Palladium-catalyzed carboxylative Suzuki coupling reactions of benzyl chlorides with allyl pinacol-borate were successfully conducted in the absence of any extra ligand to produce β,γ-unsaturated esters in satisfact...Palladium-catalyzed carboxylative Suzuki coupling reactions of benzyl chlorides with allyl pinacol-borate were successfully conducted in the absence of any extra ligand to produce β,γ-unsaturated esters in satisfactory to good yields. The carboxylative Suzuki coupling reaction proceeded smooth-ly under mild conditions in the presence of palladium nanoparticles generated in situ through the formation of a π-benzylpalladium chloride intermediate.展开更多
Background: The skin serves as the first line of defense for the human body. Direct sunlight contains damaging radiations that can speed up the ageing process of the skin, resulting in wrinkles, leathery skin, dark pa...Background: The skin serves as the first line of defense for the human body. Direct sunlight contains damaging radiations that can speed up the ageing process of the skin, resulting in wrinkles, leathery skin, dark patches, and solar elastosis. Objectives: To evaluate the effect of multiple solar irradiation related factors at the protein level in human dermal fibroblast (HDF). The overall effect of individual solar irradiations such as Infrared A (IRA), blue light (BL), UVA, and UVB on HDF cells and the extent of molecular level aberrations to be assessed and compared against each. Methods: Label-free quantitative proteomics (MS/MS) approach has been adopted in this study to observe the protein level changes induced in the HDF cells through various exposures of full light sources. Following that, downstream insilico analysis has been carried out. Results: In this study, it is demonstrated all the four different solar irradiations significantly contribute to the molecular degeneration of skin cells through various mechanisms. This study confirms that BL down-regulates DNA repair proteins and the skin cells-HDF stimulate the histone proteins as a response mechanism to maintain the chromosomal integrity. Conclusions: The proteomics experiment carried out in the current study intends to support the future sun care products based on full light protection technology that can be custom designed to provide complete protection from the solar radiation. Similar technology could enhance the further investigations for deeper understanding of induction, mode of action, and prevention of skin damage from extensive solar irradiation.展开更多
Bismuth substituted cobalt nano ferrites with the chemical composition Co Bi<sub>x</sub> Fe<sub>2-x</sub> O<sub>4</sub> (x = 0.00, 0.05, 0.10, 0.15, 0.20 & 0.25) were prepared b...Bismuth substituted cobalt nano ferrites with the chemical composition Co Bi<sub>x</sub> Fe<sub>2-x</sub> O<sub>4</sub> (x = 0.00, 0.05, 0.10, 0.15, 0.20 & 0.25) were prepared by sol-gel combustion method. The phase identification of prepared samples is characterised by X-ray powder diffraction (XRD) method, which confirms the formation of a single phase fcc spinal structure. The mean crystallite sizes of all prepared samples were obtained within the range of 21 (±5) nm. Transmission Electron Microscopy (TEM) images also confirmed the crystallite size of all the synthesised samples was in nano range. With the effect of Bi<sup>3+</sup> ion substitution on spinal cobalt ferrite, the magnetic properties were investigated by using Vibration Sample Magnetometer (VSM). The obtained hysteresis (M-H) curves of all the samples were analysed under the applied magnetic field of range ± 10 K Oe at 300 K. The magnetic properties such as saturation magnetisation (M<sub>s</sub>), remnant magnetization (M<sub>r</sub>) and coercivity (H<sub>c</sub>) values are tabulated, which show a decrease in trend as the bismuth ion concentration increases. This is due to the addition of Bi<sup>3+</sup> ion in the place of Fe<sup>3+</sup> ion (octahedral site) and hence the Bi<sup>3+</sup>-Fe<sup>3+</sup> ion interaction predominates as compared with the Fe<sup>2+</sup>-Fe<sup>3+</sup> ion interaction. The data obtained from magnetic studies, the variation among the magnetic properties have been investigated for all the prepared samples.展开更多
An efficient and highly chemoselective heterogeneous catalyst system for quinoline hydrogenation was developed using unsupported nanoporous palladium(PdNPore).The PdNPore‐catalyzed chemoselective hydrogenation of qui...An efficient and highly chemoselective heterogeneous catalyst system for quinoline hydrogenation was developed using unsupported nanoporous palladium(PdNPore).The PdNPore‐catalyzed chemoselective hydrogenation of quinoline proceeded smoothly under mild reaction conditions(low H2 pressure and temperature)to yield 1,2,3,4‐tetrahydroquinolines(py‐THQs)in satisfactory to excellent yields.Various synthetically useful functional groups,such as halogen,hydroxyl,formyl,ethoxycarbonyl,and aminocarbonyl groups,remained intact during the quinoline hydrogenation.No palladium was leached from PdNPore during the hydrogenation reaction.Moreover,the catalyst was easily recovered and reused without any loss of catalytic activity.The results of kinetic,deuterium‐hydrogen exchange,and deuterium‐labeling experiments indicated that the present hydrogenation involves heterolytic H2 splitting on the surface of the catalyst.展开更多
