目的评价橡皮圈组织夹内牵引辅助内镜黏膜下剥离术(rubber band and clip facilitated endoscopic submucosal dissection,RAC-ESD)治疗结直肠病变的安全性和有效性。方法采用回顾性队列研究方法,分析2018年9月—2019年8月间在北京大学...目的评价橡皮圈组织夹内牵引辅助内镜黏膜下剥离术(rubber band and clip facilitated endoscopic submucosal dissection,RAC-ESD)治疗结直肠病变的安全性和有效性。方法采用回顾性队列研究方法,分析2018年9月—2019年8月间在北京大学第一医院内镜中心接受内镜黏膜下剥离术(endoscopic submucosal dissection,ESD)治疗,符合纳入和排除标准的115例结直肠病变患者,依照ESD手术方式分为RAC-ESD组(n=34)及传统ESD组(n=81),比较两组间手术时间、单位时间切除面积、整块切除率、完全切除率、治愈性切除率、并发症发生率及肿瘤复发率等指标。结果RAC-ESD组中位标本面积6-32(7-53)cm^(2),中位手术时间40-0(55-0)min,中位单位时间切除面积0-14(0-20)cm^(2)/min。传统ESD组中位标本面积4-71(5-02)cm^(2),中位手术时间50-0(50-0)min,中位单位时间切除面积0-09(0-07)cm^(2)/min。RAC-ESD组标本面积略大于传统ESD组,手术时间略短于传统ESD组,但差异均无统计学意义(P均>0-05)。RAC-ESD组单位时间切除面积明显大于传统ESD组(P=0-008)。RAC-ESD组整块切除率、完全切除率及治愈性切除率分别为100-0%(34/34)、100-0%(34/34)及97-1%(33/34),传统ESD组分别为100-0%(81/81)、96-3%(78/81)和91-4%(74/81)。两组均无操作相关并发症发生。经过(10-0±5-5)个月随访,两组均无局部复发。结论RAC-ESD治疗结直肠病变可提高手术效率,安全有效。展开更多
Dear Editor,This letter presents a novel segmentation approach that leverages dendritic neurons to tackle the challenges of medical imaging segmentation.In this study,we enhance the segmentation accuracy based on a Se...Dear Editor,This letter presents a novel segmentation approach that leverages dendritic neurons to tackle the challenges of medical imaging segmentation.In this study,we enhance the segmentation accuracy based on a SegNet variant including an encoder-decoder structure,an upsampling index,and a deep supervision method.Furthermore,we introduce a dendritic neuron-based convolutional block to enable nonlinear feature mapping,thereby further improving the effectiveness of our approach.展开更多
Lead, zinc, and iron were recovered from jarosite residues using direct reduction followed by magnetic separation. The influence of the coal dosage, reduction temperature, and reduction time on the volatilization rate...Lead, zinc, and iron were recovered from jarosite residues using direct reduction followed by magnetic separation. The influence of the coal dosage, reduction temperature, and reduction time on the volatilization rates of lead and zinc and the metallization rate of iron were investigated. The results show that the volatilization rates of lead and zinc were 96.97% and 99.89%, respectively, and the iron metallization rate was 91.97% under the optimal reduction roasting conditions of a coal dosage of 25.0 wt% and reduction roasting at 1250°C for 60 min. The magnetic concentrate with an iron content of 90.59 wt% and an iron recovery rate of 50.87% was obtained under the optimum conditions in which 96.56% of the reduction product particles were smaller than 37 μm and the magnetic field strength was 24 k A/m. Therefore, the results of this study demonstrate that recovering valuable metals such as lead, zinc, and iron from jarosite residues is feasible using the developed approach.展开更多
Mycoplasma gallisepticum HS strain(MG-HS)is a pathogen that causes chronic respiratory disease(CRD)in chicken,which is characterized by host respiratory inflammatory damage,brings huge economic losses to the poultry i...Mycoplasma gallisepticum HS strain(MG-HS)is a pathogen that causes chronic respiratory disease(CRD)in chicken,which is characterized by host respiratory inflammatory damage,brings huge economic losses to the poultry industry.Recently,emerging Chinese herbal medicines(CHM)have been used to treat CRD.This study was aimed to investigate the preventive and therapeutic effects and their potential mechanisms of Chinese herbal medicinal formulae(CHMF),which consisted of 10 kinds of Chinese herbal medicine including Scutellaria,Houttuynia cordate and licorice,on MGinduced CRD in chickens.With