressure,as well as 59.9 N?1 in the scope of<0.05 N and>2.3 N?1 in the region of<0.6 N for tangential force with ultra-low response time of 3.1 ms.In addition,multi-functional detection in human body monitoring was employed with single sensing cell and the sensor array was integrated into a robotic arm for objects grasping control,indicating the capacities in intelligent robot applications.展开更多
A new coupled climate system model(CSM) has been developed at the Chinese Academy of Meteorological Sciences(CAMS) by employing several state-of-the-art component models. The coupled CAMS-CSM consists of the modified ...A new coupled climate system model(CSM) has been developed at the Chinese Academy of Meteorological Sciences(CAMS) by employing several state-of-the-art component models. The coupled CAMS-CSM consists of the modified atmospheric model [ECmwf-HAMburg(ECHAM5)], ocean model [Modular Ocean Model(MOM4)], sea ice model [Sea Ice Simulator(SIS)], and land surface model [Common Land Model(CoLM)]. A detailed model description is presented and both the pre-industrial and "historical" simulations are preliminarily evaluated in this study.The model can reproduce the climatological mean states and seasonal cycles of the major climate system quantities,including the sea surface temperature, precipitation, sea ice extent, and the equatorial thermocline. The major climate variability modes are also reasonably captured by the CAMS-CSM, such as the Madden–Julian Oscillation(MJO), El Ni?o–Southern Oscillation(ENSO), East Asian Summer Monsoon(EASM), and Pacific Decadal Oscillation(PDO).The model shows a promising ability to simulate the EASM variability and the ENSO–EASM relationship. Some biases still exist, such as the false double-intertropical convergence zone(ITCZ) in the annual mean precipitation field,the overestimated ENSO amplitude, and the weakened Bjerknes feedback associated with ENSO; and thus the CAMS-CSM needs further improvements.展开更多
Variations in global atmospheric oscillations during the last millennium are simulated using the climate system model FGOALS_gl. The model was driven by reconstructions of both natural forcing (solar variability and v...Variations in global atmospheric oscillations during the last millennium are simulated using the climate system model FGOALS_gl. The model was driven by reconstructions of both natural forcing (solar variability and volcanic aerosol) and anthropogenic forcing (greenhouse gases and sulfate aerosol). The model results are compared against proxy reconstruction data. The reconstructed North Atlantic Oscillation (NAO) was out of phase with the Pacific Decadal Oscillation (PDO) in the last millennium. During the Medieval Warm Period (MWP), the NAO was strong while the PDO was weak. During the Little Ice Age (LIA), the NAO was weak while the PDO was strong. A La Ni a-like state prevailed in the MWP, while an El Ni o-like state dominated in the LIA. This phenomenon is particularly obvious in the 15th, 17th and 19th centuries. Analysis of the model output indicates that the NAO was generally positive during 1000-1400 AD and negative during 1650-1900 AD. There is a discrepancy between the sim- ulation and reconstruction during 1400-1650 AD. The simulated PDO generally varies in parallel with the reconstruction, which has a negative phase during the MWP and a positive phase during the LIA. The correlation coefficient between the reconstruction and simulation is 0.61, and the correlation is statistically significant at the 1% level. Neither the La Ni a-like state of the MWP nor the El Ni o-like state of the LIA is reproduced in the model. Both the reconstructed and the simulated Antarctic Oscillations had a negative phase in the early period of the last millennium and a positive phase in the late period of the last millennium. The Asian-Pacific Oscillation was generally strong during the WMP and weak during the LIA, and the correlation coefficient between the simulation and reconstruction is 0.50 for the period 1000 -1985 AD. The analysis suggests that the specified external forcings significantly affected the evolution of atmospheric oscillation during the last millennium.展开更多
Associated with global warming, climate extremes such as extreme temperature will significantly increase. Understanding how climate change will impact the airflights is important to the planning of future flight opera...Associated with global warming, climate extremes such as extreme temperature will significantly increase. Understanding how climate change will impact the airflights is important to the planning of future flight operations. In this study, the impacts of 1.5 and 2 degree's global warming on the aircraft takeoff performance in China are investigated using a unique climate projection data from an international collaboration project named HAPPI. It is found that the mean summer daily maximum temperature, which is a major factor that affects the flight through changing the aircraft's takeoff weight, will increase significantly with magnitude less than 1.5℃ over most parts of China except for the Tibetan Plateau. The half a degree additional global warming will lead to higher extreme temperature in the arid and semi-arid western China, the Tibetan Plateau and the northeastern China, while the change in eastern China is weak. Five airports including Beijing, Shanghai, Kunming, Lasa and Urumqi will see ～1.0°-2.0℃(1.4°-3.0℃) higher daily maximum temperature under 1.5℃(2.0℃) scenario. The half-degree additional warming will lead to a shift toward higher extreme temperature in these five sites. For both1.5° and 2.0℃ scenarios, the number of weight-restriction days will increase significantly at 3 airports including Beijing, Shanghai, and Lasa. Urumqi will witness an increase of weight-restriction days only in 2.0℃ future.展开更多
The Tibetan Plateau(TP),as the world’s highest plateau,has almost all the key elements of the entire Earth system,including interconnected lithosphere,atmosphere,cryosphere,biosphere and anthroposphere[1-3].This comp...The Tibetan Plateau(TP),as the world’s highest plateau,has almost all the key elements of the entire Earth system,including interconnected lithosphere,atmosphere,cryosphere,biosphere and anthroposphere[1-3].This completeness makes the TP an ideal natural laboratory for studying multispheric interactions within the Earth system,and for cultivating key breakthroughs in geoscience of the 21st century[2,3].展开更多