Polypropylene (PP) is rated first as volume leader in the plastic sector. Its non-biodegradable property poses serious environmental problem in case of disposal. The catalytic cracking of PP was performed with various...Polypropylene (PP) is rated first as volume leader in the plastic sector. Its non-biodegradable property poses serious environmental problem in case of disposal. The catalytic cracking of PP was performed with various catalysts i.e. ZSM-5, Zeolite, RB and SPS. The cracking was observed under different feed to catalyst ratio i.e. 1:1 to 5:1. The fluidized bed reactor was fabricated with arrangement to measure the temperature ranging from 100<sup>。</sup>C to 800<sup>。</sup>C. The effective of feed to catalyst ratio was found 3:1 at a temperature range of 420<sup>。</sup>C - 510<sup>。</sup>C and catalyst ZSM-5 gives maximum liquid conversion of waste PP. Conversion of PP to liquid fuel will not only resolve the problem of disposal of waste polypropylene plastic but also give a value aided product.展开更多
As per the entail in wireless communication, the ever increasing switching speeds of digital devices pose significant challenges. Signal quality is more important for high speed products and the signal integrity ...As per the entail in wireless communication, the ever increasing switching speeds of digital devices pose significant challenges. Signal quality is more important for high speed products and the signal integrity must ensure reliable transmission where signal integrity is a measure of the quality of an electrical signal. A high speed differential signal will result in signal integrity issues such as crosstalk and radiated emission. One of the solutions to suppress radiated emission is defected ground pattern. This paper introduces a novel trident incurvature shaped defected ground structure to suppress radiated emission that arises in high speed differential signal. The proposed defected ground structure is implemented using Ansoft HFSS simulation tool and its performance is quantified in terms of scattering parameters. The proposed trident incurvature shaped defected ground pattern reduces near end coupling and far end coupling by more than 6 dB and 2 dB respectively. It also provides better return loss and insertion loss in the frequency range 1 - 6 GHz.展开更多
In the current electricity paradigm, the rapid elevation of demands in industrial sector and the process of restructuring are the main causes for the overuse of transmission systems. Hence, the evolution of novel tech...In the current electricity paradigm, the rapid elevation of demands in industrial sector and the process of restructuring are the main causes for the overuse of transmission systems. Hence, the evolution of novel technology is the ultimate need to avoid the damages in the available transmission systems. An appreciable volume of renewable energy sources is used to produce electric power, after the implementation of deregulation in power system. Even though, they are intended to improve the reliability of power system, the unpredictable outages of generators or transmission lines, an impulsive increase in demand and the sudden failures of vital equipment cause transmission congestion in one or some transmission lines. Generation rescheduling and load shedding can be used to alleviate congestion, but some cases require quite few improved methods. With the extensive application of Distributed Generation (DG), congestion management is also performed by the optimal placement of DGs. Therefore, this research employs a Line Flow Sensitivity Factor (LFSF) and Particle Swarm Optimization (PSO) for the determination of optimal location and size of multiple DG units, respectively. This proposed problem is formulated to minimize the total system losses and real power flow performance index. This approach is experimented in modified IEEE-30 bus test system. The results of N-1 contingency analysis with DG units prove the competence of this proposed approach, since the total numbers of congested lines get reduced from 15 to 2. Hence, the results show that the proposed approach is robust and simple in alleviating transmission congestion by the optimal placement and sizing of multiple DG units.展开更多
Peak Expiratory Flow Rate (PEFR) measures the airflow through the bronchi and thus the degree of obstruction in the airways. Exposure to high concentration of respirable suspended particulate matter (RSPM) decreases t...Peak Expiratory Flow Rate (PEFR) measures the airflow through the bronchi and thus the degree of obstruction in the airways. Exposure to high concentration of respirable suspended particulate matter (RSPM) decreases the PEFR and the decrease depends upon the exposure concentration of particles and exposure duration. The decrease in PEFR is found to be responsible for increase in blood pressure (BP). Relationship between increase in BP and reduction in PEFR is not exactly linear but it can be considered as liner. It is noticed that if PEFR is reduced to about 50% to 60% in that case sudden increase in BP is recorded and behaviour of BP rise has complex pattern. It is also an established fact that if PEFR is reduced more than 50%, this is treated as severe respiratory problem. There are many factors (i.e. smoking habits, medical treatment, physiology, etc.) which may govern the increase of BP in this condition. Estimated relationship is found as: ISBP = 0.213 + 0.263 IPEF, IDBP = 0.102 + 0.176 IPEF.展开更多
文摘Palladium-catalyzed carboxylative Suzuki coupling reactions of benzyl chlorides with allyl pinacol-borate were successfully conducted in the absence of any extra ligand to produce β,γ-unsaturated esters in satisfactory to good yields. The carboxylative Suzuki coupling reaction proceeded smooth-ly under mild conditions in the presence of palladium nanoparticles generated in situ through the formation of a π-benzylpalladium chloride intermediate.
