The nodal stage of colorectal cancer is based on the number of positive nodes.It is inevitably affected by the number of removed lymph nodes,but lymph node ratio can be unaffected.We investigated the value of lymph no...The nodal stage of colorectal cancer is based on the number of positive nodes.It is inevitably affected by the number of removed lymph nodes,but lymph node ratio can be unaffected.We investigated the value of lymph node ratio in stage Ⅲ colorectal cancer in this study.The clinicopathologic factors and follow-up data of 145 cases of stage Ⅲ colorectal cancer between January 1998 and December 2008 were analyzed retrospectively.The Pearson and Spearman correlation analyses were used to determine the correlation coefficient,the Kaplan-Meier method was used to analyze survival,and the Cox proportional hazard regression model was used for multivariate analysis in forward stepwise regression.We found that lymph node ratio was not correlated with the number of removed lymph nodes(r =-0.154,P = 0.065),but it was positively correlated with the number of positive lymph nodes(r = 0.739,P < 0.001) and N stage(r = 0.695,P < 0.001).Kaplan-Meier survival analysis revealed that tumor configuration,intestinal obstruction,serum carcinoembryonic antigen(CEA) concentration,T stage,N stage,and lymph node ratio were associated with disease-free survival of patients with stage Ⅲ colorectal cancer(P < 0.05).Multivariate analysis showed that serum CEA concentration,T stage,and lymph node ratio were prognostic factors for disease-free survival(P < 0.05),whereas N stage failed to achieve significance(P = 0.664).We confirmed that lymph node ratio was a prognostic factor in stage Ⅲ colorectal cancer and had a better prognostic value than did N stage.展开更多
BACKGROUND An extra tooth in the normal tooth sequence in any region of the dental arch is regarded as a supernumerary tooth(SNT).Due to the large variation in location and morphology,the extraction of impacted SNTs i...BACKGROUND An extra tooth in the normal tooth sequence in any region of the dental arch is regarded as a supernumerary tooth(SNT).Due to the large variation in location and morphology,the extraction of impacted SNTs is an extensive and complex procedure with high risks of several complications.This report presents a rare case of seven impacted SNTs in the bilateral upper and lower arch that were successfully extracted with the use of digital positioning guide plates.CASE SUMMARY In January 2022,a 21-year-old male was referred to our department with a chief complaint of pain in relation to tooth#36.Clinical examination showed a deep carious lesion with pulpal involvement in tooth#36 and lingual swelling of the bilateral mandibular posterior area.Radiographic examination revealed seven deeply impacted SNTs in the bilateral posterior area and bilateral impacted mandibular third molars.Based on these findings,the patient was diagnosed with bilateral,multiple impacted SNTs and tooth#36 chronic pulpitis.A root canal treatment and an all-ceramic crown restoration for tooth#36 were performed.An individualized digital positioning guide plate was designed by computer-aided design/computer-aided manufacturing technology and cone-beam computed tomography for extraction of the impacted SNTs.During the operation,the digital positioning guide plate allowed rapid positioning and exposure of the SNTs while avoiding adjacent important anatomical structures.At 3-month follow-up,regeneration of bone and soft tissues was visible.CONCLUSION The application of digital positioning guide plates is useful for the individualized and minimalized extraction of impacted supernumerary teeth.展开更多
To overcome the aggregation of nanocrystals in a blend of inorganic material with conjugated polymers to prepare photovoltaic material, we used a co-solvent blend of CHCl3 with MeOH at a certain volume fraction to dis...To overcome the aggregation of nanocrystals in a blend of inorganic material with conjugated polymers to prepare photovoltaic material, we used a co-solvent blend of CHCl3 with MeOH at a certain volume fraction to disperse inorganic nanocrystals. The results show that when the volume fraction of MeOH is 50%, ZnO nanocrystals with an average diameter of 30 nm disperse well in the co-solvent solution. Its application in photovoltaic material was investigated in this work, and the photoluminescence（PL） spectra show that when ZnO was 50%（volume fraction） in solution and 25%（volume fraction） in film, the fluorescence quenching reached the maximum values 83.34% and 64.4%, respectively, indicating that electron could transfer from conjugated polymer to electron-acceptor ZnO effectively.展开更多
