1) Background: Osteoarthritis (OA) is defined as a degenerative joint disease that mainly affects the bone. This study aims to evaluate the effect of low-intensity continuous ultrasound (LICUS) treatment on the knee o...1) Background: Osteoarthritis (OA) is defined as a degenerative joint disease that mainly affects the bone. This study aims to evaluate the effect of low-intensity continuous ultrasound (LICUS) treatment on the knee of osteoarthritis patients through home-based intervention using the LICUS medical device. 2) Methods: The clinical trials were designed in a single-arm, open-label, and intervention study. Thirty-five participants, including those who dropped out (12%), were screened and enrolled. The patients received LICUS (1.1 MHz, 1.5 W/cm2, collimated beams) on the knee by the instructions of the investigator at home (5 min/session, 3 times/day, for four-weeks). Outcome measures were assessed using the Visual Analog Scale (VAS) as a primary endpoint and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) as a secondary endpoint to evaluate pain relief and functional recovery of the knee between pre-treatment (baseline) and post-treatment (four-weeks). 3) Results: Knee pain scores measured using the VAS and WOMAC indices were significantly reduced after a four-week treatment with LICUS compared to baseline. Knee stiffness and functional capacity were significantly reduced after the LICUS application. In addition, there were no reports of adverse effects during the study period. 4) Conclusion: Long-term and home-based application of LICUS can be recommended as an alternative option for the treatment of OA patients, as evidenced by the effect of pain relief and knee function recovery.展开更多
Data clustering plays a vital role in object identification. In real life we mainly use the concept in biometric identification and object detection. In this paper we use Fuzzy Weighted Rules, Fuzzy Inference System (...Data clustering plays a vital role in object identification. In real life we mainly use the concept in biometric identification and object detection. In this paper we use Fuzzy Weighted Rules, Fuzzy Inference System (FIS), Fuzzy C-Mean clustering (FCM), Support Vector Machine (SVM) and Artificial Neural Network (ANN) to distinguish three types of Iris data called Iris-Setosa, Iris-Versicolor and Iris-Virginica. Each class in the data table is identified by four-dimensional vector, where vectors are used as the input variable called: Sepal Length (SL), Sepal Width (SW), Petal Length (PL) and Petal Width (PW). The combination of five machine learning methods provides above 98% accuracy of class identification.展开更多
In reversible data hiding, pixel value ordering is an up-to-the-minute research idea in the field of data hiding. Secret messages are embedded in the maximum or the minimum value among the pixels in a block. Pixel val...In reversible data hiding, pixel value ordering is an up-to-the-minute research idea in the field of data hiding. Secret messages are embedded in the maximum or the minimum value among the pixels in a block. Pixel value ordering helps identify the embeddable pixels in a block but suffers from fewer embedding payloads. It leaves many pixels in a block without implanting any bits there. The proposed scheme in this paper resolved that problem by allowing every pixel to conceive data bits. The method partitioned the image pixels in blocks of size two. In each block, it first orders these two pixels and then measures the average value. The average value is placed in the middle of these two pixels. Thus, the scheme extends the block size from two to three. After applying the embedding method of Weng <i><span>et al</span></i><span>., the implantation task removed the average value from the block to reduce its size again to two. These two alive pixels are called stego pixels, which produced a stego image. A piece of state information is produced during implanting to track whether a change is happening to the block’s cover pixels. This way, after embedding in all blocks, a binary stream of state information is produced, which has later been converted to decimal values. Thus, image data were assembled in a two-dimensional array. Considering the array as another image plane, Weng </span><i><span>et al</span></i><span>.’s method is again applied to embed further to produce another stego image. Model validation ensured that the proposed method performed better than previous work </span><span>i</span><span>n this field.</span>展开更多
Objective: This study aimed to evaluate the efficacy of trimetazidine on exercise capacity via a six-minute walk test in patients with ischaemic cardiomyopathy and also evaluate the effect of trimetazidine on left ven...Objective: This study aimed to evaluate the efficacy of trimetazidine on exercise capacity via a six-minute walk test in patients with ischaemic cardiomyopathy and also evaluate the effect of trimetazidine on left ventricular function via echocardiography in the same population. Methods: This prospective observational study, conducted at the National Institute of Cardiovascular Diseases in Dhaka, Bangladesh, enrolled 200 patients with ischaemic cardiomyopathy and a depressed left ventricular ejection fraction (LVEF Results: In this study (n = 200) of ischaemic cardiomyopathy patients, the mean age was 58 years, with 76% of the patients being male. All study subjects received GDMT (Guideline-Directed Medical Therapy) for angina and heart failure. Those who received the modified released form of trimetazidine developed lesions during the 1st and 2nd follow-ups, during which the LVEF, LVIDd, and six-minute walk distance significantly improved (p Conclusion: The findings of the present study demonstrated that the addition of modified-release trimetazidine to GDMT can improve exercise capacity and left ventricular function in patients with ischaemic cardiomyopathy.展开更多