文摘Background: The skin serves as the first line of defense for the human body. Direct sunlight contains damaging radiations that can speed up the ageing process of the skin, resulting in wrinkles, leathery skin, dark patches, and solar elastosis. Objectives: To evaluate the effect of multiple solar irradiation related factors at the protein level in human dermal fibroblast (HDF). The overall effect of individual solar irradiations such as Infrared A (IRA), blue light (BL), UVA, and UVB on HDF cells and the extent of molecular level aberrations to be assessed and compared against each. Methods: Label-free quantitative proteomics (MS/MS) approach has been adopted in this study to observe the protein level changes induced in the HDF cells through various exposures of full light sources. Following that, downstream insilico analysis has been carried out. Results: In this study, it is demonstrated all the four different solar irradiations significantly contribute to the molecular degeneration of skin cells through various mechanisms. This study confirms that BL down-regulates DNA repair proteins and the skin cells-HDF stimulate the histone proteins as a response mechanism to maintain the chromosomal integrity. Conclusions: The proteomics experiment carried out in the current study intends to support the future sun care products based on full light protection technology that can be custom designed to provide complete protection from the solar radiation. Similar technology could enhance the further investigations for deeper understanding of induction, mode of action, and prevention of skin damage from extensive solar irradiation.
文摘Bismuth substituted cobalt nano ferrites with the chemical composition Co Bi<sub>x</sub> Fe<sub>2-x</sub> O<sub>4</sub> (x = 0.00, 0.05, 0.10, 0.15, 0.20 & 0.25) were prepared by sol-gel combustion method. The phase identification of prepared samples is characterised by X-ray powder diffraction (XRD) method, which confirms the formation of a single phase fcc spinal structure. The mean crystallite sizes of all prepared samples were obtained within the range of 21 (±5) nm. Transmission Electron Microscopy (TEM) images also confirmed the crystallite size of all the synthesised samples was in nano range. With the effect of Bi<sup>3+</sup> ion substitution on spinal cobalt ferrite, the magnetic properties were investigated by using Vibration Sample Magnetometer (VSM). The obtained hysteresis (M-H) curves of all the samples were analysed under the applied magnetic field of range ± 10 K Oe at 300 K. The magnetic properties such as saturation magnetisation (M<sub>s</sub>), remnant magnetization (M<sub>r</sub>) and coercivity (H<sub>c</sub>) values are tabulated, which show a decrease in trend as the bismuth ion concentration increases. This is due to the addition of Bi<sup>3+</sup> ion in the place of Fe<sup>3+</sup> ion (octahedral site) and hence the Bi<sup>3+</sup>-Fe<sup>3+</sup> ion interaction predominates as compared with the Fe<sup>2+</sup>-Fe<sup>3+</sup> ion interaction. The data obtained from magnetic studies, the variation among the magnetic properties have been investigated for all the prepared samples.