The 2 ℃ warming target has been used widely in global and regional climate change research. Previous studies have shown large uncertainties in the time when surface air temperature （SAT） change over China will reac...The 2 ℃ warming target has been used widely in global and regional climate change research. Previous studies have shown large uncertainties in the time when surface air temperature （SAT） change over China will reach 2℃ rela- tive to the pre-industrial era. To understand the uncertainties, we analyzed the projected SAT in the twenty-first century using 40 state-of-the-art climate models under two Repre- sentative Concentration Pathways （RCP4.5 and RCPS.5） from the Coupled Model Intercomparison Project Phase 5. The 2℃ threshold-crossing time （TCT） of SAT averaged across China was around 2033 and 2029 for RCP4.5 and RCP8.5, respectively. Considering a 4-1o- range of inter- model SAT change, the upper and lower bounds of the 2 ℃ TCT could differ by about 25 years or even more. Uncer- tainty in the projected SAT and the warming rate around the TCT are the two main factors responsible for the TCT uncertainty. The former is determined by the climate sensi- tivity represented by the global mean surface temperature response. About 45 % of the intermodel variance of the projected 2 ~C TCT for averaged SAT over China can be explained by climate sensitivity across the models, which is contributed mainly by central and southern China. In a cli- mate more sensitive to CO2 forcing, stronger greenhouse effect, less stratus cloud over the East Asian monsoon region, and less snow cover on the Tibetan Plateau result in increased downward longwave radiation, increased shortwave radia- tion, and decreased shortwave radiation reflected by the surface, respectively, all of which may advance the TCT.展开更多
The Earth–Climate System Model(ECSM)is an important platform for multi-disciplinary and multi-sphere integration research,and its development is at the frontier of international geosciences,especially in the field of...The Earth–Climate System Model(ECSM)is an important platform for multi-disciplinary and multi-sphere integration research,and its development is at the frontier of international geosciences,especially in the field of global change.The research and development(R&D)of ECSM in China began in the 1980 s and have achieved great progress.In China,ECSMs are now mainly developed at the Chinese Academy of Sciences,ministries,and universities.Following a brief review of the development history of Chinese ECSMs,this paper summarized the technical characteristics of nine Chinese ECSMs participating in the Coupled Model Intercomparison Project Phase 6 and preliminarily assessed the basic performances of four Chinese models in simulating the global climate and the climate in East Asia.The projected changes of global precipitation and surface air temperature and the associated relationship with the equilibrium climate sensitivity under four shared socioeconomic path scenarios were also discussed.Finally,combined with the international situation,from the perspective of further improvement,eight directions were proposed for the future development of Chinese ECSMs.展开更多
Objective: Preablative stimulated thyroglobulin (ps-Tg) has the potential to be used in identifying distant metastatic differentiated thyroid carcinoma (DM-DTC), but its single level can be affected by remnant thyroid...Objective: Preablative stimulated thyroglobulin (ps-Tg) has the potential to be used in identifying distant metastatic differentiated thyroid carcinoma (DM-DTC), but its single level can be affected by remnant thyroid tissue and thyrotropin (TSH). The objective of this retrospective study was to evaluate the value of serial ps-Tg measurements in identifying DM-DTC specifically. Methods: A total of 317 DTC patients with serial measurements of ps-Tg, TSH and anti-Tg antibody were divided into M1 (n=72) and M0 (n=245) according to the presence of distant metastasis (DM) or not. The initial psTg measurement, with a corresponding TSH exceeding 30 mu IU/mL, was marked as Tg1, and ps-Tg measured right before radioactive iodine (RAI) therapy was defined as Tg2, with a median interval of 8 days. Delta Tg denotes Tg2-Tg1, and Delta TSH denotes TSH2-TSH1. Tg1, Tg2, Delta Tg, and Delta Tg/Delta TSH were tested for efficacy in identifying DM-DTC using receiver operating characteristic (ROC) curve analysis, and further compared with chest computed tomography (CT) and posttreatment whole-body RAI scan (RxWBS). Results: Compared with single ps-Tg measurement (Tg1 or Tg2), both Delta Tg and Delta Tg/Delta TSH were more narrowly distributed around zero in the M0 group, which made their distribution in the M1 group more distinguished in a relatively dispersed way. Delta Tg/Delta TSH manifested a higher accuracy (88.64%) and specificity (90.20%) in identifying DM-DTC than Tg1 or Tg2 measurements, with a much higher specificity than chest CT (90.20% vs. 66.00%) and a much higher sensitivity than RxWBS (83.33% vs. 61.11%). Conclusions: Serial ps-Tg measurements even over as short an interval as 8 days hold incremental value in identifying DM-DTC. Delta Tg/Delta TSH is a specific early biochemical marker for DM-DTC.展开更多
