Piper (1944) diagram has been the basis for several important interpretations of the hydrogeochemical data. As seen in this diagram, most natural waters contain relatively few dissolved constituents, with cations (met...Piper (1944) diagram has been the basis for several important interpretations of the hydrogeochemical data. As seen in this diagram, most natural waters contain relatively few dissolved constituents, with cations (metals or bases) and anions (acid radicles) in chemical equilibrium with one another. Apart from the facies representation, the composition of the mixed sample can be identified in terms of the composition of the parental solution. To bring out this advantage of the Piper diagram, a study was conducted in the Kalpakkam region of Tamilnadu, South India. By taking the geology and water table into consideration, two sample locations were selected as parent solution and third one as the mixture sample. All three samples were analyzed for calcium (Ca), magnesium (Mg), sodium (Na), potassium (K), chloride (Cl), sulphate (SO4) and phosphate (PO4) by Ion Chromatograph (Metrohm IC 861). HCO3 was determined by volumetric titration. The Piper diagram shows that parent solutions clustered towards Na-Mg-Ca-HCO3-Cl and Na-HCO3 facies, and the mixing sample belongs to Na-Mg-HCO3 facies. Phreeqc interac-tive (Ver 2.8) along with the original composition of the mixture sample was used to correlate the mixing proportion identified by the Piper diagram.展开更多
Purpose: Although proximal stability of the trunk is a prerequisite for balance and gait, to determine the role of trunk rehabilitation on trunk control, balance and gait in patients with chronic stroke is yet unknown...Purpose: Although proximal stability of the trunk is a prerequisite for balance and gait, to determine the role of trunk rehabilitation on trunk control, balance and gait in patients with chronic stroke is yet unknown. Method: Fifteen sub-jects (post-stroke duration (3.53 ± 2.98) years) who had the ability to walk 10 meters independently with or without a walking aid;scoring ≤ 21 on Trunk Impairment Scale (TIS), participated in a selective trunk muscle exercise regime, consisting of 45 minutes training per day, four days a week, and for four weeks duration in an outpatient stroke reha-bilitation centre. Results: The overall effect size index for trunk rehabilitation was 1.07. This study showed large effect size index for Trunk Impairment Scale (1.75), Berg Balance Scale (1.65) than for gait variables (0.65). After trunk rehabilitation, there was a significant improvement for gait speed (p= 0.015), cadence (p= 0.001) and gait symmetry (p=0.019) in patients with chronic stroke. In addition, all the spatial gait parameters had a significant change post-intervention. There was no significant change in temporal gait parameters with the exception of affected single limb support time. The level of significance was set at p < 0.05. Conclusion: The exercises consisted of selective trunk movement of the upper and the lower part of trunk had shown larger effect size index for trunk control and balance than for gait in patients with chronic stroke. Future randomized controlled studies incorporating large sample size would provide insight into the effectiveness and clinical relevance of this intervention.展开更多
Superalloy C-276 is known to be prone to hot cracking during fusion welding by Gas Tungsten Arc method. Microsegregation occurring during cooling of fusion zone with consequent appearance of topologically close-packed...Superalloy C-276 is known to be prone to hot cracking during fusion welding by Gas Tungsten Arc method. Microsegregation occurring during cooling of fusion zone with consequent appearance of topologically close-packed phases P and IX has been held responsible for the observed hot cracking. The present work investigated the possibility of suppressing the microsegregation in weldments by resorting to current pulse. Weldments were made by continuous current gas tungsten arc welding and pulsed current gas tungsten arc welding using ERNiCrMo-4 filler wire. The weld joints were studied with respect to microstructure, microsegregation, and mechanical properties. Optical microscopy and scanning electron microscopy were employed to study the microstructure. Energy-Dispersive X-ray Spectroscopy was carried out to evaluate the extent of microsegregation. Tensile testing was carried out to determine the strength and ductility. The results show that the joints fabricated with pulsed current gave rise to narrower welds with practically no heat affected zone, a refined microstructure in the fusion zone, reduced microsegregation, and superior combination of mechanical properties.展开更多
As the first and rate-limiting enzyme of proline degradation, PROLINE DEHYDROGENASE1 （PDH1） is tightly regulated during plant stress responses, including induction under hypoosmolarity and repression under water def...As the first and rate-limiting enzyme of proline degradation, PROLINE DEHYDROGENASE1 （PDH1） is tightly regulated during plant stress responses, including induction under hypoosmolarity and repression under water deficit. The plant receptor histidine kinases AHKs, elements of the two-component system （TCS） in Arabidopsis thaliana, are pro- posed to function in water stress responses by regulating different stress-responsive genes. However, little information is available concerning AHK phosphorelay-mediated downstream signaling. Here we show that the Arabidopsis type-B response regulator 18 （ARR18） functions as a positive osmotic stress response regulator in Arabidopsis seeds and affects the activity of the PDH1 promoter, known to be controlled by C-group bZlP transcription factors. Moreover, direct physical interaction of ARR18 with bZIP63 was identified and shown to be dependent on phosphorylation of the conserved aspar- tate residue in the ARR18 receiver domain. We further show that bZlP63 itself functions as a negative regulator of seed germination upon osmotic stress. Using reporter gene assays in protoplasts, we demonstrated that ARR18 interaction negatively interferes with the transcriptional activity of bZIP63 on the PDH1 promoter. Our findings provide new insight into the function of ARR18 and bZIP63 as antagonistic regulators of gene expression in Arabidopsis.展开更多
