Located in the eastern portion of the Xing'an-Mongolian Orogenic Belt (XMOB), the Xinkailing-Kele complex has previously been considered to be Precambrian metamorphic rocks, mainly according to its relatively high...Located in the eastern portion of the Xing'an-Mongolian Orogenic Belt (XMOB), the Xinkailing-Kele complex has previously been considered to be Precambrian metamorphic rocks, mainly according to its relatively high metamorphic grade. Our filed observation, however, revealed that the complex is composed mainly of metamorphic rocks (Kele complex), tectono-schists (“Xinkailing Group”),and granitoids (Xinkailing granitic complex). Dating on these rocks using advanced SHRIMP zircon U-Pb technique indicates that: (1) Biotite-plagioclase gneiss from the Kele complex has a protolith age of 337±7Ma (2σ) and a metamorphic age of 216±3Ma (2σ); (2) the tectono-schist of the “Xinkailing Group” gave a magmatic age of 292±6Ma (2σ), indicative of felsic volcanic protolith of the schist formed in Late Paleozoic time; and (3) the Menluhedingzi and Lengchuan granites of the Xinkailing granitic complex were emplaced at167±4 (20σ) and 164±4Ma (2σ), respectively. These results suggest that the Xinkailing-Kele complex is not Precambrian metamorphic rocks and the so-called Precambrian “Nenji-ang Block” does essentially not exist. In combination with regional geological data, we propose that the Kele metamorphic complex is likely related to a collisional tectonism that took place in Triassic lime, as indicted by its metamorphic age of 216±3Ma. The Xinkailing granitic complex was emplaced along the collisional zone during Mid-Jurassic time，likely in a post-orogenic or anorogenic setting.展开更多
The Xilin Gol Complex, consisting of deformed and metamorphosed rocks, was exposed as a large geological unit within the Central Asian Orogenic Belt, but its forming and subsequent deformed and metamorphic time has be...The Xilin Gol Complex, consisting of deformed and metamorphosed rocks, was exposed as a large geological unit within the Central Asian Orogenic Belt, but its forming and subsequent deformed and metamorphic time has been an issue of little consensus. Petrographic analyses and SHRIMP dating on biotite-plagioclase gneiss, one of the ma-jor rocks within the Xilin Gol Complex, in southeast Xilinhot City, Inner Mongolia, China, where the Xilin Gol Complex was identified and named, yield its lower limit age of 437 3 Ma (2s ) by its magmatic zircon SHRIMP U-Pb dating, and an upper limit age of 316 3Ma (2s ), which was constrained by SHRIMP dating of magmatic zircons from adjacent un-deformed garnet-bearing granite which intruded the Com-plex. The Complex was thus determined to be formed and subsequently deformed/metamorphosed from the late Ordovi-cian-early Silurian to the mid-Carboniferous. Consequently, it is not the Precambrian terrane as previously considered by most geologists. More or less, the major rock——biotite- plagioclase gneiss within the Complex is more likely to be Paleozoic fore-arc turbidite formation before metamorphism and intensive deformation, in which the detrital zircons gave sporadic Precambrian ages as old as up to 3.1 Ga. The source of the turbidite formation is multiple, which may be derived either from the North China Craton, or from the South- Mongolia Micro-continent, or probably came from a poten-tial and undiscovered in situ terranes aged 600—800 Ma or even up to ca 3.1 Ga near the Complex.展开更多
The antiviral activity in vitro and in vivo and the effect of the immune system of two fucoidan fractions with low molecular weight and different sulfate content from Laminaria japonica(LMW fucoidans) were investigate...The antiviral activity in vitro and in vivo and the effect of the immune system of two fucoidan fractions with low molecular weight and different sulfate content from Laminaria japonica(LMW fucoidans) were investigated in order to examine the possible mechanism. In vitro, I-type influenza virus, adenovirus and Parainfluenza virus I were used to infect Hep-2, Hela and MDCK cells, respectively. And 50% tissue culture infective dose was calculated to detect the antiviral activity of two LMW fucoidans. The results indicated that compared with the control group, 2 kinds of LMW fucoidans had remarkable antiviral activity in vitro in middle and high doses, while at low doses, the antiviral activity of 2 kinds of LMW fucoidans was not statistically different from that in the blank control group. And there was no statistically difference between two LMW fucoidans in antiviral activity. In vivo, LMW fucoidans could prolong the survival time of virus-infected mice, and could improve the lung index of virus-infected mice significantly, which have statistical differences with the control group significantly(p < 0.01). However, the survival time of the two LMW fucoidans was not statistically significant(p > 0.05). In this study, it was shown that both of two LMW fucoidans(LF1, LF2) could increase the thymus index, spleen index, phagocytic index, phagocytosis coefficient and half hemolysin value in middle and high doses, which suggested that LMW fucoidans could play an antiviral role by improving the quality of immune organs, improving immune cell phagocytosis and humoral immunity.展开更多
