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乳腺癌患者延续护理研究现状 被引量:20
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作者 吴珂 贾会英 +3 位作者 妮娜 周梦 Nira Kumari shahi 彭歆 《护理学杂志》 CSCD 2017年第20期100-103,共4页
论述乳腺癌患者延续护理需求、干预模式和提出建议。护理需求包括后续治疗、伤口护理、功能锻炼、日常自理等;干预模式包括基于医院的延续护理(随访,成立乳腺癌患者俱乐部,制定出院计划等)、基于社区的延续护理(日间医院,家庭医院/访视... 论述乳腺癌患者延续护理需求、干预模式和提出建议。护理需求包括后续治疗、伤口护理、功能锻炼、日常自理等;干预模式包括基于医院的延续护理(随访,成立乳腺癌患者俱乐部,制定出院计划等)、基于社区的延续护理(日间医院,家庭医院/访视)及医院-社区-家庭三位一体的延续护理。建议加强延续护理相关培训,发展专业护理人员及健全相关法规制度,以促进乳腺癌患者延续护理体系的健全与发展。 展开更多
关键词 乳腺癌 延续护理 综述文献
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社区护理人员灾害准备的研究进展 被引量:15
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作者 周梦 妮娜 +3 位作者 贾会英 吴珂 Nira Kumari shahi 彭歆 《护理学杂志》 CSCD 北大核心 2018年第2期99-102,共4页
对国内外社区护理人员灾害准备模式、存在的问题、影响因素、培训现状及测量工具进行综述。提出应建立完善的社区护理人员灾害准备培训体系,建立适合我国国情的社区护理人员灾害应对准备模式并建立社区护理人员灾害准备测量工具的区域... 对国内外社区护理人员灾害准备模式、存在的问题、影响因素、培训现状及测量工具进行综述。提出应建立完善的社区护理人员灾害准备培训体系,建立适合我国国情的社区护理人员灾害应对准备模式并建立社区护理人员灾害准备测量工具的区域性常模,旨在为今后提高社区护理人员的灾害准备度提供参考依据。 展开更多
关键词 社区护理人员 灾害 灾害准备 灾害应对能力 社区护理 灾害医疗救援 综述文献
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多学科乳腺癌团队在乳腺癌患者决策辅助中的应用研究进展 被引量:11
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作者 韦文棋 吴珂 +5 位作者 贾会英 周梦 妮娜 王粲霏 Nira Kumari shahi 彭歆 《解放军护理杂志》 CSCD 北大核心 2018年第19期48-51,63,共5页
乳腺癌是全世界女性最常见的恶性肿瘤之一,随着乳腺癌诊断、分期及管理的演变和完善,其治疗方案变得越来越复杂.由于存在多种有效治疗方案,有学者认为在遵循法律和道德的原则下,尊重患者的自主权至关重要,因此,有必要让乳腺癌患者参与... 乳腺癌是全世界女性最常见的恶性肿瘤之一,随着乳腺癌诊断、分期及管理的演变和完善,其治疗方案变得越来越复杂.由于存在多种有效治疗方案,有学者认为在遵循法律和道德的原则下,尊重患者的自主权至关重要,因此,有必要让乳腺癌患者参与到治疗决策中. 展开更多
关键词 乳腺癌患者 决策辅助 应用 治疗方案 恶性肿瘤 尊重患者 患者参与 自主权
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Inhibition of pacemaker activity in interstitial cells of Cajal by LPS via NF-κB and MAP kinase 被引量:10
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作者 Dong Chuan Zuo Seok Choi +7 位作者 Pawan Kumar shahi Man Yoo Kim Chan Guk Park Young Dae Kim Jun Lee In Yeoup Chang Insuk So Jae Yeoul Jun 《World Journal of Gastroenterology》 SCIE CAS 2013年第8期1210-1218,共9页
AIM:To investigate lipopolysaccharide(LPS) related signal transduction in interstitial cells of Cajal(ICCs) from mouse small intestine.METHODS:For this study,primary culture of ICCs was prepared from the small intesti... AIM:To investigate lipopolysaccharide(LPS) related signal transduction in interstitial cells of Cajal(ICCs) from mouse small intestine.METHODS:For this study,primary culture of ICCs was prepared from the small intestine of the mouse.LPS was treated to the cells prior to measurement of the membrane currents by using whole-cell patch clamp technique.Immunocytochemistry was used to examine the expression of the proteins in ICCs.RESULTS:LPS suppressed the pacemaker currents of ICCs and this could be blocked by AH6809,a prostaglandin E2-EP2 receptor antagonist or NG-Nitro-Larginine Methyl Ester,an inhibitor of nitric oxide(NO) synthase.Toll-like receptor 4,inducible NO synthase or cyclooxygenase-2 immunoreactivity by specific antibodies was detected on ICCs.Catalase(antioxidant agent) had no action on LPS-induced action in ICCs.LPS actions were blocked by nuclear factor kB(NF-kB) inhibitor,actinomycin D(a gene transcription inhibitor),PD 98059(a p42/44 mitogen-activated protein kinases inhibitor) or SB 203580 [a p38 mitogen-activated protein kinases(MAPK) inhibitor].SB 203580 also blocked the prostaglandin E2-induced action on pacemaker currents in ICCs but not NO.CONCLUSION:LPS inhibit the pacemaker currents in ICCs via prostaglandin E2-and NO-dependent mechanism through toll-like receptor 4 and suggest that MAPK and NF-kB are implicated in these actions. 展开更多
关键词 INTERSTITIAL cells of CAJAL LIPOPOLYSACCHARIDE MITOGEN-ACTIVATED protein KINASES Nuclear factor kB Small INTESTINE
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Evaluation of Seismic Behavior and Earth’s Surface Acceleration, by Interaction of Tunnels with Different Shapes and Different Types of Soils 被引量:3
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作者 Arash Rostami Morteza Askari Ziarati +1 位作者 Bahman shahi Saman Jahani 《Open Journal of Civil Engineering》 2016年第2期242-253,共12页