respect to the preventive effect,the results showed that CHMF could effectively recover the MG-induced decrease on body weight and feed conversion ratio.Histopathological analysis showed that both prevention and treatment of CHMF could significantly alleviate the severe respiratory inflammation induced by MG infection.Moreover,compared with the MG infection group,both the prevention groups and the treatment groups of CHMF could effectively reduce the expression of MG adhesion protein(p MGA1.2)to inhibit the proliferation of MG,and thus effectively inhibit the expression of MG-induced inflammatory factors interleukin-1β(IL-1β)and tumour necrosis factor-α(TNF-α).In summary,these findings confirm that CHMF can protect chickens from various tissue damage caused by MG infection and has no adverse effects on the performance of chickens in the short term.And its efficacy against MG is equal to or better than that of tiamulin.展开更多
An Nd:YAG single pulse nanosecond laser of 532 nm wavelength with an 8 ns pulse width was projected on the soil samples collected from the campus of Bengbu College under 1 standard atmospheric pressure. Laser-induced ...An Nd:YAG single pulse nanosecond laser of 532 nm wavelength with an 8 ns pulse width was projected on the soil samples collected from the campus of Bengbu College under 1 standard atmospheric pressure. Laser-induced breakdown spectroscopy at different sample temperatures was achieved. The intensity and signal-to-noise ratio (SNR) changes of different characteristic spectral lines could be analyzed when the sample temperature changes.The evolution of plasma electron temperature and electron density with the sample temperature was analyzed through Boltzmann oblique line method and Stark broadening method.The cause of the radiation enhancement of laser-induced metal plasma was discussed. Experimental results demonstrated that the spectral intensity, SNR, the electron temperature and electron density of plasma are positively related to the sample temperature, and reach saturation at 100℃.展开更多
文摘目的评价橡皮圈组织夹内牵引辅助内镜黏膜下剥离术(rubber band and clip facilitated endoscopic submucosal dissection,RAC-ESD)治疗结直肠病变的安全性和有效性。方法采用回顾性队列研究方法,分析2018年9月—2019年8月间在北京大学第一医院内镜中心接受内镜黏膜下剥离术(endoscopic submucosal dissection,ESD)治疗,符合纳入和排除标准的115例结直肠病变患者,依照ESD手术方式分为RAC-ESD组(n=34)及传统ESD组(n=81),比较两组间手术时间、单位时间切除面积、整块切除率、完全切除率、治愈性切除率、并发症发生率及肿瘤复发率等指标。结果RAC-ESD组中位标本面积6-32(7-53)cm^(2),中位手术时间40-0(55-0)min,中位单位时间切除面积0-14(0-20)cm^(2)/min。传统ESD组中位标本面积4-71(5-02)cm^(2),中位手术时间50-0(50-0)min,中位单位时间切除面积0-09(0-07)cm^(2)/min。RAC-ESD组标本面积略大于传统ESD组,手术时间略短于传统ESD组,但差异均无统计学意义(P均>0-05)。RAC-ESD组单位时间切除面积明显大于传统ESD组(P=0-008)。RAC-ESD组整块切除率、完全切除率及治愈性切除率分别为100-0%(34/34)、100-0%(34/34)及97-1%(33/34),传统ESD组分别为100-0%(81/81)、96-3%(78/81)和91-4%(74/81)。两组均无操作相关并发症发生。经过(10-0±5-5)个月随访,两组均无局部复发。结论RAC-ESD治疗结直肠病变可提高手术效率,安全有效。
基金partially supported by the Japan Society for the Promotion of Science(JSPS)KAKENHI(JP22H03643)Japan Science and Technology Agency(JST)Support for Pioneering Research Initiated by the Next Generation(SPRING)(JPMJSP2145)JST through the Establishment of University Fellowships Towards the Creation of Science Technology Innovation(JPMJFS2115)。
文摘Dear Editor,This letter presents a novel segmentation approach that leverages dendritic neurons to tackle the challenges of medical imaging segmentation.In this study,we enhance the segmentation accuracy based on a SegNet variant including an encoder-decoder structure,an upsampling index,and a deep supervision method.Furthermore,we introduce a dendritic neuron-based convolutional block to enable nonlinear feature mapping,thereby further improving the effectiveness of our approach.
