Objective： To determine the clinical serum levels of carcinoembryonic antigen （CEA） and carbohydrate antigen 19-9 （CA19-9）, individually and in combination, for the diagnosis of 50 healthy subjects and 150 cases ...Objective： To determine the clinical serum levels of carcinoembryonic antigen （CEA） and carbohydrate antigen 19-9 （CA19-9）, individually and in combination, for the diagnosis of 50 healthy subjects and 150 cases of esophageal, gastric, and colon cancers. Methods： The sensitivities of the two markers were compared individually and in combination, with specificity set at 100%. Receiver operating characteristic （ROC） curves were plotted. Results： Serum CEA levels were significantly higher in cancer patients than in the control group. The sensitivity of CEA was determined： in esophageal cancer, sensitivity=28%, negative predictive value （NPV）=61.72%, and AUC=0.742 （SE=0.05）, with a significance level of P〈0.0001; in gastric cancer, sensitivity=30%, NPV=58.82%, and AUC=0.734 （SE=0.0S）, with a significance level of P〈0.0001; in colon cancer, sensitivity=74%, NPV=79.36%, and AUC=0.856 （SE=0.04）, with a significance level of P〈0.0001. The sensitivity of CA19-9 was also evaluated： in esophageal cancer, sensitivity=18%, NPV=54.94%, and AUC=0.573 （SE=0.05）, with a significance level of P=0.2054. In gastric cancer, sensitivity=42%, NPV=63.29%, and AUC=0.679 （SE=0.05）, with a significance level of P〈0.0011. In colon cancer, sensitivity=26%, NPV=57.47%, and AUC=0.S80 （SE=0.05）, with a significance level ofP=0.1670. The following were the sensitivities of CEA/CA19-9 combined： in esophageal cancer, sensitivity=42%, NPV=63.29%, SE=0.078 （95% CI： 0.0159-0.322）; gastric cancer, sensitivity=S8%, NPV=70.42%, SE=0.072 （9$% CI： -0.0866-0.198）; and colon cancer, sensitivity=72%, NPV=78.12%, SE=0.070 （9S% CI： 0.137-0.415）. Conclusion： CEA exhibited the highest sensitivity for colon cancer, and CA19-9 exhibited the highest sensitivity for gastric cancer. Combined analysis indicated an increase in diagnostic sensitivity in esophageal and gastric cancer compared with that in colon cancer.展开更多
Treatment of reverse oblique trochanteric femoral fractures poses a lot of challenges. There have been proponents of intramedullary devices as well as extramedullary devices. We present the results of proximal femoral...Treatment of reverse oblique trochanteric femoral fractures poses a lot of challenges. There have been proponents of intramedullary devices as well as extramedullary devices. We present the results of proximal femoral nailing surgery performed for reverse obliquity intertrochanteric fractures using two proximal lag screws and a nail of 250 mm. There is prospective study of fifty three patients with AO/OTA 31 A-A3 fractures being treated by proximal femoral nailing in our institute after seeking approval from the Hospital ethics board. The quality of the reduction, the operative time, complications and the functional status of the patients were the parameters on which the results were evaluated. The mean Harris hip score was 76.66 (range 70 - 93) and the mean Barthel activity score was 16.21 (range 12 - 20). The average surgical time was 50 minutes and the mean consolidation time was 11.5 weeks. Intramedullary nailing with proximal femoral nails seems to be a good option in the treatment of reverse obliquity intertrochanteric fractures as against the various existing options available for the management.展开更多
Getting the trajectory of the proximal femoral nail in the right direction is essential to achieve a good result in the technically demanding surgery of proximal femoral fracture. Either an inappropriate starting poin...Getting the trajectory of the proximal femoral nail in the right direction is essential to achieve a good result in the technically demanding surgery of proximal femoral fracture. Either an inappropriate starting point or a failure to match the chosen implant’s lateral entry angle may cause coronal plane deformity after trochanteric entry nailing. The lateral view is the critical view for localization of the proper starting point. For the right execution of the surgery, getting the trajectoy right is fully under the control of the surgeon and should always be attempted.展开更多
