Peripheral primitive neuroectodermal tumor(PNET) of the kidney is a rare, aggressive tumor known for its recurrence and metastatic potential. Despite the frequency of venous extension to the renal veins and inferior v...Peripheral primitive neuroectodermal tumor(PNET) of the kidney is a rare, aggressive tumor known for its recurrence and metastatic potential. Despite the frequency of venous extension to the renal veins and inferior vena cava, pulmonary tumor embolism at the initial presentation is not common. We report a case of 22-year-old female with PNET of the kidney who presented with tumor embolism in the inferior vena cava(IVC) and bilateral pulmonary artery. The patient underwent surgical resection and histopathological analysis confirmed the presence of tumor within the IVC and pulmonary arteries. The patient received adjuvant chemotherapy and is currently doing well on follow-up.展开更多
Within the framework of independent electron approach,the prior form of boundary corrected continuum intermediate state(BCCIS)approximation is employed to calculate the cross sections for total single electron capture...Within the framework of independent electron approach,the prior form of boundary corrected continuum intermediate state(BCCIS)approximation is employed to calculate the cross sections for total single electron capture in collision of bare ions(H^+,He^2+ and Li^3+)with biological molecules in the intermediate to high energy regimes.With a suitable choice of the distorting potential,the boundary condition is satisfied with a proper account of the intermediate continuum states.The cross sections have been calculated from 25 keV/amu to 10 MeV/amu.We have approximated the cross sections for molecular targets by the linear combination of atomic cross sections weighted by the effective occupation electron number.Furthermore,the multi-electronic problem is reduced to a mono-electronic one using a version of the independent electron approximation.A detailed analysis on the contributions from different molecular orbitals to total cross sections is reported.In the present investigation,we observe clearly the importance of the core contribution in the change of slope of the TCS curves.Moreover,analysis has been made on the cross section per target electron resulting in achievement of a‘universal'cross section.However,some negligible discrepancies are observed for the case of the CH4 molecule.The present computed results in prior from of BCCIS method have been compared with the available theoretical and experimental results.We found that our computed results are in good agreement with the experimental findings.展开更多
Primary central nervous system lymphoma(PCNSL) is a rare disease in pediatric age group. A thirteen-yearold male child presented with complaints of headache for six months, vomiting and diplopia for three days. Magnet...Primary central nervous system lymphoma(PCNSL) is a rare disease in pediatric age group. A thirteen-yearold male child presented with complaints of headache for six months, vomiting and diplopia for three days. Magnetic resonance imaging of the brain showed a single lesion of 1.7 cm × 1.6 cm × 1.6 cm in the mid brain and tectum. He underwent a gross total resection of the tumor. The histopathological evaluation revealed B cell high grade non Hodgkin lymphoma. The patient was treated with High dose methotrexate and cranio spinal radiation. The patient was alive without disease 12 mo after completion of treatment. This case highlights importance of keeping PCNSL as differential in brain stem lesions of pediatric patients also. Radiation and chemotherapy remains the most important treatment for such patients.展开更多
Identification of unknown remains recovered from marine and terrestrial locations is a significant humanitarian problem.This investigation proposes a simple method applicable to fragmentary femora for a more refined l...Identification of unknown remains recovered from marine and terrestrial locations is a significant humanitarian problem.This investigation proposes a simple method applicable to fragmentary femora for a more refined level of ancestry and/or sex estimation.To that end,we re-examined Purkait’s triangle which involves three inter-landmark distances between the traction epiphyses and the articular rim of femoral head.A large sample(n=584)from geographically diverse(Egyptian,Indian and Greek)populations was compiled.Additionally,shape(n=3)and trigonometrically derived variables and ratios(n=9 variables)were employed to detect any geographically-clustered morphological differences between these populations.Random forest modelling(RFM)and linear discriminant function analysis(LDA)were employed to create classification models in instances where sex was known or unknown.The sample was apportioned into training and test sets with a ratio 70/30.The classification accuracies were evaluated by means of k fold cross-validation procedure.In sex estimation,RFM showed similar performance to LDA.However,RFM outperformed LDA in ancestry estimation.Ancestry estimation was satisfactory in the Indian and Egyptian samples albeit the Greek sample was problematic.The Greek samples presented greater morphological overlap with the Indian sample due to high within-group variation.Test samples were accurately assigned to their ancestral category when sex was known.Generally,higher classification accuracies in the validation sample were obtained in the sex-specific model of females than in males.Using RFM and the linear variables,the overall accuracy reached 83%which is distributed as 95%,71%and 86%for the Egyptian,Indian and Greek females,respectively;whereas in males,the overall accuracy is 72%and is distributed as 58%,87%and 50%for the Egyptian,Indian and Greek males,respectively.Classification accuracies were also calculated per group in the test data using the 12 derived variables.For the females,the accuracies using the medians model 展开更多
