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超低渗浅层油藏水平井钻井技术难点与突破 被引量:13
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作者 郝世彦 李伟峰 郭春芬 《中国石油勘探》 CAS 北大核心 2017年第5期15-20,共6页
针对延长东部油区低渗—超低渗储层埋深浅,地层压力低,常规井开发井多、低产、低效问题日益突出的难题,以及水平井开发受低温、低压、埋深因素干扰,建井难度高的问题,开展了浅层—超浅层大位移水平井钻完井配套技术研究与应用。创新水... 针对延长东部油区低渗—超低渗储层埋深浅,地层压力低,常规井开发井多、低产、低效问题日益突出的难题,以及水平井开发受低温、低压、埋深因素干扰,建井难度高的问题,开展了浅层—超浅层大位移水平井钻完井配套技术研究与应用。创新水平井钻井压裂一体化理念,针对压裂后易形成水平缝的低压浅层油藏,采用"弓形"水平井设计方法,配合浅层缝网压裂技术,比常规水平井的水平段提高至少30%的动用水平,实现了低垂向应力储层的高效动用;采取井眼轨道与井身剖面协同优化设计,采用低成本钻井加压技术,配合下套管优化技术,提高钻柱轴向压力及传输效率,实现了多口高难度水平井的成功建井。为提高延长东部浅层超低渗油藏开发效果,提供了坚实的技术支撑,具有较高的经济效益和社会效益。 展开更多
关键词 超浅层大位移水平井 浅层油藏 低渗透油藏 鄂尔多斯盆地
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Pressure-Tuned Intrinsic Anomalous Hall Conductivity in Kagome Magnets RV_(6)Sn_(6)(R=Gd,Tb)
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作者 孔祥明 陶咨成 +8 位作者 张蕊 夏威 陈旭 裴翠颖 应天平 齐彦鹏 郭艳峰 杨小帆 李世燕 《Chinese Physics Letters》 SCIE EI CAS CSCD 2024年第4期139-151,共13页
Exploration of exotic phenomena in magnetic topological systems is at the frontier of condensed matter physics,holding a significant promise for applications in topological spintronics.However,complex magnetic structu... Exploration of exotic phenomena in magnetic topological systems is at the frontier of condensed matter physics,holding a significant promise for applications in topological spintronics.However,complex magnetic structures carrying nontrivial topological properties hinder its progresses.Here,we investigate the pressure effect on the novel topological kagome magnets GdV_(6)Sn_(6) and TbV_(6)Sn_(6) to dig out the interplay between magnetic Gd/Tb layers and nonmagnetic V-based kagome sublattice.The pressure-tuned magnetic transition temperature Tm in both the compounds exhibit a turning point at the critical pressure P_(c),accompanied with a sign reversal in anomalous Hall effect(AHE).The separation of intrinsic and extrinsic contributions using the Tian-Ye-Jin scaling model suggests that the intrinsic mechanism originating from the electronic Berry curvature holds the priority in the competition with extrinsic mechanism in AHE.The above-mentioned findings can be attributed to the combined effect of pressure-tuned band topology and magnetic interaction in segregated layers.Our results provide a practical route to design and manipulate the intrinsic AHE in magnetic topological materials. 展开更多
关键词 holds FRONTIER hinder
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Ultralow-temperature heat transport study of noncentrosymmetric superconductor CaPtAs
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作者 万一民 程二建 +8 位作者 陈宇鑫 赵成成 涂成鹏 戴东喆 杨小帆 辛路 谢武 袁辉球 李世燕 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第12期158-161,共4页
The noncentrosymmetric superconductor CaPtAs with time-reversal symmetry breaking in its superconducting state was previously proposed to host nodal superconductivity.Here,by employing ultralow-temperature thermal con... The noncentrosymmetric superconductor CaPtAs with time-reversal symmetry breaking in its superconducting state was previously proposed to host nodal superconductivity.Here,by employing ultralow-temperature thermal conductivity measurement on CaPtAs single crystal,we study its superconducting gap structure.A negligible residual linear term of thermal conductivity(κ_(0)/T)in zero magnetic field and the field dependence ofκ_(0)/T indicate that CaPtAs has multiple superconducting gaps with a dominant s-wave component.This is consistent with recent nuclear quadrupole resonance measurements on CaPtAs.Our work puts a strong constraint on the theories to describe the superconducting pairing symmetry of CaPtAs. 展开更多
关键词 noncentrosymmetric superconductor thermal conductivity superconducting gap structure
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TP53INP1高表达在砷剂杀伤肺腺癌细胞中的增敏作用 被引量:1
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作者 罗擎英 谷仕艳 +1 位作者 李洋 张遵真 《卫生研究》 CAS CSCD 北大核心 2017年第1期120-125,共6页
目的构建TP53INP1高表达的肺腺癌A549细胞,初步研究提高TP53INP1的表达能否提高砷剂对肺腺癌细胞的杀伤作用。方法构建TP53INP1重组真核表达质粒,以慢病毒为载体将其转染到A549细胞,建立稳定高表达TP53INP1基因的A549-TP53INP1细胞株,... 目的构建TP53INP1高表达的肺腺癌A549细胞,初步研究提高TP53INP1的表达能否提高砷剂对肺腺癌细胞的杀伤作用。方法构建TP53INP1重组真核表达质粒,以慢病毒为载体将其转染到A549细胞,建立稳定高表达TP53INP1基因的A549-TP53INP1细胞株,以流式细胞术和MTT实验检测As_2O_3处理后A549-TP53INP1细胞的凋亡和存活率。结果成功构建稳定A549-TP53INP1细胞株。流式细胞术结果显示,相同剂量As2O3作用下(5~40μmol/L),A549-TP53INP1细胞凋亡率[(15.6±3.5)%]显著高于A549细胞[(10.0±2.5)%](P<0.05)。MTT实验显示,As_2O_3处理后A549-TP53INP1细胞的IC50值[(44.64±6.84)μmol/L]显著低于A549细胞[(54.25±6.13)μmol/L](P<0.05)。结论 TP53INP1高表达可增加砷剂对肺腺癌细胞的杀灭作用,提示TP53INP1可作为砷剂治疗肺癌的增敏靶点。 展开更多
关键词 TP53INP1 AS2O3 凋亡 敏感性 肺癌
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