With the increasing population and the consequent needs for transport facilities, the construction of tunnels in urban environments is fast growing. Tunneling at each depth of the soil, causes changes in the earth’s ... With the increasing population and the consequent needs for transport facilities, the construction of tunnels in urban environments is fast growing. Tunneling at each depth of the soil, causes changes in the earth’s surface;this is more important about urban areas tunnels, especially when crossing the residential areas, so having knowledge of their performance is really important. Some of the consequences of underground tunneling are earth surface moving around the tunnel, movement of tunnel’s surrounding and changes in earthquake acceleration. The performance and behavior of underground structures have been studied by numerous researchers, but the effect of tunneling on earthquake records and its effects on aboveground structures have been getting less attention. The current article will try to study and examine the changes in seismic velocity at ground level, structural response spectrum, and Fourier spectrum with digging a circular tunnel. The results show that digging a circular tunnel at ground level will cause a change in the earthquake records profile. 展开更多
关键词 TUNNEL Earthquake Records Abaqus Seismosignal
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Investigating Effect of Tunnel Gate Shapes with Similar Cross Section on Inserted Forces on Its Coverage and Soil Surface Settlement 被引量:2
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作者 Arash Rostami Nima Asghari +2 位作者 Morteza Askari Ziarati Saman Jahani Bahman shahi 《Open Journal of Civil Engineering》 2016年第3期358-369,共12页
According to technology development and relative facilitation in digging and underground structures, ways, highways, all types of tunnels, underground train network, and other underground settle, storage are number of... According to technology development and relative facilitation in digging and underground structures, ways, highways, all types of tunnels, underground train network, and other underground settle, storage are number of structure built and developed in advanced countries. In most situation, tunnel digging operations are done years after its construction or are not recorded in new structures regulations;therefore, this research investigates soil settlement and inserting force to tunnel coverage by limiting studies about effects of tunnel shapes on soil settlement using Plaxis, Seismo Signal, and Seismo Aspect. This study shows that rectangular tunnel has the most settlement in soil surface and circular tunnel has the least settlement but horseshoe tunnel has similar behavior to circular tunnel;however, earth subsidence level by digging this tunnel is more than circular tunnel. In addition, sectional shape has direct effect on inserting forces on tunnel coverage. 展开更多
关键词 Soil Settlement Rectangular Tunnel Circular Tunnel Horseshoe Tunnel Concrete Coverage
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Biochar-based bioenergy and its environmental impact in Northwestern Ontario Canada: A review 被引量:5
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作者 Krish Homagain Chander shahi +1 位作者 Nancy Luckai Mahadev Sharma 《Journal of Forestry Research》 SCIE CAS CSCD 2014年第4期737-748,共12页
Biochar is normally produced as a by-product of bioenergy. However, if biochar is produced as a co-product with bioenergy from sustainably managed forests and used for soil amendment, it could pro- vide a carbon neutr... Biochar is normally produced as a by-product of bioenergy. However, if biochar is produced as a co-product with bioenergy from sustainably managed forests and used for soil amendment, it could pro- vide a carbon neutral or even carbon negative solution for current envi- ronmental degradation problems. In this paper, we present a comprehen- sive review of biochar production as a co-product of bioenergy and its implications. We focus on biochar production with reference to biomass availability and sustainability and on bioehar utilization for its soil amendment and greenhouse gas emissions reduction properties. Past studies confirm that northwestern Ontario has a sustainable and sufficient supply of biomass feedstock that can be used to produce bioenergy, with biochar as a co-product that can replace fossil fuel consumption, increase soil productivity and sequester carbon in the long run. For the next step, we recommend that comprehensive life cycle assessment of bio- char-based bioenergy production, from raw material collection to bioehar application, with an extensive economic assessment is necessary for making this technology commercially viable in northwestern Ontario. 展开更多