Improper prescribing habits and inappropriate drug use lead to serious health and economic consequences. This study was undertaken to evaluate drug utilization services and prescription patterns of homeopathic doctors...Improper prescribing habits and inappropriate drug use lead to serious health and economic consequences. This study was undertaken to evaluate drug utilization services and prescription patterns of homeopathic doctors in a government homeopathic teaching hospital in India. METHODS： No standardized homeopathic drug use indicators are available. The researchers used indicators for health care setting （drug availability）-modified prescribing indicators and patient care indicators, based on World Health Organization＇s core drug use indicators. A cross- sectional, prospective, institutional, observational study of 2-month duration with record analysis was conducted on 600 patients visiting seven different outpatient departments （OPDs） for the first time at Mahesh Bhattacharyya Homeopathic Medical College ＆ Hospital, Howrah, West Bengal, India, using the developed indicators. RESULTS： Overall availability of prescribed drugs was quite satisfactory （92.28%）. Centesimal potencies accounted for the majority of prescriptions （74.76%）. There was a poor record of diagnosis （39.17%） except in the OPDs of Gynecology and Obstetrics （68.48%, P 〈 0.01） and Dermatology （64.58%, P 〈 0.01）. Records of investigational findings and ongoing therapies, if any, were also poor except OPDs of Gynecology and Obstetrics, and Pediatrics. Structure of prescriptions was maintained satisfactorily in all the OPDs. Though tendency of using ＇individualized homeopathy＇ predominated, there also existed the use of ＇polypharmacy＇. Mean consultation time was 5.9 min. Labeling was extremely poor and is an area needing improvement. The prescriptions were highly legible. CONCLUSION： This was a preliminary study, conducted for the first time in homeopathy using newly developed indicators that yield meaningful results. Further studies are necessary in order to evaluate the different factors involved and to plan future interventions to improve the quality of care in healthcare settings.展开更多
Objective:To look for change in relative renal function and document renal scarring following endoscopic renal pelvic instillation sclerotherapy(RPIS)in patients with chyluria by dimercaptosuccinic acid(DMSA)renal sca...Objective:To look for change in relative renal function and document renal scarring following endoscopic renal pelvic instillation sclerotherapy(RPIS)in patients with chyluria by dimercaptosuccinic acid(DMSA)renal scan.Methods:A prospective study was performed between November 2015 and September 2016.All patients with biochemically documented chyluria who underwent RPIS using either 1%-silver nitrate or 0.1%-povidine iodine were included.Patients received either 3-,6-or 9-doses.DMSA renal scan was performed before and 2e3 months after sclerotherapy.Results:Of the 34 patients,22 were males.Mean age was 41.08±16.64 years(range,15-70 years).Thirty-two patients(94.1%)responded to therapy while two did not respond even after 9-doses.Average follow-up was 8.94±3.70 months.The mean relative renal function(preinstillation)of normal kidney was 50.76%±3.55%while that of affected renal unit(side of instillation)was 49.20%±3.44%(range,43.0%-61.0%).After instillation therapy,the mean relative renal function of normal side was 52.26%±3.57%while that of affected renal unit was 47.50%±3.56%(range,41.0%-54.0%).The relative renal function did not change>5%from the baseline value in any patient except one(in which the differential function increased paradoxically by 12%).Two patients developed renal scar in post-instillation renal scan.Conclusion:Endoscopic sclerotherapy in chyluria is safe and effective.The relative renal function does not deteriorate by more than 5%.There is a small risk of development of renal scar.More studies involving larger number of patients are needed to answer this dilemma.展开更多
Researchers have been exploring dielectric testing techniques both in time and frequency domain for insulation condition assessment of oil-paper insulated transformers.In a practical dielectric system,dipoles are foun...Researchers have been exploring dielectric testing techniques both in time and frequency domain for insulation condition assessment of oil-paper insulated transformers.In a practical dielectric system,dipoles are found to behave according to a distribution of elementary Debye relaxation properties.Suitable distribution density functions have been proposed to characterise such many-body interaction processes.Cole-Cole diagrams can be one of the methods for studying the nature of frequency dependency of dielectric materials of complex structure.Cole-Cole plots are commonly used for characterising different materials such as dielectric mixtures,ionic liquids,cable insulating oil,polar liquids etc.The scope of its application for assessing transformer oil-paper insulation considering distributed relaxation process has not been explored yet.The present contribution discusses mathematical formulations used for transforming the experimentally obtained time domain dielectric response test data to distribution domain and further to frequency domain for obtaining the Cole-Cole plots.Findings about the influence of various operating conditions and insulation status on the Cole-Cole diagram have been reported in this contribution.Results of tests on field transformers are also presented.This paper attempts to employ the features of Cole-Cole diagrams as potential indicators for analysing condition of the oil-paper insulation considering distributed relaxation process.展开更多