The performance of Version 2 of the Flexible Global Ocean-Atmosphere-Land System model （FGOALS-s2） in simulat ing global monsoon precipitation （GMP） was evaluated. Compared with FGOALS-sl, higher skill in simulati...The performance of Version 2 of the Flexible Global Ocean-Atmosphere-Land System model （FGOALS-s2） in simulat ing global monsoon precipitation （GMP） was evaluated. Compared with FGOALS-sl, higher skill in simulating the annual modes of climatological tropical precipitation and interannual variations of GMP are seen in FGOALS-s2. The simulated domains of the northwestern Pacific monsoon （NWPM） and North American monsoon are smaller than in FGOALS-s 1. The main deficiency of FGOALS-s2 is that the NWPM has a weaker monsoon mode and stronger negatiw,＇ pattern in spring-fall asymmetric mode. The smaller NWPM domain in FGOALS-s2 is due to its simulated colder SST over the western Pacific warm pool. The relationship between ENSO and GMP is simulated reasonably by FGOALS-s2. However, the simulated precipitation anomaly over the South African monsoon region-South Indian Ocean during La Nina years is opposite to the observation. This results mainly from weaker warm SST anomaly over the maritime continent during La Nifia years, leading to stronger upper-troposphere （lower-troposphere） divergence （convergence） over the Indian Ocean, and artificial vertical as cent （descent） over the Southwest Indian Ocean （South African monsoon region）, inducing local excessive （deficient） rainfall. Comparison between the historical and pre-industrial simulations indicated that global land monsoon precipitation changes from 1901 to the 1970s were caused by internal variation of climate system. External forcing may have contributed to the increasing trend of the Australian monsoon since the 1980s. Finally, it shows that global warming could enhance GMR especially over the northern hemispheric ocean monsoon and southern hemispheric land monsoon.展开更多
The long-term integration with the Global Ocean-Atmosphere-Land System model of the State Key Laboratory of Atmospheric Sciences and Geophysical Fluid Dynamics (LASG), Institute of Atmospheric Physics(IAP), Chinese Ac...The long-term integration with the Global Ocean-Atmosphere-Land System model of the State Key Laboratory of Atmospheric Sciences and Geophysical Fluid Dynamics (LASG), Institute of Atmospheric Physics(IAP), Chinese Academy of Sciences has been used in the investigations on the relationship between the thermohaline circulation and climate variability. The results show that the strength of the North Atlantic Thermohaline circulation (THC) is negatively correlated with the North Atlantic Oscillation (NAO). Based on this kind of relationship, and also the instrument-measured climate record such as air pressure and sea surface temperature, the activity of the thermohaline circulation during the 20th century has been evaluated. The inferred variations of the strength of the THC is that, during two multi-decadal periods of 1867-1903 and 1934-1972, the THC is estimated to have been running stronger, whereas during the two periods of 1904-1933 and 1973-1994, it appears to have been weaker.展开更多
The complete diallel cross design was employed to estimate the genetic parameters of the growth of Japanese flounder （Paralichthys olivaceus）. A total of 60 full-sib families were cultivated and two growth-related t...The complete diallel cross design was employed to estimate the genetic parameters of the growth of Japanese flounder （Paralichthys olivaceus）. A total of 60 full-sib families were cultivated and two growth-related traits, body weight （BW） and body length （BL）, were examined at average 2, 3 and 8 months of age respectively, with 1 800 individuals measured in each age group （30 per family）. Based on the additive-dominance-maternal-effect genetic analysis model, the restricted maximum likelihood approach was used to estimate various （co）variance components. The results showed that narrow-sense heritability estimates of BW and BL were respectively： 0.29 ± 0.01 and 0.22 ± 0.02 at 2 months of age, 0.32 ± 0.02 and 0.30 ± 0.04 at 3 months of age, 0.48 ± 0.04 and 0.40 ± 0.05 at 8 months of age; broad-sense heritability estimates were respectively： 0.44 ± 0.02 and 0.54 ± 0.04 at 2 months of age, 0.35 ± 0.01 and 0.36 ± 0.03 at 3 months of age, 0.49 ± 0.03 and 0.45 ± 0.04. All heritabilities were statistically significant （P 0.05）. Additive genetic correlations between BW and BL at 2, 3 and 8 months of age were consistently positive and highly significant （P 0.01）： 0.93 ± 0.02, 0.95 ± 0.03 and 0.92 ± 0.03 respectively. Maternal effect was significant （P 0.05） only at 2 months of age, and was not detected at 3 and 8 months of age. According to the heritability estimates, the mass selection strategy should be efficient for the breeding of Japanese flounder.展开更多
The Asian subtropical westerly jet(AWJ) exerts crucial influences on Eurasian continent weather and climate. This paper analyzes the advantages and limitations of CRA-40, which is China's first generation 40-yr(1...The Asian subtropical westerly jet(AWJ) exerts crucial influences on Eurasian continent weather and climate. This paper analyzes the advantages and limitations of CRA-40, which is China's first generation 40-yr(1979–2018) global atmosphere and land reanalysis product, in describing the characteristics of AWJ, compared with the ECMWF Reanalysis version 5(ERA5) and NCEP Climate Forecast System Reanalysis(CFSR). The results show a close agreement across the three reanalyses on the whole.(1) In terms of climatology, overall differences of 200-h Pa zonal wind across the three reanalyses are within ± 0.5 m s^(-1)(i.e., ± 2%). Large differences with maxima of ± 2 m s^(-1)(±5%) appear over the Iranian Plateau and south of the Tibetan Plateau in the mid–upper troposphere in winter.(2) For seasonal cycle, the position and intensity of the AWJ centers in the three reanalyses are highly consistent, with correlation coefficient over 0.98. But there are some discrepancies in the zonal shift of the western AWJ center during the transition season.(3) On the interannual timescale, intensity of all AWJ centers varies consistently among the three reanalyses, while larger differences appear in their meridional displacement, especially in the eastern AWJ center.(4)For long-term variations, the three reanalyses all present a significant northward movement of the westerly jet axis in winter, and a southward displacement over central Asia(40°–80°E) and a northward migration over East Asia(80°–110°E) in summer. Thus, this study has provided confidence that CRA-40 has comparable performance with ERA5 and CFSR in depicting the characteristics of AWJ.展开更多
基金supported by the National Natural Science Foundation of China(Grant No.49999560)the National Key Basic Research Special Fund(Grant G2000078500).