文摘1) Background: Osteoarthritis (OA) is defined as a degenerative joint disease that mainly affects the bone. This study aims to evaluate the effect of low-intensity continuous ultrasound (LICUS) treatment on the knee of osteoarthritis patients through home-based intervention using the LICUS medical device. 2) Methods: The clinical trials were designed in a single-arm, open-label, and intervention study. Thirty-five participants, including those who dropped out (12%), were screened and enrolled. The patients received LICUS (1.1 MHz, 1.5 W/cm2, collimated beams) on the knee by the instructions of the investigator at home (5 min/session, 3 times/day, for four-weeks). Outcome measures were assessed using the Visual Analog Scale (VAS) as a primary endpoint and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) as a secondary endpoint to evaluate pain relief and functional recovery of the knee between pre-treatment (baseline) and post-treatment (four-weeks). 3) Results: Knee pain scores measured using the VAS and WOMAC indices were significantly reduced after a four-week treatment with LICUS compared to baseline. Knee stiffness and functional capacity were significantly reduced after the LICUS application. In addition, there were no reports of adverse effects during the study period. 4) Conclusion: Long-term and home-based application of LICUS can be recommended as an alternative option for the treatment of OA patients, as evidenced by the effect of pain relief and knee function recovery.
文摘Data clustering plays a vital role in object identification. In real life we mainly use the concept in biometric identification and object detection. In this paper we use Fuzzy Weighted Rules, Fuzzy Inference System (FIS), Fuzzy C-Mean clustering (FCM), Support Vector Machine (SVM) and Artificial Neural Network (ANN) to distinguish three types of Iris data called Iris-Setosa, Iris-Versicolor and Iris-Virginica. Each class in the data table is identified by four-dimensional vector, where vectors are used as the input variable called: Sepal Length (SL), Sepal Width (SW), Petal Length (PL) and Petal Width (PW). The combination of five machine learning methods provides above 98% accuracy of class identification.
文摘In reversible data hiding, pixel value ordering is an up-to-the-minute research idea in the field of data hiding. Secret messages are embedded in the maximum or the minimum value among the pixels in a block. Pixel value ordering helps identify the embeddable pixels in a block but suffers from fewer embedding payloads. It leaves many pixels in a block without implanting any bits there. The proposed scheme in this paper resolved that problem by allowing every pixel to conceive data bits. The method partitioned the image pixels in blocks of size two. In each block, it first orders these two pixels and then measures the average value. The average value is placed in the middle of these two pixels. Thus, the scheme extends the block size from two to three. After applying the embedding method of Weng <i><span>et al</span></i><span>., the implantation task removed the average value from the block to reduce its size again to two. These two alive pixels are called stego pixels, which produced a stego image. A piece of state information is produced during implanting to track whether a change is happening to the block’s cover pixels. This way, after embedding in all blocks, a binary stream of state information is produced, which has later been converted to decimal values. Thus, image data were assembled in a two-dimensional array. Considering the array as another image plane, Weng </span><i><span>et al</span></i><span>.’s method is again applied to embed further to produce another stego image. Model validation ensured that the proposed method performed better than previous work </span><span>i</span><span>n this field.</span>
文摘Objective: This study aimed to evaluate the efficacy of trimetazidine on exercise capacity via a six-minute walk test in patients with ischaemic cardiomyopathy and also evaluate the effect of trimetazidine on left ventricular function via echocardiography in the same population. Methods: This prospective observational study, conducted at the National Institute of Cardiovascular Diseases in Dhaka, Bangladesh, enrolled 200 patients with ischaemic cardiomyopathy and a depressed left ventricular ejection fraction (LVEF Results: In this study (n = 200) of ischaemic cardiomyopathy patients, the mean age was 58 years, with 76% of the patients being male. All study subjects received GDMT (Guideline-Directed Medical Therapy) for angina and heart failure. Those who received the modified released form of trimetazidine developed lesions during the 1st and 2nd follow-ups, during which the LVEF, LVIDd, and six-minute walk distance significantly improved (p Conclusion: The findings of the present study demonstrated that the addition of modified-release trimetazidine to GDMT can improve exercise capacity and left ventricular function in patients with ischaemic cardiomyopathy.