Natural kaolin (NK) and magnetite-modified kaolin (MK) prepared by co-precipitation were used as adsorbents to remove phosphate from aqueous solution. The materials were characterized using X-ray diffractometer (XRD),...Natural kaolin (NK) and magnetite-modified kaolin (MK) prepared by co-precipitation were used as adsorbents to remove phosphate from aqueous solution. The materials were characterized using X-ray diffractometer (XRD), Fourier transform infrared spectroscopy (FTIR), field-emission scanning electron microscope (FESEM), and vibrating sample magnetometer (VSM). Batch adsorption experiment was carried out to determine the phosphate removal efficiencies of these materials. The magnetic-supported kaolin showed better dispersion and less co-aggregation which ensured better fusion of the kaolin with magnetite (Fe3O4). The removal process of phosphate was governed by physico-chemical process. The results demonstrated that the adsorption of phosphate onto NK and MK was highly pH-dependent and the kinetics of the adsorption followed pseudo-second order equation. The adsorption data of Mk adsorbent fitted better with the Freundlich isotherm equation. The MK showed much better adsorption capacity per mass of MK (52.91 mg/g) than untreated NK (17.61 mg/g). Since the magnetic kaolin can be easily prepared, it enables promising application for the removal of phosphate from aqueous solution. Hence, this new class of efficient adsorbent (MK), can have a variety of application in industrial processes.展开更多
The problem of arsenic(As)poisoning in the upper deltaic plains of the Ganges-Bhagirathi river system of West Bengal(WB),India,is terrifying. Elevated As(】50 ppb)in well water was observed within a depth range of 10-...The problem of arsenic(As)poisoning in the upper deltaic plains of the Ganges-Bhagirathi river system of West Bengal(WB),India,is terrifying. Elevated As(】50 ppb)in well water was observed within a depth range of 10-30 m in older grey terraces of abandoned fluvial channel deposits in the Murshidabad and Malda districts in WB.Both surface and cored(2-20 m)sediment samples from banks of the river Ganges and along a north-south transect of the main tributary Bhagirathi-Hooghly river展开更多
文摘Peripheral primitive neuroectodermal tumor(PNET) of the kidney is a rare, aggressive tumor known for its recurrence and metastatic potential. Despite the frequency of venous extension to the renal veins and inferior vena cava, pulmonary tumor embolism at the initial presentation is not common. We report a case of 22-year-old female with PNET of the kidney who presented with tumor embolism in the inferior vena cava(IVC) and bilateral pulmonary artery. The patient underwent surgical resection and histopathological analysis confirmed the presence of tumor within the IVC and pulmonary arteries. The patient received adjuvant chemotherapy and is currently doing well on follow-up.
基金The authors gratefully acknowledge the financial support from the Higher Education,Science&Technology and Biotechnology,Govt.of West Bengal,India under Grant No.239(sanc.)/ST/P/S&T/16G-48/2017.
文摘Within the framework of independent electron approach,the prior form of boundary corrected continuum intermediate state(BCCIS)approximation is employed to calculate the cross sections for total single electron capture in collision of bare ions(H^+,He^2+ and Li^3+)with biological molecules in the intermediate to high energy regimes.With a suitable choice of the distorting potential,the boundary condition is satisfied with a proper account of the intermediate continuum states.The cross sections have been calculated from 25 keV/amu to 10 MeV/amu.We have approximated the cross sections for molecular targets by the linear combination of atomic cross sections weighted by the effective occupation electron number.Furthermore,the multi-electronic problem is reduced to a mono-electronic one using a version of the independent electron approximation.A detailed analysis on the contributions from different molecular orbitals to total cross sections is reported.In the present investigation,we observe clearly the importance of the core contribution in the change of slope of the TCS curves.Moreover,analysis has been made on the cross section per target electron resulting in achievement of a‘universal'cross section.However,some negligible discrepancies are observed for the case of the CH4 molecule.The present computed results in prior from of BCCIS method have been compared with the available theoretical and experimental results.We found that our computed results are in good agreement with the experimental findings.