文摘In the spring of 1999 the Ocean Drilling Pro-gram (ODP) Leg 184 Shipboard Party cored 17 holes at 6 deep water sites in the northern and southern parts of the South China Sea (SCS). Chinese scientists actively partici-pated in the entire process of this first deep-sea drilling leg off China, from proposal to post-cruise studies. More than 30 categories of analyses have been conducted post-cruise in various Chinese laboratories on a large number of core sam-ples, and the total number of analyses exceeded 60 thousand. The major scientific achievements of the Leg 184 studies are briefly reported in three successive papers, with the first one presented here dealing with deep-sea stratigraphy and evolu-tion of climate cycles. This ODP leg has established the best deep-sea stratigraphic sequences in the Western Pacific: the 23-Ma isotope sequence from the Dong-Sha area is unique worldwide because of its continuity; the last 5-Ma sequence from the Nansha area represents one of the best 4 ODP sites worldwide with the highest time-resolution for that time in-terval, and the sequences of physical properties enable a de-cadal-scale time resolution. All these together have provided for the first time high-quality marine records for paleoenvi-ronmental studies in the Asian-Pacific region. This new set of stratigraphic records has revealed changes in climate cyclic-ity over the last 20 Ma with the fluctuating power of the 100 ka, 400 ka, 2000 ka eccentricity cycles, indicating the evolv-ing response of the climate system to orbital forcing along with the growth of the Antarctic and Northern Hemisphere ice sheets.
基金supported by the National Natural Science Foundation of China(Grant No.4999560)the National Key Basic Research Special Foundation(Grant No.G2000078500).
文摘As the third summary report of ODP Leg 184 to the South China Sea (SCS), this paper discusses the evolution of the East Asian monsoon and the SCS basin. A multi-proxy approach, involving geochemistry, micropaleontology, pollen and other analyses, was adopted for reconstructing the evolutionary history of the East Asian monsoon, which was characterized by a series of paleo-climate events especially at 8, 3.2, 2.2 and 0.4 Ma. The new record indicates similar stages in the development of the East and South Asian monsoons, with an enhanced winter monsoon over East Asia being the major difference. The rich spectrums of monsoon variability from the southern SCS also reveal other characteristic features of the low latitude ocean. Evidence for the evolution of the SCS includes the hemipelagic Oligocene sediments, implying the existence of deep water environments during the early seafloor spreading stage of the SCS basin. The four major unconformities and some remarkable diagenetic features in upper Oligocene deposits indicate the strongest tectonic events in the region. From a careful comparison of lithologies and sedimentation rates, we conclude that the prominent differences in sedimentary environments between the southern and northern SCS were established only by ～3 Ma.
基金Supported by the National Key Research and Development Program(2017YFA0603802,2015CB453200)National Natural Science Foundation of China(41630423,41475084,41575043,41375095)+3 种基金United States National Science Foundation(AGS-1565653)Jiangsu Province Natural Science Foundation Key Project(BK20150062)Jiangsu Shuang-Chuang Team Fund(R2014SCT001)Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)
文摘The western Noah Pacific anomalous anticyclone （WNPAC） is an important atmospheric circulation system that conveys El Nifio impact on East Asian climate. In this review paper, various theories on the formation and maintenance of the WNPAC, including warm pool atmosphere-ocean interaction, Indian Ocean capacitor, a combination mode that emphasizes nonlinear interaction between ENSO and annual cycle, moist enthalpy advecfion/Rossby wave modulation, and central Pacific SST forcing, are discussed. It is concluded that local atmosphere-ocean interaction and moist enthalpy advection/Rossby wave modulation mechanisms are essential for the initial development and maintenance of the WNPAC during El Nifio mature winter and subsequent spring. The Indian Ocean capacitor mechanism does not contribute to the earlier development but helps maintain the WNPAC in El Nifio decaying summer. The cold SST anomaly in the western North Pacific, although damped in the summer, also plays a role. An inter- basin atmosphere-ocean interaction across the Indo-Pacific warm pool emerges as a new mechanism in summer. In addition, the central Pacific cold SST anomaly may induce the WNPAC during rapid El Nifio decaying/La Nina developing or La Nifia persisting summer. The near-annual periods predicted by the combination mode theory are hardly detected from observations and thus do not contribute to the formation of the WNPAC. The tropical Atlantic may have a capacitor effect similar to the tropical Indian Ocean.
基金the National Natural Science Foundation of China (40890053 and 40890052)the National Basic Research Program of China (2007CB815901)the Special Project of Basic Science and Technology (2011FY120300)
文摘Using meteorological observations, proxies of precipitation and temperature, and climate simulation outputs, we synthetically analyzed the regularities of decadal-centennial-scale changes in the summer thermal contrast between land and ocean and summer precipitation over the East Asian monsoon region during the past millennium; compared the basic characteristics of the East Asian summer monsoon (EASM) circulation and precipitation in the present day, the Little Ice Age (LIA) and the Medieval Warm Period (MWP); and explored their links with solar irradiance and global climate change. The results indicate that over the last 150 years, the EASM circulation and precipitation, indicated by the temperature contrast between the East Asian mainland and adjacent oceans, had a significant decadal perturbation and have been weaker during the period of rapid global warming over the past 50 years. On the centennial time scale, the EASM in the MWP was strongest over the past 1000 years. Over the past 1000 years, the EASM was weakest in 1450-1570. When the EASM circulation was weaker, the monsoon rain belt over eastern China was generally located more southward, with there being less precipitation in North China and more precipitation in the Yangtze River valley; therefore, there was an anomalous pattern of southern flood/northern drought. From the 1900s to 1920s, precipitation had a pat- tern opposite to that of the southern flood/northern drought, with there being less precipitation in the Yangtze River valley and more precipitation in North China. Compared with the case for the MWP, there was a longer-time-scale southern flood/northern drought phenomenon in 1400-1600. Moreover, the EASM circulation and precipitation did not synchronously vary with the trend of global temperature. During the last 150 years, although the annual mean surface temperature around the world and in China has increased, the EASM circulation and precipitation did not have strengthening or weakening trends. Over the past 1000 years, the weakest EASM oc