基金supported by the National Natural Science Foundation of China(21573032,21773021)the Fundamental Research Funds for the Central Universities(DUT17ZD212)the International Scientific Partnership Program ISPP at King Saud University for funding this research work through ISPP#0048~~
文摘An efficient and highly chemoselective heterogeneous catalyst system for quinoline hydrogenation was developed using unsupported nanoporous palladium(PdNPore).The PdNPore‐catalyzed chemoselective hydrogenation of quinoline proceeded smoothly under mild reaction conditions(low H2 pressure and temperature)to yield 1,2,3,4‐tetrahydroquinolines(py‐THQs)in satisfactory to excellent yields.Various synthetically useful functional groups,such as halogen,hydroxyl,formyl,ethoxycarbonyl,and aminocarbonyl groups,remained intact during the quinoline hydrogenation.No palladium was leached from PdNPore during the hydrogenation reaction.Moreover,the catalyst was easily recovered and reused without any loss of catalytic activity.The results of kinetic,deuterium‐hydrogen exchange,and deuterium‐labeling experiments indicated that the present hydrogenation involves heterolytic H2 splitting on the surface of the catalyst.
文摘Polypropylene (PP) is rated first as volume leader in the plastic sector. Its non-biodegradable property poses serious environmental problem in case of disposal. The catalytic cracking of PP was performed with various catalysts i.e. ZSM-5, Zeolite, RB and SPS. The cracking was observed under different feed to catalyst ratio i.e. 1:1 to 5:1. The fluidized bed reactor was fabricated with arrangement to measure the temperature ranging from 100<sup>。</sup>C to 800<sup>。</sup>C. The effective of feed to catalyst ratio was found 3:1 at a temperature range of 420<sup>。</sup>C - 510<sup>。</sup>C and catalyst ZSM-5 gives maximum liquid conversion of waste PP. Conversion of PP to liquid fuel will not only resolve the problem of disposal of waste polypropylene plastic but also give a value aided product.
文摘As per the entail in wireless communication, the ever increasing switching speeds of digital devices pose significant challenges. Signal quality is more important for high speed products and the signal integrity must ensure reliable transmission where signal integrity is a measure of the quality of an electrical signal. A high speed differential signal will result in signal integrity issues such as crosstalk and radiated emission. One of the solutions to suppress radiated emission is defected ground pattern. This paper introduces a novel trident incurvature shaped defected ground structure to suppress radiated emission that arises in high speed differential signal. The proposed defected ground structure is implemented using Ansoft HFSS simulation tool and its performance is quantified in terms of scattering parameters. The proposed trident incurvature shaped defected ground pattern reduces near end coupling and far end coupling by more than 6 dB and 2 dB respectively. It also provides better return loss and insertion loss in the frequency range 1 - 6 GHz.
文摘In the current electricity paradigm, the rapid elevation of demands in industrial sector and the process of restructuring are the main causes for the overuse of transmission systems. Hence, the evolution of novel technology is the ultimate need to avoid the damages in the available transmission systems. An appreciable volume of renewable energy sources is used to produce electric power, after the implementation of deregulation in power system. Even though, they are intended to improve the reliability of power system, the unpredictable outages of generators or transmission lines, an impulsive increase in demand and the sudden failures of vital equipment cause transmission congestion in one or some transmission lines. Generation rescheduling and load shedding can be used to alleviate congestion, but some cases require quite few improved methods. With the extensive application of Distributed Generation (DG), congestion management is also performed by the optimal placement of DGs. Therefore, this research employs a Line Flow Sensitivity Factor (LFSF) and Particle Swarm Optimization (PSO) for the determination of optimal location and size of multiple DG units, respectively. This proposed problem is formulated to minimize the total system losses and real power flow performance index. This approach is experimented in modified IEEE-30 bus test system. The results of N-1 contingency analysis with DG units prove the competence of this proposed approach, since the total numbers of congested lines get reduced from 15 to 2. Hence, the results show that the proposed approach is robust and simple in alleviating transmission congestion by the optimal placement and sizing of multiple DG units.
文摘Peak Expiratory Flow Rate (PEFR) measures the airflow through the bronchi and thus the degree of obstruction in the airways. Exposure to high concentration of respirable suspended particulate matter (RSPM) decreases the PEFR and the decrease depends upon the exposure concentration of particles and exposure duration. The decrease in PEFR is found to be responsible for increase in blood pressure (BP). Relationship between increase in BP and reduction in PEFR is not exactly linear but it can be considered as liner. It is noticed that if PEFR is reduced to about 50% to 60% in that case sudden increase in BP is recorded and behaviour of BP rise has complex pattern. It is also an established fact that if PEFR is reduced more than 50%, this is treated as severe respiratory problem. There are many factors (i.e. smoking habits, medical treatment, physiology, etc.) which may govern the increase of BP in this condition. Estimated relationship is found as: ISBP = 0.213 + 0.263 IPEF, IDBP = 0.102 + 0.176 IPEF.
