Vagus nerve stimulation(VNS)has been recognized by the U.S.Food and Drug Administration(FDA)as an effective alternative therapy for a wide range of diseases.However,its application is hampered by a variety of issues,i...Vagus nerve stimulation(VNS)has been recognized by the U.S.Food and Drug Administration(FDA)as an effective alternative therapy for a wide range of diseases.However,its application is hampered by a variety of issues,including high surgical risks and the long-term presence of a foreign body within the patient.Transcutaneous auricular vagus nerve stimulation(tavNs)has emerged as a non-invasive,low-cost method developed from VNS,aiming to replace surgically implanted VNS for the treatment of disease.Unlike traditional acupuncture,tavNS can be selfadministered by patients wherever possible,with a non-invasive nature and easy acceptability for patients.Compared with other auricular points,tavNS can regulate the function of internal organs by stimulating the auricular points that represent different organs.Initially,tavNS was only considered an alternative therapy to VNS for the treatment of epilepsy.However,its application has now been extended to several other diseases,including central nervous system disorders,peripheral cardiovascular diseases。展开更多
基金Supported by Young Elite Scientists Sponsorship Program by CAST:2021-2023ZGZJXH-QNRC003Beijing TCM Science and Technology Development Fund Project:BJZYON-2023-05Fundamental Research Funds for the Central Public Welfare Research Institutes:ZZ202219002,ZZ-YQ2023006。
文摘Vagus nerve stimulation(VNS)has been recognized by the U.S.Food and Drug Administration(FDA)as an effective alternative therapy for a wide range of diseases.However,its application is hampered by a variety of issues,including high surgical risks and the long-term presence of a foreign body within the patient.Transcutaneous auricular vagus nerve stimulation(tavNs)has emerged as a non-invasive,low-cost method developed from VNS,aiming to replace surgically implanted VNS for the treatment of disease.Unlike traditional acupuncture,tavNS can be selfadministered by patients wherever possible,with a non-invasive nature and easy acceptability for patients.Compared with other auricular points,tavNS can regulate the function of internal organs by stimulating the auricular points that represent different organs.Initially,tavNS was only considered an alternative therapy to VNS for the treatment of epilepsy.However,its application has now been extended to several other diseases,including central nervous system disorders,peripheral cardiovascular diseases。