文摘Primary central nervous system lymphoma(PCNSL) is a rare disease in pediatric age group. A thirteen-yearold male child presented with complaints of headache for six months, vomiting and diplopia for three days. Magnetic resonance imaging of the brain showed a single lesion of 1.7 cm × 1.6 cm × 1.6 cm in the mid brain and tectum. He underwent a gross total resection of the tumor. The histopathological evaluation revealed B cell high grade non Hodgkin lymphoma. The patient was treated with High dose methotrexate and cranio spinal radiation. The patient was alive without disease 12 mo after completion of treatment. This case highlights importance of keeping PCNSL as differential in brain stem lesions of pediatric patients also. Radiation and chemotherapy remains the most important treatment for such patients.
基金study was conducted retrospectively from radiological database obtained for clinical purposes with institutional approvals.The study protocol has been approved by the Research Ethics Committee of faculty of medicine,Alexandria University,Egypt.(IRB NO.:00012098-FWA NO.:00018699,Serial NO.0304532).
文摘Identification of unknown remains recovered from marine and terrestrial locations is a significant humanitarian problem.This investigation proposes a simple method applicable to fragmentary femora for a more refined level of ancestry and/or sex estimation.To that end,we re-examined Purkait’s triangle which involves three inter-landmark distances between the traction epiphyses and the articular rim of femoral head.A large sample(n=584)from geographically diverse(Egyptian,Indian and Greek)populations was compiled.Additionally,shape(n=3)and trigonometrically derived variables and ratios(n=9 variables)were employed to detect any geographically-clustered morphological differences between these populations.Random forest modelling(RFM)and linear discriminant function analysis(LDA)were employed to create classification models in instances where sex was known or unknown.The sample was apportioned into training and test sets with a ratio 70/30.The classification accuracies were evaluated by means of k fold cross-validation procedure.In sex estimation,RFM showed similar performance to LDA.However,RFM outperformed LDA in ancestry estimation.Ancestry estimation was satisfactory in the Indian and Egyptian samples albeit the Greek sample was problematic.The Greek samples presented greater morphological overlap with the Indian sample due to high within-group variation.Test samples were accurately assigned to their ancestral category when sex was known.Generally,higher classification accuracies in the validation sample were obtained in the sex-specific model of females than in males.Using RFM and the linear variables,the overall accuracy reached 83%which is distributed as 95%,71%and 86%for the Egyptian,Indian and Greek females,respectively;whereas in males,the overall accuracy is 72%and is distributed as 58%,87%and 50%for the Egyptian,Indian and Greek males,respectively.Classification accuracies were also calculated per group in the test data using the 12 derived variables.For the females,the accuracies using the medians model
文摘Improper prescribing habits and inappropriate drug use lead to serious health and economic consequences. This study was undertaken to evaluate drug utilization services and prescription patterns of homeopathic doctors in a government homeopathic teaching hospital in India. METHODS： No standardized homeopathic drug use indicators are available. The researchers used indicators for health care setting （drug availability）-modified prescribing indicators and patient care indicators, based on World Health Organization＇s core drug use indicators. A cross- sectional, prospective, institutional, observational study of 2-month duration with record analysis was conducted on 600 patients visiting seven different outpatient departments （OPDs） for the first time at Mahesh Bhattacharyya Homeopathic Medical College ＆ Hospital, Howrah, West Bengal, India, using the developed indicators. RESULTS： Overall availability of prescribed drugs was quite satisfactory （92.28%）. Centesimal potencies accounted for the majority of prescriptions （74.76%）. There was a poor record of diagnosis （39.17%） except in the OPDs of Gynecology and Obstetrics （68.48%, P 〈 0.01） and Dermatology （64.58%, P 〈 0.01）. Records of investigational findings and ongoing therapies, if any, were also poor except OPDs of Gynecology and Obstetrics, and Pediatrics. Structure of prescriptions was maintained satisfactorily in all the OPDs. Though tendency of using ＇individualized homeopathy＇ predominated, there also existed the use of ＇polypharmacy＇. Mean consultation time was 5.9 min. Labeling was extremely poor and is an area needing improvement. The prescriptions were highly legible. CONCLUSION： This was a preliminary study, conducted for the first time in homeopathy using newly developed indicators that yield meaningful results. Further studies are necessary in order to evaluate the different factors involved and to plan future interventions to improve the quality of care in healthcare settings.