A multiple power quality(MPQ)disturbance has two or more power quality(PQ)disturbances superimposed on a voltage signal.A compact and robust technique is required to identify and classify the MPQ disturbances.This man...A multiple power quality(MPQ)disturbance has two or more power quality(PQ)disturbances superimposed on a voltage signal.A compact and robust technique is required to identify and classify the MPQ disturbances.This manuscript investigated a hybrid algorithm which is designed using parallel processing of voltage with multiple power quality(MPQ)disturbance using stockwell transform(ST)and hilbert transform(HT).This will reduce the computational time to identify theMPQdisturbances,whichmakes the algorithm fast.A MPQ identification index(IPI)is computed using statistical features extracted from the voltage signal using the ST and HT.IPI has different patterns for various types of MPQ disturbances which effectively identify the MPQ disturbances.A MPQ time location index(IPL)is computed using the features extracted from the voltage signal using ST and HT.IPL effectively identifies the initiation and end of PQ disturbances and thereby locates the MPQ events with respect to time.Classification of MPQ disturbances is performed using decision rules in both the noise-free and noisy environments with a 20 dB noise to signal ratio(SNR).The performance of the proposed hybrid algorithm using ST and HT with rule-based decision tree(RBDT)is better compared to the ST and RBDT techniques in terms of accuracy of classification of MPQ disturbances.MATLAB software is used to perform the study.展开更多
The COVID-19 pandemic has created a major challenge for countries all over the world and has placed tremendous pressure on their public health care services.An early diagnosis of COVID-19 may reduce the impact of the ...The COVID-19 pandemic has created a major challenge for countries all over the world and has placed tremendous pressure on their public health care services.An early diagnosis of COVID-19 may reduce the impact of the coronavirus.To achieve this objective,modern computation methods,such as deep learning,may be applied.In this study,a computational model involving deep learning and biogeography-based optimization(BBO)for early detection and management of COVID-19 is introduced.Specifically,BBO is used for the layer selection process in the proposed convolutional neural network(CNN).The computational model accepts images,such as CT scans,X-rays,positron emission tomography,lung ultrasound,and magnetic resonance imaging,as inputs.In the comparative analysis,the proposed deep learning model CNNis compared with other existingmodels,namely,VGG16,InceptionV3,ResNet50,and MobileNet.In the fitness function formation,classification accuracy is considered to enhance the prediction capability of the proposed model.Experimental results demonstrate that the proposed model outperforms InceptionV3 and ResNet50.展开更多
The objective of this study was to develop novel transanasl microemulsion containing carbamazepine for treatment of epilepsy.Oleic acid was selected as oil while Tween 80 and propylene glycol were selected as surfacta...The objective of this study was to develop novel transanasl microemulsion containing carbamazepine for treatment of epilepsy.Oleic acid was selected as oil while Tween 80 and propylene glycol were selected as surfactant and cosurfactant respectively based on solubility results.Optimized ratio of Tween 80:propylene glycol was selected after developing pseudoternary phase diagrams for different ratio and microemulsions were prepared.The prepared microemulsions were evaluated for globule size,viscosity,pH,conductivity and%transmittance.Exvivo diffusion study for optimized microemulsion was performed through sheep nasal mucosa wherein diffusion flux and permeability coefficients were determined.Further pharmacodynamic performance was evaluated in rats by electrically induced seizures.It was found that optimized microemulsion was stable and transparent with average globule size of 190 nm and diffusion flux of 75.77 mg cm2 min1 and showed no toxicity during histopathological evaluation on sheep nasal mucosa.Pharmacodynamic evaluation also indicated lesser intensity of seizures in rats treated with optimized formulation in comparison to rats treated with oral carbamazepine microemulsion and nasal carbamazepine solution which suggested carbamazepine transnasal delivery system as an effective alternate therapy for treatment of epilepsy.展开更多