Bismuth molybdate （Bi2MoO6） nano-particles （NPs） were synthesized using bismuth nitrate, ammonium molybdate, citric acid and ethyl cellulose by a simple sol-gel method. The structure, morphology, opto-magnetic and...Bismuth molybdate （Bi2MoO6） nano-particles （NPs） were synthesized using bismuth nitrate, ammonium molybdate, citric acid and ethyl cellulose by a simple sol-gel method. The structure, morphology, opto-magnetic and photocatalytic properties of the obtained powder were characterized by X-ray diffraction （XRD）, Fourier transform infrared （FT-IR） spectra, high resolution scanning electron microscopy （HRSEM）, energy dispersive X-ray （EDX）, ultraviolet-visible diffuse reflectance spectra （DRS）, photoluminescence （PL） spectra and vibrating sample magnetometer （VSM） techniques. The XRD, FT-IR and EDX results indicate that the resultant powder is pure and single phase crystalline Bi2MoO6 with orthorhombic structure. The HRSEM image shows that the morphology of obtained powder consists with well defined nano-particles structure. The VSM results show superparamagnetic behavior of the obtained nano-particles. The photocatalytic activity of Bi2MoO6 nano-particles was performed. The addition of TiO2 catalyst enhances the photocatalytic activity of Bi2MoO6 nano-particles. The catalysts Bi2MoO6, TiO2 and mixed oxide catalyst Bi2MoO6-TiO2 nano-composites （NCs） were tested for the photocatalytic degradation （PCD） of 4-chlorophenol （4-CP）. It is found that the PCD efficiency of Bi2MoO6-TiO2 NCs is higher than that of pure Bi2MoO6 and TiO2 catalysts.展开更多
Functional textiles that promote daily comfort and productivity must efficiently release body sweats and transmit radiative heat through sweat evaporation and mid-infrared radiation(MIR)(8–13μm).However,most of the ...Functional textiles that promote daily comfort and productivity must efficiently release body sweats and transmit radiative heat through sweat evaporation and mid-infrared radiation(MIR)(8–13μm).However,most of the traditional clothing cannot provide simultaneous sweat evaporation and mid-infrared radiation transmission efficiently,leading to a poor design of personal cooling wearables.Herein,an evaporative/radiative integrated functional fibrous electrospun membrane is meticulously designed and controllably fabricated via facile electrospinning technology for personal cooling management.The developed membrane can be applied as a smart wearable with distinct personal thermal management applications.The promising temperature and humidity responsive vapor transmission of the membrane grants 1.2 times of evaporative cooling than that of traditional cotton.Besides,based on its high mid-infrared radiation transmission(53%)property in the range of 8–13μm,the as-spun membrane provides extra cooling of 1.5°C than that of cotton.Moreover,the building energy saving performances demonstrated that 47.1%annual building cooling can be achieved using the developed electrospun membrane.In general,the evaporative/radiative electrospun membrane creates a passive cooling microclimate for the human body,meeting the growing demand of wearable for personal cooling.展开更多
Nickel molybdate(NiMoO4)nanoparticles(NPs)were synthesized by sol-gel method.Utilizing water as solvent providescrystalline nanostructures.These nanocrystals were structurally characterized by X-ray diffraction,energy...Nickel molybdate(NiMoO4)nanoparticles(NPs)were synthesized by sol-gel method.Utilizing water as solvent providescrystalline nanostructures.These nanocrystals were structurally characterized by X-ray diffraction,energy dispersive X-ray analysis(EDX),and Fourier transform infrared spectra.Compositional stoichiometry was confirmed by EDX technique.The size and shapewere observed by scanning electron microscopy(SEM)and transmission electron microscope(TEM).It was found that the obtainedNPs were pure and single phase crystalline with monoclinic structure.The optical properties were studied by ultraviolet-visiblediffuse reflectance spectroscopy(UV-Vis-DRS)and photoluminescence(PL)measurements at room temperature.The magneticproperties were studied by vibrating sample magnetometer(VSM)and results showed superparamagnetic behavior of the obtainednanoparticles.Photocatalytic activity of NiMoO4was studied.The photocatalytic activity of NiMoO4was enhanced with the additionof TiO2.The catalysts NiMoO4,TiO2and NiMoO4-TiO2nanocomposites(NC)were tested for photocatalytic degradation(PCD)of4-chlorophenol(4-CP).It was found that PCD efficiency of NiMoO4-TiO2NC was higher than that of pure NiMoO4and TiO2.展开更多
Objective:Ureteral stents are customarily inserted to facilitate urinary drainage,but they come with their own glitches of being forgotten and/or encrusted leading to serious consequences.The present study aimed to re...Objective:Ureteral stents are customarily inserted to facilitate urinary drainage,but they come with their own glitches of being forgotten and/or encrusted leading to serious consequences.The present study aimed to report the complications in patients with forgotten and encrusted stents according to the Clavien-Dindo system specific to urological procedures and identify the factors leading to high-grade(Clavien-Dindo Grade 4A or above)complications.Methods:The hospital records of patients with forgotten encrusted double-J stents over a period of 8 years were reviewed.The parameters recorded included patient demographics,indwelling time,need for percutaneous nephrostomy,hemodialysis,urine culture,blood culture,total blood counts,serum creatinine,radiologic findings,management techniques,number of surgical interventions,modified Clavien-Dindo complications,follow-up,and mortality,if any.Results:Forty patients were included in the study.The median age was 52(range 6-85)years.Of the total,25(62.5%)patients had a“significant”stent load;31(77.5%)had renal failure or acute kidney injury on presentation;19(47.5%)patients had sepsis at presentation.Among the patients presented with sepsis,11(57.9%)patients demonstrated a positive urine culture;and 7/11(63.6%)patients exhibited pan-resistant organisms.Twelve out of 40(30.0%)patients in our series developed high-grade Clavien-Dindo complications.On univariate analysis,sepsis at presentation(p=0.007),stent load(p=0.031),diabetes(p=0.023),positive urine culture(p=0.007),and stent indwelling time of more than 1 year(p=0.031)were found to be significant.On multivariate logistic regression analysis,sepsis at presentation(p=0.017)and positive urine culture(p=0.016)were significant predictors for high-grade complications.Conclusion:It is prudent to identify specific risk factors,namely sepsis at presentation and positive urine culture to triage and optimize these patients before surgical management.展开更多
Cu-Ni alloy nanoparticles were prepared by a microwave combustion method with the molar ratios of CU2＋ to Ni2＋ as 3：7, 4：6, 5：5, 6：4 and 7：3. The as-prepared samples were characterized by XRD, HR-SEM, EDX and V...Cu-Ni alloy nanoparticles were prepared by a microwave combustion method with the molar ratios of CU2＋ to Ni2＋ as 3：7, 4：6, 5：5, 6：4 and 7：3. The as-prepared samples were characterized by XRD, HR-SEM, EDX and VSM. XRD and EDX analyses suggest the formation of pure alloy powders. The average crystallite sizes were found to be in the range of 21.56-33.25 nm. HR-SEM images show the clustered/agglomerated particle-like morphology structure. VSM results reveal that for low Ni content （CusNis, Cu6Ni4 and Cu7Ni3）, the system shows paramagnetic behaviors, whereas for high Ni content （Cu3Ni7 and Cu4Ni6）, it becomes ferromagnetic.展开更多