关键词 biomass life cycle assessment LCA C02 carbon sequestra-tion greenhouse gas emissions soil amendment
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尼泊尔卡纳利省药用和芳香植物对国内生产总值的贡献
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作者 Kamal Raj ARYAL Anup GURUNG +6 位作者 Prabin PAUDEL Rajendra Kumar BASUKALA Shiva PARIYAR Arjun THAPA Hikmat Kumar shahi Ganga SHAH Saroj PANTHI 《Journal of Resources and Ecology》 CSCD 2023年第5期1104-1112,共9页
自古以来,药用和芳香植物(MAPs)在尼泊尔就被广泛种植并用于医疗保健和治疗实践,在尼泊尔社区拥有很重要的文化、宗教和经济价值。近年来,MAPs部门在尼泊尔尤其是喜马拉雅山区是一个不断发展的商业部门,为低收入人群提供生计机会。本研... 自古以来,药用和芳香植物(MAPs)在尼泊尔就被广泛种植并用于医疗保健和治疗实践,在尼泊尔社区拥有很重要的文化、宗教和经济价值。近年来,MAPs部门在尼泊尔尤其是喜马拉雅山区是一个不断发展的商业部门,为低收入人群提供生计机会。本研究评估了MAPs对尼泊尔卡纳利省国内生产总值(GDP)的贡献。卡纳利省共鉴定出58种MAPs。人们发现,这些一年生、两双年生和多年生植物的各个部分都可被用作药物、香水和食品。在2019/2020财年,卡纳利省的MAP产生的经济产出为1607.38亿尼泊尔卢比(13.9亿美元),相当于卡纳利省GDP的1.03%,相当于全国GDP的0.02%。然而,调查结果显示,由于未纳入药用植物的民族植物学用途,目前的GDP估算低估了MAPs部门对国家GDP的贡献,如果将人们从这一部门获得的所有收入和环境利益都体现在国民账户体系中,进行估价和记录,那么MAPs的GDP将远远高于本研究中的估算值。我们得出结论,MAPs对卡纳利省和尼泊尔的GDP有合理的贡献。 展开更多
关键词 非木材林产品 税费 贸易 尼泊尔
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Population genetic insights into the conservation of common walnut(Juglans regia)in Central Asia
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作者 Linjiang Ye Robabeh shahi Shavvon +7 位作者 Hailing Qi Hongyu Wu Pengzhen Fan Mohammad Nasir Shalizi Safiullah Khurram Mamadzhanov Davletbek Yerlan Turuspekov Jie Liu 《Plant Diversity》 SCIE CAS CSCD 2024年第5期600-610,共11页
The common walnut(Juglans regia)is one of the most economically important nut trees cultivated worldwide.Despite its importance,no comprehensive evaluation of walnut tree population genetics has been undertaken across... The common walnut(Juglans regia)is one of the most economically important nut trees cultivated worldwide.Despite its importance,no comprehensive evaluation of walnut tree population genetics has been undertaken across the range where it originated,Central Asia.In this study,we investigated the genetic diversity and population structure of 1082 individuals from 46 populations across Central Asia.We found moderate genetic diversity of J.regia across Central Asia,with 46 populations clustered into three groups with a weak relationship between genetic and geographic distance.Our findings reveal that the western Himalaya might be the core region of common walnut genetic diversity in Central Asia and that,except for two populations in Gongliu Wild Walnut Valley,humans might have introduced walnut populations to Xinjiang,China.The observed distribution of the genetic landscape has probably been affected by historical climate fluctuation,breeding system,and prolonged anthropogenic activity.We propose the conservation of the core genetic diversity resources in the western Himalaya and pay special attention to populations from Gongliu in Xinjiang.These findings enhance our understanding of the genetic variation throughout the distribution range of J.regia in Central Asia,which will provide a key prerequisite for evidence-based conservation and management. 展开更多
关键词 Central Asia Genetic diversity Germplasm management Gongliu wild walnut valley Juglans regia Western Himalaya
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Named Entity Recognition for Nepali Text Using Support Vector Machines 被引量:3
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作者 Surya Bahadur Bam Tej Bahadur shahi 《Intelligent Information Management》 2014年第2期21-29,共9页
Named Entity Recognition aims to identify and to classify rigid designators in text such as proper names, biological species, and temporal expressions into some predefined categories. There has been growing interest i... Named Entity Recognition aims to identify and to classify rigid designators in text such as proper names, biological species, and temporal expressions into some predefined categories. There has been growing interest in this field of research since the early 1990s. Named Entity Recognition has a vital role in different fields of natural language processing such as Machine Translation, Information Extraction, Question Answering System and various other fields. In this paper, Named Entity Recognition for Nepali text, based on the Support Vector Machine (SVM) is presented which is one of machine