Obstructive jaundice in the setting of a hilar mass raises strong suspicion of a cholangiocarcinoma,with diagnosis usually made on imaging.Jaundice,when present in patients with hepatocellular carcinoma,is mostly rela...Obstructive jaundice in the setting of a hilar mass raises strong suspicion of a cholangiocarcinoma,with diagnosis usually made on imaging.Jaundice,when present in patients with hepatocellular carcinoma,is mostly related to underlying liver disease(i.e.cirrhosis)and only rarely to diffuse tumor infiltration of liver parenchyma or hilar invasion.We report here the good outcome of a 67 year-old patient who presented with obstructive jaundice,underwent surgery and was given a diagnosis of hepatocellular carcinoma,which was made only at histopathological examination of resected specimen.展开更多
A case of 16 yrs male patient with parosteal lipoma affecting the lower metaphyseal end of the left femur is presented. Clinical suspicion, plain radiographs, CT (Plain and 3 D) as well as MRI suggested a diagnosis of...A case of 16 yrs male patient with parosteal lipoma affecting the lower metaphyseal end of the left femur is presented. Clinical suspicion, plain radiographs, CT (Plain and 3 D) as well as MRI suggested a diagnosis of parosteal lipoma. Lipomas may be defined as benign lesions of mature adipose tissue without evidence of cellular atypia [1]. Lipomas are the most common soft tissue lesions and surprisingly are among the rarest bone neoplasias. The most frequent complaints are a tumoral convexity presenting as a visible or palpable mass or a mild-intensity, dull pain. The parosteal type is a rare tumor accounting for 0.3% of all lipomas [2] and is usually asymptomatic. It is seen commonly affecting adults aged over 40 [3]. The present article describes a rare case of parosteal lipoma located in the femur, with extensive hyperostosis visible on plain xray and confirmed by imaging studies (CT and MRI). Unlike the parosteal lipomas reported in adults over 40 yrs in this case it presented in a much younger age group.展开更多
This study introduces a two-level strategy for efficient execution of multiple sequence alignment (MSA) of complex heterogeneous sequences. The two levels of the proposed technique are comprised of: designing the disc...This study introduces a two-level strategy for efficient execution of multiple sequence alignment (MSA) of complex heterogeneous sequences. The two levels of the proposed technique are comprised of: designing the discrete firefly algorithm (DFFA) for the formation and implementation of makespan minimisation on parallel machines, followed by performing Ctrie-based caching for pairwise alignment to reduce the load on the data servers for handling multiple queries. The proposed strategy addresses a multi-client problem that aims to acquire the full advantage of the computational power of parallel connected machines. Further, it is shown that the inclusion of Ctrie as caching mechanism successively improves the performance of the system with accretion in several sequences. Performance of proposed DFFA is also compared with discrete versions of four swarm intelligence based algorithms at the criteria of makespan minimisation and the rate of convergence on two kinds of complex and diverse datasets. The work is unique in this sense: it is the first swarm-intelligence-based implementation for the addressed problem;it is so far the first approach for Ctrie based caching of the MSA on the scheduled parallel machines;hybridisation of DFFA with Ctrie for caching the MSA results is also a novel implementation.展开更多
Heat flux characteristics are critical to good quality welding obtained in the important engineering alloy A12024- T3 by the friction stir welding （FSW） process. In the present study, thermocouples in three differen...Heat flux characteristics are critical to good quality welding obtained in the important engineering alloy A12024- T3 by the friction stir welding （FSW） process. In the present study, thermocouples in three different configurations were amxed on the welding samples to measure the temperatures： in the first configuration, four thermocouples were placed at equivalent positions along one side of the welding direction; the second configuration involved two equivalent thermocouple locations on either side of the welding path; while the third configuration had all the thermocouples on one side of the layout but with unequal gaps from the welding line. A three-dimensional, non-linear ANSYS computational model, based on an approach applied to A12024-T3 for the first time, was used to simulate the welding temperature profiles obtained experimentally. The experimental thermal profiles on the whole were found to be in agreement with those calculated by the ANSYS model. The broad agreement between the two kinds of profiles validates the basis for derivation of the simulation model and provides an approach for the FSW simulation in A12024-T3 and is potentially more useful than models derived previously.展开更多
