Purpose: To evaluate the use of releasable sutures in filtration surgery by comparing the results and the rate of post-operative complications in eyes which underwent filtration surgery with and without releasable sut...Purpose: To evaluate the use of releasable sutures in filtration surgery by comparing the results and the rate of post-operative complications in eyes which underwent filtration surgery with and without releasable sutures. Methods: A retrospective evaluation of 74 eyes with glaucoma (COAG, CNAG, PXFG) of 74 patients who underwent filtration surgery in our department during 1999. All the patients included in the study had 6-12展开更多
Aims: To report the experience with trabeculectomy augmented with mitomycin C and 5- fluorouracil for the treatment of paediatric glaucoma. Methods: Retrospective, interventional case series design was used. The sampl...Aims: To report the experience with trabeculectomy augmented with mitomycin C and 5- fluorouracil for the treatment of paediatric glaucoma. Methods: Retrospective, interventional case series design was used. The sample included 17 children (29 eyes) with primary (19 eyes) or secondary (10 eyes) glaucoma who were treated with augmented trabeculectomy as the primary procedure between 1990 and 2002. Data were collected on age and family history, preoperative and end of follow up intraocular pressure, cup/disc ratio (evaluated by drawing), visual acuity, complications, and post-surgery treatment. Results: Patient age at surgery ranged from 1 month to 8 years; most patients (n=14, 82.3% ) were aged less than 1 year (range 1 month-8 months, mean 3.95 (SD 2.56) months); three patients (17.7% ) were aged3, 5, and 8 years. The duration of follow up was 3- 120 months (mean 46 months). Intraocular pressure significantly improved from 21 mm Hg to 60 mm Hg (mean33.1 (10) mm Hg) before surgery to 6- 26 mm Hg (mean 17.1 (6) mm Hg) after, (P < 0.0001). There was no significant change in cup/disc ratio: 0.1- 0.8 (mean 0.42 (0.26)) before and 0.1- 1.0 (mean 0.511 (0.27)) after (P=0.45). In 22 eyes (75.8% ), intraocular pressure was controlled at less than 20 mm Hg and the cup/disc ratio remained stable or improved. The life table success rate for intraocular pressure control remained stable at 86% at the 12, 24, and 36 months and after 48 months decreased to 53% . There was no significant difference in the life table results between primary and secondary glau coma. 14 eyes (48.2% ) had a visual acuity better than 20/120 by the end of follow up. Repeated surgery was necessary in eight eyes (27.5% ), and additional antiglaucoma treatment in 13 (44.8% ). Complications included retinal detachment 1 year after surgery, choroidal detachment, and blebitis (one eye each). Conclusions: Augmented trabeculectomy with mitomycin C and 5- fluorouracil may serve as the primary procedure in a selected group of paediatric patients with glaucoma.展开更多
Objective To examine the reliability of Swedish Interactive Thresholding Algor ithm Fast (SITA Fast) visual fields (VFs) in prepubertal idiopathic intracranial hypertension (IIH) and to compare whether age, gender, or...Objective To examine the reliability of Swedish Interactive Thresholding Algor ithm Fast (SITA Fast) visual fields (VFs) in prepubertal idiopathic intracranial hypertension (IIH) and to compare whether age, gender, or severity of visual outcome influenced the reliability o f VF tests. Design Prospective, longitudinal cohort study. Participants Twenty- six prepubertal children (< 11 years of age; mean age, 7.2 years) with IIH. Test ing Children were prospectively followed up using a childoriented program, which included SITA Fast VF tests. Age, gender, and severity of visual outcome were c orrelated with reliability of performance on SITA Fast VFs using a 1-way analys is of variance, point-biserial correlation, and the chi-square test for indepe ndence of observation. Main outcome measures Statistical analyses results that c orrelated the reliability of SITA Fast VFs with age, gender, and visual outcome. Results Three children were treated at the age of 2 years and were unable to pe rform automated VF tests. Four children were treated at the age of 4 years, 3 of whom were able to perform repeatable reliable SITA Fast VF tests. Forty-two ey es of 21 children had an average SIT AFast test time of 4.5 minutes for each eye , compared with 8 minutes using the Fastpac strategy. Age was not associated wit h reliability scores of SITA Fast tests (F=0.971, not significant ns). Gender did not influence the reliability of SITA Fast VF tests (chi-square(1)=0.669, n s), nor did severity of visual outcome (chi-square(2)=3.348, ns). Visual defici ts were observed in 55%of patients at presentation and in 27%of patients after resolution of papilledema. Conclusions The SITA Fast VF tests can be performed from age 4 years and offer a reliable method for shortening test time. A child- oriented follow-up program, which entails a shortened testing time, may improve outcome in prepubertal IIH.展开更多