文摘Lead, zinc, and iron were recovered from jarosite residues using direct reduction followed by magnetic separation. The influence of the coal dosage, reduction temperature, and reduction time on the volatilization rates of lead and zinc and the metallization rate of iron were investigated. The results show that the volatilization rates of lead and zinc were 96.97% and 99.89%, respectively, and the iron metallization rate was 91.97% under the optimal reduction roasting conditions of a coal dosage of 25.0 wt% and reduction roasting at 1250°C for 60 min. The magnetic concentrate with an iron content of 90.59 wt% and an iron recovery rate of 50.87% was obtained under the optimum conditions in which 96.56% of the reduction product particles were smaller than 37 μm and the magnetic field strength was 24 k A/m. Therefore, the results of this study demonstrate that recovering valuable metals such as lead, zinc, and iron from jarosite residues is feasible using the developed approach.
基金supported by the National Natural Science Foundation of China(31972681)the National Key Research and Development Program of China(2017YFD0501500)。
文摘Mycoplasma gallisepticum HS strain(MG-HS)is a pathogen that causes chronic respiratory disease(CRD)in chicken,which is characterized by host respiratory inflammatory damage,brings huge economic losses to the poultry industry.Recently,emerging Chinese herbal medicines(CHM)have been used to treat CRD.This study was aimed to investigate the preventive and therapeutic effects and their potential mechanisms of Chinese herbal medicinal formulae(CHMF),which consisted of 10 kinds of Chinese herbal medicine including Scutellaria,Houttuynia cordate and licorice,on MGinduced CRD in chickens.With respect to the preventive effect,the results showed that CHMF could effectively recover the MG-induced decrease on body weight and feed conversion ratio.Histopathological analysis showed that both prevention and treatment of CHMF could significantly alleviate the severe respiratory inflammation induced by MG infection.Moreover,compared with the MG infection group,both the prevention groups and the treatment groups of CHMF could effectively reduce the expression of MG adhesion protein(p MGA1.2)to inhibit the proliferation of MG,and thus effectively inhibit the expression of MG-induced inflammatory factors interleukin-1β(IL-1β)and tumour necrosis factor-α(TNF-α).In summary,these findings confirm that CHMF can protect chickens from various tissue damage caused by MG infection and has no adverse effects on the performance of chickens in the short term.And its efficacy against MG is equal to or better than that of tiamulin.
基金supported by the National Natural Science Foundation of China(No.11604003)Anhui Province Key Laboratory of Optoelectronic Materials Science and Technology(OMST201703)the Natural Science Foundations of Bengbu College(No.2017ZR11zd)
文摘An Nd:YAG single pulse nanosecond laser of 532 nm wavelength with an 8 ns pulse width was projected on the soil samples collected from the campus of Bengbu College under 1 standard atmospheric pressure. Laser-induced breakdown spectroscopy at different sample temperatures was achieved. The intensity and signal-to-noise ratio (SNR) changes of different characteristic spectral lines could be analyzed when the sample temperature changes.The evolution of plasma electron temperature and electron density with the sample temperature was analyzed through Boltzmann oblique line method and Stark broadening method.The cause of the radiation enhancement of laser-induced metal plasma was discussed. Experimental results demonstrated that the spectral intensity, SNR, the electron temperature and electron density of plasma are positively related to the sample temperature, and reach saturation at 100℃.