From April to July 2018,a data sample at the peak energy of the T(4 S) resonance was collected with the Belle Ⅱ detector at the SuperKEKB electron-positron collider.This is the first data sample of the Belle Ⅱ exper...From April to July 2018,a data sample at the peak energy of the T(4 S) resonance was collected with the Belle Ⅱ detector at the SuperKEKB electron-positron collider.This is the first data sample of the Belle Ⅱ experiment.Using Bhabha and digamma events,we measure the integrated luminosity of the data sample to be(496.3±0.3±3.0) pb-1,where the first uncertainty is statistical and the second is systematic.This work provides a basis for future luminosity measurements at Belle Ⅱ.展开更多
Linear Least Square (LLS) is an approach for modeling regression analysis, applied for prediction and quantification of the strength of relationship between dependent and independent variables. There are a number of m...Linear Least Square (LLS) is an approach for modeling regression analysis, applied for prediction and quantification of the strength of relationship between dependent and independent variables. There are a number of methods for solving the LLS problem but as soon as the data size increases and system becomes ill conditioned, the classical methods become complex at time and space with decreasing level of accuracy. Proposed work is based on prediction and quantification of the strength of relationship between sugar fasting and Post-Prandial (PP) sugar with 73 factors that affect diabetes. Due to the large number of independent variables, presented problem of diabetes prediction also presented similar complexities. ABS method is an approach proven better than other classical approaches for LLS problems. ABS algorithm has been applied for solving LLS problem. Hence, separate regression equations were obtained for sugar fasting and PP severity.展开更多
基金the financial support provided by the Biotechnology Information Service–Sub-Distributed Information Centre(supported by the Department of Biotechnology,Government of India)Advanced Bioinformatics Centre(supported by the Government of Rajasthan)at Birla Institute of Scientific Research for the infrastructure and facilities for conducting statistical work
文摘Objective： To determine the clinical serum levels of carcinoembryonic antigen （CEA） and carbohydrate antigen 19-9 （CA19-9）, individually and in combination, for the diagnosis of 50 healthy subjects and 150 cases of esophageal, gastric, and colon cancers. Methods： The sensitivities of the two markers were compared individually and in combination, with specificity set at 100%. Receiver operating characteristic （ROC） curves were plotted. Results： Serum CEA levels were significantly higher in cancer patients than in the control group. The sensitivity of CEA was determined： in esophageal cancer, sensitivity=28%, negative predictive value （NPV）=61.72%, and AUC=0.742 （SE=0.05）, with a significance level of P〈0.0001; in gastric cancer, sensitivity=30%, NPV=58.82%, and AUC=0.734 （SE=0.0S）, with a significance level of P〈0.0001; in colon cancer, sensitivity=74%, NPV=79.36%, and AUC=0.856 （SE=0.04）, with a significance level of P〈0.0001. The sensitivity of CA19-9 was also evaluated： in esophageal cancer, sensitivity=18%, NPV=54.94%, and AUC=0.573 （SE=0.05）, with a significance level of P=0.2054. In gastric cancer, sensitivity=42%, NPV=63.29%, and AUC=0.679 （SE=0.05）, with a significance level of P〈0.0011. In colon cancer, sensitivity=26%, NPV=57.47%, and AUC=0.S80 （SE=0.05）, with a significance level ofP=0.1670. The following were the sensitivities of CEA/CA19-9 combined： in esophageal cancer, sensitivity=42%, NPV=63.29%, SE=0.078 （95% CI： 0.0159-0.322）; gastric cancer, sensitivity=S8%, NPV=70.42%, SE=0.072 （9$% CI： -0.0866-0.198）; and colon cancer, sensitivity=72%, NPV=78.12%, SE=0.070 （9S% CI： 0.137-0.415）. Conclusion： CEA exhibited the highest sensitivity for colon cancer, and CA19-9 exhibited the highest sensitivity for gastric cancer. Combined analysis indicated an increase in diagnostic sensitivity in esophageal and gastric cancer compared with that in colon cancer.