learning approaches for the classification task. A set of features are extracted from training data set. Accuracy and efficiency of SVM classifier are analyzed in three different sizes of training data set. Recognition systems are tested with ten datasets for Nepali text. The strength of this work is the efficient feature extraction and the comprehensive recognition techniques. The Support Vector Machine based Named Entity Recognition is limited to use a certain set of features and it uses a small dictionary which affects its performance. The learning performance of recognition system is observed. It is found that system can learn well from the small set of training data and increase the rate of learning on the increment of training size. 展开更多
关键词 Support VECTOR MACHINE Named ENTITY Recognition MACHINE Learning Classification Nepali LANGUAGE TEXT
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Life cycle environmental impact assessment of biochar-based bioenergy production and utilization in Northwestern Ontario,Canada 被引量:2
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作者 Krish Homagain Chander shahi +1 位作者 Nancy Luckai Mahadev Sharma 《Journal of Forestry Research》 SCIE CAS CSCD 2015年第4期799-809,共11页
Biochar-based bioenergy production and sub- sequent land application of biochar can reduce greenhouse gas emissions by fixing atmospheric carbon into the soil for a long period of time. A thorough life cycle assessmen... Biochar-based bioenergy production and sub- sequent land application of biochar can reduce greenhouse gas emissions by fixing atmospheric carbon into the soil for a long period of time. A thorough life cycle assessment of biochar-based bioenergy production and biochar land application in Northwestern Ontario is conducted using SimaPro Ver. 8.1. The results of energy consumption and potential environmental impact of biochar-based bioenergy production system are compared with those of conventional coal-based system. Results show that biocbar land application consumes 4847.61 MJ per tonne dry feedstock more energy than conventional system, but reduces the GHG emissions by 68.19 kg CO2e per tonne of dry feed- stock in its life cycle. Biochar land application improves ecosystem quality by 18 %, reduces climate change by 15 %, and resource use by 13 % but may adversely impact on human health by increasing disability adjusted life years by 1.7 % if biomass availability is low to medium. Replacing fossil fuel with woody biomass has a positiveimpact on the environment, as one tonne of dry biomass feedstock when converted to biochar reduces up to 38 kg CO2e with biochar land application despite using more energy. These results will help understand a comprehensive picture of the new interventions in forestry businesses, which are promoting biochar-based bioenergy production. 展开更多
关键词 Woody biomass Carbon sequestration Environmental impact assessment Greenhouse gasemissions Life cycle analysis Soil amendment
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Mobile SMS Spam Filtering for Nepali Text Using Naive Bayesian and Support Vector Machine 被引量:2
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作者 Tej Bahadur shahi Abhimanu Yadav 《International Journal of Intelligence Science》 2014年第1期24-28,共5页
Spam is a universal problem with which everyone is familiar. A number of approaches are used for Spam filtering. The most common filtering technique is content-based filtering which uses the actual text of message to ... Spam is a universal problem with which everyone is familiar. A number of approaches are used for Spam filtering. The most common filtering technique is content-based filtering which uses the actual text of message to determine whether it is Spam or not. The content is very dynamic and it is very challenging to represent all information in a mathematical model of classification. For instance, in content-based Spam filtering, the characteristics used by the filter to identify Spam message are constantly changing over time. Na?ve Bayes method represents the changing nature of message using probability theory and support vector machine (SVM) represents those using different features. These two methods of classification are efficient in different domains and the case of Nepali SMS or Text classification has not yet been in consideration;these two methods do not consider the issue and it is interesting to find out the performance of both the methods in the problem of Nepali Text classification. In this paper, the Na?ve Bayes and SVM-based classification techniques are implemented to classify the Nepali SMS as Spam and non-Spam. An empirical analysis for various text cases has been done to evaluate accuracy measure of the classification methodologies used in this study. And, it is found to be 87.15% accurate in SVM and 92.74% accurate in the case of Na?ve Bayes. 展开更多