Background:Hard mineral and acid salt deposits that clump together in concentrated urine are known as kidney stones.A complicated chain of physicochemical events,including hyper saturation,nucleation,growth,aggrega-ti...Background:Hard mineral and acid salt deposits that clump together in concentrated urine are known as kidney stones.A complicated chain of physicochemical events,including hyper saturation,nucleation,growth,aggrega-tion,and retention in the urinary tract,leads to urolithiasis,the third most prevalent urinary tract issue.Numerous traditional medications and therapies are less successful in treating urolithiasis and frequently cause recurrences.Objective:The present study is focused on evaluating the anti-urolithiasis activities of the polyherbal formulation prepared from Spinacia oleracea L.and Coriandrum sativum L.seeds.Methods:To evaluating the anti-urolithiasis activities of the polyherbal formulation prepared from S.oleracea and C.sativum seeds against oxalate crystals by employing an in vitro inhibition,aggregation,and nucleation assay,employing a spectrophotometer followed by microscopic observation,and further monitored by egg semiperme-able membrane model,using cystone as a standard drug.Results:In the present work,the alkaloids,glycosides,flavonoids,glycosides,phenols,saponins,steroids,tannins,terpenoids,and triterpenoids were found in the extracts of S.oleracea and C.sativum.The in vitro assays in the present study clearly indicated that all the mixture extracts readily prevented crystal nucleation,growth and ag-gregation.The aqueous extract of the mixture inhibited significant inhibitory potential against the crystallization process.Conclusion:It can be said that the phyto-constituents enriched homemade preparation possibly will be used as a medication for the management of kidney stones by dissolving the oxalate stone in the kidney.展开更多
This exploration acquaints a momentous methodology with custom chatbot improvement that focuses on pro-ficiency close by viability.We accomplish this by joining three key innovations:LangChain,Retrieval Augmented Gene...This exploration acquaints a momentous methodology with custom chatbot improvement that focuses on pro-ficiency close by viability.We accomplish this by joining three key innovations:LangChain,Retrieval Augmented Generation(RAG),and enormous language models(LLMs)tweaked with execution proficient strategies like LoRA and QLoRA.LangChain takes into consideration fastidious fitting of chatbots to explicit purposes,guaranteeing engaged and important collaborations with clients.RAG’s web scratching capacities engage these chatbots to get to a tremendous store of data,empowering them to give exhaustive and enlightening reactions to requests.This recovered data is then decisively woven into reaction age utilizing LLMs that have been calibrated with an emphasis on execution productivity.This combination approach offers a triple advantage:further developed viability,upgraded client experience,and extended admittance to data.Chatbots become proficient at taking care of client questions precisely and productively,while instructive and logically pertinent reactions make a more regular and drawing in cooperation for clients.At last,web scratching enables chatbots to address a more extensive assortment of requests by conceding them admittance to a more extensive information base.By digging into the complexities of execution proficient LLM calibrating and underlining the basic job of web-scratched information,this examination offers a critical commitment to propelling custom chatbot plan and execution.The subsequent chatbots feature the monstrous capability of these advancements in making enlightening,easy to understand,and effective conversational specialists,eventually changing the manner in which clients cooperate with chatbots.展开更多
Nanocrystalline SnO<sub>2</sub> and CuO doped with SnO<sub>2</sub> were prepared by the co-precipitation method and characterized for different physiochemical properties and microbiological act...Nanocrystalline SnO<sub>2</sub> and CuO doped with SnO<sub>2</sub> were prepared by the co-precipitation method and characterized for different physiochemical properties and microbiological activity. The composition and morphological formation were characterized by XRD, HRTEM, Raman, FTIR, and UV-vis spectroscopy. The Powder X-ray analysis reveals that Sn4+ ions have substituted the Cu<sup>2+</sup> ions without changing the monoclinic structure of SnO<sub>2</sub> but the average particle size of the SnO<sub>2</sub> and CuO doped SnO<sub>2</sub> samples from 11 and 5 nm respectively. However, it exhibits an inhibiting strong bacterial growth against tested bacterial strains.展开更多
To better elucidate epigenetic mechanisms that correlate with the dynamic gene expression program observed upon T-cell differentiation, we investigated the genomic landscape of histone modifications in naive and memor...To better elucidate epigenetic mechanisms that correlate with the dynamic gene expression program observed upon T-cell differentiation, we investigated the genomic landscape of histone modifications in naive and memory CD8＋ T cells. Using a ChlP-Seq approach coupled with global gene expression profiling, we generated genome-wide histone H3 lysine 4 （H3K4me3） and H3 lysine 27 （H3K27me3） trimethylation maps in naive, T memory stem cells, central memory cells, and effector memory cells in order to gain insight into how histone architecture is remodeled during T cell differentiation. We show that H3K4me3 histone modifications are associated with activation of genes, while H3K27me3 is negatively correlated with gene expression at canonical loci and enhancers associated with T-cell metabolism, effector function, and memory. Our results also reveal histone modifications and gene expression signatures that distinguish the recently identified T memory stem cells from other CD8＋ T-cell subsets. Taken together, our results suggest that CD8＋ lymphocytes undergo chromatin remodeling in a progressive fashion. These findings have major implications for our understanding of peripheral T-cell ontogeny and the formation of immunological memory.展开更多