文摘Treatment of reverse oblique trochanteric femoral fractures poses a lot of challenges. There have been proponents of intramedullary devices as well as extramedullary devices. We present the results of proximal femoral nailing surgery performed for reverse obliquity intertrochanteric fractures using two proximal lag screws and a nail of 250 mm. There is prospective study of fifty three patients with AO/OTA 31 A-A3 fractures being treated by proximal femoral nailing in our institute after seeking approval from the Hospital ethics board. The quality of the reduction, the operative time, complications and the functional status of the patients were the parameters on which the results were evaluated. The mean Harris hip score was 76.66 (range 70 - 93) and the mean Barthel activity score was 16.21 (range 12 - 20). The average surgical time was 50 minutes and the mean consolidation time was 11.5 weeks. Intramedullary nailing with proximal femoral nails seems to be a good option in the treatment of reverse obliquity intertrochanteric fractures as against the various existing options available for the management.
文摘Getting the trajectory of the proximal femoral nail in the right direction is essential to achieve a good result in the technically demanding surgery of proximal femoral fracture. Either an inappropriate starting point or a failure to match the chosen implant’s lateral entry angle may cause coronal plane deformity after trochanteric entry nailing. The lateral view is the critical view for localization of the proper starting point. For the right execution of the surgery, getting the trajectoy right is fully under the control of the surgeon and should always be attempted.
文摘A multiple power quality(MPQ)disturbance has two or more power quality(PQ)disturbances superimposed on a voltage signal.A compact and robust technique is required to identify and classify the MPQ disturbances.This manuscript investigated a hybrid algorithm which is designed using parallel processing of voltage with multiple power quality(MPQ)disturbance using stockwell transform(ST)and hilbert transform(HT).This will reduce the computational time to identify theMPQdisturbances,whichmakes the algorithm fast.A MPQ identification index(IPI)is computed using statistical features extracted from the voltage signal using the ST and HT.IPI has different patterns for various types of MPQ disturbances which effectively identify the MPQ disturbances.A MPQ time location index(IPL)is computed using the features extracted from the voltage signal using ST and HT.IPL effectively identifies the initiation and end of PQ disturbances and thereby locates the MPQ events with respect to time.Classification of MPQ disturbances is performed using decision rules in both the noise-free and noisy environments with a 20 dB noise to signal ratio(SNR).The performance of the proposed hybrid algorithm using ST and HT with rule-based decision tree(RBDT)is better compared to the ST and RBDT techniques in terms of accuracy of classification of MPQ disturbances.MATLAB software is used to perform the study.
文摘The COVID-19 pandemic has created a major challenge for countries all over the world and has placed tremendous pressure on their public health care services.An early diagnosis of COVID-19 may reduce the impact of the coronavirus.To achieve this objective,modern computation methods,such as deep learning,may be applied.In this study,a computational model involving deep learning and biogeography-based optimization(BBO)for early detection and management of COVID-19 is introduced.Specifically,BBO is used for the layer selection process in the proposed convolutional neural network(CNN).The computational model accepts images,such as CT scans,X-rays,positron emission tomography,lung ultrasound,and magnetic resonance imaging,as inputs.In the comparative analysis,the proposed deep learning model CNNis compared with other existingmodels,namely,VGG16,InceptionV3,ResNet50,and MobileNet.In the fitness function formation,classification accuracy is considered to enhance the prediction capability of the proposed model.Experimental results demonstrate that the proposed model outperforms InceptionV3 and ResNet50.
基金This study was supported by a grant from Gujarat Council of Scientific Technology(GUJCOST),Ahmedabad.