文摘Objective:To look for change in relative renal function and document renal scarring following endoscopic renal pelvic instillation sclerotherapy(RPIS)in patients with chyluria by dimercaptosuccinic acid(DMSA)renal scan.Methods:A prospective study was performed between November 2015 and September 2016.All patients with biochemically documented chyluria who underwent RPIS using either 1%-silver nitrate or 0.1%-povidine iodine were included.Patients received either 3-,6-or 9-doses.DMSA renal scan was performed before and 2e3 months after sclerotherapy.Results:Of the 34 patients,22 were males.Mean age was 41.08±16.64 years(range,15-70 years).Thirty-two patients(94.1%)responded to therapy while two did not respond even after 9-doses.Average follow-up was 8.94±3.70 months.The mean relative renal function(preinstillation)of normal kidney was 50.76%±3.55%while that of affected renal unit(side of instillation)was 49.20%±3.44%(range,43.0%-61.0%).After instillation therapy,the mean relative renal function of normal side was 52.26%±3.57%while that of affected renal unit was 47.50%±3.56%(range,41.0%-54.0%).The relative renal function did not change>5%from the baseline value in any patient except one(in which the differential function increased paradoxically by 12%).Two patients developed renal scar in post-instillation renal scan.Conclusion:Endoscopic sclerotherapy in chyluria is safe and effective.The relative renal function does not deteriorate by more than 5%.There is a small risk of development of renal scar.More studies involving larger number of patients are needed to answer this dilemma.
基金CSIR,Government of India,project grant no.22(0605)/12/EMR-II(2013-2016).
文摘Researchers have been exploring dielectric testing techniques both in time and frequency domain for insulation condition assessment of oil-paper insulated transformers.In a practical dielectric system,dipoles are found to behave according to a distribution of elementary Debye relaxation properties.Suitable distribution density functions have been proposed to characterise such many-body interaction processes.Cole-Cole diagrams can be one of the methods for studying the nature of frequency dependency of dielectric materials of complex structure.Cole-Cole plots are commonly used for characterising different materials such as dielectric mixtures,ionic liquids,cable insulating oil,polar liquids etc.The scope of its application for assessing transformer oil-paper insulation considering distributed relaxation process has not been explored yet.The present contribution discusses mathematical formulations used for transforming the experimentally obtained time domain dielectric response test data to distribution domain and further to frequency domain for obtaining the Cole-Cole plots.Findings about the influence of various operating conditions and insulation status on the Cole-Cole diagram have been reported in this contribution.Results of tests on field transformers are also presented.This paper attempts to employ the features of Cole-Cole diagrams as potential indicators for analysing condition of the oil-paper insulation considering distributed relaxation process.
文摘Natural kaolin (NK) and magnetite-modified kaolin (MK) prepared by co-precipitation were used as adsorbents to remove phosphate from aqueous solution. The materials were characterized using X-ray diffractometer (XRD), Fourier transform infrared spectroscopy (FTIR), field-emission scanning electron microscope (FESEM), and vibrating sample magnetometer (VSM). Batch adsorption experiment was carried out to determine the phosphate removal efficiencies of these materials. The magnetic-supported kaolin showed better dispersion and less co-aggregation which ensured better fusion of the kaolin with magnetite (Fe3O4). The removal process of phosphate was governed by physico-chemical process. The results demonstrated that the adsorption of phosphate onto NK and MK was highly pH-dependent and the kinetics of the adsorption followed pseudo-second order equation. The adsorption data of Mk adsorbent fitted better with the Freundlich isotherm equation. The MK showed much better adsorption capacity per mass of MK (52.91 mg/g) than untreated NK (17.61 mg/g). Since the magnetic kaolin can be easily prepared, it enables promising application for the removal of phosphate from aqueous solution. Hence, this new class of efficient adsorbent (MK), can have a variety of application in industrial processes.
文摘The problem of arsenic(As)poisoning in the upper deltaic plains of the Ganges-Bhagirathi river system of West Bengal(WB),India,is terrifying. Elevated As(】50 ppb)in well water was observed within a depth range of 10-30 m in older grey terraces of abandoned fluvial channel deposits in the Murshidabad and Malda districts in WB.Both surface and cored(2-20 m)sediment samples from banks of the river Ganges and along a north-south transect of the main tributary Bhagirathi-Hooghly river