12-Tungstophosphoric heteropoly acid(TPA) with a Keggin structure was introduced into Al-incorporated mesoporous molecular sieves(AlSBA-15) by the incipient wetness method.The materials were characterized by X-ray dif...12-Tungstophosphoric heteropoly acid(TPA) with a Keggin structure was introduced into Al-incorporated mesoporous molecular sieves(AlSBA-15) by the incipient wetness method.The materials were characterized by X-ray diffraction,nitrogen adsorption,scanning electron microscopy,UV-Vis diffuse reflectance and Raman spectroscopy,which confirmed the Keggin and mesopore structure.Its catalytic activity was evaluated under solvent-free conditions in the liquid phase at 333-383 K for the propionylation of anisole with propionic anhydride.The catalysts used were AlSBA-15,10%,20%,and 40% TPA/AlSBA-15,and 20% TPA/MCM-48.In the propionylation of anisole with propionic anhydride,the substitution occurred predominantly at the para position.The 20% TPA/AlSBA-15 catalyst gave a total product yield of 48% with 98% selectivity towards 4-methoxypropiophenone.The regenerability of the catalyst was also studied and was found to be excellent.展开更多
The booming electronics itself carries an impact on power quality. Superconducting Magnetic Energy Storage (SMES) is proposed to enhance power quality in three-phase systems under various loads. This paper aimed to co...The booming electronics itself carries an impact on power quality. Superconducting Magnetic Energy Storage (SMES) is proposed to enhance power quality in three-phase systems under various loads. This paper aimed to compensate the voltage sags under various faults in the grid systems. The SMES is selected as an energy storage unit to improve the capability of voltage sag compensation. Optimized Dual Fuzzy Flow (ODFF) logic controller is designed to prevent the voltage sag time during excessive phase voltage variation. Hence the proposed controller strategy reduces the total harmonic distortion during various fault conditions. To regulate the contribution of active power, the least possible value is improved using ODFF. The depth of voltage sags compensation is achieved by the over modulation and an iterative loop is designed in the control block. While protecting sensitive loads from voltage disturbances, and sags initiated by the power system, the proposed configuration is advantageous for an industrial implementation. It is found that the proposed method can result in more than 50% additional sag support time when compared with the previous methods such as PI and PSO. Utilizing MATLAB Simulink, compensation of sag and minimization of THD is established, and the simulation tests are performed to evaluate the performance of the proposed control method.展开更多
The effects of process variables in Simultaneous Saccharification and Fermentation (SSF) of wheat bran flour were studied in bulk fermentation using a coculture of Aspergillus niger - Kluveromyces marxianus. The effec...The effects of process variables in Simultaneous Saccharification and Fermentation (SSF) of wheat bran flour were studied in bulk fermentation using a coculture of Aspergillus niger - Kluveromyces marxianus. The effect of substrate density, pH, temperature, and enzyme concentration on wheat bran was predicted by designing experiments in which a single parameter is varied keeping other variables at a constant level. The above parameters were optimized for a batch culture in a fermentor. Optimal values for substrate concentration, pH, temperature, and enzyme concentration during processing were 200 g/l, 5.5, 65°C, and 7.5 IU, respectively. In pre-treatment experiments, the concentration of enzymes and the pre-treatment temperature are highly correlated. The influence of pH, temperature, and substrate density on ethanol production was investigated. Temperature pH was determined as optimal, 32°C and 5.5, respectively. After 48 hours of fermentation at optimum pH, a solution of wheat bran containing a maximum of 6% starch produces a maximum of 22.9 g/l ethanol.展开更多
Electrical Capacitance Tomography (ECT) determines the dielectric permittivity of the interior object depending on the measurements of exterior capacitance. Generally, the electrodes are placed outside the PVC cylinde...Electrical Capacitance Tomography (ECT) determines the dielectric permittivity of the interior object depending on the measurements of exterior capacitance. Generally, the electrodes are placed outside the PVC cylinder where the medium to be imaged is present;but in ECT using inter-electrode capacitance measurements can be achieved by placing inside of the dielectric medium. In the proposed ECT system, the ECT sensor is modeled using ANSYS software and the model is implemented in real ECT system. For each step of measurement, a stable AC signal is applied to a pair of electrodes that form a capacitor. The novel system is to measure the capacitance range variation in picofarad and the corresponding voltage ranges from 1 volt to 4 volts. The switching speed of all combinational electrodes is implemented using embedded system to achieve higher speed performance of AC ECT system which eliminates the drift and stray capacitance error. This is yielding the original image of unknown multiphase medium inside the electrodes using Lab VIEW. This paper investigates several advantages such as improved overall system performance;simple structure, avoids stray capacitance effect, reduces the drift problem and achieves high signal to noise ratio.展开更多
This paper presents an intelligent controller employing Adaptive Neuro-Fuzzy Inference System (ANFIS) for extracting maximum power from the wind energy conversion system even during the change in the wind speed condit...This paper presents an intelligent controller employing Adaptive Neuro-Fuzzy Inference System (ANFIS) for extracting maximum power from the wind energy conversion system even during the change in the wind speed conditions with improved quality of power. The proposed induction generator with multilevel inverter along with intelligent controller based Maximum Power Point Tracking (MPPT) technique aims at integrating winds system with improved maximum power injection and minimum harmonic issues. The proposed method will improve the power quality which is delivered to the grid in terms of harmonic, and inject the maximum power to the grid. To validate the effectiveness of the proposed control strategy, ANFIS controller, Fuzzy Inference System (FIS) and without MPPT controller have been presented and tested using MATLAB/Simulink environment.展开更多