文摘The objective of this study was to develop novel transanasl microemulsion containing carbamazepine for treatment of epilepsy.Oleic acid was selected as oil while Tween 80 and propylene glycol were selected as surfactant and cosurfactant respectively based on solubility results.Optimized ratio of Tween 80:propylene glycol was selected after developing pseudoternary phase diagrams for different ratio and microemulsions were prepared.The prepared microemulsions were evaluated for globule size,viscosity,pH,conductivity and%transmittance.Exvivo diffusion study for optimized microemulsion was performed through sheep nasal mucosa wherein diffusion flux and permeability coefficients were determined.Further pharmacodynamic performance was evaluated in rats by electrically induced seizures.It was found that optimized microemulsion was stable and transparent with average globule size of 190 nm and diffusion flux of 75.77 mg cm2 min1 and showed no toxicity during histopathological evaluation on sheep nasal mucosa.Pharmacodynamic evaluation also indicated lesser intensity of seizures in rats treated with optimized formulation in comparison to rats treated with oral carbamazepine microemulsion and nasal carbamazepine solution which suggested carbamazepine transnasal delivery system as an effective alternate therapy for treatment of epilepsy.
文摘Obstructive jaundice in the setting of a hilar mass raises strong suspicion of a cholangiocarcinoma,with diagnosis usually made on imaging.Jaundice,when present in patients with hepatocellular carcinoma,is mostly related to underlying liver disease(i.e.cirrhosis)and only rarely to diffuse tumor infiltration of liver parenchyma or hilar invasion.We report here the good outcome of a 67 year-old patient who presented with obstructive jaundice,underwent surgery and was given a diagnosis of hepatocellular carcinoma,which was made only at histopathological examination of resected specimen.
文摘A case of 16 yrs male patient with parosteal lipoma affecting the lower metaphyseal end of the left femur is presented. Clinical suspicion, plain radiographs, CT (Plain and 3 D) as well as MRI suggested a diagnosis of parosteal lipoma. Lipomas may be defined as benign lesions of mature adipose tissue without evidence of cellular atypia [1]. Lipomas are the most common soft tissue lesions and surprisingly are among the rarest bone neoplasias. The most frequent complaints are a tumoral convexity presenting as a visible or palpable mass or a mild-intensity, dull pain. The parosteal type is a rare tumor accounting for 0.3% of all lipomas [2] and is usually asymptomatic. It is seen commonly affecting adults aged over 40 [3]. The present article describes a rare case of parosteal lipoma located in the femur, with extensive hyperostosis visible on plain xray and confirmed by imaging studies (CT and MRI). Unlike the parosteal lipomas reported in adults over 40 yrs in this case it presented in a much younger age group.
文摘This study introduces a two-level strategy for efficient execution of multiple sequence alignment (MSA) of complex heterogeneous sequences. The two levels of the proposed technique are comprised of: designing the discrete firefly algorithm (DFFA) for the formation and implementation of makespan minimisation on parallel machines, followed by performing Ctrie-based caching for pairwise alignment to reduce the load on the data servers for handling multiple queries. The proposed strategy addresses a multi-client problem that aims to acquire the full advantage of the computational power of parallel connected machines. Further, it is shown that the inclusion of Ctrie as caching mechanism successively improves the performance of the system with accretion in several sequences. Performance of proposed DFFA is also compared with discrete versions of four swarm intelligence based algorithms at the criteria of makespan minimisation and the rate of convergence on two kinds of complex and diverse datasets. The work is unique in this sense: it is the first swarm-intelligence-based implementation for the addressed problem;it is so far the first approach for Ctrie based caching of the MSA on the scheduled parallel machines;hybridisation of DFFA with Ctrie for caching the MSA results is also a novel implementation.