The purpose of this study was to evaluate the characteristics of automated perimetry exams at a large diagnostic institute. We describe the model of operation of this institue that provides greater than 80% of the vis...The purpose of this study was to evaluate the characteristics of automated perimetry exams at a large diagnostic institute. We describe the model of operation of this institue that provides greater than 80% of the visual field examinations, with interpretation, for a population of 2 million people. The institute展开更多
Objective: This study was undertaken to compare the effect of antenatal corticosteroid therapy on the risk for severe intraventricular hemorrhage (IVH grade III- IV) in pretermsingleton and multiple very low birth wei...Objective: This study was undertaken to compare the effect of antenatal corticosteroid therapy on the risk for severe intraventricular hemorrhage (IVH grade III- IV) in pretermsingleton and multiple very low birth weight (VLBW) infants. Study design:The occurrence of severe IVH was recorded in 5022 singleton,2032 twin, and 582 triplet infants, delivered at 24 to 32 weeks gestation, registered in the Israeli National VLBW infant database. Antenatal corticosteroid therapy was defined as complete,partial, or none. Results: The incidence of IVH grade Ⅲ - IV ranged from 6.8% among singletons receiving complete course to 29.3% in triplets without antenatal corticosteroid treatment.Complete treatment significantly reduced the incidence of IVH in all plurality groups. The adjusted risk for IVH among multiple infants who received a complete course compared with singletons was not significantly different, odds ratio (OR) 1.3,95% CI 1.0- 1.7 for twins and OR 1.5, 95% CI 0.9- 2.3 for triplets.Conclusion: Complete course of antenatal corticosteroid therapy was independently associated with decreased risk for severe IVH in singleton and in multiple preterm VLBW infants.展开更多
文摘Purpose: To evaluate the use of releasable sutures in filtration surgery by comparing the results and the rate of post-operative complications in eyes which underwent filtration surgery with and without releasable sutures. Methods: A retrospective evaluation of 74 eyes with glaucoma (COAG, CNAG, PXFG) of 74 patients who underwent filtration surgery in our department during 1999. All the patients included in the study had 6-12
文摘Aims: To report the experience with trabeculectomy augmented with mitomycin C and 5- fluorouracil for the treatment of paediatric glaucoma. Methods: Retrospective, interventional case series design was used. The sample included 17 children (29 eyes) with primary (19 eyes) or secondary (10 eyes) glaucoma who were treated with augmented trabeculectomy as the primary procedure between 1990 and 2002. Data were collected on age and family history, preoperative and end of follow up intraocular pressure, cup/disc ratio (evaluated by drawing), visual acuity, complications, and post-surgery treatment. Results: Patient age at surgery ranged from 1 month to 8 years; most patients (n=14, 82.3% ) were aged less than 1 year (range 1 month-8 months, mean 3.95 (SD 2.56) months); three patients (17.7% ) were aged3, 5, and 8 years. The duration of follow up was 3- 120 months (mean 46 months). Intraocular pressure significantly improved from 21 mm Hg to 60 mm Hg (mean33.1 (10) mm Hg) before surgery to 6- 26 mm Hg (mean 17.1 (6) mm Hg) after, (P < 0.0001). There was no significant change in cup/disc ratio: 0.1- 0.8 (mean 0.42 (0.26)) before and 0.1- 1.0 (mean 0.511 (0.27)) after (P=0.45). In 22 eyes (75.8% ), intraocular pressure was controlled at less than 20 mm Hg and the cup/disc ratio remained stable or improved. The life table success rate for intraocular pressure control remained stable at 86% at the 12, 24, and 36 months and after 48 months decreased to 53% . There was no significant difference in the life table results between primary and secondary glau coma. 14 eyes (48.2% ) had a visual acuity better than 20/120 by the end of follow up. Repeated surgery was necessary in eight eyes (27.5% ), and additional antiglaucoma treatment in 13 (44.8% ). Complications included retinal detachment 1 year after surgery, choroidal detachment, and blebitis (one eye each). Conclusions: Augmented trabeculectomy with mitomycin C and 5- fluorouracil may serve as the primary procedure in a selected group of paediatric patients with glaucoma.