This study was carried out explore the mechanism underlying the inhibition of platelet activation by kelp fucoidans in deep venous thrombosis(DVT)mouse.In the control and sham mice,the walls of deep vein were regular ...This study was carried out explore the mechanism underlying the inhibition of platelet activation by kelp fucoidans in deep venous thrombosis(DVT)mouse.In the control and sham mice,the walls of deep vein were regular and smooth with intact intima,myometrium and adventitia.The blood vessel was wrapped with the tissue and there was no thrombosis in the lumen.In the DVT model,the wall was uneven with thicken intima,myometrium and adventitia.After treated with fucoidans LF1 and LF2,the thrombus was dissolved and the blood vessel was recanalized.Compared with the control group,the ROS content,ET-1 and VWF content and the expression of PKC-βand NF-κB in the model were significantly higher(P<0.05);these levels were significantly reduced following treatments with LF2 and LF1.Compared with H_(2)O_(2)treated-HUVECs,combined LF1 and LF2 treatment resulted in significant decrease in the expression of PKC-β,NF-κB,VWF and TM protein(P<0.05).It is clear that LF1 and LF2 reduces DVT-induced ET-1,VWF and TM expressions and production of ROS,thus inhibiting the activation of PKC-β/NF-κB signal pathway and the activation of coagulation system and ultimately reducing the formation of venous thrombus.展开更多
γ-LiAlO2 single crystal is a promising substrate for GaN heteroepitaxy. In this paper, we present the growth of large-sized LiAlO2 crystal by modified Czochralski method. The crystal quality was characterized by high...γ-LiAlO2 single crystal is a promising substrate for GaN heteroepitaxy. In this paper, we present the growth of large-sized LiAlO2 crystal by modified Czochralski method. The crystal quality was characterized by high-resolution X-ray diffraction and chemical etching. The results show that the as-grown crystal has perfect quality with the full width at half maximum （FWHM） of 17.7-22.6 arcsec and etch pits density of （0.3- 2.2）×10^4 cm^-2 throughout the crystal boule. The bottom of the crystal boule shows the best quality. The optical transmission spectra from UV to IR exhibits that the crystal is transparent from 0.2 to 5.5μm and becomes completely absorbing around 6.7μm wavelength, The optical absorption edge in near UV region is about 191 nm.展开更多
Real driving scenarios,due to occlusions and disturbances,provide disordered and noisy measurements,which makes the task of multi-object tracking quite challenging.Conventional approach is to find deterministic data a...Real driving scenarios,due to occlusions and disturbances,provide disordered and noisy measurements,which makes the task of multi-object tracking quite challenging.Conventional approach is to find deterministic data association;however,it has unstable performance in high clutter density.This paper proposes a novel probabilistic tracklet-enhanced multiple object tracker(PTMOT),which integrates Poisson multi-Bernoulli mixture(PMBM)filter with confidence of tracklets.The proposed method is able to realize efficient and robust probabilistic association for 3D multi-object tracking(MOT)and improve the PMBM filter’s continuity by smoothing single target hypothesis with global hypothesis.It consists of two key parts.First,the PMBM tracker based on sets of tracklets is implemented to realize probabilistic fusion of disordered measure-ments.Second,the confidence of tracklets is smoothed through a smoothing-while-filtering approach.Extensive MOT tests on nuScenes tracking dataset demonstrate that the proposed method achieves superior performance in different modalities.展开更多