基金the University of Malaya (MU) that awarded UMRG Grants RG042/09AETand RG088/10AET to the authors for research work to beconducted at the University of MalayaSpecial thanks are given to CREAM-CIDB for providing partial financial support to the first author via Project CREAM/R&D-08//3/2(8)
文摘Heat flux characteristics are critical to good quality welding obtained in the important engineering alloy A12024- T3 by the friction stir welding （FSW） process. In the present study, thermocouples in three different configurations were amxed on the welding samples to measure the temperatures： in the first configuration, four thermocouples were placed at equivalent positions along one side of the welding direction; the second configuration involved two equivalent thermocouple locations on either side of the welding path; while the third configuration had all the thermocouples on one side of the layout but with unequal gaps from the welding line. A three-dimensional, non-linear ANSYS computational model, based on an approach applied to A12024-T3 for the first time, was used to simulate the welding temperature profiles obtained experimentally. The experimental thermal profiles on the whole were found to be in agreement with those calculated by the ANSYS model. The broad agreement between the two kinds of profiles validates the basis for derivation of the simulation model and provides an approach for the FSW simulation in A12024-T3 and is potentially more useful than models derived previously.
基金supported by the following funding sources:Science Committee of the Republic of Armenia Grant No.18T-1C180Australian Research Council and research grant Nos.DP180102629,DP170102389,DP170102204,DP150103061,FT130100303,and FT130100018+22 种基金Austrian Federal Ministry of Education,Science and Research,and Austrian Science Fund No.P 31361-N36Natural Sciences and Engineering Research Council of Canada,Compute Canada and CANARIEChinese Academy of Sciences and research grant No.QYZDJ-SSW-SLH011National Natural Science Foundation of China and research grant Nos.11521505,11575017,11675166,11761141009,11705209,and 11975076LiaoNing Revitalization Talents Program under contract No.XLYC1807135Shanghai Municipal Science and Technology Committee under contract No.19ZR1403000Shanghai Pujiang Program under Grant No.18PJ1401000the CAS Center for Excellence in Particle Physics(CCEPP)the Ministry of Education,Youth and Sports of the Czech Republic under Contract No.LTT17020Charles University grants SVV260448 and GAUK 404316European Research Council,7th Framework PIEF-GA-2013-622527Horizon 2020 Marie Sklodowska-Curie grant agreement No.700525’NIOBE,’Horizon 2020 Marie Sklodowska-Curie RISE project JENNIFER grant agreement No.644294Horizon 2020 ERC-Advanced Grant No.267104NewAve No.638528(European grants)L’Institut National de Physique Nucléaire et de Physique des Particules(IN2P3)du CNRS(France),BMBF,DFG,HGF,MPG and AvH Foundation(Germany)Department of Atomic Energy and Department of Science and Technology(India)Israel Science Foundation grant No.2476/17United States-Israel Binational Science Foundation grant No.2016113Istituto Nazionale di Fisica Nucleare and the research grants BELLE2Japan Society for the Promotion of Science,Grant-in-Aid for Scientific Research grant Nos.16H03968,16H03993,16H06492,16K05323,17H01133,17H05405,18K03621,18H03710,18H05226,19H00682,26220706,and 26400255the National Institute of Informatics,and Science Information NETwork 5(SINET5)the Ministry of Education,Culture,Sports,Science,an
文摘From April to July 2018,a data sample at the peak energy of the T(4 S) resonance was collected with the Belle Ⅱ detector at the SuperKEKB electron-positron collider.This is the first data sample of the Belle Ⅱ experiment.Using Bhabha and digamma events,we measure the integrated luminosity of the data sample to be(496.3±0.3±3.0) pb-1,where the first uncertainty is statistical and the second is systematic.This work provides a basis for future luminosity measurements at Belle Ⅱ.
文摘Linear Least Square (LLS) is an approach for modeling regression analysis, applied for prediction and quantification of the strength of relationship between dependent and independent variables. There are a number of methods for solving the LLS problem but as soon as the data size increases and system becomes ill conditioned, the classical methods become complex at time and space with decreasing level of accuracy. Proposed work is based on prediction and quantification of the strength of relationship between sugar fasting and Post-Prandial (PP) sugar with 73 factors that affect diabetes. Due to the large number of independent variables, presented problem of diabetes prediction also presented similar complexities. ABS method is an approach proven better than other classical approaches for LLS problems. ABS algorithm has been applied for solving LLS problem. Hence, separate regression equations were obtained for sugar fasting and PP severity.
