Background The safety of percutaneous coronary intervention （PCI） for chronic total occlusion （CTO） lesions in remote hospitals without surgical facilities remains unknown. This study aimed to evaluate three-year ...Background The safety of percutaneous coronary intervention （PCI） for chronic total occlusion （CTO） lesions in remote hospitals without surgical facilities remains unknown. This study aimed to evaluate three-year outcomes after CTO for PCI in ten centers around China where no on-site coronary artery bypass grafting （CABG） support was available. Methods A total of 152 patients from 10 Chinese hospitals without on-site surgical facilities were prospectively studied. Intra-procedural and in-hospital events were assessed. Angiographic follow-up was indexed eight months after the initial procedure. Clinical follow-up was extended to three years. The primary outcome was the rate of major adverse cardiac events （MACE）, defined as cardiac death, myocardial infarction and target-vessel revascularization （TVR）. Results The incidence of CTO was 7.9% in patients who underwent PCI, Successful recanalization was achieved in 132 patients （86.8%）. Compared with patients in the PCI success group, patients with PCI procedural failure had longer lesion lengths （（42.32±22.08） mm vs （27.61±22.85） mm, P=0.023）, a higher rate of perforation （25.0% vs 0, P=0.014）, and a greater need for pericardial puncture. There were significant differences in MACE in-hospital and at one year and three years between the failure （10.0%, 30.0% and 35.0%） and the success （3.0%, 12.1% and 14.4%） groups （P=0.037, 0.034 and 0.040, respectively）. These led to a significant decrease in the MACE-free survival rate at one and three years in the failure group, compared with the success group （P=0.031 and 0.023, respectively）. Stump was the only predictor of recanalization success （HR 0.158, 95% Cl 0.041-0.612, P=0.008）, whereas procedural failure （OR 13.023, 95% CI 6.67-13.69, P=0.002）, incomplete revascularization （OR 9.71, 95% CI 2.93-5.59, P=0.005）, and total stent length （OR 6.02, 95% Cl 1.55-11.93, P=0.027） were three independent predictors of MACE. Conclusions PCI for CTO was unsafe 展开更多
Building a cloud geodatabase for a sponge city is crucial to integrate the geospatial information dispersed in various departments for multi-user high concurrent access and retrieval,high scalability and availability,...Building a cloud geodatabase for a sponge city is crucial to integrate the geospatial information dispersed in various departments for multi-user high concurrent access and retrieval,high scalability and availability,efficient storage and management.In this study,Hadoop distributed computing framework,including Hadoop distributed file system and MapReduce(mapper and reducer),is firstly designed with a parallel computing framework to process massive spatial data.Then,access control with a series of standard application programming interfaces for different functions is designed,including spatial data storage layer,cloud geodatabase access layer,spatial data access layer and spatial data analysis layer.Subsequently,a retrieval model is designed,including direct addressing via file name,three-level concurrent retrieval and block data retrieval strategies.Main functions are realised,including real-time concurrent access,high-performance computing,communication,massive data storage,efficient retrieval and scheduling decisions on the multi-scale,multi-source and massive spatial data.Finally,the performance of Hadoop cloud geodatabases is validated and compared with that of the Oracle database.The cloud geodatabase for the sponge city can avoid redundant configuration of personnel,hardware and software,support the data transfer,model debugging and application development,and provide accurate,real-time,virtual,intelligent,reliable,elastically scalable,dynamic and on-demand cloud services of the basic and thematic geographic information for the construction and management of the sponge city.展开更多
In this paper, we demonstrate that the eco-industrial network equilibrium model of link flow version previously introduced can be reformulated as a transportation network equilibrium problem of path flow version. Then...In this paper, we demonstrate that the eco-industrial network equilibrium model of link flow version previously introduced can be reformulated as a transportation network equilibrium problem of path flow version. Then, some methodological tools mainly applied in the field of transportation science can be used to discuss the eco-industrial chain network problem. What the highlighted contribution lies in is that the paper not only expands theory of supply chain model with reducing path flow but also generalizes the traditional transportation network equilibrium problem by new applications.展开更多