关键词 SMS Spam Filtering Classification Support Vector Machine Naive Bayes PREPROCESSING Feature Extraction Nepali SMS Datasets
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Changes in soil biochemical properties following replacement of Banj oak forest with Chir pine in Central Himalaya,India 被引量:2
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作者 Vijyeta Manral Kiran Bargali +1 位作者 S.S.Bargali Charu shahi 《Ecological Processes》 SCIE EI 2020年第1期346-354,共9页
Introduction:In Central Himalaya,anthropogenic activities have led to the widespread replacement of Banj oak(Quercus leucotrichophora)forest by Chir pine(Pinus roxburghii)for decades.This study was conducted to determ... Introduction:In Central Himalaya,anthropogenic activities have led to the widespread replacement of Banj oak(Quercus leucotrichophora)forest by Chir pine(Pinus roxburghii)for decades.This study was conducted to determine how natural Banj oak,Chir pine,and mixed oak-pine forest would differ in soil microbial biomass and soil nutrients.Soil microbial biomass nitrogen(SMBN)and phosphorus(SMBP),soil organic carbon(SOC)total nitrogen(TN),and total phosphorus(TP)in the 0 to 15 cm soil layer were investigated in the Central Himalayan region in the stands of Banj oak,mixed oak-pine,and Chir pine forest.Results:The SMBN and SMBP were significantly higher in Banj oak and mixed oak-pine forest as compared to Chir pine forest.The ratios of SMBN to TN(SMBN/TN)and SMBP to TP(SMBP/TP)were significantly higher in the Chir pine forest,indicating that in this forest,the proportion of microbial biomass N and P to total soil N and P was higher as compared to Banj oak forest.A similar pattern of variation was found in relation to season across the forests,all with an apparent peak in the rainy season.Conclusion:These results indicate that low microbial biomass N and P may be one of the reasons to create a nutrient poor site in Chir pine forest.The collection of pine litter by local people also impairs the return of nutrients to the soil and makes it difficult for Banj oak to re-invade areas occupied by Chir pine.This calls for cautions in large-scale conversions of the Banj oak forests to coniferous plantations as a forest management practice on concerns of sustaining soil productivity. 展开更多
关键词 Soil microbial biomass nitrogen(SMBN) soil microbial biomass phosphorus(SMBP) Forest types Chloroform fumigation and extraction method(CFE) ALTITUDE
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An application of data envelopment analysis to investigate the efficiency of lumber industry in northwestern Ontario,Canada 被引量:1
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作者 Thakur Prasad Upadhyay Chander shahi Mathew Leitch Reino Pulkki 《Journal of Forestry Research》 SCIE CAS CSCD 2012年第4期675-684,共10页
This study aims at exploring the technical efficiency of lum- ber industry in northwestern Ontario, Canada using data envelopment analysis (DEA). The DEA model analyzes relative technical efficiency of lumber mills ... This study aims at exploring the technical efficiency of lum- ber industry in northwestern Ontario, Canada using data envelopment analysis (DEA). The DEA model analyzes relative technical efficiency of lumber mills with disproportionate inputs and outputs by dividing the 10- year time series data, for inputs and outputs of 24 lumber mills, over two periods (1999-2003 and 2004-2008). Four inputs, namely, material (log volume), labour (man-hours), two types of energy (hog-fuel and electric- ity), and one output (lumber volume) are used in this study. The trend analysis shows an annual reduction of 10%, 13% and 13% for lumber output, log consumption (input) and number of employees, respectively, during the period 1999-2008. The results from DEA with two scenarios with energy inputs and without energy inputs, for