Vedic mathematics is the system of mathematics followed in ancient Indian and it is applied in various mathematical branches. The word “Vedic” represents the storehouse of all knowledge. Because using Vedic Mathemat...Vedic mathematics is the system of mathematics followed in ancient Indian and it is applied in various mathematical branches. The word “Vedic” represents the storehouse of all knowledge. Because using Vedic Mathematics, the arithmetical problems are solved easily. The mathematical algorithms are formed from 16 sutras and 13 up-sutras. But there are some limitations in each sutra. Here, two sutras Nikhilam sutra and Karatsuba algorithm are considered. In this research paper, a novel algorithm for binary multiplication based on Vedic mathematics is designed using bit reduction technique. Though Nikhilam sutra is used for multiplication, it is not used in all applications. Because it is special in multiplication. The remainder is derived from this sutra by reducing the remainder bit size to N-2 bit. Here, the number of bits of the remainder is constantly maintained as N-2 bits. By using Karatsuba algorithm, the overall structure of the multiplier is designed. Unlike the conventional Karatsuba algorithm, the proposed algorithm requires only one multiplier with N-2 bits only. The speed of the proposed algorithm is improved with balancing the area and the power. Even though there is a deviation in lower order bits, this method shows larger difference in higher bit lengths.展开更多
文摘Piper (1944) diagram has been the basis for several important interpretations of the hydrogeochemical data. As seen in this diagram, most natural waters contain relatively few dissolved constituents, with cations (metals or bases) and anions (acid radicles) in chemical equilibrium with one another. Apart from the facies representation, the composition of the mixed sample can be identified in terms of the composition of the parental solution. To bring out this advantage of the Piper diagram, a study was conducted in the Kalpakkam region of Tamilnadu, South India. By taking the geology and water table into consideration, two sample locations were selected as parent solution and third one as the mixture sample. All three samples were analyzed for calcium (Ca), magnesium (Mg), sodium (Na), potassium (K), chloride (Cl), sulphate (SO4) and phosphate (PO4) by Ion Chromatograph (Metrohm IC 861). HCO3 was determined by volumetric titration. The Piper diagram shows that parent solutions clustered towards Na-Mg-Ca-HCO3-Cl and Na-HCO3 facies, and the mixing sample belongs to Na-Mg-HCO3 facies. Phreeqc interac-tive (Ver 2.8) along with the original composition of the mixture sample was used to correlate the mixing proportion identified by the Piper diagram.
文摘Purpose: Although proximal stability of the trunk is a prerequisite for balance and gait, to determine the role of trunk rehabilitation on trunk control, balance and gait in patients with chronic stroke is yet unknown. Method: Fifteen sub-jects (post-stroke duration (3.53 ± 2.98) years) who had the ability to walk 10 meters independently with or without a walking aid;scoring ≤ 21 on Trunk Impairment Scale (TIS), participated in a selective trunk muscle exercise regime, consisting of 45 minutes training per day, four days a week, and for four weeks duration in an outpatient stroke reha-bilitation centre. Results: The overall effect size index for trunk rehabilitation was 1.07. This study showed large effect size index for Trunk Impairment Scale (1.75), Berg Balance Scale (1.65) than for gait variables (0.65). After trunk rehabilitation, there was a significant improvement for gait speed (p= 0.015), cadence (p= 0.001) and gait symmetry (p=0.019) in patients with chronic stroke. In addition, all the spatial gait parameters had a significant change post-intervention. There was no significant change in temporal gait parameters with the exception of affected single limb support time. The level of significance was set at p < 0.05. Conclusion: The exercises consisted of selective trunk movement of the upper and the lower part of trunk had shown larger effect size index for trunk control and balance than for gait in patients with chronic stroke. Future randomized controlled studies incorporating large sample size would provide insight into the effectiveness and clinical relevance of this intervention.
基金supported by the Defence Research Development organization (DRDO) (No. ERIP/ ER/1103952/M/01/1403)Department of Science and Technology for the funding received from them under the FIST programme
文摘Superalloy C-276 is known to be prone to hot cracking during fusion welding by Gas Tungsten Arc method. Microsegregation occurring during cooling of fusion zone with consequent appearance of topologically close-packed phases P and IX has been held responsible for the observed hot cracking. The present work investigated the possibility of suppressing the microsegregation in weldments by resorting to current pulse. Weldments were made by continuous current gas tungsten arc welding and pulsed current gas tungsten arc welding using ERNiCrMo-4 filler wire. The weld joints were studied with respect to microstructure, microsegregation, and mechanical properties. Optical microscopy and scanning electron microscopy were employed to study the microstructure. Energy-Dispersive X-ray Spectroscopy was carried out to evaluate the extent of microsegregation. Tensile testing was carried out to determine the strength and ductility. The results show that the joints fabricated with pulsed current gave rise to narrower welds with practically no heat affected zone, a refined microstructure in the fusion zone, reduced microsegregation, and superior combination of mechanical properties.
文摘As the first and rate-limiting enzyme of proline degradation, PROLINE DEHYDROGENASE1 （PDH1） is tightly regulated during plant stress responses, including induction under hypoosmolarity and repression under water deficit. The plant receptor histidine kinases AHKs, elements of the two-component system （TCS） in Arabidopsis thaliana, are pro- posed to function in water stress responses by regulating different stress-responsive genes. However, little information is available concerning AHK phosphorelay-mediated downstream signaling. Here we show that the Arabidopsis type-B response regulator 18 （ARR18） functions as a positive osmotic stress response regulator in Arabidopsis seeds and affects the activity of the PDH1 promoter, known to be controlled by C-group bZlP transcription factors. Moreover, direct physical interaction of ARR18 with bZIP63 was identified and shown to be dependent on phosphorylation of the conserved aspar- tate residue in the ARR18 receiver domain. We further show that bZlP63 itself functions as a negative regulator of seed germination upon osmotic stress. Using reporter gene assays in protoplasts, we demonstrated that ARR18 interaction negatively interferes with the transcriptional activity of bZIP63 on the PDH1 promoter. Our findings provide new insight into the function of ARR18 and bZIP63 as antagonistic regulators of gene expression in Arabidopsis.