文摘Background The safety of percutaneous coronary intervention （PCI） for chronic total occlusion （CTO） lesions in remote hospitals without surgical facilities remains unknown. This study aimed to evaluate three-year outcomes after CTO for PCI in ten centers around China where no on-site coronary artery bypass grafting （CABG） support was available. Methods A total of 152 patients from 10 Chinese hospitals without on-site surgical facilities were prospectively studied. Intra-procedural and in-hospital events were assessed. Angiographic follow-up was indexed eight months after the initial procedure. Clinical follow-up was extended to three years. The primary outcome was the rate of major adverse cardiac events （MACE）, defined as cardiac death, myocardial infarction and target-vessel revascularization （TVR）. Results The incidence of CTO was 7.9% in patients who underwent PCI, Successful recanalization was achieved in 132 patients （86.8%）. Compared with patients in the PCI success group, patients with PCI procedural failure had longer lesion lengths （（42.32±22.08） mm vs （27.61±22.85） mm, P=0.023）, a higher rate of perforation （25.0% vs 0, P=0.014）, and a greater need for pericardial puncture. There were significant differences in MACE in-hospital and at one year and three years between the failure （10.0%, 30.0% and 35.0%） and the success （3.0%, 12.1% and 14.4%） groups （P=0.037, 0.034 and 0.040, respectively）. These led to a significant decrease in the MACE-free survival rate at one and three years in the failure group, compared with the success group （P=0.031 and 0.023, respectively）. Stump was the only predictor of recanalization success （HR 0.158, 95% Cl 0.041-0.612, P=0.008）, whereas procedural failure （OR 13.023, 95% CI 6.67-13.69, P=0.002）, incomplete revascularization （OR 9.71, 95% CI 2.93-5.59, P=0.005）, and total stent length （OR 6.02, 95% Cl 1.55-11.93, P=0.027） were three independent predictors of MACE. Conclusions PCI for CTO was unsafe
基金Project(NZ1628)supported by the Natural Science Foundation of Ningxia,China
文摘Building a cloud geodatabase for a sponge city is crucial to integrate the geospatial information dispersed in various departments for multi-user high concurrent access and retrieval,high scalability and availability,efficient storage and management.In this study,Hadoop distributed computing framework,including Hadoop distributed file system and MapReduce(mapper and reducer),is firstly designed with a parallel computing framework to process massive spatial data.Then,access control with a series of standard application programming interfaces for different functions is designed,including spatial data storage layer,cloud geodatabase access layer,spatial data access layer and spatial data analysis layer.Subsequently,a retrieval model is designed,including direct addressing via file name,three-level concurrent retrieval and block data retrieval strategies.Main functions are realised,including real-time concurrent access,high-performance computing,communication,massive data storage,efficient retrieval and scheduling decisions on the multi-scale,multi-source and massive spatial data.Finally,the performance of Hadoop cloud geodatabases is validated and compared with that of the Oracle database.The cloud geodatabase for the sponge city can avoid redundant configuration of personnel,hardware and software,support the data transfer,model debugging and application development,and provide accurate,real-time,virtual,intelligent,reliable,elastically scalable,dynamic and on-demand cloud services of the basic and thematic geographic information for the construction and management of the sponge city.
基金Sponsored by the Fundamental Research Funds for the Central Universitiesthe Research Funds of Renmin University of China(Grant No.13XNH169)
文摘In this paper, we demonstrate that the eco-industrial network equilibrium model of link flow version previously introduced can be reformulated as a transportation network equilibrium problem of path flow version. Then, some methodological tools mainly applied in the field of transportation science can be used to discuss the eco-industrial chain network problem. What the highlighted contribution lies in is that the paper not only expands theory of supply chain model with reducing path flow but also generalizes the traditional transportation network equilibrium problem by new applications.