the two periods are found to be mixed and interesting. While some mills have improved their performance in terms of best use of available scarce inputs in the second period, some have shown negative per cent change in efficiency. In the with energy input and the without energy input scenario, some of the mills show a reduction in efficiency in the second period from the first period, with the highest estimated reductions of-13.9% and -47.6%, respectively. A possible explanation for these negative performances of mills in the latter period is the decline in production in the second period compared to the first period, where these mills were not able to adjust their inputs (mostly labour) as proportional lay-offs might not have been possible. These results provide policy makers and industry stakeholders with an improved understanding of the trends of efficiency and employ- ment as well as reallocation opportunities of future inputs in order to increase benefits from this sector. 展开更多
关键词 allocative efficiency forest products industry MODELLING production inputs technical efficiency
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Classification of oil palm female inflorescences anthesis stages using machine learning approaches 被引量:1
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作者 Mamehgol Yousefi D.B A.S.Mohd Rafie +4 位作者 Samsuzana Abd Aziz Syaril Azrad Mohamed Mazmira Mohd Masri Ahmad shahi O.F.Marzuki 《Information Processing in Agriculture》 EI 2021年第4期537-549,共13页
Prediction of pollination stages in oil palm plantations is an important research area in precision agriculture.Oil palm is known as the most efficient commercial crop with the capacity to fulfill the growing global d... Prediction of pollination stages in oil palm plantations is an important research area in precision agriculture.Oil palm is known as the most efficient commercial crop with the capacity to fulfill the growing global demand for vegetable oil consumption.However,oil palm production dependence on pollination is experiencing issues with decreasing the actual yield.Consequently,alternative methods in commercial plantations such as humanassisted pollination and recently Wireless Sensor Network(WSN)have been deployed despite their high economic costs due to labor requirements.Oil palm assisted pollination requires precision,inspection,traceability,and validation processes in the field.Currently,all these processes are performed by humans that can be associated with false assumptions,uncertainty,and pollination latency.Therefore,Machine Learning(ML)approaches as a subset of the Artificial Intelligence(AI)domain provides efficient,cost-effective,and non-destructive solutions to determine these reproductive stages for future autonomous pollination system.Our goal was to reduce the variability of worker’s performance in oil palms,using ML algorithms to make expert decisions and reduce the risk related to a transient workforce.This comparative empirical study examined and compared the performance of the Random Forest(RF)against k Nearest Neighbor(kNN)and Support Vector Machine(SVM)for classification of oil palm pre-anthesis and anthesis stages,dividing into four classes(1,2,3,and 4).These models were tested using thermal features(endogenous)individually and in combination with meteorological variables(exogenous).The performance of models is evaluated with specific measures of performance,such as overall user’s and producer’s accuracies and F-measure values derived from the confusion matrix.The results showed that the RF model produced better results with regard to average Fmeasure(88.6%,71.83%),producer’s accuracies(88.70%,71.35%),and user’s accuracies(88.27%,72.36%)on test sets using exogenous+exogenous and endoge 展开更多
关键词 Oil palm POLLINATION Anthesis stage Machine Learning CLASSIFICATION
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人巨细胞病毒对自然杀伤细胞表面自然杀伤细胞2族成员受体表达的影响 被引量:1
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作者 顾绍庆 李文静 韦苇 马晓蒙 Rupa Rana shahi 赵媛 《中华传染病杂志》 CAS CSCD 北大核心 2014年第4期199-203,共5页