文摘Bismuth molybdate （Bi2MoO6） nano-particles （NPs） were synthesized using bismuth nitrate, ammonium molybdate, citric acid and ethyl cellulose by a simple sol-gel method. The structure, morphology, opto-magnetic and photocatalytic properties of the obtained powder were characterized by X-ray diffraction （XRD）, Fourier transform infrared （FT-IR） spectra, high resolution scanning electron microscopy （HRSEM）, energy dispersive X-ray （EDX）, ultraviolet-visible diffuse reflectance spectra （DRS）, photoluminescence （PL） spectra and vibrating sample magnetometer （VSM） techniques. The XRD, FT-IR and EDX results indicate that the resultant powder is pure and single phase crystalline Bi2MoO6 with orthorhombic structure. The HRSEM image shows that the morphology of obtained powder consists with well defined nano-particles structure. The VSM results show superparamagnetic behavior of the obtained nano-particles. The photocatalytic activity of Bi2MoO6 nano-particles was performed. The addition of TiO2 catalyst enhances the photocatalytic activity of Bi2MoO6 nano-particles. The catalysts Bi2MoO6, TiO2 and mixed oxide catalyst Bi2MoO6-TiO2 nano-composites （NCs） were tested for the photocatalytic degradation （PCD） of 4-chlorophenol （4-CP）. It is found that the PCD efficiency of Bi2MoO6-TiO2 NCs is higher than that of pure Bi2MoO6 and TiO2 catalysts.
基金the Contract Research(Development of Breathable Fabrics with Nano-Electrospun Membrane,CityU ref.:9231419)the National Natural Science Foundation of China(Study of Multi-Responsive Shape Memory Polyurethane Nanocomposites Inspired by Natural Fibers,Grant No.51673162)Start-up Grant of CityU(Laboratory of Wearable Materials for Healthcare,Grant No.9380116).
文摘Functional textiles that promote daily comfort and productivity must efficiently release body sweats and transmit radiative heat through sweat evaporation and mid-infrared radiation(MIR)(8–13μm).However,most of the traditional clothing cannot provide simultaneous sweat evaporation and mid-infrared radiation transmission efficiently,leading to a poor design of personal cooling wearables.Herein,an evaporative/radiative integrated functional fibrous electrospun membrane is meticulously designed and controllably fabricated via facile electrospinning technology for personal cooling management.The developed membrane can be applied as a smart wearable with distinct personal thermal management applications.The promising temperature and humidity responsive vapor transmission of the membrane grants 1.2 times of evaporative cooling than that of traditional cotton.Besides,based on its high mid-infrared radiation transmission(53%)property in the range of 8–13μm,the as-spun membrane provides extra cooling of 1.5°C than that of cotton.Moreover,the building energy saving performances demonstrated that 47.1%annual building cooling can be achieved using the developed electrospun membrane.In general,the evaporative/radiative electrospun membrane creates a passive cooling microclimate for the human body,meeting the growing demand of wearable for personal cooling.
基金support from the Caplin Point Laboratories Limited,Chennai,India
文摘Nickel molybdate(NiMoO4)nanoparticles(NPs)were synthesized by sol-gel method.Utilizing water as solvent providescrystalline nanostructures.These nanocrystals were structurally characterized by X-ray diffraction,energy dispersive X-ray analysis(EDX),and Fourier transform infrared spectra.Compositional stoichiometry was confirmed by EDX technique.The size and shapewere observed by scanning electron microscopy(SEM)and transmission electron microscope(TEM).It was found that the obtainedNPs were pure and single phase crystalline with monoclinic structure.The optical properties were studied by ultraviolet-visiblediffuse reflectance spectroscopy(UV-Vis-DRS)and photoluminescence(PL)measurements at room temperature.The magneticproperties were studied by vibrating sample magnetometer(VSM)and results showed superparamagnetic behavior of the obtainednanoparticles.Photocatalytic activity of NiMoO4was studied.The photocatalytic activity of NiMoO4was enhanced with the additionof TiO2.The catalysts NiMoO4,TiO2and NiMoO4-TiO2nanocomposites(NC)were tested for photocatalytic degradation(PCD)of4-chlorophenol(4-CP).It was found that PCD efficiency of NiMoO4-TiO2NC was higher than that of pure NiMoO4and TiO2.
文摘Objective:Ureteral stents are customarily inserted to facilitate urinary drainage,but they come with their own glitches of being forgotten and/or encrusted leading to serious consequences.The present study aimed to report the complications in patients with forgotten and encrusted stents according to the Clavien-Dindo system specific to urological procedures and identify the factors leading to high-grade(Clavien-Dindo Grade 4A or above)complications.Methods:The hospital records of patients with forgotten encrusted double-J stents over a period of 8 years were reviewed.The parameters recorded included patient demographics,indwelling time,need for percutaneous nephrostomy,hemodialysis,urine culture,blood culture,total blood counts,serum creatinine,radiologic findings,management techniques,number of surgical interventions,modified Clavien-Dindo complications,follow-up,and mortality,if any.Results:Forty patients were included in the study.The median age was 52(range 6-85)years.Of the total,25(62.5%)patients had a“significant”stent load;31(77.5%)had renal failure or acute kidney injury on presentation;19(47.5%)patients had sepsis at presentation.Among the patients presented with sepsis,11(57.9%)patients demonstrated a positive urine culture;and 7/11(63.6%)patients exhibited pan-resistant organisms.Twelve out of 40(30.0%)patients in our series developed high-grade Clavien-Dindo complications.On univariate analysis,sepsis at presentation(p=0.007),stent load(p=0.031),diabetes(p=0.023),positive urine culture(p=0.007),and stent indwelling time of more than 1 year(p=0.031)were found to be significant.On multivariate logistic regression analysis,sepsis at presentation(p=0.017)and positive urine culture(p=0.016)were significant predictors for high-grade complications.Conclusion:It is prudent to identify specific risk factors,namely sepsis at presentation and positive urine culture to triage and optimize these patients before surgical management.