文摘Located in the eastern portion of the Xing'an-Mongolian Orogenic Belt (XMOB), the Xinkailing-Kele complex has previously been considered to be Precambrian metamorphic rocks, mainly according to its relatively high metamorphic grade. Our filed observation, however, revealed that the complex is composed mainly of metamorphic rocks (Kele complex), tectono-schists (“Xinkailing Group”),and granitoids (Xinkailing granitic complex). Dating on these rocks using advanced SHRIMP zircon U-Pb technique indicates that: (1) Biotite-plagioclase gneiss from the Kele complex has a protolith age of 337±7Ma (2σ) and a metamorphic age of 216±3Ma (2σ); (2) the tectono-schist of the “Xinkailing Group” gave a magmatic age of 292±6Ma (2σ), indicative of felsic volcanic protolith of the schist formed in Late Paleozoic time; and (3) the Menluhedingzi and Lengchuan granites of the Xinkailing granitic complex were emplaced at167±4 (20σ) and 164±4Ma (2σ), respectively. These results suggest that the Xinkailing-Kele complex is not Precambrian metamorphic rocks and the so-called Precambrian “Nenji-ang Block” does essentially not exist. In combination with regional geological data, we propose that the Kele metamorphic complex is likely related to a collisional tectonism that took place in Triassic lime, as indicted by its metamorphic age of 216±3Ma. The Xinkailing granitic complex was emplaced along the collisional zone during Mid-Jurassic time，likely in a post-orogenic or anorogenic setting.
基金supported by the National Natural Science Foundation of China(Grant No.40234045)the Knowledge Innovation Project of the Chinese Academy of Sciences(Grant No.KZCX 2-104).
文摘The Xilin Gol Complex, consisting of deformed and metamorphosed rocks, was exposed as a large geological unit within the Central Asian Orogenic Belt, but its forming and subsequent deformed and metamorphic time has been an issue of little consensus. Petrographic analyses and SHRIMP dating on biotite-plagioclase gneiss, one of the ma-jor rocks within the Xilin Gol Complex, in southeast Xilinhot City, Inner Mongolia, China, where the Xilin Gol Complex was identified and named, yield its lower limit age of 437 3 Ma (2s ) by its magmatic zircon SHRIMP U-Pb dating, and an upper limit age of 316 3Ma (2s ), which was constrained by SHRIMP dating of magmatic zircons from adjacent un-deformed garnet-bearing granite which intruded the Com-plex. The Complex was thus determined to be formed and subsequently deformed/metamorphosed from the late Ordovi-cian-early Silurian to the mid-Carboniferous. Consequently, it is not the Precambrian terrane as previously considered by most geologists. More or less, the major rock——biotite- plagioclase gneiss within the Complex is more likely to be Paleozoic fore-arc turbidite formation before metamorphism and intensive deformation, in which the detrital zircons gave sporadic Precambrian ages as old as up to 3.1 Ga. The source of the turbidite formation is multiple, which may be derived either from the North China Craton, or from the South- Mongolia Micro-continent, or probably came from a poten-tial and undiscovered in situ terranes aged 600—800 Ma or even up to ca 3.1 Ga near the Complex.
基金supported by grants from the Technology Development Project (No. 201505022)the NSFC Shandong Joint Fund (No. U1406402)National Natural Science Foundation of China (No. 31371759)
文摘The antiviral activity in vitro and in vivo and the effect of the immune system of two fucoidan fractions with low molecular weight and different sulfate content from Laminaria japonica(LMW fucoidans) were investigated in order to examine the possible mechanism. In vitro, I-type influenza virus, adenovirus and Parainfluenza virus I were used to infect Hep-2, Hela and MDCK cells, respectively. And 50% tissue culture infective dose was calculated to detect the antiviral activity of two LMW fucoidans. The results indicated that compared with the control group, 2 kinds of LMW fucoidans had remarkable antiviral activity in vitro in middle and high doses, while at low doses, the antiviral activity of 2 kinds of LMW fucoidans was not statistically different from that in the blank control group. And there was no statistically difference between two LMW fucoidans in antiviral activity. In vivo, LMW fucoidans could prolong the survival time of virus-infected mice, and could improve the lung index of virus-infected mice significantly, which have statistical differences with the control group significantly(p < 0.01). However, the survival time of the two LMW fucoidans was not statistically significant(p > 0.05). In this study, it was shown that both of two LMW fucoidans(LF1, LF2) could increase the thymus index, spleen index, phagocytic index, phagocytosis coefficient and half hemolysin value in middle and high doses, which suggested that LMW fucoidans could play an antiviral role by improving the quality of immune organs, improving immune cell phagocytosis and humoral immunity.