基金the National Natural Science Foundation of China (40890054)
文摘To compare differences among the Medieval Warm Period (MWP), Little Ice Age (LIA), and 20th century global warming (20CW), six sets of transient and equilibrium simulations were generated using the climate system model FGOALS_gl. This model was developed by the State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics, Institute of Atmospheric Physics, Chinese Academy of Sciences. The results indicate that MWP warming is evident on a global scale, except for at mid-latitudes of the North Pacific. However, the magnitude of the warming is weaker than that in the 20th century. The warming in the high latitudes of the Northern Hemisphere is stronger than that in the Southern Hemisphere. The LIA cooling is also evident on a global scale, with a strong cooling over the high Eurasian continent, while the cooling center is over the Arctic domain. Both the MWP and the 20CW experiments exhibit the strongest warming anomalies in the middle troposphere around 200-300 hPa, but the cooling center of the LIA experiment is seen in the polar surface of the Northern Hemisphere. A comparison of model simulation against the reconstruction indicates that model's performance in simulating the surface air temperature changes during the warm periods is better than that during the cold periods. The consistencies between model and reconstruction in lower latitudes are better than those in high latitudes. Comparison of the inter-annual variability mode of East Asian summer monsoon (EASM) rainfall during the MWP, LIA and 20CW reveals a similar rainfall anomalies pattern. However, the time spectra of the principal component during the three typical periods of the last millennium are different, and the quasi-biannual oscillation is more evident during the two warm periods. At a centennial time scale, the external mode of the EASM variability driven by the changes of effective solar radiation is determined by the changes of large scale land-sea thermal contrast. The rainfall anomalies over the east of 1
基金supported by the National Natural Science Foundation of China (40890054, 40805026 and 40975058)the National Basic Research Program of China (2011CB403406)+1 种基金the Development Program of Science and Technology in the Shanxi Science and Technology Department(20100311131)the Foundation of CUIT (KYTZ201012)
文摘Previous studies have documented a weakening tendency of the East Asian summer monsoon (EASM) since the end of the 1970s. In this study, we report that the EASM has been recovering since the early 1990s, although its strength is still less than in previous decades (averaged over the period 1965-1980). Following the recovery of the EASM, there has been a tendency in the last decade toward northward-moving rainbands and excessive rainfall in the Huaihe River valley (110°-120°E, 30°-35°N). There is evidence suggesting that the strengthening EASM since the early 1990s is linked to interdecadal change of land-sea thermal contrast.
基金supported by The National Key R&D Program of China(2020YFC0841900,2020YFC0844000)The Innovation Groups of the National Natural Science Foundation of China(81721002)+2 种基金The National Science and Technology Major Project(2017YFA0105703)The Military Emergency Research Project for COVID-19(BWS20J006)The Project for Innovation of Military Medicine of China(16CXZ045).
文摘No effective drug treatments are available for coronavirus disease 2019(COVID-19).Host-directed therapies targeting the underlying aberrant immune responses leading to pulmonary tissue damage,death,or long-term functional disability in survivors require clinical evaluation.We performed a parallel assigned controlled,non-randomized,phase 1 clinical trial to evaluate the safety of human umbilical cord-derived mesenchymal stem cells(UC-MSCs)infusions in the treatment of patients with moderate and severe COVID-19 pulmonary disease.The study enrolled 18 hospitalized patients with COVID-19(n=9 for each group).The treatment group received three cycles of intravenous infusion of UC-MSCs(3×107 cells per infusion)on days 0,3,and 6.Both groups received standard COVID-treatment regimens.Adverse events,duration of clinical symptoms,laboratory parameters,length of hospitalization,serial chest computed tomography(CT)images,the PaO2/FiO2 ratio,dynamics of cytokines,and IgG and IgM anti-SARS-CoV-2 antibodies were analyzed.No serious UC-MSCs infusion-associated adverse events were observed.Two patients receiving UC-MSCs developed transient facial flushing and fever,and one patient developed transient hypoxia at 12 h post UC-MSCs transfusion.Mechanical ventilation was required in one patient in the treatment group compared with four in the control group.All patients recovered and were discharged.Our data show that intravenous UC-MSCs infusion in patients with moderate and severe COVID-19 is safe and well tolerated.Phase 2/3 randomized,controlled,double-blinded trials with long-term follow-up are needed to evaluate the therapeutic use of UC-MSCs to reduce deaths and improve long-term treatment outcomes in patients with serious COVID-19.
基金jointly supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA20060102)the International Partnership Program of Chinese Academy of Sciences(134111KYSB20160031)+2 种基金the National Natural Science Foundation of China(41330423,41905064)China Postdoctoral Science Foundation(2018M641450)the support from the Jiangsu Collaborative Innovation Center for Climate Change.
文摘Precipitation-related extremes are among the most impact-relevant consequences of a warmer climate,particularly for China,a region vulnerable to global warming and with a large population.Understanding the impacts and risks induced by future extreme precipitation changes is critical for mitigation and adaptation planning.Here,extreme precipitation changes under different levels of global warming and their associated impacts on populations in China are investigated using multimodel climate projections from the Coupled Model Intercomparison Project Phase 5 and population projections under Shared Socioeconomic Pathways.Heavy precipitation would intensify with warming across China at a rate of 6.52%(5.22%-8.57%)per degree of global warming.The longest dry spell length would increase(decrease)south(north)of-34°N.The low warming target of the Paris Agreement could substantially reduce the extreme precipitation related impacts compared to higher warming levels.For the area weighted average changes,the intensification in wet extremes could be reduced by 3.22%,9.42%and 16.70%over China,and the lengthening of dry spells could be reduced by 0.72%,4.75%and 5.31%in southeastern China,respectively,if global warming is limited to 1.5℃as compared to 2,3 and 4℃The Southeastern China is the hotspot of enhanced impacts due to the dense population.The impacts on populations induced by extreme precipitation changes are dominated by climate change,while future population redistribution plays a minor role.
基金funding from National Natural Science Foundation of China(NSFC Nos.61774157,81771388,61874121,and 61874012)Beijing Natural Science Foundation(No.4182075)the Capital Science and Technology Conditions Platform Project(Project ID:Z181100009518014).