文摘Objective To examine the reliability of Swedish Interactive Thresholding Algor ithm Fast (SITA Fast) visual fields (VFs) in prepubertal idiopathic intracranial hypertension (IIH) and to compare whether age, gender, or severity of visual outcome influenced the reliability o f VF tests. Design Prospective, longitudinal cohort study. Participants Twenty- six prepubertal children (< 11 years of age; mean age, 7.2 years) with IIH. Test ing Children were prospectively followed up using a childoriented program, which included SITA Fast VF tests. Age, gender, and severity of visual outcome were c orrelated with reliability of performance on SITA Fast VFs using a 1-way analys is of variance, point-biserial correlation, and the chi-square test for indepe ndence of observation. Main outcome measures Statistical analyses results that c orrelated the reliability of SITA Fast VFs with age, gender, and visual outcome. Results Three children were treated at the age of 2 years and were unable to pe rform automated VF tests. Four children were treated at the age of 4 years, 3 of whom were able to perform repeatable reliable SITA Fast VF tests. Forty-two ey es of 21 children had an average SIT AFast test time of 4.5 minutes for each eye , compared with 8 minutes using the Fastpac strategy. Age was not associated wit h reliability scores of SITA Fast tests (F=0.971, not significant ns). Gender did not influence the reliability of SITA Fast VF tests (chi-square(1)=0.669, n s), nor did severity of visual outcome (chi-square(2)=3.348, ns). Visual defici ts were observed in 55%of patients at presentation and in 27%of patients after resolution of papilledema. Conclusions The SITA Fast VF tests can be performed from age 4 years and offer a reliable method for shortening test time. A child- oriented follow-up program, which entails a shortened testing time, may improve outcome in prepubertal IIH.
文摘The purpose of this study was to evaluate the characteristics of automated perimetry exams at a large diagnostic institute. We describe the model of operation of this institue that provides greater than 80% of the visual field examinations, with interpretation, for a population of 2 million people. The institute
文摘Objective: This study was undertaken to compare the effect of antenatal corticosteroid therapy on the risk for severe intraventricular hemorrhage (IVH grade III- IV) in pretermsingleton and multiple very low birth weight (VLBW) infants. Study design:The occurrence of severe IVH was recorded in 5022 singleton,2032 twin, and 582 triplet infants, delivered at 24 to 32 weeks gestation, registered in the Israeli National VLBW infant database. Antenatal corticosteroid therapy was defined as complete,partial, or none. Results: The incidence of IVH grade Ⅲ - IV ranged from 6.8% among singletons receiving complete course to 29.3% in triplets without antenatal corticosteroid treatment.Complete treatment significantly reduced the incidence of IVH in all plurality groups. The adjusted risk for IVH among multiple infants who received a complete course compared with singletons was not significantly different, odds ratio (OR) 1.3,95% CI 1.0- 1.7 for twins and OR 1.5, 95% CI 0.9- 2.3 for triplets.Conclusion: Complete course of antenatal corticosteroid therapy was independently associated with decreased risk for severe IVH in singleton and in multiple preterm VLBW infants.