目的 观察人CMV对NK细胞表面自然杀伤细胞2族(NKG2)成员,包括NKG2A、NKG2C和NKG2D表达的影响.方法 免疫磁珠法提取健康人PBMC中的NK细胞,与感染人CMV的人胚肺成纤维细胞(HELF)共培养24 h;同时设未感染CMV的HELF与NK细胞共培养组和N... 目的 观察人CMV对NK细胞表面自然杀伤细胞2族(NKG2)成员,包括NKG2A、NKG2C和NKG2D表达的影响.方法 免疫磁珠法提取健康人PBMC中的NK细胞,与感染人CMV的人胚肺成纤维细胞(HELF)共培养24 h;同时设未感染CMV的HELF与NK细胞共培养组和NK细胞组.流式细胞技术检测各组NK细胞NKG2A、NKG2C和NKG2D的表达.组间比较采用Wilcoxon检验.结果 感染CMV的HELF+ NK细胞共培养组NKG2C和NKG2D表达水平为34.26%±7.99%和24.94%±5.24%,高于HELF+NK细胞共培养组的26.31%±6.41%(Z=-3.285,P=0.001)和20.02%±6.80%(Z=-3.285,P=0.001),也高于NK细胞组的25.78%±6.62%(Z=-3.211,P=0.001)和20.12%±6.75%(Z=-3.285,P=0.001);而HELF+NK细胞共培养组与NK细胞组比较差异无统计学意义(均P>0.05).NKG2A在各组间表达差异亦无统计学意义(均P>0.05).感染CMV的HELF+NK细胞共培养组NKG2A+ NKG2C-为2.99%±2.62%,NKG2A+NKG2D-为6.13%±2.44%,NKG2C+ NKG2A-为26.62%±7.63%,NKG2D+ NKG2A为20.44%±5.68%,而HELF+ NK细胞组分别为4.44%±4.25%(Z=-2.240,P=0.025)、6.99%±2.33%(Z=-2.053,P=0.040)、19.52%±6.80%(Z=-2.800,P=0.005)和15.78%±7.48%(Z=-2.875,P=0.004).NKG2A+ NKG2C+和NKG2A+ NKG2D+在各组间比较差异均无统计学意义(均P>0.05).结论 人CMV感染可改变NK细胞受体的表达量,使NKG2C、NKG2D转导的活化性信号增强,NKG2A转导的抑制性信号减弱. 展开更多
关键词 巨细胞病毒 杀伤细胞 天然 受体 细胞表面
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Novelty Design in Gain Flattening Filter of ASE Source Based on Fat Ultra-Long Period Fiber Grating 被引量:1
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作者 Fereshteh Mohammadi NAFCHI Sharifeh shahi +2 位作者 Mohammad Taha SHAFFAATIFAR Mohammad KANANI Hossein NOORMOHAMMADI 《Photonic Sensors》 SCIE EI CAS CSCD 2016年第3期243-248,共6页
A new type of gain flattening filter for amplified spontaneous emission (ASE) source based on erbium doped fiber (EDF) is proposed and demonstrated by fabricating and writing two series ultra-long period fiber gra... A new type of gain flattening filter for amplified spontaneous emission (ASE) source based on erbium doped fiber (EDF) is proposed and demonstrated by fabricating and writing two series ultra-long period fiber grating (ULPFG) on single mode fiber (SMF-28). The novelty method in this research is based on writing the two ULPFGs as fat gratings. The LPG is written by a simple and available arc-discharge method. The pump power based on single-pass backward pump configuration is around 100mW, and the average wavelength is near to 974nm. The gain flattening profile is obtained by 3.4 (±1.7)dB ripple in the wavelength range between 1524nm and 1565nm with 41-nm band width. 展开更多
关键词 Amplified spontaneous emission (ASE) source erbium-doped fiber amplifier (EDFA) gain flatteningfilter long-period fiber grating (LPFG)
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Life cycle cost and economic assessment of biochar-based bioenergy production and biochar land application in Northwestern Ontario, Canada 被引量:1
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作者 Krish Homagain Chander shahi +1 位作者 Nancy Luckai Mahadev Sharma 《Forest Ecosystems》 SCIE CSCD 2017年第1期12-21,共10页
Background: Replacement of fossil fuel based energy with biochar-based bioenergy production can help reduce greenhouse gas emissions while mitigating the adverse impacts of climate change and global warming. However,... Background: Replacement of fossil fuel based energy with biochar-based bioenergy production can help reduce greenhouse gas emissions while mitigating the adverse impacts of climate change and global warming. However, the production of biochar-based bioenergy depends on a sustainable supply of biomass. Although, Northwestern Ontario has a rich and sustainable supply of woody biomass, a comprehensive life cycle cost and economic assessment of biochar-based bioenergy production technology has not been done so far in the region. Methods: In this paper, we conducted a thorough life cycle cost assessment (LCCA) of biochar-based bioenergy production and its land application under four different scenarios: 1) biochar production with low feedstock availability; 2) biochar production with high feedstock availability; 3) biochar production with low feedstock availability and its land application; and 4) biochar production with high feedstock availability and its land applicationusing SimaPro, EIOLCA software and spreadsheet modeling. Based on the LCCA results, we further conducted an economic assessment for the break-even and viability of this technology over the project period. Results: It was found that the economic viability of biochar-based bioenergy production system within the life cycle analysis system boundary based on study assumptions is directly dependent on costs of pyrolysis, feedstock processing (drying, grinding and pelletization) and collection on site and the value of total carbon offset provided by the system. Sensitivity analysis of transportation distance and different values of C offset showed that the system is profitable in case of high biomass availability within 200 km and when the cost of carbon sequestration exceeds CAD S60 per tonne of equivalent carbon (CO2e). Conclusions: Biochar-based bioenergy system is economically viable when life cycle costs and environmental assumptions are accounted for. This study provides a medium scale slow-pyrolysis plant scenario and we 展开更多