文摘Flexible tactile sensors have broad applications in human physiological monitoring,robotic operation and human-machine interaction.However,the research of wearable and flexible tactile sensors with high sensitivity,wide sensing range and ability to detect three-dimensional(3D)force is still very challenging.Herein,a flexible tactile electronic skin sensor based on carbon nanotubes(CNTs)/polydimethylsiloxane(PDMS)nanocomposites is presented for 3D contact force detection.The 3D forces were acquired from combination of four specially designed cells in a sensing element.Contributed from the double-sided rough porous structure and specific surface morphology of nanocomposites,the piezoresistive sensor possesses high sensitivity of 12.1 kPa?1 within the range of 600 Pa and 0.68 kPa?1 in the regime exceeding 1 kPa for normal pressure,as well as 59.9 N?1 in the scope of<0.05 N and>2.3 N?1 in the region of<0.6 N for tangential force with ultra-low response time of 3.1 ms.In addition,multi-functional detection in human body monitoring was employed with single sensing cell and the sensor array was integrated into a robotic arm for objects grasping control,indicating the capacities in intelligent robot applications.
基金Supported by the National Key Research and Development Program of China(2016YFE0102400)National Natural Science Foundation of China(91637210 and 91737306)Basic Research Fund of the Chinese Academy of Meteorological Sciences(2018Z007)
文摘A new coupled climate system model(CSM) has been developed at the Chinese Academy of Meteorological Sciences(CAMS) by employing several state-of-the-art component models. The coupled CAMS-CSM consists of the modified atmospheric model [ECmwf-HAMburg(ECHAM5)], ocean model [Modular Ocean Model(MOM4)], sea ice model [Sea Ice Simulator(SIS)], and land surface model [Common Land Model(CoLM)]. A detailed model description is presented and both the pre-industrial and "historical" simulations are preliminarily evaluated in this study.The model can reproduce the climatological mean states and seasonal cycles of the major climate system quantities,including the sea surface temperature, precipitation, sea ice extent, and the equatorial thermocline. The major climate variability modes are also reasonably captured by the CAMS-CSM, such as the Madden–Julian Oscillation(MJO), El Ni?o–Southern Oscillation(ENSO), East Asian Summer Monsoon(EASM), and Pacific Decadal Oscillation(PDO).The model shows a promising ability to simulate the EASM variability and the ENSO–EASM relationship. Some biases still exist, such as the false double-intertropical convergence zone(ITCZ) in the annual mean precipitation field,the overestimated ENSO amplitude, and the weakened Bjerknes feedback associated with ENSO; and thus the CAMS-CSM needs further improvements.
基金the National Natural Science Foundation of China (40890054)the National Key Technology R&D Program of China (2007BAC29B03)
文摘Variations in global atmospheric oscillations during the last millennium are simulated using the climate system model FGOALS_gl. The model was driven by reconstructions of both natural forcing (solar variability and volcanic aerosol) and anthropogenic forcing (greenhouse gases and sulfate aerosol). The model results are compared against proxy reconstruction data. The reconstructed North Atlantic Oscillation (NAO) was out of phase with the Pacific Decadal Oscillation (PDO) in the last millennium. During the Medieval Warm Period (MWP), the NAO was strong while the PDO was weak. During the Little Ice Age (LIA), the NAO was weak while the PDO was strong. A La Ni a-like state prevailed in the MWP, while an El Ni o-like state dominated in the LIA. This phenomenon is particularly obvious in the 15th, 17th and 19th centuries. Analysis of the model output indicates that the NAO was generally positive during 1000-1400 AD and negative during 1650-1900 AD. There is a discrepancy between the sim- ulation and reconstruction during 1400-1650 AD. The simulated PDO generally varies in parallel with the reconstruction, which has a negative phase during the MWP and a positive phase during the LIA. The correlation coefficient between the reconstruction and simulation is 0.61, and the correlation is statistically significant at the 1% level. Neither the La Ni a-like state of the MWP nor the El Ni o-like state of the LIA is reproduced in the model. Both the reconstructed and the simulated Antarctic Oscillations had a negative phase in the early period of the last millennium and a positive phase in the late period of the last millennium. The Asian-Pacific Oscillation was generally strong during the WMP and weak during the LIA, and the correlation coefficient between the simulation and reconstruction is 0.50 for the period 1000 -1985 AD. The analysis suggests that the specified external forcings significantly affected the evolution of atmospheric oscillation during the last millennium.
基金supported by the National Natural Science Foundation of China(41330423 and 41420104006)supported by the Applied Basic Research Programs of Science and Technology Department of Sichuan Province(2015JY0109)the Grant of Civil Aviation University of China(2016QD05X)
文摘Associated with global warming, climate extremes such as extreme temperature will significantly increase. Understanding how climate change will impact the airflights is important to the planning of future flight operations. In this study, the impacts of 1.5 and 2 degree's global warming on the aircraft takeoff performance in China are investigated using a unique climate projection data from an international collaboration project named HAPPI. It is found that the mean summer daily maximum temperature, which is a major factor that affects the flight through changing the aircraft's takeoff weight, will increase significantly with magnitude less than 1.5℃ over most parts of China except for the Tibetan Plateau. The half a degree additional global warming will lead to higher extreme temperature in the arid and semi-arid western China, the Tibetan Plateau and the northeastern China, while the change in eastern China is weak. Five airports including Beijing, Shanghai, Kunming, Lasa and Urumqi will see ～1.0°-2.0℃(1.4°-3.0℃) higher daily maximum temperature under 1.5℃(2.0℃) scenario. The half-degree additional warming will lead to a shift toward higher extreme temperature in these five sites. For both1.5° and 2.0℃ scenarios, the number of weight-restriction days will increase significantly at 3 airports including Beijing, Shanghai, and Lasa. Urumqi will witness an increase of weight-restriction days only in 2.0℃ future.