文摘The nodal stage of colorectal cancer is based on the number of positive nodes.It is inevitably affected by the number of removed lymph nodes,but lymph node ratio can be unaffected.We investigated the value of lymph node ratio in stage Ⅲ colorectal cancer in this study.The clinicopathologic factors and follow-up data of 145 cases of stage Ⅲ colorectal cancer between January 1998 and December 2008 were analyzed retrospectively.The Pearson and Spearman correlation analyses were used to determine the correlation coefficient,the Kaplan-Meier method was used to analyze survival,and the Cox proportional hazard regression model was used for multivariate analysis in forward stepwise regression.We found that lymph node ratio was not correlated with the number of removed lymph nodes(r =-0.154,P = 0.065),but it was positively correlated with the number of positive lymph nodes(r = 0.739,P < 0.001) and N stage(r = 0.695,P < 0.001).Kaplan-Meier survival analysis revealed that tumor configuration,intestinal obstruction,serum carcinoembryonic antigen(CEA) concentration,T stage,N stage,and lymph node ratio were associated with disease-free survival of patients with stage Ⅲ colorectal cancer(P < 0.05).Multivariate analysis showed that serum CEA concentration,T stage,and lymph node ratio were prognostic factors for disease-free survival(P < 0.05),whereas N stage failed to achieve significance(P = 0.664).We confirmed that lymph node ratio was a prognostic factor in stage Ⅲ colorectal cancer and had a better prognostic value than did N stage.
基金Supported by National Natural Science Foundation of China,No.81970972Applied Basic Research Projects of the 920th Hospital of Joint Logistics Support Force,No.2020YGB06。
文摘BACKGROUND An extra tooth in the normal tooth sequence in any region of the dental arch is regarded as a supernumerary tooth(SNT).Due to the large variation in location and morphology,the extraction of impacted SNTs is an extensive and complex procedure with high risks of several complications.This report presents a rare case of seven impacted SNTs in the bilateral upper and lower arch that were successfully extracted with the use of digital positioning guide plates.CASE SUMMARY In January 2022,a 21-year-old male was referred to our department with a chief complaint of pain in relation to tooth#36.Clinical examination showed a deep carious lesion with pulpal involvement in tooth#36 and lingual swelling of the bilateral mandibular posterior area.Radiographic examination revealed seven deeply impacted SNTs in the bilateral posterior area and bilateral impacted mandibular third molars.Based on these findings,the patient was diagnosed with bilateral,multiple impacted SNTs and tooth#36 chronic pulpitis.A root canal treatment and an all-ceramic crown restoration for tooth#36 were performed.An individualized digital positioning guide plate was designed by computer-aided design/computer-aided manufacturing technology and cone-beam computed tomography for extraction of the impacted SNTs.During the operation,the digital positioning guide plate allowed rapid positioning and exposure of the SNTs while avoiding adjacent important anatomical structures.At 3-month follow-up,regeneration of bone and soft tissues was visible.CONCLUSION The application of digital positioning guide plates is useful for the individualized and minimalized extraction of impacted supernumerary teeth.
基金Supported by the National Program on Key Basic Research Project of China(No.2010CB635111)the Doctorate Foundation of Northwestern Polytechnical University,China(No.CX201118)
文摘To overcome the aggregation of nanocrystals in a blend of inorganic material with conjugated polymers to prepare photovoltaic material, we used a co-solvent blend of CHCl3 with MeOH at a certain volume fraction to disperse inorganic nanocrystals. The results show that when the volume fraction of MeOH is 50%, ZnO nanocrystals with an average diameter of 30 nm disperse well in the co-solvent solution. Its application in photovoltaic material was investigated in this work, and the photoluminescence（PL） spectra show that when ZnO was 50%（volume fraction） in solution and 25%（volume fraction） in film, the fluorescence quenching reached the maximum values 83.34% and 64.4%, respectively, indicating that electron could transfer from conjugated polymer to electron-acceptor ZnO effectively.