关键词 LCA LCCA SimaPro BIOCHAR Biomass PYROLYSIS BIOENERGY Wood Pellets
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Isolation and characterization of endosulfan-degrading bacteria from contaminated agriculture soils
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作者 Mehdi Hassanshahian Zahra shahi 《Journal of Coastal Life Medicine》 2016年第4期290-294,共5页
Objective:To isolate and characterize endosulfan-degrading bacteria from Kerman pistachio orchards.Methods:Endosulfan-degrading bacteria were enriched in Bushnell-Hass medium.Identification and sequencing of prevalent... Objective:To isolate and characterize endosulfan-degrading bacteria from Kerman pistachio orchards.Methods:Endosulfan-degrading bacteria were enriched in Bushnell-Hass medium.Identification and sequencing of prevalent degrading strains was performed by using PCR based on amplifying 16S rDNA.Results:The results showed that the soils of pistachio orchards have some degrading bacteria that are suitable for elimination of endosulfan from soils and the environment.Four endosulfandegrading bacteria strains belong to Achromobacter xylosoxidans(strain EN3),Pseudomonas azotoformans(strain EN4),Pseudomonas brassicacearum(strain EN7)and Pseudomonas thivervalensis(strain EN8),respectively.The best degrading strain(EN7),up to 100 mg/L,illustrated a good growth,whereas the growth was reduced in concentration higher than 100 mg/L.The results of gas chromatography confirmed the decomposition of organic pesticide by degrading-bacteria.Conclusions:By using these strains and other biological reclamation methods we can eliminate bio-environmental problems. 展开更多
关键词 Agricultural pesticide Degrading bacteria ENDOSULFAN KERMAN
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Assessment Capability Forest Regeneration in Different Geographical Aspects Approach Landscape Ecology
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作者 Arash Karami Saeed Karimi Elham shahi 《Open Journal of Ecology》 2017年第9期535-553,共19页
In order to determine the relationship between physiographical factors and regeneration changes in forests, and to improve and model natural regeneration status, Gorazbon district in Kheyrod Forest was selected for th... In order to determine the relationship between physiographical factors and regeneration changes in forests, and to improve and model natural regeneration status, Gorazbon district in Kheyrod Forest was selected for the study. All available regeneration patches in the area were selected. To achieve spatial structure and quantify metrics related to regeneration patches, the analysis of landscape metrics was used. The results show that 692 regeneration patches were identified at the level of different directions. LAND Metric show the most regeneration percent is related to the western (9%), southern (8.66%), flat areas (8.33%), northern (5.68%) and eastern (4.73%), respectively. In total, the patch coverage level percentage was calculated in the landscape (8.31%). The results related to patch shape metric show that most shapes of patches follow polygon structures and do not have fixed shapes. Results related to the average area of the patch metric show that the average level of patches is between 4 and 5 R. The maximum and minimum distance between patches was observed in the survey between 39 and 520 m respectively. According to the results of the distance average between patch metric, the distribution of patches is random in the southern and western directions, flat areas and pile, but it is uniform in northern directions. It should be noted that the distribution and structure of patches in the northern directions has a better distribution and homogeneity than the other directions. Its canals are used as a natural regeneration model to follow the natural phenomena in forest sustainable management. 展开更多
关键词 GEOGRAPHICAL DIRECTIONS Natural Distribution Kheyrod FOREST Metrics LANDSCAPE
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