基金This work was supported by the National Natural Science Foundation of China(41988101).
文摘The Tibetan Plateau(TP),as the world’s highest plateau,has almost all the key elements of the entire Earth system,including interconnected lithosphere,atmosphere,cryosphere,biosphere and anthroposphere[1-3].This completeness makes the TP an ideal natural laboratory for studying multispheric interactions within the Earth system,and for cultivating key breakthroughs in geoscience of the 21st century[2,3].
基金supported jointly by the ‘‘Strategic Priority Research Program–Climate Change: Carbon Budget and Related Issues’’ of the Chinese Academy of Sciences (XDA05110300)the Research Fund for Commonwealth Trades (Meteorology) (GYHY201506012)+1 种基金the National Natural Science Foundation of China (41420104006)the China Postdoctoral Science Foundation (2015M581152)
文摘The 2 ℃ warming target has been used widely in global and regional climate change research. Previous studies have shown large uncertainties in the time when surface air temperature （SAT） change over China will reach 2℃ rela- tive to the pre-industrial era. To understand the uncertainties, we analyzed the projected SAT in the twenty-first century using 40 state-of-the-art climate models under two Repre- sentative Concentration Pathways （RCP4.5 and RCPS.5） from the Coupled Model Intercomparison Project Phase 5. The 2℃ threshold-crossing time （TCT） of SAT averaged across China was around 2033 and 2029 for RCP4.5 and RCP8.5, respectively. Considering a 4-1o- range of inter- model SAT change, the upper and lower bounds of the 2 ℃ TCT could differ by about 25 years or even more. Uncer- tainty in the projected SAT and the warming rate around the TCT are the two main factors responsible for the TCT uncertainty. The former is determined by the climate sensi- tivity represented by the global mean surface temperature response. About 45 % of the intermodel variance of the projected 2 ~C TCT for averaged SAT over China can be explained by climate sensitivity across the models, which is contributed mainly by central and southern China. In a cli- mate more sensitive to CO2 forcing, stronger greenhouse effect, less stratus cloud over the East Asian monsoon region, and less snow cover on the Tibetan Plateau result in increased downward longwave radiation, increased shortwave radia- tion, and decreased shortwave radiation reflected by the surface, respectively, all of which may advance the TCT.
基金Supported by the International Partnership Program of Chinese Academy of Sciences(134111KYSB20160031)National Natural Science Foundation of China(41875132).
文摘The Earth–Climate System Model(ECSM)is an important platform for multi-disciplinary and multi-sphere integration research,and its development is at the frontier of international geosciences,especially in the field of global change.The research and development(R&D)of ECSM in China began in the 1980 s and have achieved great progress.In China,ECSMs are now mainly developed at the Chinese Academy of Sciences,ministries,and universities.Following a brief review of the development history of Chinese ECSMs,this paper summarized the technical characteristics of nine Chinese ECSMs participating in the Coupled Model Intercomparison Project Phase 6 and preliminarily assessed the basic performances of four Chinese models in simulating the global climate and the climate in East Asia.The projected changes of global precipitation and surface air temperature and the associated relationship with the equilibrium climate sensitivity under four shared socioeconomic path scenarios were also discussed.Finally,combined with the international situation,from the perspective of further improvement,eight directions were proposed for the future development of Chinese ECSMs.
基金supported by the Ministry of Health Industry Special Scientific Research Projects of China (No. 201202012)the National Natural Science Foundation of China (No. 81571714)
文摘Objective: Preablative stimulated thyroglobulin (ps-Tg) has the potential to be used in identifying distant metastatic differentiated thyroid carcinoma (DM-DTC), but its single level can be affected by remnant thyroid tissue and thyrotropin (TSH). The objective of this retrospective study was to evaluate the value of serial ps-Tg measurements in identifying DM-DTC specifically. Methods: A total of 317 DTC patients with serial measurements of ps-Tg, TSH and anti-Tg antibody were divided into M1 (n=72) and M0 (n=245) according to the presence of distant metastasis (DM) or not. The initial psTg measurement, with a corresponding TSH exceeding 30 mu IU/mL, was marked as Tg1, and ps-Tg measured right before radioactive iodine (RAI) therapy was defined as Tg2, with a median interval of 8 days. Delta Tg denotes Tg2-Tg1, and Delta TSH denotes TSH2-TSH1. Tg1, Tg2, Delta Tg, and Delta Tg/Delta TSH were tested for efficacy in identifying DM-DTC using receiver operating characteristic (ROC) curve analysis, and further compared with chest computed tomography (CT) and posttreatment whole-body RAI scan (RxWBS). Results: Compared with single ps-Tg measurement (Tg1 or Tg2), both Delta Tg and Delta Tg/Delta TSH were more narrowly distributed around zero in the M0 group, which made their distribution in the M1 group more distinguished in a relatively dispersed way. Delta Tg/Delta TSH manifested a higher accuracy (88.64%) and specificity (90.20%) in identifying DM-DTC than Tg1 or Tg2 measurements, with a much higher specificity than chest CT (90.20% vs. 66.00%) and a much higher sensitivity than RxWBS (83.33% vs. 61.11%). Conclusions: Serial ps-Tg measurements even over as short an interval as 8 days hold incremental value in identifying DM-DTC. Delta Tg/Delta TSH is a specific early biochemical marker for DM-DTC.