文摘Cu-Ni alloy nanoparticles were prepared by a microwave combustion method with the molar ratios of CU2＋ to Ni2＋ as 3：7, 4：6, 5：5, 6：4 and 7：3. The as-prepared samples were characterized by XRD, HR-SEM, EDX and VSM. XRD and EDX analyses suggest the formation of pure alloy powders. The average crystallite sizes were found to be in the range of 21.56-33.25 nm. HR-SEM images show the clustered/agglomerated particle-like morphology structure. VSM results reveal that for low Ni content （CusNis, Cu6Ni4 and Cu7Ni3）, the system shows paramagnetic behaviors, whereas for high Ni content （Cu3Ni7 and Cu4Ni6）, it becomes ferromagnetic.
文摘Background:Hard mineral and acid salt deposits that clump together in concentrated urine are known as kidney stones.A complicated chain of physicochemical events,including hyper saturation,nucleation,growth,aggrega-tion,and retention in the urinary tract,leads to urolithiasis,the third most prevalent urinary tract issue.Numerous traditional medications and therapies are less successful in treating urolithiasis and frequently cause recurrences.Objective:The present study is focused on evaluating the anti-urolithiasis activities of the polyherbal formulation prepared from Spinacia oleracea L.and Coriandrum sativum L.seeds.Methods:To evaluating the anti-urolithiasis activities of the polyherbal formulation prepared from S.oleracea and C.sativum seeds against oxalate crystals by employing an in vitro inhibition,aggregation,and nucleation assay,employing a spectrophotometer followed by microscopic observation,and further monitored by egg semiperme-able membrane model,using cystone as a standard drug.Results:In the present work,the alkaloids,glycosides,flavonoids,glycosides,phenols,saponins,steroids,tannins,terpenoids,and triterpenoids were found in the extracts of S.oleracea and C.sativum.The in vitro assays in the present study clearly indicated that all the mixture extracts readily prevented crystal nucleation,growth and ag-gregation.The aqueous extract of the mixture inhibited significant inhibitory potential against the crystallization process.Conclusion:It can be said that the phyto-constituents enriched homemade preparation possibly will be used as a medication for the management of kidney stones by dissolving the oxalate stone in the kidney.
文摘This exploration acquaints a momentous methodology with custom chatbot improvement that focuses on pro-ficiency close by viability.We accomplish this by joining three key innovations:LangChain,Retrieval Augmented Generation(RAG),and enormous language models(LLMs)tweaked with execution proficient strategies like LoRA and QLoRA.LangChain takes into consideration fastidious fitting of chatbots to explicit purposes,guaranteeing engaged and important collaborations with clients.RAG’s web scratching capacities engage these chatbots to get to a tremendous store of data,empowering them to give exhaustive and enlightening reactions to requests.This recovered data is then decisively woven into reaction age utilizing LLMs that have been calibrated with an emphasis on execution productivity.This combination approach offers a triple advantage:further developed viability,upgraded client experience,and extended admittance to data.Chatbots become proficient at taking care of client questions precisely and productively,while instructive and logically pertinent reactions make a more regular and drawing in cooperation for clients.At last,web scratching enables chatbots to address a more extensive assortment of requests by conceding them admittance to a more extensive information base.By digging into the complexities of execution proficient LLM calibrating and underlining the basic job of web-scratched information,this examination offers a critical commitment to propelling custom chatbot plan and execution.The subsequent chatbots feature the monstrous capability of these advancements in making enlightening,easy to understand,and effective conversational specialists,eventually changing the manner in which clients cooperate with chatbots.
文摘Nanocrystalline SnO<sub>2</sub> and CuO doped with SnO<sub>2</sub> were prepared by the co-precipitation method and characterized for different physiochemical properties and microbiological activity. The composition and morphological formation were characterized by XRD, HRTEM, Raman, FTIR, and UV-vis spectroscopy. The Powder X-ray analysis reveals that Sn4+ ions have substituted the Cu<sup>2+</sup> ions without changing the monoclinic structure of SnO<sub>2</sub> but the average particle size of the SnO<sub>2</sub> and CuO doped SnO<sub>2</sub> samples from 11 and 5 nm respectively. However, it exhibits an inhibiting strong bacterial growth against tested bacterial strains.
文摘To better elucidate epigenetic mechanisms that correlate with the dynamic gene expression program observed upon T-cell differentiation, we investigated the genomic landscape of histone modifications in naive and memory CD8＋ T cells. Using a ChlP-Seq approach coupled with global gene expression profiling, we generated genome-wide histone H3 lysine 4 （H3K4me3） and H3 lysine 27 （H3K27me3） trimethylation maps in naive, T memory stem cells, central memory cells, and effector memory cells in order to gain insight into how histone architecture is remodeled during T cell differentiation. We show that H3K4me3 histone modifications are associated with activation of genes, while H3K27me3 is negatively correlated with gene expression at canonical loci and enhancers associated with T-cell metabolism, effector function, and memory. Our results also reveal histone modifications and gene expression signatures that distinguish the recently identified T memory stem cells from other CD8＋ T-cell subsets. Taken together, our results suggest that CD8＋ lymphocytes undergo chromatin remodeling in a progressive fashion. These findings have major implications for our understanding of peripheral T-cell ontogeny and the formation of immunological memory.