基金supported by the Special Fund for Clinical Scientific Research of Shandong Medical Association(No.YXH2020ZX058).
文摘This study was carried out explore the mechanism underlying the inhibition of platelet activation by kelp fucoidans in deep venous thrombosis(DVT)mouse.In the control and sham mice,the walls of deep vein were regular and smooth with intact intima,myometrium and adventitia.The blood vessel was wrapped with the tissue and there was no thrombosis in the lumen.In the DVT model,the wall was uneven with thicken intima,myometrium and adventitia.After treated with fucoidans LF1 and LF2,the thrombus was dissolved and the blood vessel was recanalized.Compared with the control group,the ROS content,ET-1 and VWF content and the expression of PKC-βand NF-κB in the model were significantly higher(P<0.05);these levels were significantly reduced following treatments with LF2 and LF1.Compared with H_(2)O_(2)treated-HUVECs,combined LF1 and LF2 treatment resulted in significant decrease in the expression of PKC-β,NF-κB,VWF and TM protein(P<0.05).It is clear that LF1 and LF2 reduces DVT-induced ET-1,VWF and TM expressions and production of ROS,thus inhibiting the activation of PKC-β/NF-κB signal pathway and the activation of coagulation system and ultimately reducing the formation of venous thrombus.
基金supported by the Project of High Technology Research and Development of China(2006AA03A101 and 2006AA03A103)the National Natural Science Foundation of China(60676004)the Science Research Program of Shanghai(05PJ14100 and 06dz11402).
文摘γ-LiAlO2 single crystal is a promising substrate for GaN heteroepitaxy. In this paper, we present the growth of large-sized LiAlO2 crystal by modified Czochralski method. The crystal quality was characterized by high-resolution X-ray diffraction and chemical etching. The results show that the as-grown crystal has perfect quality with the full width at half maximum （FWHM） of 17.7-22.6 arcsec and etch pits density of （0.3- 2.2）×10^4 cm^-2 throughout the crystal boule. The bottom of the crystal boule shows the best quality. The optical transmission spectra from UV to IR exhibits that the crystal is transparent from 0.2 to 5.5μm and becomes completely absorbing around 6.7μm wavelength, The optical absorption edge in near UV region is about 191 nm.
基金supported by International Science and Technology Cooperation Program of China(2019YFE0100200)in part by National Natural Science Foundation of China(61903220)National Natural Science Foundation of China(U1864203).
文摘Real driving scenarios,due to occlusions and disturbances,provide disordered and noisy measurements,which makes the task of multi-object tracking quite challenging.Conventional approach is to find deterministic data association;however,it has unstable performance in high clutter density.This paper proposes a novel probabilistic tracklet-enhanced multiple object tracker(PTMOT),which integrates Poisson multi-Bernoulli mixture(PMBM)filter with confidence of tracklets.The proposed method is able to realize efficient and robust probabilistic association for 3D multi-object tracking(MOT)and improve the PMBM filter’s continuity by smoothing single target hypothesis with global hypothesis.It consists of two key parts.First,the PMBM tracker based on sets of tracklets is implemented to realize probabilistic fusion of disordered measure-ments.Second,the confidence of tracklets is smoothed through a smoothing-while-filtering approach.Extensive MOT tests on nuScenes tracking dataset demonstrate that the proposed method achieves superior performance in different modalities.
基金supported in part by the National Natural Science Foundation of China (Grant Nos.61375063,51478049, 61773404and 11301549)in part by the Major Scientific and Technological Special Program of Hunan Province,China (2015GK1001-1).