基金supported by the"Strategic Priority Research Program-Climate Change:Carbon Budget and Related Issues"of the Chinese Academy of Sciences(Grant No.XDA05110301)the Program of Excellent State Key Laboratories(Grant No.41023002)the National HighTech Research and Development Plan of China(Grant No.2010AA012302)
文摘The performance of Version 2 of the Flexible Global Ocean-Atmosphere-Land System model （FGOALS-s2） in simulat ing global monsoon precipitation （GMP） was evaluated. Compared with FGOALS-sl, higher skill in simulating the annual modes of climatological tropical precipitation and interannual variations of GMP are seen in FGOALS-s2. The simulated domains of the northwestern Pacific monsoon （NWPM） and North American monsoon are smaller than in FGOALS-s 1. The main deficiency of FGOALS-s2 is that the NWPM has a weaker monsoon mode and stronger negatiw,＇ pattern in spring-fall asymmetric mode. The smaller NWPM domain in FGOALS-s2 is due to its simulated colder SST over the western Pacific warm pool. The relationship between ENSO and GMP is simulated reasonably by FGOALS-s2. However, the simulated precipitation anomaly over the South African monsoon region-South Indian Ocean during La Nina years is opposite to the observation. This results mainly from weaker warm SST anomaly over the maritime continent during La Nifia years, leading to stronger upper-troposphere （lower-troposphere） divergence （convergence） over the Indian Ocean, and artificial vertical as cent （descent） over the Southwest Indian Ocean （South African monsoon region）, inducing local excessive （deficient） rainfall. Comparison between the historical and pre-industrial simulations indicated that global land monsoon precipitation changes from 1901 to the 1970s were caused by internal variation of climate system. External forcing may have contributed to the increasing trend of the Australian monsoon since the 1980s. Finally, it shows that global warming could enhance GMR especially over the northern hemispheric ocean monsoon and southern hemispheric land monsoon.
文摘The long-term integration with the Global Ocean-Atmosphere-Land System model of the State Key Laboratory of Atmospheric Sciences and Geophysical Fluid Dynamics (LASG), Institute of Atmospheric Physics(IAP), Chinese Academy of Sciences has been used in the investigations on the relationship between the thermohaline circulation and climate variability. The results show that the strength of the North Atlantic Thermohaline circulation (THC) is negatively correlated with the North Atlantic Oscillation (NAO). Based on this kind of relationship, and also the instrument-measured climate record such as air pressure and sea surface temperature, the activity of the thermohaline circulation during the 20th century has been evaluated. The inferred variations of the strength of the THC is that, during two multi-decadal periods of 1867-1903 and 1934-1972, the THC is estimated to have been running stronger, whereas during the two periods of 1904-1933 and 1973-1994, it appears to have been weaker.
基金Special Fund for Agro-scientific Research in the Public Interest of China under contract No.200903046Research Foundation of Zhejiang Province,China under contract No.2009C12078+1 种基金National Sparking Plan Project of China under contract No.2010GA700010Taishan Scholar Project of Shandong Province,China
文摘The complete diallel cross design was employed to estimate the genetic parameters of the growth of Japanese flounder （Paralichthys olivaceus）. A total of 60 full-sib families were cultivated and two growth-related traits, body weight （BW） and body length （BL）, were examined at average 2, 3 and 8 months of age respectively, with 1 800 individuals measured in each age group （30 per family）. Based on the additive-dominance-maternal-effect genetic analysis model, the restricted maximum likelihood approach was used to estimate various （co）variance components. The results showed that narrow-sense heritability estimates of BW and BL were respectively： 0.29 ± 0.01 and 0.22 ± 0.02 at 2 months of age, 0.32 ± 0.02 and 0.30 ± 0.04 at 3 months of age, 0.48 ± 0.04 and 0.40 ± 0.05 at 8 months of age; broad-sense heritability estimates were respectively： 0.44 ± 0.02 and 0.54 ± 0.04 at 2 months of age, 0.35 ± 0.01 and 0.36 ± 0.03 at 3 months of age, 0.49 ± 0.03 and 0.45 ± 0.04. All heritabilities were statistically significant （P 0.05）. Additive genetic correlations between BW and BL at 2, 3 and 8 months of age were consistently positive and highly significant （P 0.01）： 0.93 ± 0.02, 0.95 ± 0.03 and 0.92 ± 0.03 respectively. Maternal effect was significant （P 0.05） only at 2 months of age, and was not detected at 3 and 8 months of age. According to the heritability estimates, the mass selection strategy should be efficient for the breeding of Japanese flounder.
基金Supported by the Program of International S&T Cooperation of Chinese Academy of Sciences (2018YFE0196000)National Natural Science Foundation of China (41675076)。
文摘The Asian subtropical westerly jet(AWJ) exerts crucial influences on Eurasian continent weather and climate. This paper analyzes the advantages and limitations of CRA-40, which is China's first generation 40-yr(1979–2018) global atmosphere and land reanalysis product, in describing the characteristics of AWJ, compared with the ECMWF Reanalysis version 5(ERA5) and NCEP Climate Forecast System Reanalysis(CFSR). The results show a close agreement across the three reanalyses on the whole.(1) In terms of climatology, overall differences of 200-h Pa zonal wind across the three reanalyses are within ± 0.5 m s^(-1)(i.e., ± 2%). Large differences with maxima of ± 2 m s^(-1)(±5%) appear over the Iranian Plateau and south of the Tibetan Plateau in the mid–upper troposphere in winter.(2) For seasonal cycle, the position and intensity of the AWJ centers in the three reanalyses are highly consistent, with correlation coefficient over 0.98. But there are some discrepancies in the zonal shift of the western AWJ center during the transition season.(3) On the interannual timescale, intensity of all AWJ centers varies consistently among the three reanalyses, while larger differences appear in their meridional displacement, especially in the eastern AWJ center.(4)For long-term variations, the three reanalyses all present a significant northward movement of the westerly jet axis in winter, and a southward displacement over central Asia(40°–80°E) and a northward migration over East Asia(80°–110°E) in summer. Thus, this study has provided confidence that CRA-40 has comparable performance with ERA5 and CFSR in depicting the characteristics of AWJ.