文摘12-Tungstophosphoric heteropoly acid(TPA) with a Keggin structure was introduced into Al-incorporated mesoporous molecular sieves(AlSBA-15) by the incipient wetness method.The materials were characterized by X-ray diffraction,nitrogen adsorption,scanning electron microscopy,UV-Vis diffuse reflectance and Raman spectroscopy,which confirmed the Keggin and mesopore structure.Its catalytic activity was evaluated under solvent-free conditions in the liquid phase at 333-383 K for the propionylation of anisole with propionic anhydride.The catalysts used were AlSBA-15,10%,20%,and 40% TPA/AlSBA-15,and 20% TPA/MCM-48.In the propionylation of anisole with propionic anhydride,the substitution occurred predominantly at the para position.The 20% TPA/AlSBA-15 catalyst gave a total product yield of 48% with 98% selectivity towards 4-methoxypropiophenone.The regenerability of the catalyst was also studied and was found to be excellent.
文摘The booming electronics itself carries an impact on power quality. Superconducting Magnetic Energy Storage (SMES) is proposed to enhance power quality in three-phase systems under various loads. This paper aimed to compensate the voltage sags under various faults in the grid systems. The SMES is selected as an energy storage unit to improve the capability of voltage sag compensation. Optimized Dual Fuzzy Flow (ODFF) logic controller is designed to prevent the voltage sag time during excessive phase voltage variation. Hence the proposed controller strategy reduces the total harmonic distortion during various fault conditions. To regulate the contribution of active power, the least possible value is improved using ODFF. The depth of voltage sags compensation is achieved by the over modulation and an iterative loop is designed in the control block. While protecting sensitive loads from voltage disturbances, and sags initiated by the power system, the proposed configuration is advantageous for an industrial implementation. It is found that the proposed method can result in more than 50% additional sag support time when compared with the previous methods such as PI and PSO. Utilizing MATLAB Simulink, compensation of sag and minimization of THD is established, and the simulation tests are performed to evaluate the performance of the proposed control method.
文摘The effects of process variables in Simultaneous Saccharification and Fermentation (SSF) of wheat bran flour were studied in bulk fermentation using a coculture of Aspergillus niger - Kluveromyces marxianus. The effect of substrate density, pH, temperature, and enzyme concentration on wheat bran was predicted by designing experiments in which a single parameter is varied keeping other variables at a constant level. The above parameters were optimized for a batch culture in a fermentor. Optimal values for substrate concentration, pH, temperature, and enzyme concentration during processing were 200 g/l, 5.5, 65°C, and 7.5 IU, respectively. In pre-treatment experiments, the concentration of enzymes and the pre-treatment temperature are highly correlated. The influence of pH, temperature, and substrate density on ethanol production was investigated. Temperature pH was determined as optimal, 32°C and 5.5, respectively. After 48 hours of fermentation at optimum pH, a solution of wheat bran containing a maximum of 6% starch produces a maximum of 22.9 g/l ethanol.
文摘Electrical Capacitance Tomography (ECT) determines the dielectric permittivity of the interior object depending on the measurements of exterior capacitance. Generally, the electrodes are placed outside the PVC cylinder where the medium to be imaged is present;but in ECT using inter-electrode capacitance measurements can be achieved by placing inside of the dielectric medium. In the proposed ECT system, the ECT sensor is modeled using ANSYS software and the model is implemented in real ECT system. For each step of measurement, a stable AC signal is applied to a pair of electrodes that form a capacitor. The novel system is to measure the capacitance range variation in picofarad and the corresponding voltage ranges from 1 volt to 4 volts. The switching speed of all combinational electrodes is implemented using embedded system to achieve higher speed performance of AC ECT system which eliminates the drift and stray capacitance error. This is yielding the original image of unknown multiphase medium inside the electrodes using Lab VIEW. This paper investigates several advantages such as improved overall system performance;simple structure, avoids stray capacitance effect, reduces the drift problem and achieves high signal to noise ratio.
文摘This paper presents an intelligent controller employing Adaptive Neuro-Fuzzy Inference System (ANFIS) for extracting maximum power from the wind energy conversion system even during the change in the wind speed conditions with improved quality of power. The proposed induction generator with multilevel inverter along with intelligent controller based Maximum Power Point Tracking (MPPT) technique aims at integrating winds system with improved maximum power injection and minimum harmonic issues. The proposed method will improve the power quality which is delivered to the grid in terms of harmonic, and inject the maximum power to the grid. To validate the effectiveness of the proposed control strategy, ANFIS controller, Fuzzy Inference System (FIS) and without MPPT controller have been presented and tested using MATLAB/Simulink environment.
文摘Vedic mathematics is the system of mathematics followed in ancient Indian and it is applied in various mathematical branches. The word “Vedic” represents the storehouse of all knowledge. Because using Vedic Mathematics, the arithmetical problems are solved easily. The mathematical algorithms are formed from 16 sutras and 13 up-sutras. But there are some limitations in each sutra. Here, two sutras Nikhilam sutra and Karatsuba algorithm are considered. In this research paper, a novel algorithm for binary multiplication based on Vedic mathematics is designed using bit reduction technique. Though Nikhilam sutra is used for multiplication, it is not used in all applications. Because it is special in multiplication. The remainder is derived from this sutra by reducing the remainder bit size to N-2 bit. Here, the number of bits of the remainder is constantly maintained as N-2 bits. By using Karatsuba algorithm, the overall structure of the multiplier is designed. Unlike the conventional Karatsuba algorithm, the proposed algorithm requires only one multiplier with N-2 bits only. The speed of the proposed algorithm is improved with balancing the area and the power. Even though there is a deviation in lower order bits, this method shows larger difference in higher bit lengths.
